Mackenzie Weygandt Mathis
@trackingactions.bsky.social
Scientist 👩🔬 & EPFL Prof 🇨🇭 | DeepLabCut.org , 🦓 cebra.ai | neuroscience & ML 🧠 mackenziemathislab.org | ✨CSO at Kinematik.ai | occasionally 🐦⬛birds/🌱outdoors/🍣food/👠fashion
Reposted by Mackenzie Weygandt Mathis
AI tools like DeepLabCut and SuperAnimal are changing how scientists study movement, helping them understand how brain activity drives behavior.
Read more: bit.ly/4qnX7JF
@trackingactions.bsky.social @deeplabcut.bsky.social
Read more: bit.ly/4qnX7JF
@trackingactions.bsky.social @deeplabcut.bsky.social
How AI Is Changing Neuroscience Discovery
AI is altering how scientists study the brain
bit.ly
November 1, 2025 at 12:07 AM
AI tools like DeepLabCut and SuperAnimal are changing how scientists study movement, helping them understand how brain activity drives behavior.
Read more: bit.ly/4qnX7JF
@trackingactions.bsky.social @deeplabcut.bsky.social
Read more: bit.ly/4qnX7JF
@trackingactions.bsky.social @deeplabcut.bsky.social
#EPFL has an open faculty position - tenure track or tenured!! - in AI driven biophysics. Deadline is Nov 15th. Please spread the word!
www.epfl.ch/about/workin...
www.epfl.ch/about/workin...
Assistant/associate Professor of AI-assisted Biophysics at the Ecole polytechnique fédérale de Lausanne (EPFL) and Group Leader at the Paul Scherrer Institute (PSI)
The School of Basic Sciences (Physics, Chemistry and Mathematics) at EPFL and the Paul Scherrer Institute (PSI) jointly seek to appoint a Tenure Track Assistant or tenured Associate Professor in AI-As...
www.epfl.ch
October 28, 2025 at 2:56 AM
#EPFL has an open faculty position - tenure track or tenured!! - in AI driven biophysics. Deadline is Nov 15th. Please spread the word!
www.epfl.ch/about/workin...
www.epfl.ch/about/workin...
Reposted by Mackenzie Weygandt Mathis
My lab has been pushing into explainable, robust, & theoretically-tractable AI models for science 💪
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
August 25, 2025 at 7:44 AM
My lab has been pushing into explainable, robust, & theoretically-tractable AI models for science 💪
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
Reposted by Mackenzie Weygandt Mathis
(YouTube) From LSD to AI with Switzerland's brain explorers www.youtube.com/watch?v=HqnA... via @trackingactions.bsky.social
From LSD to AI with Switzerland's Brain Explorers | Hello World with Ashlee Vance
YouTube video by Bloomberg Originals
www.youtube.com
October 9, 2025 at 6:06 PM
(YouTube) From LSD to AI with Switzerland's brain explorers www.youtube.com/watch?v=HqnA... via @trackingactions.bsky.social
Reposted by Mackenzie Weygandt Mathis
Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Motor cortex flexibly deploys a high-dimensional repertoire of subskills
Skilled movement often requires flexibly combining multiple subskills, each requiring dedicated control strategies and underlying computations. How the motor system achieves such versatility remains u...
www.biorxiv.org
September 8, 2025 at 4:34 PM
Of potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Mackenzie Weygandt Mathis
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 24, 2025 at 12:04 PM
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Fall US trips booked! I'll be speaking at Scripps, SfN, and ICCV 🚀 Who will be at #ScrippsNeuroSymposium2025, #SfN2025 and/or #ICCV2025? Lots of ☀️🕶️🌴 & 🧠 in Oct/Nov!
September 23, 2025 at 3:12 PM
Fall US trips booked! I'll be speaking at Scripps, SfN, and ICCV 🚀 Who will be at #ScrippsNeuroSymposium2025, #SfN2025 and/or #ICCV2025? Lots of ☀️🕶️🌴 & 🧠 in Oct/Nov!
Not just an amazing dataset, excellent 3D pose, shape, and eye tracking in the real world! Bravo @trackingskills.bsky.social et al!
PS - Exactly this kind of data we predict will be critical for long-term health monitoring @monosovlab.bsky.social et al: www.sciencedirect.com/science/arti...
PS - Exactly this kind of data we predict will be critical for long-term health monitoring @monosovlab.bsky.social et al: www.sciencedirect.com/science/arti...
September 23, 2025 at 7:42 AM
Not just an amazing dataset, excellent 3D pose, shape, and eye tracking in the real world! Bravo @trackingskills.bsky.social et al!
PS - Exactly this kind of data we predict will be critical for long-term health monitoring @monosovlab.bsky.social et al: www.sciencedirect.com/science/arti...
PS - Exactly this kind of data we predict will be critical for long-term health monitoring @monosovlab.bsky.social et al: www.sciencedirect.com/science/arti...
Reposted by Mackenzie Weygandt Mathis
A.I. tools are already shaping patient care—but we should be wary of letting them diagnose us. “Patients and doctors alike could think of A.I. not as a way to solve mysteries but as a way to gather clues,” Dhruv Khullar writes.
If A.I. Can Diagnose Patients, What Are Doctors For?
Large language models are transforming medicine—but the technology comes with side effects.
www.newyorker.com
September 22, 2025 at 2:44 PM
A.I. tools are already shaping patient care—but we should be wary of letting them diagnose us. “Patients and doctors alike could think of A.I. not as a way to solve mysteries but as a way to gather clues,” Dhruv Khullar writes.
Reposted by Mackenzie Weygandt Mathis
New preprint alert! The uterus expands ~500-fold in pregnancy, yet we know little about how pressures are sensed. Led by @yunxiao-dr.bsky.social, we show PIEZOs are required for contractions and birth in mice, with dual roles of PIEZO1 in muscle and PIEZO2 in neurons
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
PIEZO channels link mechanical forces to uterine contractions in parturition
Mechanical forces are extensively involved in pregnancy and parturition, but their precise roles and mechanisms remain poorly understood. Here, we identify mechanically activated ion channels PIEZO1 a...
www.biorxiv.org
September 18, 2025 at 3:23 PM
New preprint alert! The uterus expands ~500-fold in pregnancy, yet we know little about how pressures are sensed. Led by @yunxiao-dr.bsky.social, we show PIEZOs are required for contractions and birth in mice, with dual roles of PIEZO1 in muscle and PIEZO2 in neurons
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Mackenzie Weygandt Mathis
DeepLabCut pose estimation (@trackingactions.bsky.social) revealed high intitial motor variability, which is essenatial for motor learning (Dhawale et al., 2017, Annu. Rev. Neurosci.).
September 11, 2025 at 10:15 AM
DeepLabCut pose estimation (@trackingactions.bsky.social) revealed high intitial motor variability, which is essenatial for motor learning (Dhawale et al., 2017, Annu. Rev. Neurosci.).
Reposted by Mackenzie Weygandt Mathis
New paper in Nature finds that global geologic CO2 storage potential is ~90% lower than previously believed. Many candidate sites could leak CO2 back into the air or into groundwater, undermining climate mitigation efficacy or putting nearby human health at risk.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A prudent planetary limit for geologic carbon storage - Nature
A risk-based, spatially explicit analysis of carbon storage in sedimentary basins establishes a prudent planetary limit of around 1,460 Gt of geological carbon storage, which requires making explicit ...
www.nature.com
September 4, 2025 at 9:02 AM
New paper in Nature finds that global geologic CO2 storage potential is ~90% lower than previously believed. Many candidate sites could leak CO2 back into the air or into groundwater, undermining climate mitigation efficacy or putting nearby human health at risk.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
I might be biased, but I think this is one of the most exciting developments in generalized musculoskeletal control in years ⬇️. Congrats to the team (I’m not involved!) 💪🔥
Something exciting just left the gym -- meet Arnold the first generalist musculoskeletal control policy!
The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066
The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066
September 4, 2025 at 11:05 AM
I might be biased, but I think this is one of the most exciting developments in generalized musculoskeletal control in years ⬇️. Congrats to the team (I’m not involved!) 💪🔥
Reposted by Mackenzie Weygandt Mathis
Something exciting just left the gym -- meet Arnold the first generalist musculoskeletal control policy!
The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066
The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066
September 4, 2025 at 8:45 AM
Something exciting just left the gym -- meet Arnold the first generalist musculoskeletal control policy!
The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066
The human body has 600+ muscles, yet we seamlessly coordinate them for everything from whispering a syllable to felling a forrest. How? www.arxiv.org/abs/2508.18066
Reposted by Mackenzie Weygandt Mathis
Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.
Mice navigate scent trails using predictive policies
Animals actively sense their environment to extract features of interest to guide behaviors. For mammals, odors are prominent environmental features which are sampled by active modulation of sniffing ...
www.biorxiv.org
September 1, 2025 at 7:06 PM
Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.
Reposted by Mackenzie Weygandt Mathis
EPFL, ETH Zurich & CSCS just released Apertus, Switzerland’s first fully open-source large language model.
Trained on 15T tokens in 1,000+ languages, it’s built for transparency, responsibility & the public good.
Read more: actu.epfl.ch/news/apertus...
Trained on 15T tokens in 1,000+ languages, it’s built for transparency, responsibility & the public good.
Read more: actu.epfl.ch/news/apertus...
September 2, 2025 at 11:48 AM
EPFL, ETH Zurich & CSCS just released Apertus, Switzerland’s first fully open-source large language model.
Trained on 15T tokens in 1,000+ languages, it’s built for transparency, responsibility & the public good.
Read more: actu.epfl.ch/news/apertus...
Trained on 15T tokens in 1,000+ languages, it’s built for transparency, responsibility & the public good.
Read more: actu.epfl.ch/news/apertus...
This was a wonderful project to work on! It also, in part, sparked a lot!
Beyond just our handles: @trackingskills.bsky.social aka trackingplumes (Bluesky and X), when I wanted to track mouse hands & Alex noses, we teamed up in 2017 to make @deeplabcut.bsky.social 💜
Delighted to see this out! 🙏🏼
Beyond just our handles: @trackingskills.bsky.social aka trackingplumes (Bluesky and X), when I wanted to track mouse hands & Alex noses, we teamed up in 2017 to make @deeplabcut.bsky.social 💜
Delighted to see this out! 🙏🏼
September 2, 2025 at 8:10 AM
This was a wonderful project to work on! It also, in part, sparked a lot!
Beyond just our handles: @trackingskills.bsky.social aka trackingplumes (Bluesky and X), when I wanted to track mouse hands & Alex noses, we teamed up in 2017 to make @deeplabcut.bsky.social 💜
Delighted to see this out! 🙏🏼
Beyond just our handles: @trackingskills.bsky.social aka trackingplumes (Bluesky and X), when I wanted to track mouse hands & Alex noses, we teamed up in 2017 to make @deeplabcut.bsky.social 💜
Delighted to see this out! 🙏🏼
Reposted by Mackenzie Weygandt Mathis
Yes, AmadeusGPT is a great example of the kinds of structure that can make these LLMs truly useful for science
August 25, 2025 at 4:00 PM
Yes, AmadeusGPT is a great example of the kinds of structure that can make these LLMs truly useful for science
Selfishly, I’ll plug our tool LLM agent in system #AmadeusGPT - which lets you vibe code your behavioral analysis ;) and even gives you interpretable and verifiable outputs!
www.mackenziemathislab.org/amadeusgpt
www.mackenziemathislab.org/amadeusgpt
August 25, 2025 at 12:55 PM
Selfishly, I’ll plug our tool LLM agent in system #AmadeusGPT - which lets you vibe code your behavioral analysis ;) and even gives you interpretable and verifiable outputs!
www.mackenziemathislab.org/amadeusgpt
www.mackenziemathislab.org/amadeusgpt
My lab has been pushing into explainable, robust, & theoretically-tractable AI models for science 💪
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
August 25, 2025 at 7:44 AM
My lab has been pushing into explainable, robust, & theoretically-tractable AI models for science 💪
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
New! Accepted to #ICCV2025 we introduce #DISTIL - led by amazing PhD student @mirzious.bsky.social - we propose a trigger-inversion method for DNNs that reconstructs malicious backdoor triggers 1/4
Reposted by Mackenzie Weygandt Mathis
A no-miss opportunity to join EPFL. We are a vibrant (had to use it 😉) community working in all branches of basic sciences and engineering, and interdisciplinary studies are strongly encouraged.
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
Assistant/associate Professor of AI-assisted Biophysics at the Ecole polytechnique fédérale de Lausanne (EPFL) and Group Leader at the Paul Scherrer Institute (PSI)
The School of Basic Sciences (Physics, Chemistry and Mathematics) at EPFL and the Paul Scherrer Institute (PSI) jointly seek to appoint a Tenure Track Assistant or tenured Associate Professor in AI-As...
tinyurl.com
August 21, 2025 at 6:35 AM
A no-miss opportunity to join EPFL. We are a vibrant (had to use it 😉) community working in all branches of basic sciences and engineering, and interdisciplinary studies are strongly encouraged.
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
If you want more information, contact the committee heads, or feel free to DM me.
tinyurl.com/bd27ky7p
So great to meet up with the talented @julianneumann.bsky.social today! His work on merging neuro, AI, and clinical applications is very exciting. He was the first to use and extend #CEBRA for human experiments 🚀🧠 #neuroskynce
August 19, 2025 at 10:10 AM
So great to meet up with the talented @julianneumann.bsky.social today! His work on merging neuro, AI, and clinical applications is very exciting. He was the first to use and extend #CEBRA for human experiments 🚀🧠 #neuroskynce
Reposted by Mackenzie Weygandt Mathis
The Sudmant lab at UC Berkeley is seeking a postdoc to work on a fully funded NIH project to understand differences in DNA repair and somatic mutation across the primate tree of life. Please spread widely to those who may be interested aprecruit.berkeley.edu/JPF05052
Postdoctoral Scholar – Genomics, Aging, Somatic Mutation, Structural Variation, Evolution , Cancer – Integrative Biology
University of California, Berkeley is hiring. Apply now!
aprecruit.berkeley.edu
August 13, 2025 at 4:22 AM
The Sudmant lab at UC Berkeley is seeking a postdoc to work on a fully funded NIH project to understand differences in DNA repair and somatic mutation across the primate tree of life. Please spread widely to those who may be interested aprecruit.berkeley.edu/JPF05052
Reposted by Mackenzie Weygandt Mathis
1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
RFK Jr. in interview with Scripps News: ‘Trusting the experts is not science’
HHS Secretary RFK Jr. sat down with Scripps News for a wide-ranging interview, discussing mRNA vaccine funding policy changes and a recent shooting at the Centers for Disease Control and Prevention.
www.scrippsnews.com
August 12, 2025 at 4:48 AM
1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
j'adore Genève
August 7, 2025 at 1:52 PM
j'adore Genève