Dr Elisa Perego
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elisaperego78.bsky.social
Dr Elisa Perego
@elisaperego78.bsky.social
#LongCovid | researcher | Covid | infectious disease | health, disability, inequality in present and past | human-environment interactions | big data | medicine history | patient-led research | MA PHD| ≠ MD |
I can't express myself on the other things you mentioned such as nasal sprays as I have seen conflicting opinions on that and I am not an expert on that specific topic, but thanks for writing about masking
November 19, 2025 at 12:57 AM
Not a problem:)
November 19, 2025 at 12:54 AM
Reposted by Dr Elisa Perego
For more research on immune dysfunction following SARS-CoV-2 infection including in acute and #LongCovid there are many papers you can look at. I add here some, which can also provide more references for you information. Of course, the literature is vast and you can look for more e.g. in PubMED
November 18, 2025 at 5:42 PM
There are obviously more publications available on the topic on repositories such as PubMED. I want to thank all those who intervened with other publications in the discussion/thread below the first paper I shared. Looking forward to more research on this very important issue
November 18, 2025 at 6:22 PM
These are just some examples of publications, including in the top Science journal, which address the issue of immune dysfunction/dysregulation following SARS-CoV-2 infection. This is a topic that deserves the upmost attention in my opinion and I hope to see more research on it
November 18, 2025 at 6:19 PM
Why scientists are rethinking the immune effects of SARS-CoV-2 (recognizing the immune system can be altered by SARS-CoV-2 infection). BMJ, 2025
November 18, 2025 at 6:10 PM
Differential decline of SARS-CoV-2-specific antibody levels, innate and adaptive immune cells, and shift of Th1/inflammatory to Th2 serum cytokine levels long after first COVID-19

Kratzer et al 2024
November 18, 2025 at 6:05 PM
COVID-19 disease and immune dysregulation

Davitt et al 2022
November 18, 2025 at 6:02 PM
Immune damage in Long Covid. Science

www.science.org/doi/10.1126/...
Immune damage in Long Covid
Links between the complement and coagulation systems could lead to Long Covid therapies
www.science.org
November 18, 2025 at 5:56 PM
Cruz, T., Albacar, N., Ruiz, E. et al. Persistence of dysfunctional immune response 12 months after SARS-CoV-2 infection and their relationship with pulmonary sequelae and long COVID. Respir Res 26, 152 (2025).
November 18, 2025 at 5:55 PM
Lage SL, Bricker-Holt K, Rocco JM, Rupert A, Donovan FX, Abramzon YA, Chandrasekharappa SC, McNinch C, et al Persistent immune dysregulation and metabolic alterations following SARS-CoV-2 infection. medRxiv
November 18, 2025 at 5:54 PM
Pérez-Gómez, A., Vitallé, J., Gasca-Capote, C. et al. Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection. Cell Mol Immunol 18, 2128–2139 (2021).
November 18, 2025 at 5:51 PM
Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, et al. Longitudinal analyses reveal immunological misfiring in severe COVID-19. Nature. (2020) 584:463–9. doi: 10.1038/s41586-020-2588-y
November 18, 2025 at 5:45 PM
For more research on immune dysfunction following SARS-CoV-2 infection including in acute and #LongCovid there are many papers you can look at. I add here some, which can also provide more references for you information. Of course, the literature is vast and you can look for more e.g. in PubMED
November 18, 2025 at 5:42 PM
This is the paper in question which is obviously one of many and recognized immune dysregulation in LC.

www.nature.com/articles/s41...
Progress on the pathway to long COVID treatments - Nature Immunology
The US National Institute of Allergy and Infectious Diseases and Foundation for the National Institutes of Health convened a 2-day workshop announcing four agents to enter RECOVER–Treating Long COVID ...
www.nature.com
November 18, 2025 at 5:37 PM
Why not to share the thread with the discussion and the papers including in Nat Rev Imm instead of the screenshot, so people can look up for said thread and papers for themselves. The first paper in the thread contains already a lot of bibliography whatever you can think of the paper as a whole
November 18, 2025 at 5:12 PM
I have been answering you and other accounts in the thread multiple times and so have been others. Please be precise. Thanks.
November 18, 2025 at 5:02 PM