@brunolemaitre.bsky.social
Reposted
Bizarre that our 2020 #Drosophila #AMP review already feels out of date.
Thanks to #AnnualReviews to cover the many updates in the field and present a much more complete picture of the diversity, mechanisms, topics, of fly immunity re: host defence peptides.
www.annualreviews.org/content/jour...
Thanks to #AnnualReviews to cover the many updates in the field and present a much more complete picture of the diversity, mechanisms, topics, of fly immunity re: host defence peptides.
www.annualreviews.org/content/jour...
October 24, 2025 at 12:05 PM
Bizarre that our 2020 #Drosophila #AMP review already feels out of date.
Thanks to #AnnualReviews to cover the many updates in the field and present a much more complete picture of the diversity, mechanisms, topics, of fly immunity re: host defence peptides.
www.annualreviews.org/content/jour...
Thanks to #AnnualReviews to cover the many updates in the field and present a much more complete picture of the diversity, mechanisms, topics, of fly immunity re: host defence peptides.
www.annualreviews.org/content/jour...
Reposted
Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...
Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology
As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.
www.nature.com
October 11, 2025 at 8:03 AM
Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...
Reposted
As someone who ended up using non-model systems after doing his PhD with Drosophila, you don't realise just how amazing FlyBase or WormBase are until you try to genetics without them.
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
FlyBase:Contribute to FlyBase - FlyBase Wiki
wiki.flybase.org
August 15, 2025 at 3:13 PM
As someone who ended up using non-model systems after doing his PhD with Drosophila, you don't realise just how amazing FlyBase or WormBase are until you try to genetics without them.
Reposted
I read the preprint. It's very beautiful work from Hadi Boukhatmi's group. They test how if at all #Drosophila can repair their #muscles.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Immune–tracheal intercellular signalling coordinates the muscle injury response in Drosophila
Effective tissue adaptation to damage requires precise coordination among diverse cell types. In skeletal muscle, injury-responsive cells play a pivotal role in repair, yet the molecular and cellular ...
www.biorxiv.org
August 27, 2025 at 5:41 PM
I read the preprint. It's very beautiful work from Hadi Boukhatmi's group. They test how if at all #Drosophila can repair their #muscles.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Currently reading Brave Genomes by Silvia Bulgherisi — a wonderful book on recent advances in genomics, environmental change, and the influence of microbes. Highly recommend!
shop.elsevier.com/books/brave-...
www.amazon.de/Brave-Genome...
shop.elsevier.com/books/brave-...
www.amazon.de/Brave-Genome...
Brave Genomes
The role of environmentally triggered genetic and epigenetic changes in microbial adaptation and evolution is still not broadly appreciated. Brave Gen
shop.elsevier.com
August 27, 2025 at 10:02 AM
Currently reading Brave Genomes by Silvia Bulgherisi — a wonderful book on recent advances in genomics, environmental change, and the influence of microbes. Highly recommend!
shop.elsevier.com/books/brave-...
www.amazon.de/Brave-Genome...
shop.elsevier.com/books/brave-...
www.amazon.de/Brave-Genome...
Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...
Majority of fruit fly immunity studies can be replicated, huge analysis finds
Verification of 50 years of data bolsters immunology research, but identifies “suspicious” papers that don’t hold up
www.science.org
July 16, 2025 at 8:01 AM
Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...
Reposted
the strain on academic publishing could be substantially alleviated if funding agencies stipulated... work they support must be published in non-profit journals.
Hanson believes the problem is not open access & APCs per se, but for-profit publishers that seek to publish as many papers as possible... the strain on academic publishing could be substantially alleviated if funding agencies stipulated... work they support must be published in non-profit journals.
Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published
Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention
www.theguardian.com
July 15, 2025 at 2:26 PM
the strain on academic publishing could be substantially alleviated if funding agencies stipulated... work they support must be published in non-profit journals.
Reposted
Specifically on the #metascience side, congrats to @josephlemaitre.bsky.social and @brunolemaitre.bsky.social on this consequential piece. 🎉
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
July 10, 2025 at 12:58 PM
Specifically on the #metascience side, congrats to @josephlemaitre.bsky.social and @brunolemaitre.bsky.social on this consequential piece. 🎉
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
Reposted
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
July 10, 2025 at 8:23 AM
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
Reposted
Congratulations to @fly-eds.bsky.social board member Gábor Juhász @juhg.hu and to Oren Schuldiner @schuldinerorenlab.bsky.social for their election to EMBO membership!
#Drosophila
#Drosophila
Welcome and congratulations to the 60 new members and 9 associate members who have been elected to the EMBO Membership! This honour celebrates #research excellence and outstanding achievements in the #LifeSciences. 🧪
Learn more here:
www.embo.org/press-releas... #EMBOMembers2025
Learn more here:
www.embo.org/press-releas... #EMBOMembers2025
Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO
Sixty-nine new members join the community of leading life scientists in Europe and beyond
www.embo.org
July 2, 2025 at 1:49 PM
Congratulations to @fly-eds.bsky.social board member Gábor Juhász @juhg.hu and to Oren Schuldiner @schuldinerorenlab.bsky.social for their election to EMBO membership!
#Drosophila
#Drosophila
Reposted
#FlyCROSS is a mentor-mentee matching program for the fly community. They're looking for mentors from all career paths (academia, industry, policy etc.) who have experience with #Drosophila research and are eager to support the next generation of fly scientists.
Apply to become a mentor by 14 July:
Apply to become a mentor by 14 July:
FlyCROSS 2025–26: Mentor-mentee matching program - the Node
Call for Mentors from the Drosophila community. The Fly Board is excited to announce the second cycle of FlyCROSS (2025–2026), following a successful
thenode.biologists.com
June 26, 2025 at 2:44 PM
#FlyCROSS is a mentor-mentee matching program for the fly community. They're looking for mentors from all career paths (academia, industry, policy etc.) who have experience with #Drosophila research and are eager to support the next generation of fly scientists.
Apply to become a mentor by 14 July:
Apply to become a mentor by 14 July:
Reposted
Michael Ashburner FRS was an influential figure in the fields of Drosophila genomics and early sequencing database initiatives such as @ebi.embl.org.
Read about their contributions across genetics and bioinformatics in the new biographical memoir: buff.ly/f01zNat
@geneticscam.bsky.social
Read about their contributions across genetics and bioinformatics in the new biographical memoir: buff.ly/f01zNat
@geneticscam.bsky.social
June 17, 2025 at 10:44 AM
Michael Ashburner FRS was an influential figure in the fields of Drosophila genomics and early sequencing database initiatives such as @ebi.embl.org.
Read about their contributions across genetics and bioinformatics in the new biographical memoir: buff.ly/f01zNat
@geneticscam.bsky.social
Read about their contributions across genetics and bioinformatics in the new biographical memoir: buff.ly/f01zNat
@geneticscam.bsky.social
Reposted
Hidden virus harboured by fruit flies may influence experimental accuracy.
buff.ly/TtHCYLQ
buff.ly/TtHCYLQ
June 13, 2025 at 8:02 PM
Hidden virus harboured by fruit flies may influence experimental accuracy.
buff.ly/TtHCYLQ
buff.ly/TtHCYLQ
Reposted
Oh man, you guys. This is so important. Drosophila have led to so much in terms of what we understand about how genes work.
#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 8:03 PM
Oh man, you guys. This is so important. Drosophila have led to so much in terms of what we understand about how genes work.
Reposted
Big #Drosophila news!🪰
The AMP mutant lines from Hanson et al. (elifesciences.org/articles/443...) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social's group are now in @vdrc-flies.bsky.social!
Find the 40 DrosDel Immunity Panel strains at ⬇️
The AMP mutant lines from Hanson et al. (elifesciences.org/articles/443...) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social's group are now in @vdrc-flies.bsky.social!
Find the 40 DrosDel Immunity Panel strains at ⬇️
shop.vbc.ac.at
May 15, 2025 at 9:36 PM
Big #Drosophila news!🪰
The AMP mutant lines from Hanson et al. (elifesciences.org/articles/443...) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social's group are now in @vdrc-flies.bsky.social!
Find the 40 DrosDel Immunity Panel strains at ⬇️
The AMP mutant lines from Hanson et al. (elifesciences.org/articles/443...) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social's group are now in @vdrc-flies.bsky.social!
Find the 40 DrosDel Immunity Panel strains at ⬇️
We are happy to annouce that we have deposited at @VDRC
(ViennaDrosophila Resource Center) a list of isogenized @Drosophila immunity mutants affecting all major immune modules and effectors. We hope these strains will be useful to the community.
epfl.ch/labs/lemaitr...
(ViennaDrosophila Resource Center) a list of isogenized @Drosophila immunity mutants affecting all major immune modules and effectors. We hope these strains will be useful to the community.
epfl.ch/labs/lemaitr...
May 28, 2025 at 2:43 PM
We are happy to annouce that we have deposited at @VDRC
(ViennaDrosophila Resource Center) a list of isogenized @Drosophila immunity mutants affecting all major immune modules and effectors. We hope these strains will be useful to the community.
epfl.ch/labs/lemaitr...
(ViennaDrosophila Resource Center) a list of isogenized @Drosophila immunity mutants affecting all major immune modules and effectors. We hope these strains will be useful to the community.
epfl.ch/labs/lemaitr...
Reposted
Sad news. Benny Shilo, a pioneer in dev bio & Drosophila genetics, has died.
I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.
I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.
Our field has lost an amazing scientist, mentor, and old friend. Benny, along with Mike Hoffman, had a brilliant idea in the early 1980s. The first oncogenes were being cloned and they realized if we wanted to understand their roles in cancer, we needed to understand their normal function 1/n 🧪
April 17, 2025 at 10:06 AM
Sad news. Benny Shilo, a pioneer in dev bio & Drosophila genetics, has died.
I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.
I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.
Reposted
Some hashtags:
#immunity #Dros25 #Drosophila #antimicrobialpeptides #NFkB #inflammation #ImmunoSky #Infection #pathogen
And if you want to learn more about these modules and how you could incorporate them in your research, check our our free book: "The Drosophila Immunity Handbook"
bit.ly/3z429p5
#immunity #Dros25 #Drosophila #antimicrobialpeptides #NFkB #inflammation #ImmunoSky #Infection #pathogen
And if you want to learn more about these modules and how you could incorporate them in your research, check our our free book: "The Drosophila Immunity Handbook"
bit.ly/3z429p5
April 1, 2025 at 8:34 AM
Some hashtags:
#immunity #Dros25 #Drosophila #antimicrobialpeptides #NFkB #inflammation #ImmunoSky #Infection #pathogen
And if you want to learn more about these modules and how you could incorporate them in your research, check our our free book: "The Drosophila Immunity Handbook"
bit.ly/3z429p5
#immunity #Dros25 #Drosophila #antimicrobialpeptides #NFkB #inflammation #ImmunoSky #Infection #pathogen
And if you want to learn more about these modules and how you could incorporate them in your research, check our our free book: "The Drosophila Immunity Handbook"
bit.ly/3z429p5
Reposted
Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity.
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Layers of immunity: Deconstructing the Drosophila effector response
The host innate immune response relies on the cooperation of multiple defense modules. In insects and other arthropods, which have only innate immune mechanisms, four main immune-specific modules cont...
www.biorxiv.org
April 1, 2025 at 8:34 AM
Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity.
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Does marrying a fellow scientist boost your career?
In academia, homogamous couples—where both partners are scientists—are common, especially among top achievers. But who benefits more? Let’s dive into our latest research!
In academia, homogamous couples—where both partners are scientists—are common, especially among top achievers. But who benefits more? Let’s dive into our latest research!
March 21, 2025 at 2:33 PM
Does marrying a fellow scientist boost your career?
In academia, homogamous couples—where both partners are scientists—are common, especially among top achievers. But who benefits more? Let’s dive into our latest research!
In academia, homogamous couples—where both partners are scientists—are common, especially among top achievers. But who benefits more? Let’s dive into our latest research!
Reposted
Recently completed your #PhD using #Drosophila in a European lab? Apply for the European Drosophila Society best thesis prize!
🏆🪰
Deadline: 28 Feb 2025.
Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025.bsky.social!
Info here: europeandrosophilasociety.org/eds-best-phd...
🏆🪰
Deadline: 28 Feb 2025.
Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025.bsky.social!
Info here: europeandrosophilasociety.org/eds-best-phd...
EDS best PhD thesis prize | European Drosophila SocietyHome
europeandrosophilasociety.org
February 20, 2025 at 3:30 PM
Recently completed your #PhD using #Drosophila in a European lab? Apply for the European Drosophila Society best thesis prize!
🏆🪰
Deadline: 28 Feb 2025.
Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025.bsky.social!
Info here: europeandrosophilasociety.org/eds-best-phd...
🏆🪰
Deadline: 28 Feb 2025.
Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025.bsky.social!
Info here: europeandrosophilasociety.org/eds-best-phd...
Reposted
Workshop on ecological & evolutionary immunology/insect immunity. 15-19th Sept 2025 - Werbellinsee, Germany, organised by Sophie Armitage and Jens Rolff. Abstract deadline start of March www.bcp.fu-berlin.de/en/biologie/...
Home
www.bcp.fu-berlin.de
January 28, 2025 at 10:23 AM
Workshop on ecological & evolutionary immunology/insect immunity. 15-19th Sept 2025 - Werbellinsee, Germany, organised by Sophie Armitage and Jens Rolff. Abstract deadline start of March www.bcp.fu-berlin.de/en/biologie/...
We are recruiting one postdoc and one PhD student to join our lab on #Drosophila #innate immunity in Lausanne (Switzerland). More info: www.epfl.ch/labs/lemaitr...
Open Positions
-
www.epfl.ch
January 20, 2025 at 9:53 AM
We are recruiting one postdoc and one PhD student to join our lab on #Drosophila #innate immunity in Lausanne (Switzerland). More info: www.epfl.ch/labs/lemaitr...
Reposted
The European Drosophila Society @fly-eds.bsky.social has just launched a #prize to the best #PhD thesis using #Drosophila.
🏆🪰
Deadline is Feb 2025.
Prize = €1000 & keynote presentation at the #EDRC2025 @edrc2025.bsky.social !
More info here: europeandrosophilasociety.org/eds-best-phd...
🏆🪰
Deadline is Feb 2025.
Prize = €1000 & keynote presentation at the #EDRC2025 @edrc2025.bsky.social !
More info here: europeandrosophilasociety.org/eds-best-phd...
EDS best PhD thesis prize | European Drosophila SocietyHome
europeandrosophilasociety.org
December 11, 2024 at 3:42 PM
The European Drosophila Society @fly-eds.bsky.social has just launched a #prize to the best #PhD thesis using #Drosophila.
🏆🪰
Deadline is Feb 2025.
Prize = €1000 & keynote presentation at the #EDRC2025 @edrc2025.bsky.social !
More info here: europeandrosophilasociety.org/eds-best-phd...
🏆🪰
Deadline is Feb 2025.
Prize = €1000 & keynote presentation at the #EDRC2025 @edrc2025.bsky.social !
More info here: europeandrosophilasociety.org/eds-best-phd...
Reposted
I am so sad to lose Dr. Ruth Steward. She was a groundbreaking scientist and a fierce role model for #WomenInScience. This photo is our dinner group with seminar speaker @rburdine1.bsky.social and @lacefieldlab.bsky.social @schindlerlab.bsky.social (1/27/2020). May her memory be an inspiration.
January 6, 2025 at 11:38 PM
I am so sad to lose Dr. Ruth Steward. She was a groundbreaking scientist and a fierce role model for #WomenInScience. This photo is our dinner group with seminar speaker @rburdine1.bsky.social and @lacefieldlab.bsky.social @schindlerlab.bsky.social (1/27/2020). May her memory be an inspiration.