Tony
@tonysurvivor.bsky.social
Recipient of 2 kidney grafts, years of dialysis, and long covid. Life's a bitch but that bitch is mine.
Microneurography Reveals Unmyelinated Small Nerve Fiber Dysfunction in Long COVID - Ribeiro - Annals of Neurology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
Microneurography Reveals Unmyelinated Small Nerve Fiber Dysfunction in Long COVID
Objective To review the microneurography findings of long coronavirus disease 2019 (COVID) patients who presented to the clinic with multisystem involvement affecting neurological, cardiovascular, g...
onlinelibrary.wiley.com
September 23, 2025 at 8:02 PM
Microneurography Reveals Unmyelinated Small Nerve Fiber Dysfunction in Long COVID - Ribeiro - Annals of Neurology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Tony
Spain-based study of 69 post-COVID patients finds high levels of AT1 receptor autoantibodies and neurofilament light chain in blood and CSF, linking immune dysregulation with neuroaxonal damage and cognitive symptoms like brain fog.
www.frontiersin.org/journals/imm...
www.frontiersin.org/journals/imm...
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
www.frontiersin.org
April 22, 2025 at 5:41 PM
Spain-based study of 69 post-COVID patients finds high levels of AT1 receptor autoantibodies and neurofilament light chain in blood and CSF, linking immune dysregulation with neuroaxonal damage and cognitive symptoms like brain fog.
www.frontiersin.org/journals/imm...
www.frontiersin.org/journals/imm...
Reposted by Tony
At UC Davis and Johns Hopkins, researchers found that B cells in the lungs produce acetylcholine to suppress inflammation during flu infection.
These B cells limit macrophage-driven TNF responses, balancing viral control with tissue protection.
www.nature.com/articles/s41...
These B cells limit macrophage-driven TNF responses, balancing viral control with tissue protection.
www.nature.com/articles/s41...
B cells modulate lung antiviral inflammatory responses via the neurotransmitter acetylcholine - Nature Immunology
Cembellin-Prieto and colleagues find that B cells in the lung are capable of producing acetylcholine and that these regulate early macrophage activation and control influenza virus replication.
www.nature.com
April 22, 2025 at 5:53 PM
At UC Davis and Johns Hopkins, researchers found that B cells in the lungs produce acetylcholine to suppress inflammation during flu infection.
These B cells limit macrophage-driven TNF responses, balancing viral control with tissue protection.
www.nature.com/articles/s41...
These B cells limit macrophage-driven TNF responses, balancing viral control with tissue protection.
www.nature.com/articles/s41...
Reposted by Tony
Study finds that Non-DNMT3A CHIP was associated with CKD progression among individuals with CKD, and Tet2-CHIP mouse models support a causal role in kidney injury. https://bit.ly/JASN0680
@drflashheart.bsky.social
@pnatarajanmd.bsky.social
@zhiyu.bsky.social
#ASNJASN
@drflashheart.bsky.social
@pnatarajanmd.bsky.social
@zhiyu.bsky.social
#ASNJASN
April 22, 2025 at 2:00 PM
Study finds that Non-DNMT3A CHIP was associated with CKD progression among individuals with CKD, and Tet2-CHIP mouse models support a causal role in kidney injury. https://bit.ly/JASN0680
@drflashheart.bsky.social
@pnatarajanmd.bsky.social
@zhiyu.bsky.social
#ASNJASN
@drflashheart.bsky.social
@pnatarajanmd.bsky.social
@zhiyu.bsky.social
#ASNJASN
Reposted by Tony
GOOD NEWS! Researchers at the University of Buffalo have developed a nanoparticle-based vaccine candidate for H5N1 avian influenza (clade 2.3.4.4b) that achieved 100% PROTECTION in preclinical trials. The vaccine is under development for potential use in BOTH veterinary AND human medicine. 🧪🧵⬇️
April 22, 2025 at 4:00 PM
GOOD NEWS! Researchers at the University of Buffalo have developed a nanoparticle-based vaccine candidate for H5N1 avian influenza (clade 2.3.4.4b) that achieved 100% PROTECTION in preclinical trials. The vaccine is under development for potential use in BOTH veterinary AND human medicine. 🧪🧵⬇️
Reposted by Tony
Reposted by Tony
New large study indicates vaccines protective against long COVID www.cidrap.umn.edu/covid-19/new...
New large study indicates vaccines protective against long COVID
www.cidrap.umn.edu
February 6, 2025 at 8:29 PM
New large study indicates vaccines protective against long COVID www.cidrap.umn.edu/covid-19/new...
Reposted by Tony
A study compared the renoprotective benefits of metabolic surgery to GLP-1RA in obesity and CKD. #kidneydisease #nephsky #nephrology #metabolicsurgery #GLP1RA
Kidney-Protection Benefits of Metabolic Surgery Versus GLP1-RA in Patients With CKD | Docwire News
A study assessed the kidney benefits of metabolic surgery compared to glucagon-like peptide-1 receptor agonist treatment in patients with obesity and chronic kidney disease (CKD).
buff.ly
February 10, 2025 at 6:00 PM
A study compared the renoprotective benefits of metabolic surgery to GLP-1RA in obesity and CKD. #kidneydisease #nephsky #nephrology #metabolicsurgery #GLP1RA
Reposted by Tony
UK Covid Inquiry resumes next week.
Link to attend in thread.
#ClinicallyVulnerable
#Children #Teachers #Vaccines #Therapeutics
#LeaveNobodyBehind
Link to attend in thread.
#ClinicallyVulnerable
#Children #Teachers #Vaccines #Therapeutics
#LeaveNobodyBehind
🚨 The Covid Inquiry restarts next week.
It will be focused on a new topic of 'Vaccines and Therapeutics'.
This module is not getting the attention it deserves with only 3 wks and so MANY important witnesses.
1/
It will be focused on a new topic of 'Vaccines and Therapeutics'.
This module is not getting the attention it deserves with only 3 wks and so MANY important witnesses.
1/
January 9, 2025 at 8:42 PM
UK Covid Inquiry resumes next week.
Link to attend in thread.
#ClinicallyVulnerable
#Children #Teachers #Vaccines #Therapeutics
#LeaveNobodyBehind
Link to attend in thread.
#ClinicallyVulnerable
#Children #Teachers #Vaccines #Therapeutics
#LeaveNobodyBehind
Reposted by Tony
TOP 8: RaDaR by Drs. by Wong, Gale et al.
www.thelancet.com/journals/lan...
Compared to the general CKD population, patients with rare kidney diseases have a higher kidney failure risk.
Watch our webinar with Prof. Gale!
youtu.be/xxZStOn39No?...
www.thelancet.com/journals/lan...
Compared to the general CKD population, patients with rare kidney diseases have a higher kidney failure risk.
Watch our webinar with Prof. Gale!
youtu.be/xxZStOn39No?...
January 8, 2025 at 8:45 PM
TOP 8: RaDaR by Drs. by Wong, Gale et al.
www.thelancet.com/journals/lan...
Compared to the general CKD population, patients with rare kidney diseases have a higher kidney failure risk.
Watch our webinar with Prof. Gale!
youtu.be/xxZStOn39No?...
www.thelancet.com/journals/lan...
Compared to the general CKD population, patients with rare kidney diseases have a higher kidney failure risk.
Watch our webinar with Prof. Gale!
youtu.be/xxZStOn39No?...
Reposted by Tony
The nephrology community is on the cusp of a transformative era. With these advancements, 2025 promises a future where kidney care is more personalized, effective, and accessible, bringing hope to millions of patients worldwide. dailyhemo.blogspot.com/2025/01/2025... #dialysis #RenalSky
2025 Nephrology Forecast
Kidney disease news, awareness, and advocacy.
dailyhemo.blogspot.com
January 5, 2025 at 12:12 AM
The nephrology community is on the cusp of a transformative era. With these advancements, 2025 promises a future where kidney care is more personalized, effective, and accessible, bringing hope to millions of patients worldwide. dailyhemo.blogspot.com/2025/01/2025... #dialysis #RenalSky
Reposted by Tony
A golden year of innovative kidney disease therapeutics | Nature Reviews Nephrology - goo.gl/alerts/8t8q2B #GoogleAlerts
A golden year of innovative kidney disease therapeutics - Nature Reviews Nephrology
In 2024, a plethora of novel therapeutic strategies for kidney disease progressed to clinical trials, including an RNA interference therapeutic, a glucagon-like peptide 1 receptor agonist, a soluble g...
goo.gl
January 4, 2025 at 2:13 AM
A golden year of innovative kidney disease therapeutics | Nature Reviews Nephrology - goo.gl/alerts/8t8q2B #GoogleAlerts
Reposted by Tony
A randomized controlled trial evaluated the efficacy and safety of #apixaban for prevention of recurrent thrombosis after #thrombectomy of #hemodialysis #vascularaccess
doi.org/10.1016/j.kint.2024.10.023
#MedSky #NephSky #SkyNeph
doi.org/10.1016/j.kint.2024.10.023
#MedSky #NephSky #SkyNeph
December 30, 2024 at 6:32 PM
A randomized controlled trial evaluated the efficacy and safety of #apixaban for prevention of recurrent thrombosis after #thrombectomy of #hemodialysis #vascularaccess
doi.org/10.1016/j.kint.2024.10.023
#MedSky #NephSky #SkyNeph
doi.org/10.1016/j.kint.2024.10.023
#MedSky #NephSky #SkyNeph
Reposted by Tony
Leuven has done it again ☺️
Automated Urinary Chemokine Assays for Noninvasive Detection of Kidney Transplant Rejection: A Prospective Cohort Study
https://bit.ly/4fhzX0U #OpenAccess
https://bit.ly/4fhzX0U #OpenAccess
December 29, 2024 at 8:28 AM
Leuven has done it again ☺️
Reposted by Tony
What happens in China never just stays in China. There is a surge in influenza A in the U.S. as well this winter. We rarely test whether the virus is conventional flu, or H1N1 swine flu, H5N1 bird flu. But the crowded ERs seen in many places are indications something is afoot. 🧵
December 29, 2024 at 1:27 PM
What happens in China never just stays in China. There is a surge in influenza A in the U.S. as well this winter. We rarely test whether the virus is conventional flu, or H1N1 swine flu, H5N1 bird flu. But the crowded ERs seen in many places are indications something is afoot. 🧵
Reposted by Tony
mRNA vaccines, particularly mRNA1273, showed the greatest relative increase in side effects, while protein-based NVX-CoV2373 generally elicited similar reactogenicity to MenACWY.
Why? In my personal opinion, the mRNA vaccines contain a relatively high amount of RNA.
4/6
Why? In my personal opinion, the mRNA vaccines contain a relatively high amount of RNA.
4/6
December 29, 2024 at 1:46 PM
mRNA vaccines, particularly mRNA1273, showed the greatest relative increase in side effects, while protein-based NVX-CoV2373 generally elicited similar reactogenicity to MenACWY.
Why? In my personal opinion, the mRNA vaccines contain a relatively high amount of RNA.
4/6
Why? In my personal opinion, the mRNA vaccines contain a relatively high amount of RNA.
4/6
Reposted by Tony
🦠 | El covid persistente, sin respuesta cinco años después: "Aún no sabemos si recuperaremos nuestras vidas"
✍️ Beatriz Pérez
✍️ Beatriz Pérez
El covid persistente, sin respuesta cinco años después: 'Aún no sabemos si recuperaremos nuestras vidas'
Dos pacientes que contrajeron esta enfermedad en la primera ola explican cómo han cambiado sus vidas y reclaman más investigación, mejores diagnósticos y un registro de enfermos
s.mtrbio.com
December 27, 2024 at 4:10 PM
🦠 | El covid persistente, sin respuesta cinco años después: "Aún no sabemos si recuperaremos nuestras vidas"
✍️ Beatriz Pérez
✍️ Beatriz Pérez
Reposted by Tony
Belatacept, Bortezomib Battlestar Galactica -- novel agents in transplantation @ssfarouk @KidneyNews
December 12, 2024 at 2:07 AM
Belatacept, Bortezomib Battlestar Galactica -- novel agents in transplantation @ssfarouk @KidneyNews
Reposted by Tony
In patients whose immunosuppression regimen was changed from a CNI-based regimen to Belatacept:
- 5% incidence of TCMR and 1% AMR.
- Most TCMR was early after conversion <6 months.
- Seems less frequent than with DeNovo use.
t.co/vK3tgzk9xR
- 5% incidence of TCMR and 1% AMR.
- Most TCMR was early after conversion <6 months.
- Seems less frequent than with DeNovo use.
t.co/vK3tgzk9xR
https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2024.13544/full
t.co
December 11, 2024 at 2:04 AM
In patients whose immunosuppression regimen was changed from a CNI-based regimen to Belatacept:
- 5% incidence of TCMR and 1% AMR.
- Most TCMR was early after conversion <6 months.
- Seems less frequent than with DeNovo use.
t.co/vK3tgzk9xR
- 5% incidence of TCMR and 1% AMR.
- Most TCMR was early after conversion <6 months.
- Seems less frequent than with DeNovo use.
t.co/vK3tgzk9xR
Reposted by Tony
Early conversion to belatacept after renal transplantation http://onlinelibrary.wiley.com/doi/10.1111/ctr.12951/full @vinaynairdo
December 9, 2024 at 8:47 PM
Early conversion to belatacept after renal transplantation http://onlinelibrary.wiley.com/doi/10.1111/ctr.12951/full @vinaynairdo
Reposted by Tony
There's a recall of some batches of anti-rejection medications for organ transplant recipients. Some of the capsules are empty. Someone I know was NOT notified by their pharmacy as they claim to have not received the recall info yet. Please share. #news #health 🥽🧪🍎
www.fda.gov/safety/recal...
www.fda.gov/safety/recal...
Astellas Pharma US, Inc. Issues Voluntary Nationwide Recall of One Lot of PROGRAF® 0.5mg (Tacrolimus) and One Lot of ASTAGRAF XL® 0.5mg (Tacrolimus Extended-Release Capsules) Because Bottles Shipped t...
Astellas Pharma US, Inc. (Head of US Commercial: Michael Petroutsas, "Astellas") is voluntarily recalling one lot of PROGRAF® 0.5mg (tacrolimus) and one lot of ASTAGRAF XL® 0.5mg (tacrolimus extended-...
www.fda.gov
December 26, 2024 at 10:36 PM
There's a recall of some batches of anti-rejection medications for organ transplant recipients. Some of the capsules are empty. Someone I know was NOT notified by their pharmacy as they claim to have not received the recall info yet. Please share. #news #health 🥽🧪🍎
www.fda.gov/safety/recal...
www.fda.gov/safety/recal...
Reposted by Tony
#MedSky🧪 #IDSky #ImmunoSky #publichealth @jidjournal.bsky.social Immunocompromised patients are at increased risk of persistent #COVID infection with prolonged viral shedding for weeks after initial diagnosis . A small number of cases of occult #COVID19 have been reported .
December 26, 2024 at 5:15 AM
#MedSky🧪 #IDSky #ImmunoSky #publichealth @jidjournal.bsky.social Immunocompromised patients are at increased risk of persistent #COVID infection with prolonged viral shedding for weeks after initial diagnosis . A small number of cases of occult #COVID19 have been reported .
Reposted by Tony
Another in-human pig kidney xenotransplantation
After Boston, it’s back to @nyunephro.bsky.social
www.npr.org/sections/sho...
#NephSky
After Boston, it’s back to @nyunephro.bsky.social
www.npr.org/sections/sho...
#NephSky
A transplanted pig kidney offers a grandmother hope for life without dialysis
The patient was in kidney failure and her immune system would reject a human organ. Scientists hope genetically modified pig organs prove safe and will alleviate the organ shortage and save lives.
www.npr.org
December 17, 2024 at 3:09 PM
Another in-human pig kidney xenotransplantation
After Boston, it’s back to @nyunephro.bsky.social
www.npr.org/sections/sho...
#NephSky
After Boston, it’s back to @nyunephro.bsky.social
www.npr.org/sections/sho...
#NephSky