Da-Neng Wang
@danengw.bsky.social
Structural biologist, professor, NYU School of Medicine. Alum of: Skirball Institute, EMBL, Univ Stockholm, Acad Sin, NEU. Personal account. https://scholar.google.com/citations?user=lX2sB0sAAAAJ&hl=en
Reposted by Da-Neng Wang
Excited to share our latest @nature.com: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation.💊🧪 🧵👇 www.nature.com/articles/s41...
November 5, 2025 at 4:23 PM
Excited to share our latest @nature.com: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation.💊🧪 🧵👇 www.nature.com/articles/s41...
Reposted by Da-Neng Wang
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Quick Check Needed
mrc.tal.net
October 29, 2025 at 9:17 AM
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Reposted by Da-Neng Wang
New online: New York City’s structural biology mosaic
New York City’s structural biology mosaic
Nature Structural & Molecular Biology, Published online: 28 October 2025; doi:10.1038/s41594-025-01698-zThe structural biology community in New York City combines expertise and access to cutting-edge instrumentation that fosters cooperation. Working collaboratively is indispensable because developing interdisciplinary tools can enable discoveries in cell, structural and molecular biology.
go.nature.com
October 28, 2025 at 11:45 AM
New online: New York City’s structural biology mosaic
Reposted by Da-Neng Wang
#EPFL has an open faculty position - tenure track or tenured!! - in AI driven biophysics. Deadline is Nov 15th. Please spread the word!
www.epfl.ch/about/workin...
www.epfl.ch/about/workin...
Assistant/associate Professor of AI-assisted Biophysics at the Ecole polytechnique fédérale de Lausanne (EPFL) and Group Leader at the Paul Scherrer Institute (PSI)
The School of Basic Sciences (Physics, Chemistry and Mathematics) at EPFL and the Paul Scherrer Institute (PSI) jointly seek to appoint a Tenure Track Assistant or tenured Associate Professor in AI-As...
www.epfl.ch
October 28, 2025 at 2:56 AM
#EPFL has an open faculty position - tenure track or tenured!! - in AI driven biophysics. Deadline is Nov 15th. Please spread the word!
www.epfl.ch/about/workin...
www.epfl.ch/about/workin...
Reposted by Da-Neng Wang
Fred Hutch's Human Biology Division is recruiting an Assistant or Associate Professor to lead a laboratory-based research program focused on the biological mechanisms of solid tumor cancers and their clinical translation. Learn more and apply: https://apply.interfolio.com/174007
October 25, 2025 at 5:16 PM
Fred Hutch's Human Biology Division is recruiting an Assistant or Associate Professor to lead a laboratory-based research program focused on the biological mechanisms of solid tumor cancers and their clinical translation. Learn more and apply: https://apply.interfolio.com/174007
Reposted by Da-Neng Wang
Chris Russo and Anastasiia Gusach have developed a new method to prepare #cryoEM samples that avoids protein damage during freezing
Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...
#LMBResearch
Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...
#LMBResearch
October 22, 2025 at 4:41 PM
Chris Russo and Anastasiia Gusach have developed a new method to prepare #cryoEM samples that avoids protein damage during freezing
Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...
#LMBResearch
Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...
#LMBResearch
Reposted by Da-Neng Wang
Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887
Please apply and/or share this post.
Please apply and/or share this post.
Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
October 17, 2025 at 11:23 PM
Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887
Please apply and/or share this post.
Please apply and/or share this post.
Reposted by Da-Neng Wang
UGA is seeking a tenure-track Assistant Professor to develop an innovative research program focused on disease mechanisms. The ideal candidate will use cryo-EM and other structural techniques, with potential applications to future therapies.
Apply here: www.ugajobsearch.com/postings/456...
Apply here: www.ugajobsearch.com/postings/456...
Assistant Professor of Structural Biology
The Franklin College of Arts and Sciences at the University of Georgia (UGA) invites applications for multiple open faculty positions, beginning August 1, 2026. We are broadly interested in scientists...
www.ugajobsearch.com
October 22, 2025 at 3:35 PM
UGA is seeking a tenure-track Assistant Professor to develop an innovative research program focused on disease mechanisms. The ideal candidate will use cryo-EM and other structural techniques, with potential applications to future therapies.
Apply here: www.ugajobsearch.com/postings/456...
Apply here: www.ugajobsearch.com/postings/456...
Reposted by Da-Neng Wang
The Department of Biochemistry and Molecular Biology at UTHealth Houston has an open search for a tenure-track faculty position. If you are ready (or know someone that is) to start looking for positions, this will be a great opportunity to join the Texas Medical Center. See flyer below. 1/2
October 21, 2025 at 9:47 PM
The Department of Biochemistry and Molecular Biology at UTHealth Houston has an open search for a tenure-track faculty position. If you are ready (or know someone that is) to start looking for positions, this will be a great opportunity to join the Texas Medical Center. See flyer below. 1/2
Reposted by Da-Neng Wang
Learn how our hunt for the native structure of top antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms.nature.com 👉 rdcu.be/eLRlH 🦠🔬❄️
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
Endogenous structure of antimalarial target PfATP4 reveals an apicomplexan-specific P-type ATPase modulator
Nature Communications - Here, the authors present the 3.7 Å cryoEM structure of native sodium efflux pump PfATP4 from Plasmodium falciparum, revealing a bound protein that they term...
rdcu.be
October 20, 2025 at 12:55 PM
Learn how our hunt for the native structure of top antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms.nature.com 👉 rdcu.be/eLRlH 🦠🔬❄️
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria
Reposted by Da-Neng Wang
Collaborative. Creative. Impactful. Come join us in Ann Arbor! For more information and application link see jobs.sciencecareers.org/job/675674/f...
October 19, 2025 at 5:53 PM
Collaborative. Creative. Impactful. Come join us in Ann Arbor! For more information and application link see jobs.sciencecareers.org/job/675674/f...
Reposted by Da-Neng Wang
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for genetic code expansion - Nature
Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...
www.nature.com
October 16, 2025 at 2:06 PM
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Reposted by Da-Neng Wang
Nominations for the June Almeida award for Mid/Senior-Career Women in Cryo-EM are now open! Submit your nomination via this link www.biophysics.org/awards-fundi... by November 14th to recognize an exceptional woman in our community.
Subgroup Awards - The Biophysical Society
www.biophysics.org
October 16, 2025 at 7:08 PM
Nominations for the June Almeida award for Mid/Senior-Career Women in Cryo-EM are now open! Submit your nomination via this link www.biophysics.org/awards-fundi... by November 14th to recognize an exceptional woman in our community.
Reposted by Da-Neng Wang
Nobel Laureate Joachim Frank: "I will not be bookended by two fascist regimes." An impactful must-read. www.usnews.com/opinion/arti...
www.usnews.com
October 11, 2025 at 11:49 AM
Nobel Laureate Joachim Frank: "I will not be bookended by two fascist regimes." An impactful must-read. www.usnews.com/opinion/arti...
Reposted by Da-Neng Wang
Reposted by Da-Neng Wang
Reposted by Da-Neng Wang
The Rutgers Brain Health Institute @rutgersbhi.bsky.social is looking for an accomplished scientist to serve as the Director of the new Rutgers Center on Research in Pain and Pain Therapeutics. Feel free re-post and/or reach out to me if you have any questions
jobs.rutgers.edu/postings/225...
jobs.rutgers.edu/postings/225...
Director of Center on Research in Pain and Pain Therapeutics at Rutgers Brain Health Institute
We seek an accomplished scientist, at the Professor or Associate Professor level, to join the Rutgers Brain Health Institute (BHI) and The Rutgers School of Dental Medicine (RSDM) as Director of the n...
jobs.rutgers.edu
October 8, 2025 at 3:22 PM
The Rutgers Brain Health Institute @rutgersbhi.bsky.social is looking for an accomplished scientist to serve as the Director of the new Rutgers Center on Research in Pain and Pain Therapeutics. Feel free re-post and/or reach out to me if you have any questions
jobs.rutgers.edu/postings/225...
jobs.rutgers.edu/postings/225...
Reposted by Da-Neng Wang
EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬
The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩🔬🤓
The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩🔬🤓
September 30, 2025 at 9:52 AM
EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬
The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩🔬🤓
The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩🔬🤓
Reposted by Da-Neng Wang
We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...
biochem.weill.cornell.edu/join-our-fac...
Join our Faculty | Department of Biochemistry & Biophysics
Call for applications:We invite applications for a tenure-track Assistant Professor position in the newly established Department of Biochemistry and Biophysics. We are conducting an open search for ou...
biochem.weill.cornell.edu
September 29, 2025 at 7:58 PM
We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...
biochem.weill.cornell.edu/join-our-fac...
Reposted by Da-Neng Wang
Thank you all the program officers at NIH that persisted through the 2025 fiscal year and were able to fund 99% of the total FY2024 budget. I know this has take a toll on everyone at NIH. Thank you for supporting important health and behavior science and helping to keep the U.S. a leader in science.
The fiscal year ends tomorrow.
Here are results from NIH Reporter downloaded an hour ago.
The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors.
1/3
Here are results from NIH Reporter downloaded an hour ago.
The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors.
1/3
September 29, 2025 at 5:51 PM
Thank you all the program officers at NIH that persisted through the 2025 fiscal year and were able to fund 99% of the total FY2024 budget. I know this has take a toll on everyone at NIH. Thank you for supporting important health and behavior science and helping to keep the U.S. a leader in science.
Reposted by Da-Neng Wang
This paper does a great job with a "It's a Wonderful Life" scenario about NIH, supposing the consequences of the bottom 40% of the funding NIH grants never existed.
www.science.org/doi/10.1126/...
tl:dr The world would lose a lot, but directly and indirectly
www.science.org/doi/10.1126/...
tl:dr The world would lose a lot, but directly and indirectly
What if NIH had been 40% smaller?
Replaying history with less NIH funding shows widespread impacts on drug-linked research
www.science.org
September 26, 2025 at 11:01 AM
This paper does a great job with a "It's a Wonderful Life" scenario about NIH, supposing the consequences of the bottom 40% of the funding NIH grants never existed.
www.science.org/doi/10.1126/...
tl:dr The world would lose a lot, but directly and indirectly
www.science.org/doi/10.1126/...
tl:dr The world would lose a lot, but directly and indirectly
Congratulations, Yifan, for the Anatrace Award! Yifan’s work on the TRPV1 structure with David Julius helped launch the Resolution Revolution in cryo-EM. Not just in membrane proteins—hardly any area of biophysics today has remained untouched by the techniques Yifan pioneered.
Yifan Cheng to Receive 2026 Anatrace Membrane Protein Award buff.ly/ooI1UDy
September 24, 2025 at 10:09 PM
Congratulations, Yifan, for the Anatrace Award! Yifan’s work on the TRPV1 structure with David Julius helped launch the Resolution Revolution in cryo-EM. Not just in membrane proteins—hardly any area of biophysics today has remained untouched by the techniques Yifan pioneered.
Congratulations, Nuria! For many years, Nuria ran the Biochemistry and Biophysics of Membranes study section at the NIH. She trained generations of reviewers and taught many of us how to write a better grant.
September 24, 2025 at 10:07 PM
Congratulations, Nuria! For many years, Nuria ran the Biochemistry and Biophysics of Membranes study section at the NIH. She trained generations of reviewers and taught many of us how to write a better grant.
Reposted by Da-Neng Wang
🚨🧠🔬 A major breakthrough in molecular neuroscience:
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
September 16, 2025 at 4:47 PM
🚨🧠🔬 A major breakthrough in molecular neuroscience:
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz