Yushan Wang
yosh3118.bsky.social
Yushan Wang
@yosh3118.bsky.social
PhD in Neuroscience, traumatic brain injury research scientist. Proud Canadian 🇨🇦. Never had Covid, still trying hard to avoid it. Interested in all things medicine.
Reposted by Yushan Wang
In a review of 37 studies, encompassing 2,965,467 patients, 15% of Covid survivors suffered from cardiovascular sequelae. This underscores the risk of cardiovascular disease in #LongCovid

bmcmedicine.biomedcentral.com/articles/10....
Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis - BMC Medicine
Background Since its emergence in 2019, COVID-19 has continued to pose significant threats to both the physical and mental health of the global population, as well as to healthcare systems worldwide (...
bmcmedicine.biomedcentral.com
February 8, 2025 at 12:43 AM
Reposted by Yushan Wang
Covid and the thyroid ⚠️

A review of 53 studies sheds light on thyroid dysfunction in COVID-19-related disorders and #LongCovid, "underscoring the complex nature of SARS-CoV-2 infection and its far-reaching impacts on human health."
February 6, 2025 at 9:55 AM
Reposted by Yushan Wang
Both mild and severe cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are linked to changes in brain biomarkers associated with Alzheimer’s disease.

But let’s keep getting it over and over right ?

www.news-medical.net/news/2025020...
Does COVID increase the risk of Alzheimer’s disease?
COVID-19, even in mild cases, is linked to changes in Alzheimer’s disease-related brain biomarkers comparable to four years of aging. This study raises concerns about long-term neurological risks and ...
www.news-medical.net
February 3, 2025 at 11:53 AM
Reposted by Yushan Wang
A benefit of prior vaccination when there's a breakthrough infection: putting the brakes on a maladaptive innate immune response
www.science.org/doi/10.1126/...
Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infection
SARS-CoV-2 breakthrough infections in previously vaccinated individuals are characterized by reduced activation of innate immune responses.
www.science.org
January 29, 2025 at 7:18 PM
Reposted by Yushan Wang
Long COVID Impairs Exercise Capacity and Cognition for Years.

"A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two years after infection."
Long COVID Impairs Exercise Capacity and Cognition for Years - Neuroscience News
A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two yea...
neurosciencenews.com
January 24, 2025 at 1:08 AM
Reposted by Yushan Wang
The study suggests that acute COVID-19, irrespective of Long COVID status, is associated with an increased risk of car crashes, likely due to neurological changes caused by SARS-CoV-2.

www.neurology.org/doi/10.1212/...

#LongCovid
Driving Under the Cognitive Influence of COVID-19: Exploring the Impact of Acute SARS-CoV-2 Infection on Road Safety | Neurology
ObjectiveThis study evaluated the association between acute COVID-19 cases and the number of car crashes with varying COVID-19 vaccination rates, Long COVID rates, and COVID-19 mitigation strategies.B...
www.neurology.org
January 19, 2025 at 8:06 PM
Reposted by Yushan Wang
Sweden: "Not implementing a mandatory lockdown was blamed for the higher mortality seen in Sweden. In a modeling study... researchers found that the infection rates could have been reduced by 75% and mortality could have been reduced by 25%"

kevinmd.com/2025/01/swed...
Sweden’s controversial COVID-19 strategy: lessons from higher mortality rates
Sweden's relaxed approach to COVID-19, emphasizing voluntary compliance and avoiding strict lockdowns, resulted in higher mortality rates compared to neighboring countries, despite preserving individu...
kevinmd.com
January 21, 2025 at 1:06 AM
Reposted by Yushan Wang
More evidence is coming up pointing to viral infections being connected with Alzheimer's and Parkinson's diseases. 2025 will be the neurovirology year!
We are finishing a study funded by the Michael J Fox Foundation for Parkinson’s research examine how influenza infection interacts with alpha-synuclein misfolding and neuron to neuron transmission.
January 14, 2025 at 12:16 AM
Reposted by Yushan Wang
'The virus that causes COVID-19, known as SARS-CoV-2, may also make the brain vulnerable to Alzheimer's'.

It's very important to think through the population-level effects this will have in the next decade.

www.health.harvard.edu/mind-and-moo...
Are some cases of Alzheimer's disease caused by infection? - Harvard Health
Some scientists believe that microbes might play a part in Alzheimer's disease development. There are several theories about how and why this occurs. Microbes that might be involved include certain...
www.health.harvard.edu
January 13, 2025 at 4:48 PM
Why am I watching the House of Cards?
January 11, 2025 at 1:35 AM
Reposted by Yushan Wang
How tattoo ink induces inflammation and impairs the response to a Covid vaccine
www.biorxiv.org/content/10.1...
January 4, 2025 at 3:46 PM
Reposted by Yushan Wang
Cornell University researchers have found the pupil is key to understanding how, and when, the brain forms strong, long-lasting memories.

"Sleep microstructure organizes memory replay: Pupil size in sleep reveals how memories are sorted, preserved." #Nature

www.nature.com/articles/s41...
Sleep microstructure organizes memory replay - Nature
The temporal microstructure of the brain can multiplex distinct cognitive processes during sleep to support continuous learning.
www.nature.com
January 2, 2025 at 2:01 PM
Reposted by Yushan Wang
☕️💡 Can coffee slow aging?

A new review shows that moderate coffee consumption may extend healthspan, reducing risks of chronic diseases like cancer, cardiovascular issues, & memory loss.

This could add up to 2 years to your life.

🔗 www.sciencedirect.com/science/arti...

#SciComm #Coffee 🧪
Impact of coffee intake on human aging: Epidemiology and cellular mechanisms
The conception of coffee consumption has undergone a profound modification, evolving from a noxious habit into a safe lifestyle actually preserving hu…
www.sciencedirect.com
January 2, 2025 at 6:08 AM
Reposted by Yushan Wang
Albertans, please demand that your prov. govt. do everything they can to ensure Paxlovid is accessible. A bunch of us just had to call around to pharmacy after pharmacy to try and get some for a patient who needs it. She would have otherwise had to wait until Jan 2 - outside the window.
#abpoli
January 1, 2025 at 2:43 AM
Reposted by Yushan Wang
Does coffee prevent head and neck cancer?

"Coffee and tea consumption was linked with lower risks of developing head and neck cancers, including cancers of the mouth and throat."

Open Access
acsjournals.onlinelibrary.wiley.com/doi/full/10....
December 31, 2024 at 12:20 AM
Reposted by Yushan Wang
Original Article: Highly Pathogenic Avian Influenza A(H5N1) Virus Infections in Humans nej.md/3VU4R8I

Editorial: The Emerging Threat of H5N1 to Human Health nej.md/4fKc42s

Correspondence: Critical Illness in an Adolescent with Influenza A(H5N1) Virus Infection nej.md/4gR18Rt

#IDsky #MedSky
December 31, 2024 at 10:05 PM
Reposted by Yushan Wang
🧠 How COVID-19 impacts the brain

Researchers found that blood clots linked to COVID-19 can cause inflammation and brain damage.

A new antibody treatment targeting these clots could help reduce long-term effects seen in long COVID.

🔗 www.nature.com/articles/s41...

#SciComm #COVID19 🧪
Fibrin drives thromboinflammation and neuropathology in COVID-19 - Nature
Fibrin drives inflammation and neuropathology in SARS-CoV-2 infection, and fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with long COVID.
www.nature.com
December 31, 2024 at 11:43 AM
Reposted by Yushan Wang
Lifetime depression and poor sleep independently link to reduced brain structure, with poor sleep worsening depression's impact on certain areas.

by Lyall LM, Stolicyn A (...) Smith DJ et 6 al. in J Affect Disord #MedSky

📖 read the article:
Lifetime depression, sleep disruption and brain structure in the UK Biobank cohort
Whether depression and poor sleep interact or have statistically independent associations with brain structure and its change over time is not known. …
www.sciencedirect.com
December 31, 2024 at 12:49 PM
Reposted by Yushan Wang
XEC Variant May Be Driving ‘Silent’ COVID-19 Surge In December 2024.

"Not talking about COVID-19 doesn’t mean that it has gone away. The trouble, though, is many people are acting as if COVID has gone"

Source: archive.md/7mZaT
December 30, 2024 at 12:37 AM
Reposted by Yushan Wang
SARS-CoV-2 spike S1 protein affects the pancreas's islet microvascular function in humans. This can contribute to dysfunction in the pancreas and the development of diabetes following SARS-CoV-2 infection

#LongCovid
t.co/0Edr2EPdJf
https://diabetesjournals.org/diabetes/article/doi/10.2337/db24-0816/157642/SARS-CoV-2-Spike-S1-subunit-triggers-pericyte-and
t.co
December 26, 2024 at 10:04 PM
Reposted by Yushan Wang
Taxi and ambulance drivers exhibited the lowest Alzheimer's disease mortality rates among various occupations analyzed in the study.

by R Patel V, Liu M, Worsham CM and Jena AB in BMJ #MedSky

📖 read the article: https://www.bmj.com/content/387/bmj-2024-082194
December 26, 2024 at 4:32 AM
Reposted by Yushan Wang
Can flashing lights stall Alzheimer’s? What the science shows

Pulses of light and sound seem to have beneficial effects. But some argue it is too soon to market experimental devices.

www.nature.com/articles/d41...
Can flashing lights stall Alzheimer’s? What the science shows
Pulses of light and sound seem to have beneficial effects. But some argue it is too soon to market experimental devices.
www.nature.com
December 26, 2024 at 3:35 AM