Jens Wohlmann
@wohlmann.bsky.social
Interests: (Electron) Microscopy, cell biology, nature and outdoors. Some photography too.
Reposted by Jens Wohlmann
(1/n) DNA-PAINT imaging inside the nucleus at single antibody resolution using TIRF? Ultrathin sectioning makes it happen!
Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org!
doi.org/10.1073/pnas...
👇🧵
Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org!
doi.org/10.1073/pnas...
👇🧵
August 13, 2025 at 2:19 PM
(1/n) DNA-PAINT imaging inside the nucleus at single antibody resolution using TIRF? Ultrathin sectioning makes it happen!
Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org!
doi.org/10.1073/pnas...
👇🧵
Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org!
doi.org/10.1073/pnas...
👇🧵
Reposted by Jens Wohlmann
This is an image of a human immune cell called a macrophage (purple) connecting with the bacteria Mycobacterium tuberculosis (green), which causes TB. #microscopy 🧪🔬
Image credit: Tony Fearns and Beren Aylan
Image credit: Tony Fearns and Beren Aylan
February 25, 2025 at 1:15 PM
This is an image of a human immune cell called a macrophage (purple) connecting with the bacteria Mycobacterium tuberculosis (green), which causes TB. #microscopy 🧪🔬
Image credit: Tony Fearns and Beren Aylan
Image credit: Tony Fearns and Beren Aylan
Reposted by Jens Wohlmann
In the wake of Meta’s decision to remove its third-party fact-checking system and loosen content moderation policies, here's how to delete your Facebook, Instagram, and Threads accounts
How to delete Facebook, Instagram, and Threads | TechCrunch
In the wake of Meta’s decision to remove its third-party fact-checking system and loosen content moderation policies, Google searches on how to delete
tcrn.ch
January 10, 2025 at 9:04 PM
In the wake of Meta’s decision to remove its third-party fact-checking system and loosen content moderation policies, here's how to delete your Facebook, Instagram, and Threads accounts
Reposted by Jens Wohlmann
I fear there is deep truth here.
January 11, 2025 at 8:47 PM
I fear there is deep truth here.
Reposted by Jens Wohlmann
Still our favorite #review! Unfortunately, as relevant today as when it was published, it is an excellent illustration of the #problems arising from the neglect of #ultrastructure and #electronmicroscopy in #cell-biology and the over-reliance on #fluorescence #microscopy.
doi.org/10.1016/0962...
doi.org/10.1016/0962...
January 8, 2025 at 8:18 AM
Still our favorite #review! Unfortunately, as relevant today as when it was published, it is an excellent illustration of the #problems arising from the neglect of #ultrastructure and #electronmicroscopy in #cell-biology and the over-reliance on #fluorescence #microscopy.
doi.org/10.1016/0962...
doi.org/10.1016/0962...
Reposted by Jens Wohlmann
#Science in the age of #selfies
A short #opinion article that we think hits a very important point!
Albert #Einstein: “an academic career, in which a person is forced to produce #scientific writings in great amounts, creates a #danger of intellectual superficiality”
www.pnas.org/doi/10.1073/...
A short #opinion article that we think hits a very important point!
Albert #Einstein: “an academic career, in which a person is forced to produce #scientific writings in great amounts, creates a #danger of intellectual superficiality”
www.pnas.org/doi/10.1073/...
Science in the age of selfies | PNAS
Science in the age of selfies
www.pnas.org
January 6, 2025 at 7:35 AM
#Science in the age of #selfies
A short #opinion article that we think hits a very important point!
Albert #Einstein: “an academic career, in which a person is forced to produce #scientific writings in great amounts, creates a #danger of intellectual superficiality”
www.pnas.org/doi/10.1073/...
A short #opinion article that we think hits a very important point!
Albert #Einstein: “an academic career, in which a person is forced to produce #scientific writings in great amounts, creates a #danger of intellectual superficiality”
www.pnas.org/doi/10.1073/...
Reposted by Jens Wohlmann
Ants best humans at test of collective intelligence
"When people work together, they can achieve great things. But if they can’t talk, they’re not necessarily smarter than ants"
Original paper
www.pnas.org/doi/10.1073/...
News
www.science.org/content/arti...
"When people work together, they can achieve great things. But if they can’t talk, they’re not necessarily smarter than ants"
Original paper
www.pnas.org/doi/10.1073/...
News
www.science.org/content/arti...
January 5, 2025 at 9:41 AM
Ants best humans at test of collective intelligence
"When people work together, they can achieve great things. But if they can’t talk, they’re not necessarily smarter than ants"
Original paper
www.pnas.org/doi/10.1073/...
News
www.science.org/content/arti...
"When people work together, they can achieve great things. But if they can’t talk, they’re not necessarily smarter than ants"
Original paper
www.pnas.org/doi/10.1073/...
News
www.science.org/content/arti...
Reposted by Jens Wohlmann
Technically superb, live imaging experiments visualise intraflagellar transport in zebrafish ciliated tissues, unveil the surprising breadth of intraflagellar transport speed.
https://buff.ly/41UJjMS
https://buff.ly/41UJjMS
January 1, 2025 at 2:01 PM
Technically superb, live imaging experiments visualise intraflagellar transport in zebrafish ciliated tissues, unveil the surprising breadth of intraflagellar transport speed.
https://buff.ly/41UJjMS
https://buff.ly/41UJjMS
Reposted by Jens Wohlmann
snow under the electron microscope
January 2, 2025 at 3:41 PM
snow under the electron microscope
Reposted by Jens Wohlmann
sea cucumber skin under a microscope
January 2, 2025 at 7:28 PM
sea cucumber skin under a microscope
Reposted by Jens Wohlmann
We possess the technology to create products that nearly never break. We were doing it in the 70's & 80's.
Then came 'planned obsolescence' - intentionally designing products to become obsolete or break quickly within a set time frame.
This is that- but in reverse.
Then came 'planned obsolescence' - intentionally designing products to become obsolete or break quickly within a set time frame.
This is that- but in reverse.
Goldman Sachs asks in biotech research report: 'Is curing patients a sustainable business model?'
Goldman Sachs warns sales from the most successful disease treatments are difficult to maintain.
www.cnbc.com
January 2, 2025 at 7:45 PM
We possess the technology to create products that nearly never break. We were doing it in the 70's & 80's.
Then came 'planned obsolescence' - intentionally designing products to become obsolete or break quickly within a set time frame.
This is that- but in reverse.
Then came 'planned obsolescence' - intentionally designing products to become obsolete or break quickly within a set time frame.
This is that- but in reverse.
Reposted by Jens Wohlmann
the world's smallest christmas tree made from diatoms
December 24, 2024 at 3:46 PM
the world's smallest christmas tree made from diatoms
Reposted by Jens Wohlmann
At my institution, they want to install profiles on our personal phones that will give IT root level access to our personal phones.
And allow them to remotely wipe our phones. Our personal phones.
Damn straight, take your work email off your phone. And remove your work profiles from your phones.
And allow them to remotely wipe our phones. Our personal phones.
Damn straight, take your work email off your phone. And remove your work profiles from your phones.
Take your work email off your phone.
You’re welcome
You’re welcome
December 21, 2024 at 3:42 PM
At my institution, they want to install profiles on our personal phones that will give IT root level access to our personal phones.
And allow them to remotely wipe our phones. Our personal phones.
Damn straight, take your work email off your phone. And remove your work profiles from your phones.
And allow them to remotely wipe our phones. Our personal phones.
Damn straight, take your work email off your phone. And remove your work profiles from your phones.
Reposted by Jens Wohlmann
Instead of listing my publications, as the year draws to an end, I want to shine the spotlight on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research.
December 20, 2024 at 11:18 AM
Instead of listing my publications, as the year draws to an end, I want to shine the spotlight on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research.
Reposted by Jens Wohlmann
Discover how urban tree loss impacts education in cities, with new research from Chicago revealing surprising effects on students from low-income families.
Urban Trees' Role in Education: Insights from Chicago's Ash Borer Infestation
Discover how urban tree loss impacts education in cities, with new research from Chicago revealing surprising effects on students from low-income families.
www.science-tldr.com
December 18, 2024 at 6:16 PM
Discover how urban tree loss impacts education in cities, with new research from Chicago revealing surprising effects on students from low-income families.
Reposted by Jens Wohlmann
Das #pentaradio24 – Daten sind strukturierte Informationen, aber sind sie verlässlich? Bürokratien machen aus Menschen Datenpunkte. Was können wir tun, damit Daten wieder im Dienste der Menschen stehen? c3d2.de/news/pentara...
<<</>> Chaos Computer Club Dresden | C3D2pentaradio24: Was, wenn Daten eine schlechte Idee sind?
<<</>> C3D2, der Erfahrungsaustauschkreis aus Dresden
c3d2.de
December 17, 2024 at 9:56 AM
Das #pentaradio24 – Daten sind strukturierte Informationen, aber sind sie verlässlich? Bürokratien machen aus Menschen Datenpunkte. Was können wir tun, damit Daten wieder im Dienste der Menschen stehen? c3d2.de/news/pentara...
Reposted by Jens Wohlmann
We're very disappointed Let's Encrypt is ending support for proper revocation checks via OCSP Must-Staple which is the only efficient, private and secure method not depending on a browser-specific service:
letsencrypt.org/2024/12/05/e...
No replacement is being offered for the feature.
letsencrypt.org/2024/12/05/e...
No replacement is being offered for the feature.
Ending OCSP Support in 2025
Earlier this year we announced our intent to provide certificate revocation information exclusively via Certificate Revocation Lists (CRLs), ending support for providing certificate revocation informa...
letsencrypt.org
December 12, 2024 at 3:34 PM
We're very disappointed Let's Encrypt is ending support for proper revocation checks via OCSP Must-Staple which is the only efficient, private and secure method not depending on a browser-specific service:
letsencrypt.org/2024/12/05/e...
No replacement is being offered for the feature.
letsencrypt.org/2024/12/05/e...
No replacement is being offered for the feature.
Reposted by Jens Wohlmann
This is fascinating! Ticks form a "cement cone" from their saliva that glues them to you. Now we know more about the chemistry of that bioadhesive process 🧪 www.the-scientist.com/what-makes-a...
What Makes a Tick Stick?
Ticks form a stable structure around their mouth to stick to their hosts for days. Phase transitions of proteins in the tick saliva drive this adhesion.
www.the-scientist.com
December 15, 2024 at 3:56 PM
This is fascinating! Ticks form a "cement cone" from their saliva that glues them to you. Now we know more about the chemistry of that bioadhesive process 🧪 www.the-scientist.com/what-makes-a...
Reposted by Jens Wohlmann
Wideband laser speckle rheological microscopy reveals the viscoelastic landscape of biological tissues with high spatial resolution (25 micrometers) 👏
www.science.org/doi/10.1126/...
#Mechanobiology
www.science.org/doi/10.1126/...
#Mechanobiology
December 14, 2024 at 5:43 PM
Wideband laser speckle rheological microscopy reveals the viscoelastic landscape of biological tissues with high spatial resolution (25 micrometers) 👏
www.science.org/doi/10.1126/...
#Mechanobiology
www.science.org/doi/10.1126/...
#Mechanobiology
Reposted by Jens Wohlmann
This lab @tulanemedicine.bsky.social has 23 papers with @pubpeer.com comments and 7 retractions.
Yet, the Principal Investigator is still a professor at Tulane.
Is Tulane looking the other way, as long as the PI brings in the grants?
pubpeer.com/publications...
Yet, the Principal Investigator is still a professor at Tulane.
Is Tulane looking the other way, as long as the PI brings in the grants?
pubpeer.com/publications...
December 15, 2024 at 5:15 AM
This lab @tulanemedicine.bsky.social has 23 papers with @pubpeer.com comments and 7 retractions.
Yet, the Principal Investigator is still a professor at Tulane.
Is Tulane looking the other way, as long as the PI brings in the grants?
pubpeer.com/publications...
Yet, the Principal Investigator is still a professor at Tulane.
Is Tulane looking the other way, as long as the PI brings in the grants?
pubpeer.com/publications...
Reposted by Jens Wohlmann
I'm gonna piss a few nerds off but this is an example of why a lightsheet microscope should be used to study organoids. The detection optics are great for imaging in XY but they suck axially. Sure, yeah, hocus pocus, RI matching, correction collar, blah blah, but it's physics, baby.
December 14, 2024 at 3:19 PM
I'm gonna piss a few nerds off but this is an example of why a lightsheet microscope should be used to study organoids. The detection optics are great for imaging in XY but they suck axially. Sure, yeah, hocus pocus, RI matching, correction collar, blah blah, but it's physics, baby.
Reposted by Jens Wohlmann
The best science images of 2024 — Nature’s picks
www.nature.com/immersive/d4... 🧪
📷 close-up of the species Rhynchophorus ferrugineus, by Sherif Abdallah Ahmed/Nikon Small World Photomicrography Competition
www.nature.com/immersive/d4... 🧪
📷 close-up of the species Rhynchophorus ferrugineus, by Sherif Abdallah Ahmed/Nikon Small World Photomicrography Competition
December 13, 2024 at 7:28 PM
The best science images of 2024 — Nature’s picks
www.nature.com/immersive/d4... 🧪
📷 close-up of the species Rhynchophorus ferrugineus, by Sherif Abdallah Ahmed/Nikon Small World Photomicrography Competition
www.nature.com/immersive/d4... 🧪
📷 close-up of the species Rhynchophorus ferrugineus, by Sherif Abdallah Ahmed/Nikon Small World Photomicrography Competition
Reposted by Jens Wohlmann
“In this review, we discuss the main manifestations, immunological players, and risk factors of TB immunopathology and highlight opportunities for medical intervention.” #ImmunoSky 🩺🧪
Immunopathology in human tuberculosis
The balance between protective and pathological immune responses shapes progression of Mycobacterium tuberculosis infection.
www.science.org
December 13, 2024 at 9:25 PM
“In this review, we discuss the main manifestations, immunological players, and risk factors of TB immunopathology and highlight opportunities for medical intervention.” #ImmunoSky 🩺🧪
Reposted by Jens Wohlmann
Here’s another very interesting and common marine organism. They’re copepods, albeit, they look almost nothing like typical free-living copepods you may know.
This group starts as juveniles looking like most other copepods, but lose their limbs and antennae once they mature.
🦑🧪
This group starts as juveniles looking like most other copepods, but lose their limbs and antennae once they mature.
🦑🧪
December 14, 2024 at 6:39 AM
Here’s another very interesting and common marine organism. They’re copepods, albeit, they look almost nothing like typical free-living copepods you may know.
This group starts as juveniles looking like most other copepods, but lose their limbs and antennae once they mature.
🦑🧪
This group starts as juveniles looking like most other copepods, but lose their limbs and antennae once they mature.
🦑🧪