Ben Steventon
@bensteventon.bsky.social
Pinned
Check out this work from @gserranonajera.bsky.social and Apolline Delahaye! They show how gastruloids can employ different morphogenetic strategies to set up a body axis. It nicely builds from Guillermo’s PhD work recapitulating gastrulation modes in the chick: www.science.org/doi/10.1126/...
Reposted by Ben Steventon
We have a new lab photo. Busy times in the Delas Lab!
Last month Maria and Shaun joined us to start their PhDs.
Learn more about our research and our team: delaslab.com
We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.
Last month Maria and Shaun joined us to start their PhDs.
Learn more about our research and our team: delaslab.com
We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.
November 12, 2025 at 2:04 PM
We have a new lab photo. Busy times in the Delas Lab!
Last month Maria and Shaun joined us to start their PhDs.
Learn more about our research and our team: delaslab.com
We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.
Last month Maria and Shaun joined us to start their PhDs.
Learn more about our research and our team: delaslab.com
We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.
Reposted by Ben Steventon
This was such a fun conversation. Thank you for having me.
We're very excited to welcome Dr. @sumrubayin.bsky.social from the @gurdoninstitute.bsky.social onto the next episode of the podcast! 🎉
Her lab studies the mouse #cerebellum to better understand the regulation of #neural stem cell behavior. 🧠
Her lab studies the mouse #cerebellum to better understand the regulation of #neural stem cell behavior. 🧠
November 11, 2025 at 10:51 AM
This was such a fun conversation. Thank you for having me.
Reposted by Ben Steventon
New preprint led by the brilliant @aleksandra-marconi.bsky.social on cichlid brain diversification, fgf8a signalling and regulatory divergence with TEs on the mix! All part of a wonderful collaboration with @ebablab.bsky.social
www.biorxiv.org/content/10.1...
@camzoology.bsky.social
www.biorxiv.org/content/10.1...
@camzoology.bsky.social
October 24, 2025 at 8:45 PM
New preprint led by the brilliant @aleksandra-marconi.bsky.social on cichlid brain diversification, fgf8a signalling and regulatory divergence with TEs on the mix! All part of a wonderful collaboration with @ebablab.bsky.social
www.biorxiv.org/content/10.1...
@camzoology.bsky.social
www.biorxiv.org/content/10.1...
@camzoology.bsky.social
Reposted by Ben Steventon
Thrilled to see this published!
Well done Ahmed on spearheading a project revealing mitotic errors in human embryos arise much later than anticipated.
Thank you to collaborators @bensteventon.bsky.social Leila Muresan and all of the wonderful teams at Bourn Hall and Create Fertility clinics!
Well done Ahmed on spearheading a project revealing mitotic errors in human embryos arise much later than anticipated.
Thank you to collaborators @bensteventon.bsky.social Leila Muresan and all of the wonderful teams at Bourn Hall and Create Fertility clinics!
Live imaging of late-stage preimplantation human embryos reveals de novo mitotic errors - @niakanlab.bsky.social @loke-ctr.bsky.social go.nature.com/3JdRdu8
Live imaging of late-stage preimplantation human embryos reveals de novo mitotic errors - Nature Biotechnology
A method to label cultured human embryos finds chromosome segregation errors in placenta-fated cells.
go.nature.com
October 23, 2025 at 8:13 PM
Thrilled to see this published!
Well done Ahmed on spearheading a project revealing mitotic errors in human embryos arise much later than anticipated.
Thank you to collaborators @bensteventon.bsky.social Leila Muresan and all of the wonderful teams at Bourn Hall and Create Fertility clinics!
Well done Ahmed on spearheading a project revealing mitotic errors in human embryos arise much later than anticipated.
Thank you to collaborators @bensteventon.bsky.social Leila Muresan and all of the wonderful teams at Bourn Hall and Create Fertility clinics!
Reposted by Ben Steventon
This is an excellent news and views article from Corentin Mollier & Jean-Léon Maître @maitrejl.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Long-term imaging of cell divisions in human preimplantation embryos - Nature Biotechnology
An optimized approach for live imaging of human embryos enables visualization of mitotic errors during blastocyst development.
www.nature.com
October 23, 2025 at 8:17 PM
This is an excellent news and views article from Corentin Mollier & Jean-Léon Maître @maitrejl.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Congratulations Ahmed and colleagues in the @niakanlab.bsky.social on this beautiful work tracking mitotic errors by live imaging the human embryos!
Thrilled to see this published!
Well done Ahmed on spearheading a project revealing mitotic errors in human embryos arise much later than anticipated.
Thank you to collaborators @bensteventon.bsky.social Leila Muresan and all of the wonderful teams at Bourn Hall and Create Fertility clinics!
Well done Ahmed on spearheading a project revealing mitotic errors in human embryos arise much later than anticipated.
Thank you to collaborators @bensteventon.bsky.social Leila Muresan and all of the wonderful teams at Bourn Hall and Create Fertility clinics!
Live imaging of late-stage preimplantation human embryos reveals de novo mitotic errors - @niakanlab.bsky.social @loke-ctr.bsky.social go.nature.com/3JdRdu8
October 23, 2025 at 9:15 PM
Congratulations Ahmed and colleagues in the @niakanlab.bsky.social on this beautiful work tracking mitotic errors by live imaging the human embryos!
Reposted by Ben Steventon
In this review @Andrea-Loreto.bsky.social and I discuss the breadth of therapeutic potential for the neurodegenerative enzyme SARM1
- Challenges for SARM1 therapeutic inhibition
- SARM1 in non-neuronal cells
- SARM1 activation for selective peripheral neuroablation.
www.cell.com/trends/pharm...
- Challenges for SARM1 therapeutic inhibition
- SARM1 in non-neuronal cells
- SARM1 activation for selective peripheral neuroablation.
www.cell.com/trends/pharm...
Targeting SARM1: from inhibition for neuroprotection to activation for neuroablation
Sterile alpha and TIR motif-containing protein 1 (SARM1),is a central enzyme that
drives programmed axon degeneration and has gathered significant interest as a therapeutic
target. Despite preclinical...
www.cell.com
October 21, 2025 at 6:16 AM
In this review @Andrea-Loreto.bsky.social and I discuss the breadth of therapeutic potential for the neurodegenerative enzyme SARM1
- Challenges for SARM1 therapeutic inhibition
- SARM1 in non-neuronal cells
- SARM1 activation for selective peripheral neuroablation.
www.cell.com/trends/pharm...
- Challenges for SARM1 therapeutic inhibition
- SARM1 in non-neuronal cells
- SARM1 activation for selective peripheral neuroablation.
www.cell.com/trends/pharm...
Reposted by Ben Steventon
Planarian #NuRD Alert!
"the NuRD complex may drive differentiation into somatic lineages in planarians"
Yeah it does. #NuRDIsTheWormyWord
#Chromatin #Transcription
doi.org/10.3389/frag...
"the NuRD complex may drive differentiation into somatic lineages in planarians"
Yeah it does. #NuRDIsTheWormyWord
#Chromatin #Transcription
doi.org/10.3389/frag...
Frontiers | Systemic identification and characterization of the conserved core NuRD complex in planarian
The nucleosome remodeling and deacetylase (NuRD) complex, well known for its ATP-dependent chromatin remodeling and histone deacetylation activities combined...
doi.org
October 17, 2025 at 9:06 AM
Planarian #NuRD Alert!
"the NuRD complex may drive differentiation into somatic lineages in planarians"
Yeah it does. #NuRDIsTheWormyWord
#Chromatin #Transcription
doi.org/10.3389/frag...
"the NuRD complex may drive differentiation into somatic lineages in planarians"
Yeah it does. #NuRDIsTheWormyWord
#Chromatin #Transcription
doi.org/10.3389/frag...
Reposted by Ben Steventon
Looking for an interesting interdisciplinary PhD on spinal cord regeneration? Join us to explore how tissues rebuild after injury — combining biology, physics, and computational approaches!
PIs: Karel Dorey, @ramandas.bsky.social, and @osvaldo-chara.bsky.social.
👉: www.findaphd.com/phds/project...
PIs: Karel Dorey, @ramandas.bsky.social, and @osvaldo-chara.bsky.social.
👉: www.findaphd.com/phds/project...
(Bicentenary) Applying a multidisciplinary approach to uncover the mechanisms underpinning successful regeneration of the spinal cord after injury at The University of Manchester on FindAPhD.com
PhD Project - (Bicentenary) Applying a multidisciplinary approach to uncover the mechanisms underpinning successful regeneration of the spinal cord after injury at The University of Manchester, listed...
www.findaphd.com
October 15, 2025 at 1:28 PM
Looking for an interesting interdisciplinary PhD on spinal cord regeneration? Join us to explore how tissues rebuild after injury — combining biology, physics, and computational approaches!
PIs: Karel Dorey, @ramandas.bsky.social, and @osvaldo-chara.bsky.social.
👉: www.findaphd.com/phds/project...
PIs: Karel Dorey, @ramandas.bsky.social, and @osvaldo-chara.bsky.social.
👉: www.findaphd.com/phds/project...
Reposted by Ben Steventon
Next Monday 20th October, we’re delighted to welcome
@pflenne.bsky.social for a talk co-hosted with @tlmcambridge.bsky.social. For further information and updates, please visit our website!
ucammorphogenesisseries.com
@pflenne.bsky.social for a talk co-hosted with @tlmcambridge.bsky.social. For further information and updates, please visit our website!
ucammorphogenesisseries.com
October 16, 2025 at 1:08 PM
Next Monday 20th October, we’re delighted to welcome
@pflenne.bsky.social for a talk co-hosted with @tlmcambridge.bsky.social. For further information and updates, please visit our website!
ucammorphogenesisseries.com
@pflenne.bsky.social for a talk co-hosted with @tlmcambridge.bsky.social. For further information and updates, please visit our website!
ucammorphogenesisseries.com
Reposted by Ben Steventon
Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...
October 11, 2025 at 8:22 AM
Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...
Reposted by Ben Steventon
#DBfeature
Research facilities in the UK, France, and Japan maintaining transgenic lines for Avian developmental biology
By Lindsay Henderson, Yuya Okuzaki, Christophe Marcelle, Mike McGrew, and Ken-ichi Nishijima
tinyurl.com/4drw4d6a
#SpecialIssue on Avian model systems
Research facilities in the UK, France, and Japan maintaining transgenic lines for Avian developmental biology
By Lindsay Henderson, Yuya Okuzaki, Christophe Marcelle, Mike McGrew, and Ken-ichi Nishijima
tinyurl.com/4drw4d6a
#SpecialIssue on Avian model systems
October 10, 2025 at 11:54 AM
#DBfeature
Research facilities in the UK, France, and Japan maintaining transgenic lines for Avian developmental biology
By Lindsay Henderson, Yuya Okuzaki, Christophe Marcelle, Mike McGrew, and Ken-ichi Nishijima
tinyurl.com/4drw4d6a
#SpecialIssue on Avian model systems
Research facilities in the UK, France, and Japan maintaining transgenic lines for Avian developmental biology
By Lindsay Henderson, Yuya Okuzaki, Christophe Marcelle, Mike McGrew, and Ken-ichi Nishijima
tinyurl.com/4drw4d6a
#SpecialIssue on Avian model systems
Reposted by Ben Steventon
I wrote something on developmental biology and disability and put it up on the node last night:
thenode.biologists.com/developmenta...
I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!
thenode.biologists.com/developmenta...
I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!
Developmental Biology and Disability - the Node
Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.
thenode.biologists.com
September 30, 2025 at 9:38 AM
I wrote something on developmental biology and disability and put it up on the node last night:
thenode.biologists.com/developmenta...
I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!
thenode.biologists.com/developmenta...
I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!
Reposted by Ben Steventon
🚨 Excited to introduce FuChi (Fucci chicken), the first avian cell cycle reporter line. Thank you to all those who contributed to putting this paper together. I really think it showcases the power and beauty of the chick embryo as a developmental biology model. 🐥 🥚 🔬 @roslininstitute.bsky.social
September 26, 2025 at 6:00 AM
🚨 Excited to introduce FuChi (Fucci chicken), the first avian cell cycle reporter line. Thank you to all those who contributed to putting this paper together. I really think it showcases the power and beauty of the chick embryo as a developmental biology model. 🐥 🥚 🔬 @roslininstitute.bsky.social
Reposted by Ben Steventon
FuChi: A cell cycle biosensor for investigating cell-cycle kinetics during avian development. https://www.biorxiv.org/content/10.1101/2025.09.24.678103v1
September 26, 2025 at 4:30 AM
FuChi: A cell cycle biosensor for investigating cell-cycle kinetics during avian development. https://www.biorxiv.org/content/10.1101/2025.09.24.678103v1
Reposted by Ben Steventon
Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!
September 23, 2025 at 7:39 PM
Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!
Reposted by Ben Steventon
Great to see this from @vmetzis.bsky.social & co published
Dissection of CDX2 regulatory elements identifies a repressive element that converts to an enhancer with a nuclear receptor motif switch
www.cell.com/developmenta...
Dissection of CDX2 regulatory elements identifies a repressive element that converts to an enhancer with a nuclear receptor motif switch
www.cell.com/developmenta...
A dual enhancer-attenuator element ensures transient Cdx2 expression during mouse posterior body formation
Amblard et al. dissect the function of cis-regulatory elements regulating transient
Cdx2 expression during mouse caudal body formation. They highlight the requirement
of an attenuator, a transiently r...
www.cell.com
September 22, 2025 at 3:34 PM
Great to see this from @vmetzis.bsky.social & co published
Dissection of CDX2 regulatory elements identifies a repressive element that converts to an enhancer with a nuclear receptor motif switch
www.cell.com/developmenta...
Dissection of CDX2 regulatory elements identifies a repressive element that converts to an enhancer with a nuclear receptor motif switch
www.cell.com/developmenta...
Reposted by Ben Steventon
🚨 The International Developmental Mechanics Zoom Seminar Series is back on Sept 25!
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
September 16, 2025 at 6:08 PM
🚨 The International Developmental Mechanics Zoom Seminar Series is back on Sept 25!
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
🎤 We have an exciting line-up of speakers this fall. See the image below for details
🌐 Website: sites.google.com/view/devmech...
📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv
Reposted by Ben Steventon
The Company of Biologists and the British Society for Developmental Biology: a model partnership
As part of the #biologists100 anniversary, Saanjbati Adhikari and Raman Das review the relationship between @biologists.bsky.social and @bsdb.bsky.social
doi.org/10.1242/dev....
As part of the #biologists100 anniversary, Saanjbati Adhikari and Raman Das review the relationship between @biologists.bsky.social and @bsdb.bsky.social
doi.org/10.1242/dev....
September 15, 2025 at 3:49 PM
The Company of Biologists and the British Society for Developmental Biology: a model partnership
As part of the #biologists100 anniversary, Saanjbati Adhikari and Raman Das review the relationship between @biologists.bsky.social and @bsdb.bsky.social
doi.org/10.1242/dev....
As part of the #biologists100 anniversary, Saanjbati Adhikari and Raman Das review the relationship between @biologists.bsky.social and @bsdb.bsky.social
doi.org/10.1242/dev....
Reposted by Ben Steventon
New article out now!
Our researchers @sumrubayin.bsky.social, @bensteventon.bsky.social, and @storerlab.bsky.social share key takeaways from a workshop on complex tissue regeneration, highlighting the need for more collaboration and interdisciplinary work.
➡️ journals.biologists.com/dev/article/...
Our researchers @sumrubayin.bsky.social, @bensteventon.bsky.social, and @storerlab.bsky.social share key takeaways from a workshop on complex tissue regeneration, highlighting the need for more collaboration and interdisciplinary work.
➡️ journals.biologists.com/dev/article/...
Building and rebuilding complex tissues: strategic visions from a research-led workshop
ABSTRACT. How complex tissues develop and regenerate post-injury is one of the most fascinating and important processes in biology. Recent technical advances that enable the generation of a quantitati...
journals.biologists.com
September 4, 2025 at 2:10 PM
New article out now!
Our researchers @sumrubayin.bsky.social, @bensteventon.bsky.social, and @storerlab.bsky.social share key takeaways from a workshop on complex tissue regeneration, highlighting the need for more collaboration and interdisciplinary work.
➡️ journals.biologists.com/dev/article/...
Our researchers @sumrubayin.bsky.social, @bensteventon.bsky.social, and @storerlab.bsky.social share key takeaways from a workshop on complex tissue regeneration, highlighting the need for more collaboration and interdisciplinary work.
➡️ journals.biologists.com/dev/article/...
Reposted by Ben Steventon
We have a fully funded 3y postdoc position open!!!! Come join us @mpi-cbg.de and @poldresden.bsky.social to understand the role of Membranes in Controlling Biogenic Crystallization :) this is part of our #HFSP funded project with @noemijimenezrojo.bsky.social and @vmonje.bsky.social! Applications👇
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...
September 1, 2025 at 9:17 PM
We have a fully funded 3y postdoc position open!!!! Come join us @mpi-cbg.de and @poldresden.bsky.social to understand the role of Membranes in Controlling Biogenic Crystallization :) this is part of our #HFSP funded project with @noemijimenezrojo.bsky.social and @vmonje.bsky.social! Applications👇
Reposted by Ben Steventon
Lovely piece on five model organisms for the origin of animal multicellularity and on the community who studies them. It was a pleasure to make a small contribution.
For some three billion years, unicellular organisms ruled Earth. Then, around one billion years ago, a new chapter of life began
go.nature.com/3JyRV4S
go.nature.com/3JyRV4S
How did life get multicellular? Five simple organisms could have the answer
Single-celled species that often stick together in colonies have researchers rethinking the origin of animals.
go.nature.com
August 27, 2025 at 5:14 PM
Lovely piece on five model organisms for the origin of animal multicellularity and on the community who studies them. It was a pleasure to make a small contribution.
Reposted by Ben Steventon
Excited to share our recent viewpoint with @storerlab.bsky.social led by Kirsten Sadler, on epigenetic mechanisms of regenerative resilience.
Ageing versus developmental silencing: Answers from the epigenome - Sadler - The FEBS Journal - febs.onlinelibrary.wiley.com/doi/10.1111/...
Ageing versus developmental silencing: Answers from the epigenome - Sadler - The FEBS Journal - febs.onlinelibrary.wiley.com/doi/10.1111/...
FEBS Press
It is easier for young animals to regenerate damaged or missing tissues. In this Viewpoint, we propose that this is, in part, attributed to epigenetic changes, with chromatin becoming more closed and....
febs.onlinelibrary.wiley.com
August 22, 2025 at 10:06 AM
Excited to share our recent viewpoint with @storerlab.bsky.social led by Kirsten Sadler, on epigenetic mechanisms of regenerative resilience.
Ageing versus developmental silencing: Answers from the epigenome - Sadler - The FEBS Journal - febs.onlinelibrary.wiley.com/doi/10.1111/...
Ageing versus developmental silencing: Answers from the epigenome - Sadler - The FEBS Journal - febs.onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Ben Steventon
#DBfeature 🐣❤️
Automated non-invasive laser speckle imaging of the chick heart rate and extraembryonic blood vessels and their response to Nifedipine and Amlodipine drugs
by Carol Readhead, Simon Mahler et al
www.sciencedirect.com/science/arti...
Automated non-invasive laser speckle imaging of the chick heart rate and extraembryonic blood vessels and their response to Nifedipine and Amlodipine drugs
by Carol Readhead, Simon Mahler et al
www.sciencedirect.com/science/arti...
August 15, 2025 at 1:47 PM
#DBfeature 🐣❤️
Automated non-invasive laser speckle imaging of the chick heart rate and extraembryonic blood vessels and their response to Nifedipine and Amlodipine drugs
by Carol Readhead, Simon Mahler et al
www.sciencedirect.com/science/arti...
Automated non-invasive laser speckle imaging of the chick heart rate and extraembryonic blood vessels and their response to Nifedipine and Amlodipine drugs
by Carol Readhead, Simon Mahler et al
www.sciencedirect.com/science/arti...
Reposted by Ben Steventon
Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️
August 11, 2025 at 1:18 PM
Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️