Cristian Pattaro
@cpattaro.bsky.social
Biostatistics. Genetics. Epidemiology.
Group leader of Biostats & Epi @ Eurac Research
https://cristianpattaro.quarto.pub/cp/
Group leader of Biostats & Epi @ Eurac Research
https://cristianpattaro.quarto.pub/cp/
Reposted by Cristian Pattaro
Incredibly important story that everyone should read.
These are not disorganized lone actors, but well-funded and powerful networks to be treated as serious threats.
They are using our work to push a eugenicist and racist agenda that is scientifically invalid and morally reprehensible.
These are not disorganized lone actors, but well-funded and powerful networks to be treated as serious threats.
They are using our work to push a eugenicist and racist agenda that is scientifically invalid and morally reprehensible.
Genetic Data From Over 20,000 U.S. Children Misused for ‘Race Science’
www.nytimes.com
January 24, 2026 at 5:05 PM
Incredibly important story that everyone should read.
These are not disorganized lone actors, but well-funded and powerful networks to be treated as serious threats.
They are using our work to push a eugenicist and racist agenda that is scientifically invalid and morally reprehensible.
These are not disorganized lone actors, but well-funded and powerful networks to be treated as serious threats.
They are using our work to push a eugenicist and racist agenda that is scientifically invalid and morally reprehensible.
Reposted by Cristian Pattaro
We’re recruiting a data science programme lead to help develop and deliver a bold data science and AI strategy that will position us at the forefront of innovation.
For the full job description and to apply, click here: https://bit.ly/4rrsEKL
For the full job description and to apply, click here: https://bit.ly/4rrsEKL
January 23, 2026 at 3:57 PM
We’re recruiting a data science programme lead to help develop and deliver a bold data science and AI strategy that will position us at the forefront of innovation.
For the full job description and to apply, click here: https://bit.ly/4rrsEKL
For the full job description and to apply, click here: https://bit.ly/4rrsEKL
Reposted by Cristian Pattaro
This looks interesting: Rscript -> .qmd
New CRAN package quartify with initial version 1.1.1
#rstats
https://cran.r-project.org/package=quartify
#rstats
https://cran.r-project.org/package=quartify
CRAN: Package quartify
Converts R scripts (.R) into 'Quarto' markdown documents (.qmd) with automatic formatting. Recognizes 'RStudio' code sections, preserves comments as narrative text, extracts metadata from special comments, and provides both programmatic functions and an interactive 'RStudio' add-in for easy conversion.
cran.r-project.org
January 22, 2026 at 2:44 AM
This looks interesting: Rscript -> .qmd
Reposted by Cristian Pattaro
Tutorial in Biostatistics
Mendelian Randomization Methods for Causal Inference: Estimands, Identification and Inference. Minhao Yao, Anqi Wang, Xihao Li, Zhonghua Liu. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
Mendelian Randomization Methods for Causal Inference: Estimands, Identification and Inference. Minhao Yao, Anqi Wang, Xihao Li, Zhonghua Liu. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
Mendelian Randomization Methods for Causal Inference: Estimands, Identification and Inference
Mendelian randomization (MR) has become an essential tool for causal inference in biomedical and public health research. By using genetic variants as instrumental variables, MR helps address unmeasur...
onlinelibrary.wiley.com
January 23, 2026 at 2:02 PM
Tutorial in Biostatistics
Mendelian Randomization Methods for Causal Inference: Estimands, Identification and Inference. Minhao Yao, Anqi Wang, Xihao Li, Zhonghua Liu. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
Mendelian Randomization Methods for Causal Inference: Estimands, Identification and Inference. Minhao Yao, Anqi Wang, Xihao Li, Zhonghua Liu. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Cristian Pattaro
The Methods Series @ki.se is back!
@epiellie.bsky.social kicks off the 2026 speaker lineup next Tuesday, "How do we actually draw a causal graph? A proposal for evidence-based best practices."
📆 Jan 27, 2026
⏰ 15.00 CET/9.00 EST
📍 Online
Register to attend 👇
stats.sender.net/forms/e7JD1d...
@epiellie.bsky.social kicks off the 2026 speaker lineup next Tuesday, "How do we actually draw a causal graph? A proposal for evidence-based best practices."
📆 Jan 27, 2026
⏰ 15.00 CET/9.00 EST
📍 Online
Register to attend 👇
stats.sender.net/forms/e7JD1d...
January 22, 2026 at 4:25 PM
The Methods Series @ki.se is back!
@epiellie.bsky.social kicks off the 2026 speaker lineup next Tuesday, "How do we actually draw a causal graph? A proposal for evidence-based best practices."
📆 Jan 27, 2026
⏰ 15.00 CET/9.00 EST
📍 Online
Register to attend 👇
stats.sender.net/forms/e7JD1d...
@epiellie.bsky.social kicks off the 2026 speaker lineup next Tuesday, "How do we actually draw a causal graph? A proposal for evidence-based best practices."
📆 Jan 27, 2026
⏰ 15.00 CET/9.00 EST
📍 Online
Register to attend 👇
stats.sender.net/forms/e7JD1d...
Reposted by Cristian Pattaro
📣 🧬🦠 New article out on genetic susceptibility to infection with Omicron variants of SARS-CoV-2. In this international GWAS meta-analysis, we identified loci not found for earlier variants of the virus. The findings point to a central role of glycosylation.
👇
www.nature.com/articles/s41...
👇
www.nature.com/articles/s41...
Central role of glycosylation processes in human genetic susceptibility to SARS-CoV-2 infections with Omicron variants - Nature Genetics
Genome-wide analyses identify 13 loci associated with susceptibility to infection with SARS-CoV-2 Omicron variants, including variation in ST6GAL1, previously associated with influenza susceptibility,...
www.nature.com
January 22, 2026 at 10:39 AM
📣 🧬🦠 New article out on genetic susceptibility to infection with Omicron variants of SARS-CoV-2. In this international GWAS meta-analysis, we identified loci not found for earlier variants of the virus. The findings point to a central role of glycosylation.
👇
www.nature.com/articles/s41...
👇
www.nature.com/articles/s41...
Reposted by Cristian Pattaro
Really honored that our kidney volume genetics paper is accompanied by an editorial commentary in the Feb issue of @kidneyint.bsky.social. Many thanks to @cpattaro.bsky.social & Belen Ponte for the thoughtful perspective, and to all collaborators who made this work possible
#CKD #DeepLearning #GWAS
#CKD #DeepLearning #GWAS
In the new issue of @kidneyint.bsky.social you can find a little commentary that I had the pleasure to coauthor with Belen Ponte: "Genomics of kidney volumes: one size does not fit all"
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Genomics of kidney volumes: one size does not fit all
To characterize the genetic basis of chronic kidney disease, genome-wide association studies focused on chronic kidney disease–defining traits that we…
www.sciencedirect.com
January 22, 2026 at 10:49 AM
Really honored that our kidney volume genetics paper is accompanied by an editorial commentary in the Feb issue of @kidneyint.bsky.social. Many thanks to @cpattaro.bsky.social & Belen Ponte for the thoughtful perspective, and to all collaborators who made this work possible
#CKD #DeepLearning #GWAS
#CKD #DeepLearning #GWAS
In the new issue of @kidneyint.bsky.social you can find a little commentary that I had the pleasure to coauthor with Belen Ponte: "Genomics of kidney volumes: one size does not fit all"
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Genomics of kidney volumes: one size does not fit all
To characterize the genetic basis of chronic kidney disease, genome-wide association studies focused on chronic kidney disease–defining traits that we…
www.sciencedirect.com
January 21, 2026 at 9:12 PM
In the new issue of @kidneyint.bsky.social you can find a little commentary that I had the pleasure to coauthor with Belen Ponte: "Genomics of kidney volumes: one size does not fit all"
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
to him we probably owe the first definition of uniform distribution
#statssky
#statssky
Although William Playfair (1759-1824) is credited with developing the bar chart, in the 1300s Nicole Oresme developed "proto" bar chart diagrams to explain velocity. He also developed the idea of incommensurate fractions & made probabilistic statistical arguments about their relative frequency
January 21, 2026 at 3:35 PM
to him we probably owe the first definition of uniform distribution
#statssky
#statssky
Reposted by Cristian Pattaro
🚀 Introducing the "HT Seminars: Connecting Discoveries"! A new series bringing leading international researchers to Milan to explore what’s next in life sciences. Across disciplines, perspectives and technologies.
Calendar & Registrations 👉 humantechnopole.it/en/training/... #HTseminars
Calendar & Registrations 👉 humantechnopole.it/en/training/... #HTseminars
January 19, 2026 at 4:36 PM
🚀 Introducing the "HT Seminars: Connecting Discoveries"! A new series bringing leading international researchers to Milan to explore what’s next in life sciences. Across disciplines, perspectives and technologies.
Calendar & Registrations 👉 humantechnopole.it/en/training/... #HTseminars
Calendar & Registrations 👉 humantechnopole.it/en/training/... #HTseminars
Reposted by Cristian Pattaro
New paper "Variant selection to maximize variance explained in cis-Mendelian randomization" led by @AngZhou3 and published at @HGGAdvances: pubmed.ncbi.nlm.nih.gov/41548043/, with contribution from @vkarhune.bsky.social, Haodong, Janne, Ash, and Eric. Brief thread:
Variant selection to maximize variance explained in cis-Mendelian randomization - PubMed
Optimal selection of instrumental variables (IVs) from a single gene region in cis-Mendelian randomization is challenging as variants are highly correlated due to linkage disequilibrium (LD). Using only the lead variant is convenient but may not achieve full statistical power if multiple signals exi …
pubmed.ncbi.nlm.nih.gov
January 19, 2026 at 12:24 PM
New paper "Variant selection to maximize variance explained in cis-Mendelian randomization" led by @AngZhou3 and published at @HGGAdvances: pubmed.ncbi.nlm.nih.gov/41548043/, with contribution from @vkarhune.bsky.social, Haodong, Janne, Ash, and Eric. Brief thread:
Causal Genotype–Phenotype Relationships from Population-Sampled Parent–Child Trios: TMT and TDT
onlinelibrary.wiley.com/doi/10.1002/...
#statgen
onlinelibrary.wiley.com/doi/10.1002/...
#statgen
onlinelibrary.wiley.com
January 19, 2026 at 1:55 PM
Causal Genotype–Phenotype Relationships from Population-Sampled Parent–Child Trios: TMT and TDT
onlinelibrary.wiley.com/doi/10.1002/...
#statgen
onlinelibrary.wiley.com/doi/10.1002/...
#statgen
Reposted by Cristian Pattaro
Just finished reading 'Epidemiology: An Introduction' (3rd ed.) by KJ Rothman, KF Huybrechts and EJ Murray (@epiellie.bsky.social). What an excellent book. I especially loved those little boxes explaining, for instance, why p-values in the Table 1 of RCTs make no sense.
Congrats for the great work!
Congrats for the great work!
January 17, 2026 at 1:45 PM
Just finished reading 'Epidemiology: An Introduction' (3rd ed.) by KJ Rothman, KF Huybrechts and EJ Murray (@epiellie.bsky.social). What an excellent book. I especially loved those little boxes explaining, for instance, why p-values in the Table 1 of RCTs make no sense.
Congrats for the great work!
Congrats for the great work!
Reposted by Cristian Pattaro
Reports said the trial was halted. HHS says it will proceed. The revised protocol remains unethical. Scrutiny must continue until participants are no longer placed in harm’s way. I read the revised protocol and wrote a follow-up.
bktitanji.substack.com/p/lipstick-o...
bktitanji.substack.com/p/lipstick-o...
Lipstick on a Pig: Why the Amended Hepatitis B Birth-Dose Trial in Guinea Bissau Remains Ethically Indefensible
How Scrutiny and African Leadership Changed the Conversation
bktitanji.substack.com
January 16, 2026 at 7:18 PM
Reports said the trial was halted. HHS says it will proceed. The revised protocol remains unethical. Scrutiny must continue until participants are no longer placed in harm’s way. I read the revised protocol and wrote a follow-up.
bktitanji.substack.com/p/lipstick-o...
bktitanji.substack.com/p/lipstick-o...
Very proud that Eurac Research has joined the Scholars at Risk network!
www.scholarsatrisk.org
#EuracResearch
www.scholarsatrisk.org
#EuracResearch
Scholars at Risk | Protecting scholars and the freedom to think, question, and share ideas
www.scholarsatrisk.org
January 16, 2026 at 10:49 AM
Very proud that Eurac Research has joined the Scholars at Risk network!
www.scholarsatrisk.org
#EuracResearch
www.scholarsatrisk.org
#EuracResearch
Reposted by Cristian Pattaro
Excited to share our new preprint from the @arbelharpak.bsky.social Lab!
How do recruitment into genetic studies and study characteristics impact what we infer about the genetic bases of traits, and what are the consequences? (1/21)
www.biorxiv.org/content/10.6...
How do recruitment into genetic studies and study characteristics impact what we infer about the genetic bases of traits, and what are the consequences? (1/21)
www.biorxiv.org/content/10.6...
Representation in genetic studies affects inference about genetic architecture
Knowledge of a trait's "genetic architecture," namely the joint distribution of allele frequencies of causal variants and the direction and magnitude of their effects, is essential to understanding it...
www.biorxiv.org
January 14, 2026 at 7:07 PM
Excited to share our new preprint from the @arbelharpak.bsky.social Lab!
How do recruitment into genetic studies and study characteristics impact what we infer about the genetic bases of traits, and what are the consequences? (1/21)
www.biorxiv.org/content/10.6...
How do recruitment into genetic studies and study characteristics impact what we infer about the genetic bases of traits, and what are the consequences? (1/21)
www.biorxiv.org/content/10.6...
Good intentions for 2026: new website! Let's see for how long I could keep it up to date 😅
cristianpattaro.quarto.pub/cp/
cristianpattaro.quarto.pub/cp/
Cristian Pattaro
cristianpattaro.quarto.pub
January 14, 2026 at 10:37 PM
Good intentions for 2026: new website! Let's see for how long I could keep it up to date 😅
cristianpattaro.quarto.pub/cp/
cristianpattaro.quarto.pub/cp/
Reposted by Cristian Pattaro
If you are interested in the past, present, and future of Mendelian Randomisation, join us later this month for a Causal Inference Interest Group seminar on MR with none other than @mendelrandom.bsky.social
Zoom registration link: ucl.zoom.us/meeting/regi...
Zoom registration link: ucl.zoom.us/meeting/regi...
January 5, 2026 at 7:00 PM
If you are interested in the past, present, and future of Mendelian Randomisation, join us later this month for a Causal Inference Interest Group seminar on MR with none other than @mendelrandom.bsky.social
Zoom registration link: ucl.zoom.us/meeting/regi...
Zoom registration link: ucl.zoom.us/meeting/regi...
Reposted by Cristian Pattaro
In 2021 @janewit-thekidgene.bsky.social joined our lab & decided to define the prevalence & clinical correlates of known genetic forms of nephrotic syndrome among an unselected group of adults. 5 yrs later, we're excited to share what he found; a 🧵 kidney-international.org/article/S008...
January 12, 2026 at 8:25 PM
In 2021 @janewit-thekidgene.bsky.social joined our lab & decided to define the prevalence & clinical correlates of known genetic forms of nephrotic syndrome among an unselected group of adults. 5 yrs later, we're excited to share what he found; a 🧵 kidney-international.org/article/S008...
scientific integrity - leading by example 👏
Errare humanum est ...
(To err is human ...)
While preparing my PhD thesis, I discovered some (minor) errors in which trials and meta-analyses were included for analysis in our meta-epidemiological study.
1/5
(To err is human ...)
While preparing my PhD thesis, I discovered some (minor) errors in which trials and meta-analyses were included for analysis in our meta-epidemiological study.
1/5
Corrigendum to “Impact of active placebo controls on estimated drug effects in randomized trials: a meta-epidemiological study” [Journal of Clinical Epidemiology 188 (2025) 111998] - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
January 12, 2026 at 4:25 PM
scientific integrity - leading by example 👏
Reposted by Cristian Pattaro
👀 New blog post! 👀
Ever made a *spaghetti* line chart and wondered how you can make it more accessible and more aesthetically pleasing at the same time? 📈
Read this blog post: nrennie.rbind.io/blog/accessi...
#DataViz #RStats
Ever made a *spaghetti* line chart and wondered how you can make it more accessible and more aesthetically pleasing at the same time? 📈
Read this blog post: nrennie.rbind.io/blog/accessi...
#DataViz #RStats
How to create a more accessible line chart – Nicola Rennie
The default settings for chart software are not guaranteed to be accessible, and often need to be adapted for your own chart. In this blog post, we’ll transform a line chart to make it more accessible...
nrennie.rbind.io
January 12, 2026 at 9:59 AM
👀 New blog post! 👀
Ever made a *spaghetti* line chart and wondered how you can make it more accessible and more aesthetically pleasing at the same time? 📈
Read this blog post: nrennie.rbind.io/blog/accessi...
#DataViz #RStats
Ever made a *spaghetti* line chart and wondered how you can make it more accessible and more aesthetically pleasing at the same time? 📈
Read this blog post: nrennie.rbind.io/blog/accessi...
#DataViz #RStats
Our paper on the Expanded Registry of candidate cis-Regulatory Elements (cCREs) is out 🎉
www.nature.com/articles/s41...
To celebrate, here’s a "meme-torial" walkthrough of the science.
Let’s get started 🧵 1/11
www.nature.com/articles/s41...
To celebrate, here’s a "meme-torial" walkthrough of the science.
Let’s get started 🧵 1/11
a man wearing a plaid shirt and a purple hat is saying here we go .
ALT: a man wearing a plaid shirt and a purple hat is saying here we go .
media.tenor.com
January 8, 2026 at 8:04 AM
Reposted by Cristian Pattaro
If you like larger sample sizes, then do check out our reprocessed and fine mapped cis-eQTLs and cis-sQTLs (leafCutter and MAJIQ!) from the INTERVAL cohort (whole blood, n up to 4,729)!
zenodo.org/records/1795...
These will be on the eQTL Catalogue FTP soon as well.
cc @yosephbarash.bsky.social
zenodo.org/records/1795...
These will be on the eQTL Catalogue FTP soon as well.
cc @yosephbarash.bsky.social
Fine mapped eQTL and sQTL summary statistics from the INTERVAL RNA-seq study (part 1)
This repository contains fine mapped eQTL and sQTL summary statistics from the INTERVAL RNA-seq study (Tokolyi et al, 2025). Datasets QTD001000-QTD001002 are based on the whole cohort of 4,729 samples...
zenodo.org
January 7, 2026 at 10:24 AM
If you like larger sample sizes, then do check out our reprocessed and fine mapped cis-eQTLs and cis-sQTLs (leafCutter and MAJIQ!) from the INTERVAL cohort (whole blood, n up to 4,729)!
zenodo.org/records/1795...
These will be on the eQTL Catalogue FTP soon as well.
cc @yosephbarash.bsky.social
zenodo.org/records/1795...
These will be on the eQTL Catalogue FTP soon as well.
cc @yosephbarash.bsky.social
Reposted by Cristian Pattaro
In Memoriam: The Academic Journal
arxiv.org
January 6, 2026 at 12:12 PM
Reposted by Cristian Pattaro
reposting for the Monday crowd—
This week in my newsletter I discussed the “Have your best baby” campaign by Nucleus Genomics as an example of what @gaiaghirardi.bsky.social and @arnovanhootegem.bsky.social have called “commodification on steroids”
open.substack.com/pub/kathrynp...
This week in my newsletter I discussed the “Have your best baby” campaign by Nucleus Genomics as an example of what @gaiaghirardi.bsky.social and @arnovanhootegem.bsky.social have called “commodification on steroids”
open.substack.com/pub/kathrynp...
January 5, 2026 at 2:28 PM
reposting for the Monday crowd—
This week in my newsletter I discussed the “Have your best baby” campaign by Nucleus Genomics as an example of what @gaiaghirardi.bsky.social and @arnovanhootegem.bsky.social have called “commodification on steroids”
open.substack.com/pub/kathrynp...
This week in my newsletter I discussed the “Have your best baby” campaign by Nucleus Genomics as an example of what @gaiaghirardi.bsky.social and @arnovanhootegem.bsky.social have called “commodification on steroids”
open.substack.com/pub/kathrynp...