William Brett
@w-noah-brett.bsky.social
PhD student, Stony Brook University, Molecular and Cellular Pharmacology
Disciple of science, ciliophile, snowboarder,tinkerer
Disciple of science, ciliophile, snowboarder,tinkerer
Reposted by William Brett
Genetics peeps: Looking for cool new software to do genetic sequence variation analysis in biiiiig databases?
Check it.
Check it.
We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.
1/n
1/n
Intro to Bedder – The Quinlan Lab
quinlanlab.org
December 2, 2025 at 4:42 AM
Genetics peeps: Looking for cool new software to do genetic sequence variation analysis in biiiiig databases?
Check it.
Check it.
Reposted by William Brett
Hearing a rumor that NIH/HHS may now plan to retaliate against other Bethesda Declaration signers.
I am one, but it’s not about me: we have been speaking out because of the ongoing damage to US medical research, cancer and Alzheimer’s research.
As @jenna-m-norton.bsky.social put well: 1/
I am one, but it’s not about me: we have been speaking out because of the ongoing damage to US medical research, cancer and Alzheimer’s research.
As @jenna-m-norton.bsky.social put well: 1/
November 14, 2025 at 4:17 PM
Hearing a rumor that NIH/HHS may now plan to retaliate against other Bethesda Declaration signers.
I am one, but it’s not about me: we have been speaking out because of the ongoing damage to US medical research, cancer and Alzheimer’s research.
As @jenna-m-norton.bsky.social put well: 1/
I am one, but it’s not about me: we have been speaking out because of the ongoing damage to US medical research, cancer and Alzheimer’s research.
As @jenna-m-norton.bsky.social put well: 1/
Reposted by William Brett
I just walked out of federal court where I pleaded NOT GUILTY to the charges against me.
I will continue to stand up to authoritarianism and call this out for what it is: a political prosecution.
I will continue to stand up to authoritarianism and call this out for what it is: a political prosecution.
November 12, 2025 at 9:05 PM
I just walked out of federal court where I pleaded NOT GUILTY to the charges against me.
I will continue to stand up to authoritarianism and call this out for what it is: a political prosecution.
I will continue to stand up to authoritarianism and call this out for what it is: a political prosecution.
Reposted by William Brett
This is so offensive I don’t even know where to start.
“Vote blue no matter who and also shut the fuck up when those people betray you.”
Nope.
We will primary every senator who doesn’t call for Schumer to step down in the next 24 hours.
You work for us.
“Vote blue no matter who and also shut the fuck up when those people betray you.”
Nope.
We will primary every senator who doesn’t call for Schumer to step down in the next 24 hours.
You work for us.
The sooner we get past internal recriminations and back to fighting united, the better off we all are — the likelier our victory next November.
November 11, 2025 at 12:19 AM
This is so offensive I don’t even know where to start.
“Vote blue no matter who and also shut the fuck up when those people betray you.”
Nope.
We will primary every senator who doesn’t call for Schumer to step down in the next 24 hours.
You work for us.
“Vote blue no matter who and also shut the fuck up when those people betray you.”
Nope.
We will primary every senator who doesn’t call for Schumer to step down in the next 24 hours.
You work for us.
Reposted by William Brett
Come on! We know members of the Senate are “free agents,” but the fact is Schumer didn’t hold his caucus together & isn’t doing his job as Leader
We’re supposed to believe it’s a coincidence that none of the Dems who voted yes on the CR have anything to lose in 2026?
@schumer.senate.gov STEP DOWN!
We’re supposed to believe it’s a coincidence that none of the Dems who voted yes on the CR have anything to lose in 2026?
@schumer.senate.gov STEP DOWN!
November 10, 2025 at 6:32 PM
Come on! We know members of the Senate are “free agents,” but the fact is Schumer didn’t hold his caucus together & isn’t doing his job as Leader
We’re supposed to believe it’s a coincidence that none of the Dems who voted yes on the CR have anything to lose in 2026?
@schumer.senate.gov STEP DOWN!
We’re supposed to believe it’s a coincidence that none of the Dems who voted yes on the CR have anything to lose in 2026?
@schumer.senate.gov STEP DOWN!
Reposted by William Brett
Chuck Schumer Helps Pull Democrats Back From Brink Of Courage
November 10, 2025 at 5:02 AM
Chuck Schumer Helps Pull Democrats Back From Brink Of Courage
Reposted by William Brett
Voters want a Democratic Party that fights back against the forces that have rigged the system and made their lives more difficult.
A party that comforts the afflicted and afflicts the comfortable —not a party that buckles and capitulates.
When will party leadership learn this lesson?
A party that comforts the afflicted and afflicts the comfortable —not a party that buckles and capitulates.
When will party leadership learn this lesson?
November 10, 2025 at 10:45 PM
Voters want a Democratic Party that fights back against the forces that have rigged the system and made their lives more difficult.
A party that comforts the afflicted and afflicts the comfortable —not a party that buckles and capitulates.
When will party leadership learn this lesson?
A party that comforts the afflicted and afflicts the comfortable —not a party that buckles and capitulates.
When will party leadership learn this lesson?
Reposted by William Brett
In response to this claim that the "strategy didn't work."
The people were on our side. We were building momentum to help save our democracy. We could have won - the premium increase notices were just starting.
And giving in now will embolden him. Things will likely get worse.
The people were on our side. We were building momentum to help save our democracy. We could have won - the premium increase notices were just starting.
And giving in now will embolden him. Things will likely get worse.
November 10, 2025 at 5:43 PM
In response to this claim that the "strategy didn't work."
The people were on our side. We were building momentum to help save our democracy. We could have won - the premium increase notices were just starting.
And giving in now will embolden him. Things will likely get worse.
The people were on our side. We were building momentum to help save our democracy. We could have won - the premium increase notices were just starting.
And giving in now will embolden him. Things will likely get worse.
Reposted by William Brett
“We kept @schumer.senate.gov informed throughout”
Translation: Schumer quarterbacked it and made sure only Dems not up for re-election voted to cave
Translation: Schumer quarterbacked it and made sure only Dems not up for re-election voted to cave
November 10, 2025 at 2:52 PM
“We kept @schumer.senate.gov informed throughout”
Translation: Schumer quarterbacked it and made sure only Dems not up for re-election voted to cave
Translation: Schumer quarterbacked it and made sure only Dems not up for re-election voted to cave
Reposted by William Brett
Tonight’s dumb napkin cartoon…
November 10, 2025 at 2:45 AM
Tonight’s dumb napkin cartoon…
Reposted by William Brett
getting two pinky swears from Republicans, including one that they will merely follow the law, is laughably thin gruel
My statement on the funding deal to reopen government, protect federal employees, and vote to protect health care:
November 10, 2025 at 1:19 AM
getting two pinky swears from Republicans, including one that they will merely follow the law, is laughably thin gruel
Reposted by William Brett
The 8 Dems who surrendered: @SenAngusKing @timkaine @SenCortezMasto @JohnFetterman @SenatorDurbin @SenatorHassan @SenatorShaheen @SenJackyRosen
November 10, 2025 at 3:12 AM
The 8 Dems who surrendered: @SenAngusKing @timkaine @SenCortezMasto @JohnFetterman @SenatorDurbin @SenatorHassan @SenatorShaheen @SenJackyRosen
Reposted by William Brett
Never forget who sold us out:
Hassan
King
Cortez-Masto
Shaheen
Kaine
Fetterman
Durbin
Rosen
Hassan
King
Cortez-Masto
Shaheen
Kaine
Fetterman
Durbin
Rosen
November 10, 2025 at 2:26 AM
Never forget who sold us out:
Hassan
King
Cortez-Masto
Shaheen
Kaine
Fetterman
Durbin
Rosen
Hassan
King
Cortez-Masto
Shaheen
Kaine
Fetterman
Durbin
Rosen
Reposted by William Brett
Fuck these traitors. Primary their sorry asses.
November 10, 2025 at 2:33 AM
Fuck these traitors. Primary their sorry asses.
Reposted by William Brett
Senators on the brink of retirement who lived full, wealthy lives and never feared the loss of their own healthcare voting for their constituents to die from their inability to afford the same is treasonous
November 10, 2025 at 2:20 AM
Senators on the brink of retirement who lived full, wealthy lives and never feared the loss of their own healthcare voting for their constituents to die from their inability to afford the same is treasonous
Reposted by William Brett
This right here.
Chris Murphy: "There will be pretty substantial damage to a Dem brand that has been rehabilitated if on the heels of an election in which the people told us to keep fighting, we immediately stop... if we surrender without having gotten anything, I worry it'll be hard to get them back up off the mat"
November 10, 2025 at 1:23 AM
This right here.
Reposted by William Brett
The Python Software Foundation was recommended for a $1.5M grant from the National Science Foundation. The terms of the award said PSF could not work on DEI, whether or not the grant funding was used for it.
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
TLDR; The PSF has made the decision to put our community and our shared diversity, equity, and inclusion values ahead of seeking $1.5M in new revenue. Please read and share. pyfound.blogspot.com/2025/10/NSF-...
🧵
🧵
The official home of the Python Programming Language
www.python.org
October 27, 2025 at 5:31 PM
The Python Software Foundation was recommended for a $1.5M grant from the National Science Foundation. The terms of the award said PSF could not work on DEI, whether or not the grant funding was used for it.
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
PSF therefore declined the funding.
Science suffers, but commitment to core values remains
Reposted by William Brett
Inside the Hermitage, the winter palace where Tsar Nicholas II and his family lived before they were executed—in a country where Russians were starving.
October 23, 2025 at 1:50 PM
Inside the Hermitage, the winter palace where Tsar Nicholas II and his family lived before they were executed—in a country where Russians were starving.
Reposted by William Brett
Thanks to @insidehighered.com for publishing my perspective about being reprimanded by the Gordon Research conference after my display of empathy for Palestinian victims of genocide.
www.insidehighered.com/opinion/view...
www.insidehighered.com/opinion/view...
The Palestine Exception in Science (opinion)
A small act in recognition of Palestinian humanity during a scientific presentation should not have been met with a reprimand.
www.insidehighered.com
October 24, 2025 at 12:35 PM
Thanks to @insidehighered.com for publishing my perspective about being reprimanded by the Gordon Research conference after my display of empathy for Palestinian victims of genocide.
www.insidehighered.com/opinion/view...
www.insidehighered.com/opinion/view...
Reposted by William Brett
Just disgusting.
October 23, 2025 at 2:40 PM
Just disgusting.
Reposted by William Brett
Warped priorities: 17 NYT news stories on the Louvre jewel heist (so far); 3 NYT news stories on 7 MILLION PEOPLE attending No KIngs Day events (including one on late-night comedians and one on Trump's "brown liquid" video.)
October 22, 2025 at 12:25 PM
Warped priorities: 17 NYT news stories on the Louvre jewel heist (so far); 3 NYT news stories on 7 MILLION PEOPLE attending No KIngs Day events (including one on late-night comedians and one on Trump's "brown liquid" video.)
Reposted by William Brett
You might have noticed lots of activity in the napari project recently! 🚀 We're grateful for a grant from CZI that's keeping us going, but grants don't last forever: we're trying to figure out sustainable long term funding. Read our blog post to find out how you can help:
napari.org/island-dispa...
napari.org/island-dispa...
October 21, 2025 at 2:32 PM
You might have noticed lots of activity in the napari project recently! 🚀 We're grateful for a grant from CZI that's keeping us going, but grants don't last forever: we're trying to figure out sustainable long term funding. Read our blog post to find out how you can help:
napari.org/island-dispa...
napari.org/island-dispa...
Reposted by William Brett
😶
From the Chronicle daily briefing, Vanderbilt and Wash U. continue to show themselves as authoritarianism curious.
October 22, 2025 at 3:24 AM
😶
Reposted by William Brett
