Faheem Farooq
@thelosttad.bsky.social
A Junior Researcher trying to map genome organization across Central Nervous System development | Aspiring PhD student.
Interested in all things regarding genome organization and regulation.
Interested in all things regarding genome organization and regulation.
Reposted by Faheem Farooq
George Orwell was only 42 years off with his book.
“Perhaps one did not want to be loved so much as to be understood.”
m.economictimes.com/magazines/pa...
“Perhaps one did not want to be loved so much as to be understood.”
m.economictimes.com/magazines/pa...
Quote of the day from George Orwell’s classic novel 1984: 'Perhaps one did not want to be loved so much as to be understood'
George Orwells famous line from 1984 about wanting to be understood more than loved becomes a lens to explore modern loneliness, work culture, and the hunger for genuine recognition. Tracing Winston S...
m.economictimes.com
January 17, 2026 at 12:09 PM
George Orwell was only 42 years off with his book.
“Perhaps one did not want to be loved so much as to be understood.”
m.economictimes.com/magazines/pa...
“Perhaps one did not want to be loved so much as to be understood.”
m.economictimes.com/magazines/pa...
Reposted by Faheem Farooq
This is great. More please! The more folk who rely on LLMs for funding planning means my chances go up even before I submit!
November 30, 2025 at 5:54 PM
This is great. More please! The more folk who rely on LLMs for funding planning means my chances go up even before I submit!
That's some cool stuff
Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....
August 8, 2025 at 7:12 AM
That's some cool stuff
Reposted by Faheem Farooq
Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....
August 7, 2025 at 4:20 PM
Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....
Reposted by Faheem Farooq
A 6-year long study from the Lab is finally out @genomeresearch.bsky.social
Mastered by @annanordin.bsky.social in collaboration with Chaitali Chakraborty from @remeseiro-lab.bsky.social
Why is our work Important? Discover it in the quick Bluetorial 👇
genome.cshlp.org/content/earl...
Mastered by @annanordin.bsky.social in collaboration with Chaitali Chakraborty from @remeseiro-lab.bsky.social
Why is our work Important? Discover it in the quick Bluetorial 👇
genome.cshlp.org/content/earl...
Wnt signaling activation induces CTCF binding and loop formation at cis-regulatory elements of target genes
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
genome.cshlp.org
July 15, 2025 at 7:58 AM
A 6-year long study from the Lab is finally out @genomeresearch.bsky.social
Mastered by @annanordin.bsky.social in collaboration with Chaitali Chakraborty from @remeseiro-lab.bsky.social
Why is our work Important? Discover it in the quick Bluetorial 👇
genome.cshlp.org/content/earl...
Mastered by @annanordin.bsky.social in collaboration with Chaitali Chakraborty from @remeseiro-lab.bsky.social
Why is our work Important? Discover it in the quick Bluetorial 👇
genome.cshlp.org/content/earl...
Reposted by Faheem Farooq
Do et al., 2025. Binding domain mutations provide insight into CTCF’s relationship with chromatin and its contribution to gene regulation www.cell.com/cell-genomic...
March 23, 2025 at 7:55 AM
Do et al., 2025. Binding domain mutations provide insight into CTCF’s relationship with chromatin and its contribution to gene regulation www.cell.com/cell-genomic...
Reposted by Faheem Farooq
Danio derives from the Bengali word “Dhani,” which translates to “of the rice fields.” #ZebrafishFunFacts 🧪
March 15, 2025 at 5:25 PM
Danio derives from the Bengali word “Dhani,” which translates to “of the rice fields.” #ZebrafishFunFacts 🧪
Reposted by Faheem Farooq
Our study on how TAD boundaries actively influence the neighboring domains published today in @pnas.org: www.pnas.org/doi/10.1073/...
Exciting outcomes from this interdisciplinary genomics/biophysical modeling strategy. See the thread for the BioRxiv preprint for a summary of highlights.
Exciting outcomes from this interdisciplinary genomics/biophysical modeling strategy. See the thread for the BioRxiv preprint for a summary of highlights.
March 10, 2025 at 10:07 PM
Our study on how TAD boundaries actively influence the neighboring domains published today in @pnas.org: www.pnas.org/doi/10.1073/...
Exciting outcomes from this interdisciplinary genomics/biophysical modeling strategy. See the thread for the BioRxiv preprint for a summary of highlights.
Exciting outcomes from this interdisciplinary genomics/biophysical modeling strategy. See the thread for the BioRxiv preprint for a summary of highlights.
Maybe USA will finally have lower incidence of cardiovascular disease when Trump finds out about trans fats and bans it
#StandUpForScience
#StandUpForScience
March 8, 2025 at 10:19 AM
Maybe USA will finally have lower incidence of cardiovascular disease when Trump finds out about trans fats and bans it
#StandUpForScience
#StandUpForScience
NASA's "Climate Spiral" depicting global temperature variations since 1880-2024
Depressing data but pretty "cool" way of depicting how we're doomed.
Depressing data but pretty "cool" way of depicting how we're doomed.
January 16, 2025 at 6:51 PM
NASA's "Climate Spiral" depicting global temperature variations since 1880-2024
Depressing data but pretty "cool" way of depicting how we're doomed.
Depressing data but pretty "cool" way of depicting how we're doomed.
Reposted by Faheem Farooq
Current students at IISER Mohali interviewed our alumnus @rhythmicspikes.bsky.social . Lovely interview and a good example of how serendipity can lead to discoveries and a fun career.
manthanmagazine.wordpress.com/2025/01/06/i...
manthanmagazine.wordpress.com/2025/01/06/i...
In Conversation with Dr. Abhilasha Joshi
As part of Manthan’s Alumni series, we bring to you an interview with Dr. Abhilasha Joshi who is currently an Assistant Professor (Reader F) at the National Center for Biological Sciences. Dr…
manthanmagazine.wordpress.com
January 7, 2025 at 7:07 AM
Current students at IISER Mohali interviewed our alumnus @rhythmicspikes.bsky.social . Lovely interview and a good example of how serendipity can lead to discoveries and a fun career.
manthanmagazine.wordpress.com/2025/01/06/i...
manthanmagazine.wordpress.com/2025/01/06/i...
Reposted by Faheem Farooq
We are diving into 2025 with how we finished 2024: with great research. The lab of Jan-Michael Peters discovered how #cohesin not only drives #chromatin architecture, but also links it to #epigenetics. Now in @embojournal.bsky.social:
www.embopress.org/doi/full/10....
www.imp.ac.at/news/article...
www.embopress.org/doi/full/10....
www.imp.ac.at/news/article...
January 3, 2025 at 7:50 AM
We are diving into 2025 with how we finished 2024: with great research. The lab of Jan-Michael Peters discovered how #cohesin not only drives #chromatin architecture, but also links it to #epigenetics. Now in @embojournal.bsky.social:
www.embopress.org/doi/full/10....
www.imp.ac.at/news/article...
www.embopress.org/doi/full/10....
www.imp.ac.at/news/article...
Reposted by Faheem Farooq
I guess I told you about the fact that SMC proteins like cohesin and condensin are a novel class of molecular motors that make loops into DNA (something we visualized first in 2018). These DNA loops are the fundamental motif that organize our chromosomes.
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December 13, 2024 at 7:12 PM
I guess I told you about the fact that SMC proteins like cohesin and condensin are a novel class of molecular motors that make loops into DNA (something we visualized first in 2018). These DNA loops are the fundamental motif that organize our chromosomes.
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Reposted by Faheem Farooq
I really love this comparison. I nicely shows how important calibration is for interrogating RNA-seq experiments.
We have had multiple discussions about why people have not previously observed the very dramatic reduction in transcription upon PNUTS depletion. So I looked at our own TT-seq data and analysed it without including the spike-in. The numbers speak for themselves! Spike-in calibration is important!
December 12, 2024 at 11:47 AM
I really love this comparison. I nicely shows how important calibration is for interrogating RNA-seq experiments.
Reposted by Faheem Farooq
Looking for a PhD position? Interested in understanding gene regulation using live-cell single-molecule imaging technologies? Apply for the NKI PhD program to join our lab or other NKI labs. bit.ly/3O4bOjq
December 2, 2024 at 4:03 PM
Looking for a PhD position? Interested in understanding gene regulation using live-cell single-molecule imaging technologies? Apply for the NKI PhD program to join our lab or other NKI labs. bit.ly/3O4bOjq
Reposted by Faheem Farooq
Re-reading your rejected manuscript
November 30, 2024 at 2:26 PM
Re-reading your rejected manuscript
Reposted by Faheem Farooq
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Evolution and function of chromatin domains across the tree of life - Nature Structural & Molecular Biology
Szalay et al. discuss cross-kingdom similarities and differences in 3D chromatin folding in relation to gene regulation, including in bacteria, archaea, mammals and plants. This comparison reveals cer...
www.nature.com
November 28, 2024 at 12:48 PM
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Ever wonder how #TADs compare across the tree of life?Look no further & read our Review!!!
Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals!
SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
Reposted by Faheem Farooq
A person on a bicycle is by far the most energy-efficient among animals and machines per distance traveled relative to body weight. The bicycle is magic.
www.jstor.org/stable/24923...
www.jstor.org/stable/24923...
November 24, 2024 at 11:12 PM
A person on a bicycle is by far the most energy-efficient among animals and machines per distance traveled relative to body weight. The bicycle is magic.
www.jstor.org/stable/24923...
www.jstor.org/stable/24923...
