Joaquina Delas
@joadelas.bsky.social
LMCB Group Leader at UCL. Cis-regulatory control of cell fate choice in development.
https://delaslab.com/
https://delaslab.com/
Pinned
Joaquina Delas
@joadelas.bsky.social
· Mar 11
Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org
Pleased to share our latest work. Extremely fun project with @jamesbriscoe.bsky.social l and @jcornwallscoones.bsky.social y.social
Curious about how cis-regulatory elements encode information? Passionate about patterning (re)engineering? Please read! (🧵 by Jake below)
bsky.app/profile/jcor...
Curious about how cis-regulatory elements encode information? Passionate about patterning (re)engineering? Please read! (🧵 by Jake below)
bsky.app/profile/jcor...
Reposted by Joaquina Delas
OFERTA DE EMPLEO (por favor difundir):
Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas
👇
Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas
👇
November 6, 2025 at 5:24 PM
OFERTA DE EMPLEO (por favor difundir):
Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas
👇
Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas
👇
Go to sleep in London, wake up in Edinburg! Great experience aboard the Caledonian Sleeper train.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
October 30, 2025 at 8:08 AM
Go to sleep in London, wake up in Edinburg! Great experience aboard the Caledonian Sleeper train.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
Reposted by Joaquina Delas
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...
www.biorxiv.org
October 26, 2025 at 5:15 PM
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
Very excited for this Developmental Biology meeting next May. Join us!
I am very excited to announce the opening of the submission site for the upcoming Conférences Jacques Monod on Developmental Biology, May 18-22, 2026 cjm.sb-roscoff.fr/en/conferenc...
@lionlchristiaen.bsky.social and I have an exciting program of speakers and slots for selected short talks, etc.
@lionlchristiaen.bsky.social and I have an exciting program of speakers and slots for selected short talks, etc.
October 25, 2025 at 9:00 PM
Very excited for this Developmental Biology meeting next May. Join us!
Reposted by Joaquina Delas
We hiring! Please share this post with your talented ECRs
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
October 21, 2025 at 3:57 PM
We hiring! Please share this post with your talented ECRs
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
Reposted by Joaquina Delas
Tomorrow wednesday 22nd at 11am, lesson #2 of Neil Shubin, Guest Prof @college-de-france.fr ‘Discovering how fish evolved to walk’. Wonderful first lesson @ www.youtube.com/watch?v=0B6y... Fish friends in Paris, please RT🤘 Swim the Seine till St Michel, then get out and walk left. Free access
October 21, 2025 at 6:46 AM
Tomorrow wednesday 22nd at 11am, lesson #2 of Neil Shubin, Guest Prof @college-de-france.fr ‘Discovering how fish evolved to walk’. Wonderful first lesson @ www.youtube.com/watch?v=0B6y... Fish friends in Paris, please RT🤘 Swim the Seine till St Michel, then get out and walk left. Free access
Reposted by Joaquina Delas
We are looking forward to spending the next two days discussing INTERESTING THINGS at our workshop on Generative Biology: new approaches to study developmental design principles #GenBio25
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
En route to Brighton—for the 1st time—for the @royalsociety.org Generative Biology meeting organised by @jcornwallscoones.bsky.social, @dbenzinger.bsky.social & @cellysally.bsky.social. Happy to chat about @dev-journal.bsky.social, @the-node.bsky.social & @biologists.bsky.social. Also have freebies!
October 19, 2025 at 5:00 PM
We are looking forward to spending the next two days discussing INTERESTING THINGS at our workshop on Generative Biology: new approaches to study developmental design principles #GenBio25
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
Reposted by Joaquina Delas
October 17, 2025 at 9:22 AM
We made it to Gastrulation Reloaded!
We didn’t think we’d be late but we had to go in circles around the block. I would not have thought any other institute would be harder to get into than The Crick!
We didn’t think we’d be late but we had to go in circles around the block. I would not have thought any other institute would be harder to get into than The Crick!
October 14, 2025 at 5:16 PM
We made it to Gastrulation Reloaded!
We didn’t think we’d be late but we had to go in circles around the block. I would not have thought any other institute would be harder to get into than The Crick!
We didn’t think we’d be late but we had to go in circles around the block. I would not have thought any other institute would be harder to get into than The Crick!
Come and be our neighbours!
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 10, 2025 at 4:06 PM
Come and be our neighbours!
Reposted by Joaquina Delas
Lab’s 1st preprint!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 1:26 PM
Lab’s 1st preprint!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.
@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.
He is on the job market!
Reposted by Joaquina Delas
How does life construct itself from within, and how might we learn to emulate its generative logic? Glad to be soon talking and discussing with @philipcball.bsky.social @bertaverd.bsky.social and other great colleagues at this @royalsociety.org event royalsociety.org/science-even...
Generative biology: new approaches to study developmental design principles | Royal Society
Theo Murphy meeting organised by Dr Jake Cornwall-Scoones, Dr Dirk Benzinger, and Professor Sally Lowell.
royalsociety.org
October 8, 2025 at 9:53 PM
How does life construct itself from within, and how might we learn to emulate its generative logic? Glad to be soon talking and discussing with @philipcball.bsky.social @bertaverd.bsky.social and other great colleagues at this @royalsociety.org event royalsociety.org/science-even...
Reposted by Joaquina Delas
Thrilled to share that the lab has been awarded a @wellcometrust.bsky.social Discovery Award to keep exploring the evolution of 6-methyladenine #6mA in Eukaryotes. We'll open postdoc (3️⃣) and tech (1️⃣) positions to start in 2026, please share with candidates or reach out if you’d like to join us.
October 8, 2025 at 12:17 PM
Thrilled to share that the lab has been awarded a @wellcometrust.bsky.social Discovery Award to keep exploring the evolution of 6-methyladenine #6mA in Eukaryotes. We'll open postdoc (3️⃣) and tech (1️⃣) positions to start in 2026, please share with candidates or reach out if you’d like to join us.
Reposted by Joaquina Delas
Reposted by Joaquina Delas
Dr. Sophie Acton (@actonlab.bsky.social/UCL)
is a Cancer Research UK Senior Fellow with an interest in lymphoid tissue biology.
At #KSStromal26, she'll be sharing her insights on podoplanin - a molecule that controls DC motility within the lymph node.
Register now! Link in bio.
is a Cancer Research UK Senior Fellow with an interest in lymphoid tissue biology.
At #KSStromal26, she'll be sharing her insights on podoplanin - a molecule that controls DC motility within the lymph node.
Register now! Link in bio.
September 24, 2025 at 6:37 AM
Dr. Sophie Acton (@actonlab.bsky.social/UCL)
is a Cancer Research UK Senior Fellow with an interest in lymphoid tissue biology.
At #KSStromal26, she'll be sharing her insights on podoplanin - a molecule that controls DC motility within the lymph node.
Register now! Link in bio.
is a Cancer Research UK Senior Fellow with an interest in lymphoid tissue biology.
At #KSStromal26, she'll be sharing her insights on podoplanin - a molecule that controls DC motility within the lymph node.
Register now! Link in bio.
Reposted by Joaquina Delas
Organizing the National Course of Genetics 🧬 by @segenetica.bsky.social and Conexion Genoma @csic.es alongside @dariloops.bsky.social has been a blast!
A great opportunity for young researchers to learn and interact with leaders in the filed of #genomics during a whole week - the future is bright!
A great opportunity for young researchers to learn and interact with leaders in the filed of #genomics during a whole week - the future is bright!
September 19, 2025 at 7:06 PM
Organizing the National Course of Genetics 🧬 by @segenetica.bsky.social and Conexion Genoma @csic.es alongside @dariloops.bsky.social has been a blast!
A great opportunity for young researchers to learn and interact with leaders in the filed of #genomics during a whole week - the future is bright!
A great opportunity for young researchers to learn and interact with leaders in the filed of #genomics during a whole week - the future is bright!
Reposted by Joaquina Delas
🔚Last day of the #CNG2025 by the @segenetica.bsky.social and Conexion Genoma @csic.es
We close our scientific program with talks by @joadelas.bsky.social from UCL on developmental patterning, and Jose Manuel Franco @cnb-csic.bsky.social on transcription factors in plants 🌱
We close our scientific program with talks by @joadelas.bsky.social from UCL on developmental patterning, and Jose Manuel Franco @cnb-csic.bsky.social on transcription factors in plants 🌱
September 19, 2025 at 9:37 AM
🔚Last day of the #CNG2025 by the @segenetica.bsky.social and Conexion Genoma @csic.es
We close our scientific program with talks by @joadelas.bsky.social from UCL on developmental patterning, and Jose Manuel Franco @cnb-csic.bsky.social on transcription factors in plants 🌱
We close our scientific program with talks by @joadelas.bsky.social from UCL on developmental patterning, and Jose Manuel Franco @cnb-csic.bsky.social on transcription factors in plants 🌱
Reposted by Joaquina Delas
Llegamos al último día del curso #CNG2025 con @joadelas.bsky.social @ucl.ac.uk, explorando los patrones espaciales y temporales en el desarrollo!
September 19, 2025 at 7:17 AM
Llegamos al último día del curso #CNG2025 con @joadelas.bsky.social @ucl.ac.uk, explorando los patrones espaciales y temporales en el desarrollo!
Very excited to be on my way to the National Genetics Course in Madrid @segenetica.bsky.social
It is always very special to go back to Spain for scientific reasons. It would be hard to convince uni student Joaquina of what would come.
Impressive (aka intimidating 😂) line up
It is always very special to go back to Spain for scientific reasons. It would be hard to convince uni student Joaquina of what would come.
Impressive (aka intimidating 😂) line up
September 17, 2025 at 6:19 AM
Very excited to be on my way to the National Genetics Course in Madrid @segenetica.bsky.social
It is always very special to go back to Spain for scientific reasons. It would be hard to convince uni student Joaquina of what would come.
Impressive (aka intimidating 😂) line up
It is always very special to go back to Spain for scientific reasons. It would be hard to convince uni student Joaquina of what would come.
Impressive (aka intimidating 😂) line up
Best part of the job: visiting other places and discussing fun science. This time thanks to @sonnenlab.bsky.social
September 4, 2025 at 9:08 PM
Best part of the job: visiting other places and discussing fun science. This time thanks to @sonnenlab.bsky.social
Reposted by Joaquina Delas
Do you have friends with questions about fertility? Egg freezing? Embryo research? IVF? Stem Cells? If you're UK-based this Friday, the BBC are hosting a Question of Science and tickets are still available. PLUS you can submit a question in advance to ask the panelists 🎤
shorturl.at/BCTW7
shorturl.at/BCTW7
A Question of Science | What's the future of fertility?
A new podcast produced for the Crick by BBC Studios Science Unit.
www.crick.ac.uk
September 2, 2025 at 3:11 PM
Do you have friends with questions about fertility? Egg freezing? Embryo research? IVF? Stem Cells? If you're UK-based this Friday, the BBC are hosting a Question of Science and tickets are still available. PLUS you can submit a question in advance to ask the panelists 🎤
shorturl.at/BCTW7
shorturl.at/BCTW7
What an excellent fall program! Don't miss these talks!
We're super excited to announce the entire lineup for the Fall season of Fragile Nucleosome Seminars, starting on Sept 10th at 1200 EDT / 1600 UTC with @gracebower.bsky.social and @creminslab.bsky.social!
register here for the entire series: us06web.zoom.us/webinar/regi...
register here for the entire series: us06web.zoom.us/webinar/regi...
September 1, 2025 at 4:00 PM
What an excellent fall program! Don't miss these talks!
Check out the latest work by @dbenzinger.bsky.social and @jamesbriscoe.bsky.social !
Building gradients in space and time.
I am extremely biased but the Dec 15 issue of Dev Cell is 🔥🔥
Building gradients in space and time.
I am extremely biased but the Dec 15 issue of Dev Cell is 🔥🔥
Our latest: We developed a chemo-optogenetic system for precise spatiotemporal control of morphogen production. Using dual light + small molecule control of Sonic Hedgehog production, we recapitulated neural tube patterning in vitro & measured spread of Shh
🧵
www.sciencedirect.com/science/arti...
🧵
www.sciencedirect.com/science/arti...
Investigating morphogen and patterning dynamics with optogenetic control of morphogen production
Morphogen gradients provide the patterning cues that instruct cell fate decisions during development. Here, we establish an optogenetic system for the…
www.sciencedirect.com
August 26, 2025 at 12:40 PM
Check out the latest work by @dbenzinger.bsky.social and @jamesbriscoe.bsky.social !
Building gradients in space and time.
I am extremely biased but the Dec 15 issue of Dev Cell is 🔥🔥
Building gradients in space and time.
I am extremely biased but the Dec 15 issue of Dev Cell is 🔥🔥
Read more about @sermenchero.bsky.social 's work in this PNAS Journal Club. #opossums!
In #opossums and other #marsupials, #GeneExpression follows familiar rules, but at an unusual pace. In PNAS Journal Club: www.pnas.org/post/journal...
#DevelopmentalBiology #evolution #embryo #transcriptome
#DevelopmentalBiology #evolution #embryo #transcriptome
August 21, 2025 at 7:30 PM
Read more about @sermenchero.bsky.social 's work in this PNAS Journal Club. #opossums!
New from our colleagues across the hall, @yanlanmao.bsky.social and @giuliapaci.bsky.social
How can 3D topology tune patterning? Read below!
How can 3D topology tune patterning? Read below!
Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️
August 11, 2025 at 7:58 PM
New from our colleagues across the hall, @yanlanmao.bsky.social and @giuliapaci.bsky.social
How can 3D topology tune patterning? Read below!
How can 3D topology tune patterning? Read below!