Dr Elisa Perego
@elisaperego78.bsky.social
#LongCovid | researcher | Covid | infectious disease | health, disability, inequality in present and past | human-environment interactions | big data | medicine history | patient-led research | MA PHD| ≠ MD |
Communication & Media Studies
35%
Psychology
20%
Pinned
My new research is out
"A Case Definition of a New Disease: A Review of the US Working Definition (USG) and 2024 NASEM Definition for Long COVID"
I use two US #LongCovid case definitions as case studies for a broader discussion of SARS-CoV-2 sequelae
"A Case Definition of a New Disease: A Review of the US Working Definition (USG) and 2024 NASEM Definition for Long COVID"
I use two US #LongCovid case definitions as case studies for a broader discussion of SARS-CoV-2 sequelae
I can't express myself on the other things you mentioned such as nasal sprays as I have seen conflicting opinions on that and I am not an expert on that specific topic, but thanks for writing about masking
Not a problem:)
Airborne pathogens such as SARS-CoV-2 can spread and linger in the air, a bit like cigarette smoke. High quality masks/respirators are key to preventing infection, especially in indoor spaces.
"€500m to tackle ‘huge burden’ of long Covid and similar conditions"
Germany is set to fund a half a billion euros for research in post infectious diseases in the next ten years
It is my hope funding will go to critical biomedical research and trials
Germany is set to fund a half a billion euros for research in post infectious diseases in the next ten years
It is my hope funding will go to critical biomedical research and trials
There are obviously more publications available on the topic on repositories such as PubMED. I want to thank all those who intervened with other publications in the discussion/thread below the first paper I shared. Looking forward to more research on this very important issue
These are just some examples of publications, including in the top Science journal, which address the issue of immune dysfunction/dysregulation following SARS-CoV-2 infection. This is a topic that deserves the upmost attention in my opinion and I hope to see more research on it
Why scientists are rethinking the immune effects of SARS-CoV-2 (recognizing the immune system can be altered by SARS-CoV-2 infection). BMJ, 2025
Differential decline of SARS-CoV-2-specific antibody levels, innate and adaptive immune cells, and shift of Th1/inflammatory to Th2 serum cytokine levels long after first COVID-19
Kratzer et al 2024
Kratzer et al 2024
COVID-19 disease and immune dysregulation
Davitt et al 2022
Davitt et al 2022
Cruz, T., Albacar, N., Ruiz, E. et al. Persistence of dysfunctional immune response 12 months after SARS-CoV-2 infection and their relationship with pulmonary sequelae and long COVID. Respir Res 26, 152 (2025).
Lage SL, Bricker-Holt K, Rocco JM, Rupert A, Donovan FX, Abramzon YA, Chandrasekharappa SC, McNinch C, et al Persistent immune dysregulation and metabolic alterations following SARS-CoV-2 infection. medRxiv
Pérez-Gómez, A., Vitallé, J., Gasca-Capote, C. et al. Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection. Cell Mol Immunol 18, 2128–2139 (2021).
Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, et al. Longitudinal analyses reveal immunological misfiring in severe COVID-19. Nature. (2020) 584:463–9. doi: 10.1038/s41586-020-2588-y
For more research on immune dysfunction following SARS-CoV-2 infection including in acute and #LongCovid there are many papers you can look at. I add here some, which can also provide more references for you information. Of course, the literature is vast and you can look for more e.g. in PubMED
Progress on the pathway to long COVID treatments - Nature Immunology
The US National Institute of Allergy and Infectious Diseases and Foundation for the National Institutes of Health convened a 2-day workshop announcing four agents to enter RECOVER–Treating Long COVID ...
www.nature.com
This is the paper in question which is obviously one of many and recognized immune dysregulation in LC.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Why not to share the thread with the discussion and the papers including in Nat Rev Imm instead of the screenshot, so people can look up for said thread and papers for themselves. The first paper in the thread contains already a lot of bibliography whatever you can think of the paper as a whole
I have been answering you and other accounts in the thread multiple times and so have been others. Please be precise. Thanks.
We are keeping citing biomedical evidence of immune dysfunction following SARS-CoV-2 infection, including very recently from RECOVER in Nat Imm Review. If you are not willing to discuss this evidence, there is no point in continuing the discussion. Thanks for writing.
You might have your own views on the content of such papers and others contained in PubMED or the one in Nat Review Imm from RECOVER I just shared. However, if you want your opinions more widely known, I'd suggest you to write a review of your own or do a thread on these papers from your account
Which papers, Marc (if I may)? If I understand correctly you are commenting on a paper reviewing immune dysfunction following SARS-CoV-2 infection, which cites other papers on immune dysfunction including from the Nature portfolio, just to make an example/
Progress on the pathway to long COVID treatments - Nature Immunology
The US National Institute of Allergy and Infectious Diseases and Foundation for the National Institutes of Health convened a 2-day workshop announcing four agents to enter RECOVER–Treating Long COVID ...
www.nature.com
But there are, however, many papers on the topic and just to give an example Nature Review Immunology just wrote an article about RECOVER Treat Long Covid which notes immune dysregulation and persistent infection among potential drivers of LC.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
What do you mean? The scientific literature is available (as I mentioned for example in PubMED) and deserves attention
This is your opinion but here we have to debate the scientific and clinical evidence
In what sense it's misinformation
In PubMED for example
What do you mean?
Which misinformation?