A study from the University of Rochester’s Wilmot Cancer Institute links taurine, a common energy drink ingredient, to increased leukemia growth by fueling cancer cells through glycolysis. Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to accelerate cancer pro...
January 19, 2026 at 12:29 PM
A study from the University of Rochester’s Wilmot Cancer Institute links taurine, a common energy drink ingredient, to increased leukemia growth by fueling cancer cells through glycolysis. Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to accelerate cancer pro...
A study from the University of Rochester’s Wilmot Cancer Institute links taurine, a common energy drink ingredient, to increased leukemia growth by fueling cancer cells through glycolysis. Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to accelerate cancer pro...
January 19, 2026 at 12:29 PM
A study from the University of Rochester’s Wilmot Cancer Institute links taurine, a common energy drink ingredient, to increased leukemia growth by fueling cancer cells through glycolysis. Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to accelerate cancer pro...
A study from the University of Rochester’s Wilmot Cancer Institute links taurine, a common energy drink ingredient, to increased leukemia growth by fueling cancer cells through glycolysis.
Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to 🔗↗️… […]
Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to 🔗↗️… […]
Original post on zpravobot.news
zpravobot.news
January 19, 2026 at 12:25 PM
A study from the University of Rochester’s Wilmot Cancer Institute links taurine, a common energy drink ingredient, to increased leukemia growth by fueling cancer cells through glycolysis.
Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to 🔗↗️… […]
Taurine, naturally produced in the body and added to drinks like Red Bull, is shown to 🔗↗️… […]
...Glucose capture (OMM-detached HK), commitment to glycolysis (PFK1), and proton-coupled lactate efflux (MCT) - largely in line with elegant work from the Rabinowitz lab derived from using a completely orthogonal system/approach. 7/n
January 16, 2026 at 4:29 PM
...Glucose capture (OMM-detached HK), commitment to glycolysis (PFK1), and proton-coupled lactate efflux (MCT) - largely in line with elegant work from the Rabinowitz lab derived from using a completely orthogonal system/approach. 7/n
Contrary to traditional theories, we found that HK detachment from the mitochondria actually supports both cell growth and aerobic glycolysis ("the Warburg effect") 3/n
January 16, 2026 at 4:28 PM
Contrary to traditional theories, we found that HK detachment from the mitochondria actually supports both cell growth and aerobic glycolysis ("the Warburg effect") 3/n
#Article in #MedComm
This article identified first time a critical #m6A modification of #circIST1 on miR-140-3p/miR-182-HIF1α regulatory network involved in the #HCC progression and #tumor #glycolysis. doi.org/10.1002/mco2...
This article identified first time a critical #m6A modification of #circIST1 on miR-140-3p/miR-182-HIF1α regulatory network involved in the #HCC progression and #tumor #glycolysis. doi.org/10.1002/mco2...
N6‐Methyladenosine Modification of circIST1 Promotes Hypoxia‐Inducible Factor α–mediated Glycolysis and Progression in Hepatocellular Carcinoma
We identified first time a critical m6A modification of circIST1 on miR-140-3p/miR-182-HIF1α regulatory network involved in the HCC progression and tumor glycolysis, gaining mechanistic insights into...
doi.org
January 16, 2026 at 3:10 AM
#Article in #MedComm
This article identified first time a critical #m6A modification of #circIST1 on miR-140-3p/miR-182-HIF1α regulatory network involved in the #HCC progression and #tumor #glycolysis. doi.org/10.1002/mco2...
This article identified first time a critical #m6A modification of #circIST1 on miR-140-3p/miR-182-HIF1α regulatory network involved in the #HCC progression and #tumor #glycolysis. doi.org/10.1002/mco2...
The dev brain relies heavily on glycolysis. If fetal glucose and insulin levels are elevated via maternal hyperglycemia, HA synthesis capacity may rise, while oxidative or inflammatory stress accelerates HA turnover. Together, this could influence developmental timing and critical-period regulation.
January 15, 2026 at 9:05 PM
The dev brain relies heavily on glycolysis. If fetal glucose and insulin levels are elevated via maternal hyperglycemia, HA synthesis capacity may rise, while oxidative or inflammatory stress accelerates HA turnover. Together, this could influence developmental timing and critical-period regulation.
ENO1 stimulates lactate & ATP production by regulating #Glycolysis, affecting #LactateHomeostasis & intracellular ATP pools, which modulate the AMPK/#mTOR & PI3K/AKT signaling, driving #GastricCancer stemness & progression.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
January 15, 2026 at 2:30 PM
ENO1 stimulates lactate & ATP production by regulating #Glycolysis, affecting #LactateHomeostasis & intracellular ATP pools, which modulate the AMPK/#mTOR & PI3K/AKT signaling, driving #GastricCancer stemness & progression.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
The Ets transcription factor ETV4 regulates FGF1-dependent proliferation and glycolysis in ER-positive breast cancer https://www.biorxiv.org/content/10.64898/2026.01.13.699240v1
January 14, 2026 at 7:47 PM
The Ets transcription factor ETV4 regulates FGF1-dependent proliferation and glycolysis in ER-positive breast cancer https://www.biorxiv.org/content/10.64898/2026.01.13.699240v1
The Ets transcription factor ETV4 regulates FGF1-dependent proliferation and glycolysis in ER-positive breast cancer https://www.biorxiv.org/content/10.64898/2026.01.13.699240v1
January 14, 2026 at 7:47 PM
The Ets transcription factor ETV4 regulates FGF1-dependent proliferation and glycolysis in ER-positive breast cancer https://www.biorxiv.org/content/10.64898/2026.01.13.699240v1
MAT2A enhances PARN transcription via SRF to accelerate glycolysis and drive malignant progression in osteosarcoma
https://www.europesays.com/ie/283115/
Prater, S. & McKeon, B. in StatPearls (StatPearls Publishing Copyright © 2024, StatPearls Publishing LLC., 2024). Du, X.…
https://www.europesays.com/ie/283115/
Prater, S. & McKeon, B. in StatPearls (StatPearls Publishing Copyright © 2024, StatPearls Publishing LLC., 2024). Du, X.…
MAT2A enhances PARN transcription via SRF to accelerate glycolysis and drive malignant progression in osteosarcoma - Ireland
Prater, S. & McKeon, B. in StatPearls (StatPearls Publishing Copyright © 2024, StatPearls Publishing LLC., 2024).
www.europesays.com
January 14, 2026 at 3:00 AM
MAT2A enhances PARN transcription via SRF to accelerate glycolysis and drive malignant progression in osteosarcoma
https://www.europesays.com/ie/283115/
Prater, S. & McKeon, B. in StatPearls (StatPearls Publishing Copyright © 2024, StatPearls Publishing LLC., 2024). Du, X.…
https://www.europesays.com/ie/283115/
Prater, S. & McKeon, B. in StatPearls (StatPearls Publishing Copyright © 2024, StatPearls Publishing LLC., 2024). Du, X.…
From the US:
Post-COVID impairment of memory T cell responses to community-acquired pathogens can be rectified by activating cellular metabolism
www.biorxiv.org/content/10.6...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
Post-COVID impairment of memory T cell responses to community-acquired pathogens can be rectified by activating cellular metabolism
www.biorxiv.org/content/10.6...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
January 14, 2026 at 2:08 AM
From the US:
Post-COVID impairment of memory T cell responses to community-acquired pathogens can be rectified by activating cellular metabolism
www.biorxiv.org/content/10.6...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
Post-COVID impairment of memory T cell responses to community-acquired pathogens can be rectified by activating cellular metabolism
www.biorxiv.org/content/10.6...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
He was dealing with things like the citric acid cycle, glycolysis, aerobic vs. anerobic, and other cellular respiration topics.
One of the questions asked for something like four specific pathways something can happen.
One of the questions asked for something like four specific pathways something can happen.
January 13, 2026 at 5:46 PM
He was dealing with things like the citric acid cycle, glycolysis, aerobic vs. anerobic, and other cellular respiration topics.
One of the questions asked for something like four specific pathways something can happen.
One of the questions asked for something like four specific pathways something can happen.
#ThisWeekInNPP
In this comment, the authors argue that impaired brain energetics, characterized by a shift from oxidative phosphorylation to glycolysis, is a shared feature of neuropsychiatric disorders and a promising therapeutic target
www.nature.com/artic...
4/8
In this comment, the authors argue that impaired brain energetics, characterized by a shift from oxidative phosphorylation to glycolysis, is a shared feature of neuropsychiatric disorders and a promising therapeutic target
www.nature.com/artic...
4/8
Imaging brain energetics to advance metabolic psychiatry
Neuropsychopharmacology - Imaging brain energetics to advance metabolic psychiatry
www.nature.com
January 13, 2026 at 4:08 PM
#ThisWeekInNPP
In this comment, the authors argue that impaired brain energetics, characterized by a shift from oxidative phosphorylation to glycolysis, is a shared feature of neuropsychiatric disorders and a promising therapeutic target
www.nature.com/artic...
4/8
In this comment, the authors argue that impaired brain energetics, characterized by a shift from oxidative phosphorylation to glycolysis, is a shared feature of neuropsychiatric disorders and a promising therapeutic target
www.nature.com/artic...
4/8
🦠 Gut–lung crosstalk in sepsis: Dysbiosis + barrier failure → LPS translocation, lung inflammation, NETs, ALI/ARDS. Immune shift to glycolysis (HIF-1α), ROS/mtDNA, gut metabolites worsen injury. Restoring the axis (probiotics/FMT, vagal activation, immunometabolic profiling) may improve outcomes.
GastroAGI - AI Chat for Gastroenterology Students
Ask AI-powered questions about gastroenterology and enhance your academic learning.
gastroagi.com
January 13, 2026 at 12:55 PM
🦠 Gut–lung crosstalk in sepsis: Dysbiosis + barrier failure → LPS translocation, lung inflammation, NETs, ALI/ARDS. Immune shift to glycolysis (HIF-1α), ROS/mtDNA, gut metabolites worsen injury. Restoring the axis (probiotics/FMT, vagal activation, immunometabolic profiling) may improve outcomes.
Normal blood stem cells resist heme biosynthesis inhibition far better than leukemic cells. Combining heme pathway blockers with glycolysis inhibitors shows potent synergy against AML. @petermaccc.bsky.social @cp-cell.bsky.social
doi.org/10.1016/j.ce... 🧪
3/3
doi.org/10.1016/j.ce... 🧪
3/3
January 13, 2026 at 12:52 PM
Normal blood stem cells resist heme biosynthesis inhibition far better than leukemic cells. Combining heme pathway blockers with glycolysis inhibitors shows potent synergy against AML. @petermaccc.bsky.social @cp-cell.bsky.social
doi.org/10.1016/j.ce... 🧪
3/3
doi.org/10.1016/j.ce... 🧪
3/3
22. 🔋 Synergistic Strategies: Ketones + Near-Infrared Light
Ketones
• Supply an alternative fuel when glycolysis is impaired.
• Cross the blood-brain barrier and convert to acetyl-CoA, feeding directly into the TCA cycle.
• Improve mitochondrial efficiency and reduce ROS.
Ketones
• Supply an alternative fuel when glycolysis is impaired.
• Cross the blood-brain barrier and convert to acetyl-CoA, feeding directly into the TCA cycle.
• Improve mitochondrial efficiency and reduce ROS.
January 12, 2026 at 1:00 AM
22. 🔋 Synergistic Strategies: Ketones + Near-Infrared Light
Ketones
• Supply an alternative fuel when glycolysis is impaired.
• Cross the blood-brain barrier and convert to acetyl-CoA, feeding directly into the TCA cycle.
• Improve mitochondrial efficiency and reduce ROS.
Ketones
• Supply an alternative fuel when glycolysis is impaired.
• Cross the blood-brain barrier and convert to acetyl-CoA, feeding directly into the TCA cycle.
• Improve mitochondrial efficiency and reduce ROS.
Teaching glycolysis this week in my biochemistry class, and cannot recommend this article enough. I really wish I had been taught this critical pathway from a perspective of (bio)chemical logic, rather than memorizing ten enzymatic reactions...
www.nature.com/articles/nch...
www.nature.com/articles/nch...
Client Challenge
www.nature.com
January 11, 2026 at 7:05 PM
Teaching glycolysis this week in my biochemistry class, and cannot recommend this article enough. I really wish I had been taught this critical pathway from a perspective of (bio)chemical logic, rather than memorizing ten enzymatic reactions...
www.nature.com/articles/nch...
www.nature.com/articles/nch...
#WeekendRead! #SmartTumor! Liu, Kroemer, Tang, Wang &co show @cp-cell.bsky.social that ferroptotic tumor cells release GPX4 dampening anti-tumor responses by signaling in DCs via ZP3 receptors, thus blocking glycolysis & impairing cytotoxic T cell activation!
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Extracellular GPX4 impairs antitumor immunity via dendritic ZP3 receptors
GPX4 released by ferroptotic cancer cells suppresses dendritic cell maturation and
T cell priming by binding to ZP3. Blocking the GPX4-ZP3 interaction restores dendritic
activity, boosts cytotoxic T c...
www.cell.com
January 10, 2026 at 4:34 PM
#WeekendRead! #SmartTumor! Liu, Kroemer, Tang, Wang &co show @cp-cell.bsky.social that ferroptotic tumor cells release GPX4 dampening anti-tumor responses by signaling in DCs via ZP3 receptors, thus blocking glycolysis & impairing cytotoxic T cell activation!
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Decoding TREM2 Signaling Pathways
Linking Macrophage Glycolysis to Inflammatory Diseases in the CNS🔓
www.neurology.org/doi/full/10....
Linking Macrophage Glycolysis to Inflammatory Diseases in the CNS🔓
www.neurology.org/doi/full/10....
Decoding TREM2 Signaling Pathways | Neurology Neuroimmunology & Neuroinflammation
Triggering receptor expressed on myeloid cells 2 (TREM2) is a key immunomodulatory
receptor broadly expressed on myeloid cells such as macrophages and microglia. It
plays versatile roles in neurodegen...
www.neurology.org
January 9, 2026 at 10:27 PM
Decoding TREM2 Signaling Pathways
Linking Macrophage Glycolysis to Inflammatory Diseases in the CNS🔓
www.neurology.org/doi/full/10....
Linking Macrophage Glycolysis to Inflammatory Diseases in the CNS🔓
www.neurology.org/doi/full/10....
For example for #PEM/exertional intolerance: Variants in ACADM/HADHA/ELOVL4/ENO3 (FAO/glycolysis) and SLC7A9 (AA transport) suggest reduced ATP & metabolic flexibility. KCNJ18/CACNA1S/SLC12A3 alter K⁺/Ca²⁺/Cl⁻ handling; SPTA1/SLC4A1 impact RBC oxygen delivery. Not one #MECFS path... many.
January 9, 2026 at 6:16 PM
For example for #PEM/exertional intolerance: Variants in ACADM/HADHA/ELOVL4/ENO3 (FAO/glycolysis) and SLC7A9 (AA transport) suggest reduced ATP & metabolic flexibility. KCNJ18/CACNA1S/SLC12A3 alter K⁺/Ca²⁺/Cl⁻ handling; SPTA1/SLC4A1 impact RBC oxygen delivery. Not one #MECFS path... many.
Examples: ENO3 (glycolysis), ACADM/HADHA (FAO), KCNJ18/SLC12A3 (channel/transport), SPTA1/SLC4A1 (RBC), MYH7 (sarcomere). It is a very small study; so there are limitations, but several findings are hypothesis generating or potentially actionable or testable in clinic-style workflows.. #MECFS
January 9, 2026 at 6:12 PM
Examples: ENO3 (glycolysis), ACADM/HADHA (FAO), KCNJ18/SLC12A3 (channel/transport), SPTA1/SLC4A1 (RBC), MYH7 (sarcomere). It is a very small study; so there are limitations, but several findings are hypothesis generating or potentially actionable or testable in clinic-style workflows.. #MECFS
"Digital FDG-PET Detects MYD88 Mutation-Driven Glycolysis in Primary CNS Lymphoma"
doi.org/10.3174/ajnr...
doi.org/10.3174/ajnr...
January 9, 2026 at 4:02 PM
"Digital FDG-PET Detects MYD88 Mutation-Driven Glycolysis in Primary CNS Lymphoma"
doi.org/10.3174/ajnr...
doi.org/10.3174/ajnr...