Albert Pol Lab
@albertpol.bsky.social
Cell biology, lipids, and lipid droplets. ICREA Research Professor at Fundació Clínic Barcelona/IDIBAPS/University of Barcelona.
Pinned
Albert Pol Lab
@albertpol.bsky.social
· Nov 13
Our group investigates the role of #lipid droplets (green) in killing intracellular pathogens (blue, E coli in human macrophages) when they are searching for nutrients. In our family we have nicknamed them defensive lipid droplets and FATal attraction. Credit @robparton.bsky.social @UQpress
Reposted by Albert Pol Lab
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
@IBECBarcelona
www.biorxiv.org/content/10.1...
September 1, 2025 at 3:31 PM
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
@IBECBarcelona
www.biorxiv.org/content/10.1...
Reposted by Albert Pol Lab
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Albert Pol Lab
Tenure track position alert! Assistant Professor of Molecular Therapeutics in MCB @UCBerkeley. Apply and come be our colleague! 🎉
aprecruit.berkeley.edu/JPF05098
aprecruit.berkeley.edu/JPF05098
August 21, 2025 at 4:00 AM
Tenure track position alert! Assistant Professor of Molecular Therapeutics in MCB @UCBerkeley. Apply and come be our colleague! 🎉
aprecruit.berkeley.edu/JPF05098
aprecruit.berkeley.edu/JPF05098
Reposted by Albert Pol Lab
💥 A gut microbe metabolite that drives #atherosclerosis?
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41... #OpenAccess at
@Nature
@CNIC_CARDIO
#CVD #immunosky #cardiosky #microbiomesky
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41... #OpenAccess at
@Nature
@CNIC_CARDIO
#CVD #immunosky #cardiosky #microbiomesky
Imidazole propionate is a driver and therapeutic target in atherosclerosis - Nature
Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the imidazoline-1 ...
nature.com
July 16, 2025 at 5:37 PM
💥 A gut microbe metabolite that drives #atherosclerosis?
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41... #OpenAccess at
@Nature
@CNIC_CARDIO
#CVD #immunosky #cardiosky #microbiomesky
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41... #OpenAccess at
@Nature
@CNIC_CARDIO
#CVD #immunosky #cardiosky #microbiomesky
Reposted by Albert Pol Lab
Journal of Cell Science is published by a not-for-profit charitable organisation (@biologists.bsky.social)
that exists to benefit science, not shareholders. We provide Travelling Fellowships, Training Grants, support for ECRs and more.
For details, visit: journals.biologists.com/jcs/pages/re...
that exists to benefit science, not shareholders. We provide Travelling Fellowships, Training Grants, support for ECRs and more.
For details, visit: journals.biologists.com/jcs/pages/re...
July 9, 2025 at 3:25 PM
Journal of Cell Science is published by a not-for-profit charitable organisation (@biologists.bsky.social)
that exists to benefit science, not shareholders. We provide Travelling Fellowships, Training Grants, support for ECRs and more.
For details, visit: journals.biologists.com/jcs/pages/re...
that exists to benefit science, not shareholders. We provide Travelling Fellowships, Training Grants, support for ECRs and more.
For details, visit: journals.biologists.com/jcs/pages/re...
Reposted by Albert Pol Lab
Congratulations to newly elected @embo.org members
Special shout out to friends & colleagues: Andy Oates, Jody Rosemblatt & Pete Currie
Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO share.google/9z7IS2lZBmll...
Special shout out to friends & colleagues: Andy Oates, Jody Rosemblatt & Pete Currie
Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO share.google/9z7IS2lZBmll...
Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO
Sixty-nine new members join the community of leading life scientists in Europe and beyond
share.google
July 1, 2025 at 5:39 PM
Congratulations to newly elected @embo.org members
Special shout out to friends & colleagues: Andy Oates, Jody Rosemblatt & Pete Currie
Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO share.google/9z7IS2lZBmll...
Special shout out to friends & colleagues: Andy Oates, Jody Rosemblatt & Pete Currie
Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO share.google/9z7IS2lZBmll...
Reposted by Albert Pol Lab
Well what do you know!? This might be the most interesting unorthodox orthodox metabolism paper this year.
Triglycerides are an important fuel reserve for synapse function in the brain - Nature Metabolism
Kumar et al. show that under glucose-depleted conditions, neurons can use fatty acids as an alternative source of energy to support synaptic function.
www.nature.com
July 2, 2025 at 4:16 AM
Well what do you know!? This might be the most interesting unorthodox orthodox metabolism paper this year.
Reposted by Albert Pol Lab
The #MembraneTrafficking online seminars are back this Thursday (June 26th, 5pm CEST). We'll hear from @jnuechel.bsky.social about how to find the right partner for a TANGO, and from Maohan Su about the organizational principles of the Golgi. @ishier.bsky.social @franbottanelli.bsky.social
MEMBRANE TRAFFICKING | Membrane Trafficking
felixcampelo.wixsite.com
June 23, 2025 at 7:46 AM
The #MembraneTrafficking online seminars are back this Thursday (June 26th, 5pm CEST). We'll hear from @jnuechel.bsky.social about how to find the right partner for a TANGO, and from Maohan Su about the organizational principles of the Golgi. @ishier.bsky.social @franbottanelli.bsky.social
Reposted by Albert Pol Lab
Happy summer!! A new issue of #cebooc is here! Read the latest paper on oocyte cell biology here:
biomed.news/bims-cebooc/...
Thanks @biomednews.bsky.social for preselecting!
biomed.news/bims-cebooc/...
Thanks @biomednews.bsky.social for preselecting!
June 22, 2025 at 8:39 AM
Happy summer!! A new issue of #cebooc is here! Read the latest paper on oocyte cell biology here:
biomed.news/bims-cebooc/...
Thanks @biomednews.bsky.social for preselecting!
biomed.news/bims-cebooc/...
Thanks @biomednews.bsky.social for preselecting!
Reposted by Albert Pol Lab
Thrilled this paper is out! We solved the first cocrystal structure of FSP1 with an inhibitor (FSEN1), providing mechanistic insight & a foundation for medchem. Led by Amalia Megarioti & Sitao Zhang. A terrific collaboration with Da Jia.
Brief Skytorial!
1/9
Brief Skytorial!
1/9
Cocrystal structure reveals the mechanism of FSP1 inhibition by FSEN1 | PNAS
FSP1 is an FAD-dependent oxidoreductase that uses NAD(P)H to regenerate the reduced
forms of lipophilic quinone antioxidants, such as coenzyme Q10 ...
www.pnas.org
May 29, 2025 at 6:02 PM
Thrilled this paper is out! We solved the first cocrystal structure of FSP1 with an inhibitor (FSEN1), providing mechanistic insight & a foundation for medchem. Led by Amalia Megarioti & Sitao Zhang. A terrific collaboration with Da Jia.
Brief Skytorial!
1/9
Brief Skytorial!
1/9
Reposted by Albert Pol Lab
What an inspiring morning at the CatCat Symposium! Thank you so much for inviting me @gallegolab.bsky.social and @felixmendu.bsky.social, it's been a pleasure visiting you in Barcelona 😊
May 27, 2025 at 6:03 PM
What an inspiring morning at the CatCat Symposium! Thank you so much for inviting me @gallegolab.bsky.social and @felixmendu.bsky.social, it's been a pleasure visiting you in Barcelona 😊
Reposted by Albert Pol Lab
Pleased to see Kevin's paper on the Retromer complex interaction with yeast Vps5 and Vps17 proteins now online!
Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer - Nature Communications
Retromer complex cooperates with Vps5 and Vps17 in yeast to traffic transmembrane proteins. Here, the authors present structural and functional studies that reveal the mechanism of Retromer and Vps5 i...
www.nature.com
April 16, 2025 at 1:59 AM
Pleased to see Kevin's paper on the Retromer complex interaction with yeast Vps5 and Vps17 proteins now online!
Reposted by Albert Pol Lab
We are looking for a PhD candidate starting on the 01-10-2025. The project aims to understand how the host cells use copper and oxidative species to fight Salmonella infection and how this pathogen evades this antimicrobial response.
SHORT DEADLINE ! 20-04-2025
jobs.inrae.fr/en/ot-25517
SHORT DEADLINE ! 20-04-2025
jobs.inrae.fr/en/ot-25517
March 27, 2025 at 9:20 AM
We are looking for a PhD candidate starting on the 01-10-2025. The project aims to understand how the host cells use copper and oxidative species to fight Salmonella infection and how this pathogen evades this antimicrobial response.
SHORT DEADLINE ! 20-04-2025
jobs.inrae.fr/en/ot-25517
SHORT DEADLINE ! 20-04-2025
jobs.inrae.fr/en/ot-25517
Reposted by Albert Pol Lab
Our paper on the regulation of the tight junction leak pathway by Arhgap12/N-Wasp is out ! www.cell.com/cell-reports...
ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability
Tambrin et al. show that the Cdc42/Rac GAP ARHGAP12 promotes the flux of macromolecules
across tight junctions by suppressing junctional actin assembly and tension via N-WASP
and the Arp2/3 complex. T...
www.cell.com
April 8, 2025 at 6:22 AM
Our paper on the regulation of the tight junction leak pathway by Arhgap12/N-Wasp is out ! www.cell.com/cell-reports...
Reposted by Albert Pol Lab
Did you know…
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
April 9, 2025 at 2:32 PM
Did you know…
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
Reposted by Albert Pol Lab
Together with @gallegolab.bsky.social we are organizing the next CATCAT morning on "Dynamics in biology, from molecules to tissues", with an amazing lineup of local and international speakers. If in Barcelona on May 26th, don't miss it, it's free! www.catcat-celltissuebiology.cat/event/9th-ca...
March 14, 2025 at 9:57 AM
Together with @gallegolab.bsky.social we are organizing the next CATCAT morning on "Dynamics in biology, from molecules to tissues", with an amazing lineup of local and international speakers. If in Barcelona on May 26th, don't miss it, it's free! www.catcat-celltissuebiology.cat/event/9th-ca...
Reposted by Albert Pol Lab
A Postdoctoral Research position is available in the group of Lipid Trafficking and Disease (@idibaps.bsky.social Barcelona) to participate in the ERC granted project ‘Lipid droplets as innate immunity hubs’. @albertpol.bsky.social @albertherms.bsky.social focalplane.biologists.com/cell-biology...
Postdoctoral Researcher (G1) at the Lipid trafficking and disease - FocalPlane
A Postdoctoral Research position is available in the group of “Lipid Trafficking and Disease (IDIBAPS, Barcelona)” to participate in the ERC granted project “Lipid droplets as innate immunity hubs (DR...
focalplane.biologists.com
February 7, 2025 at 1:21 PM
A Postdoctoral Research position is available in the group of Lipid Trafficking and Disease (@idibaps.bsky.social Barcelona) to participate in the ERC granted project ‘Lipid droplets as innate immunity hubs’. @albertpol.bsky.social @albertherms.bsky.social focalplane.biologists.com/cell-biology...
Reposted by Albert Pol Lab
Looking for a PostDoc? Exciting science and great city! Join us @albertpol.bsky.social @albertherms.bsky.social in @idibaps.bsky.social Barcelona to work in an @ercresearch.bsky.social funded project to study how lipid droplets attract and kill bacteria. www.clinicbarcelona.org/uploads/medi...
February 2, 2025 at 11:08 AM
Looking for a PostDoc? Exciting science and great city! Join us @albertpol.bsky.social @albertherms.bsky.social in @idibaps.bsky.social Barcelona to work in an @ercresearch.bsky.social funded project to study how lipid droplets attract and kill bacteria. www.clinicbarcelona.org/uploads/medi...
Reposted by Albert Pol Lab
What are 26 different Rab GTPases doing on Lipid Droplets? Are lipids transferred by membrane contact sites? Moving the FAT: Emerging roles of Rab GTPases in the regulation of lipid droplet contact sites M Alonso @albertpol.bsky.social and Harriet P Lo www.sciencedirect.com/science/arti...
February 2, 2025 at 11:51 AM
What are 26 different Rab GTPases doing on Lipid Droplets? Are lipids transferred by membrane contact sites? Moving the FAT: Emerging roles of Rab GTPases in the regulation of lipid droplet contact sites M Alonso @albertpol.bsky.social and Harriet P Lo www.sciencedirect.com/science/arti...
What are 26 different Rab GTPases doing on Lipid Droplets? Are lipids transferred by membrane contact sites? Moving the FAT: Emerging roles of Rab GTPases in the regulation of lipid droplet contact sites M Alonso @albertpol.bsky.social and Harriet P Lo www.sciencedirect.com/science/arti...
February 2, 2025 at 11:51 AM
What are 26 different Rab GTPases doing on Lipid Droplets? Are lipids transferred by membrane contact sites? Moving the FAT: Emerging roles of Rab GTPases in the regulation of lipid droplet contact sites M Alonso @albertpol.bsky.social and Harriet P Lo www.sciencedirect.com/science/arti...
Looking for a PostDoc? Exciting science and great city! Join us @albertpol.bsky.social @albertherms.bsky.social in @idibaps.bsky.social Barcelona to work in an @ercresearch.bsky.social funded project to study how lipid droplets attract and kill bacteria. www.clinicbarcelona.org/uploads/medi...
February 2, 2025 at 11:08 AM
Looking for a PostDoc? Exciting science and great city! Join us @albertpol.bsky.social @albertherms.bsky.social in @idibaps.bsky.social Barcelona to work in an @ercresearch.bsky.social funded project to study how lipid droplets attract and kill bacteria. www.clinicbarcelona.org/uploads/medi...
Reposted by Albert Pol Lab
JCS Editor-in-Chief @drmichaelway.bsky.social introduces our new Associate Editors.
We are delighted to welcome Sophie Acton @actonlab.bsky.social, Pedro Carvalho, @guijacquemet.bsky.social, @ckirchhelle.bsky.social and Aryeh Warmflash to the JCS team.
journals.biologists.com/jcs/article/...
We are delighted to welcome Sophie Acton @actonlab.bsky.social, Pedro Carvalho, @guijacquemet.bsky.social, @ckirchhelle.bsky.social and Aryeh Warmflash to the JCS team.
journals.biologists.com/jcs/article/...
January 27, 2025 at 1:01 PM
JCS Editor-in-Chief @drmichaelway.bsky.social introduces our new Associate Editors.
We are delighted to welcome Sophie Acton @actonlab.bsky.social, Pedro Carvalho, @guijacquemet.bsky.social, @ckirchhelle.bsky.social and Aryeh Warmflash to the JCS team.
journals.biologists.com/jcs/article/...
We are delighted to welcome Sophie Acton @actonlab.bsky.social, Pedro Carvalho, @guijacquemet.bsky.social, @ckirchhelle.bsky.social and Aryeh Warmflash to the JCS team.
journals.biologists.com/jcs/article/...
Reposted by Albert Pol Lab
This is just a reminder that the #cancermetabolism and #mitochondrialbiology community is ever-growing, and the third starter pack is becoming very juicy.
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
Starter pack 3: go.bsky.app/7Uwa6fb
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
Starter pack 3: go.bsky.app/7Uwa6fb
January 26, 2025 at 7:47 AM
This is just a reminder that the #cancermetabolism and #mitochondrialbiology community is ever-growing, and the third starter pack is becoming very juicy.
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
Starter pack 3: go.bsky.app/7Uwa6fb
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
Starter pack 3: go.bsky.app/7Uwa6fb
Reposted by Albert Pol Lab
We are looking for a postdoc for an ERC funded project at @albertpol.bsky.social Lab at @idibaps.bsky.social in Barcelona. Do you want to use 3D #epithelioids to study the role of lipid droplets against bacterial infections? Come and join us!👇
www.clinicbarcelona.org/uploads/medi...
www.clinicbarcelona.org/uploads/medi...
January 20, 2025 at 12:37 PM
We are looking for a postdoc for an ERC funded project at @albertpol.bsky.social Lab at @idibaps.bsky.social in Barcelona. Do you want to use 3D #epithelioids to study the role of lipid droplets against bacterial infections? Come and join us!👇
www.clinicbarcelona.org/uploads/medi...
www.clinicbarcelona.org/uploads/medi...