Maz
@taghioskoui.bsky.social
Exploring Mass Spectrometry & the Origins of Life: Is Life a Common Cosmic Phenomenon?
Reposted by Maz
This is part of the reason that I’m working on a fully open-source MS instrument. It’s targeted for atmospheric monitoring rather than proteomics, but it’s a step toward making MS hardware much more accessible. Hoping to have it ready to unveil at ASMS 2026.
November 3, 2025 at 9:49 PM
This is part of the reason that I’m working on a fully open-source MS instrument. It’s targeted for atmospheric monitoring rather than proteomics, but it’s a step toward making MS hardware much more accessible. Hoping to have it ready to unveil at ASMS 2026.
Reposted by Maz
Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.
a spongebob squarepants scene with a mailbox and a flower
ALT: a spongebob squarepants scene with a mailbox and a flower
media.tenor.com
October 28, 2025 at 4:39 PM
Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.
Reposted by Maz
The history of science is filled with examples of serious consequences for those who chose to compromise integrity. Your peers are always watching, scrutinizing your methods, your data, and your conclusions. That level of accountability is part of what keeps the system honest.
August 2, 2025 at 5:04 AM
The history of science is filled with examples of serious consequences for those who chose to compromise integrity. Your peers are always watching, scrutinizing your methods, your data, and your conclusions. That level of accountability is part of what keeps the system honest.
Congrats to those on this list, and it's great to see that, instead of the usual nominations process, original ideas and compelling arguments evaluated blindly by an expert panel were selected, resulting in new faces on the list rather than the usual ones.
The Analytical Scientist | 2025
theanalyticalscientist.com
August 5, 2025 at 2:43 PM
Congrats to those on this list, and it's great to see that, instead of the usual nominations process, original ideas and compelling arguments evaluated blindly by an expert panel were selected, resulting in new faces on the list rather than the usual ones.
🎓 ✈️ Student Travel Award – Deadline Extended!
Grad students working in Harsh Environment Mass Spectrometry (HEMS): apply now for a $1500 travel award to attend the 2025 HEMS Workshop!
New deadline: August 8, 2025
Open to M.S., M.A., and Ph.D. students.
Grad students working in Harsh Environment Mass Spectrometry (HEMS): apply now for a $1500 travel award to attend the 2025 HEMS Workshop!
New deadline: August 8, 2025
Open to M.S., M.A., and Ph.D. students.
Student Travel Award Harsh Environment Mass Spectrometry Workshop
The HEMS-workshop focuses on the development of mass spectrometers for field
applications. Presentations are ranging from remotely controlled mass spectrometers deployed on t...
www.hems-workshop.org
August 4, 2025 at 6:46 PM
🎓 ✈️ Student Travel Award – Deadline Extended!
Grad students working in Harsh Environment Mass Spectrometry (HEMS): apply now for a $1500 travel award to attend the 2025 HEMS Workshop!
New deadline: August 8, 2025
Open to M.S., M.A., and Ph.D. students.
Grad students working in Harsh Environment Mass Spectrometry (HEMS): apply now for a $1500 travel award to attend the 2025 HEMS Workshop!
New deadline: August 8, 2025
Open to M.S., M.A., and Ph.D. students.
Deep Blood Proteomics Identifies over 12,000 Proteins Providing Valuable Information about the State of the Human Body. www.biorxiv.org/content/10.1...
August 4, 2025 at 12:11 AM
Deep Blood Proteomics Identifies over 12,000 Proteins Providing Valuable Information about the State of the Human Body. www.biorxiv.org/content/10.1...
Reposted by Maz
“…creates pressure on researchers to produce impressive results”
I think this is key. Is there not pressure to produce impressive results for private funding too?
With decreasing NIH funding, one could argue that scientists are at their most vulnerable, and that might compromise their integrity.
I think this is key. Is there not pressure to produce impressive results for private funding too?
With decreasing NIH funding, one could argue that scientists are at their most vulnerable, and that might compromise their integrity.
July 29, 2025 at 8:03 PM
“…creates pressure on researchers to produce impressive results”
I think this is key. Is there not pressure to produce impressive results for private funding too?
With decreasing NIH funding, one could argue that scientists are at their most vulnerable, and that might compromise their integrity.
I think this is key. Is there not pressure to produce impressive results for private funding too?
With decreasing NIH funding, one could argue that scientists are at their most vulnerable, and that might compromise their integrity.
COI issues keep surfacing with every sponsored paper published. Hard to tell when this will stop or if truly independent, unsponsored research is going to disappear altogether.
There have been suggestions that conflicts of interest should be clearly displayed by speakers at all times.
I've got a leak from a factory that is preparing for #ASMS2026 and they've shared their new conflict of interest outfits for the presenters. (I think @benneely.com had this idea?)
Thoughts?
I've got a leak from a factory that is preparing for #ASMS2026 and they've shared their new conflict of interest outfits for the presenters. (I think @benneely.com had this idea?)
Thoughts?
July 30, 2025 at 2:52 AM
COI issues keep surfacing with every sponsored paper published. Hard to tell when this will stop or if truly independent, unsponsored research is going to disappear altogether.
Reposted by Maz
Backyard Proteomics: A Case Study with the Black Widow Spider #JProteomeRes #MassSpec pubs.acs.org/doi/10.1021/...
pubs.acs.org
July 29, 2025 at 11:04 AM
Backyard Proteomics: A Case Study with the Black Widow Spider #JProteomeRes #MassSpec pubs.acs.org/doi/10.1021/...
“Legacy tools like mass spectrometry shred proteins into fragments and miss critical protein modification patterns that change protein function, which costs industries billions in failed drug trials and misdiagnoses.”
www.globenewswire.com/news-release...
www.globenewswire.com/news-release...
Portal Biotech Raises $35 Million Series A, Leveraging AI to Deliver the World’s First Full-Length Single-Molecule Protein Sequencer
Portal Biotech Raises $35 Million Series A, Leveraging AI to Deliver the World’s First Full-Length Single-Molecule Protein Sequencer...
www.globenewswire.com
July 29, 2025 at 7:25 PM
“Legacy tools like mass spectrometry shred proteins into fragments and miss critical protein modification patterns that change protein function, which costs industries billions in failed drug trials and misdiagnoses.”
www.globenewswire.com/news-release...
www.globenewswire.com/news-release...
🚨 Call for Abstracts: #HEMS2025
🌍 Harsh-Environment Mass Spectrometry Workshop
🗓️ Sept 15–18, 2025 | Virginia Beach, VA
🔬 Focus: Rugged, field MS in extreme conditions and instrumentation in general
📅 Abstract deadline: Aug 15
🔗 www.hems-workshop.org
🌍 Harsh-Environment Mass Spectrometry Workshop
🗓️ Sept 15–18, 2025 | Virginia Beach, VA
🔬 Focus: Rugged, field MS in extreme conditions and instrumentation in general
📅 Abstract deadline: Aug 15
🔗 www.hems-workshop.org
Harsh Environment Mass Spectrometry Workshop
The HEMS-workshop focuses on the development of mass spectrometers for field
applications. Presentations are ranging from remotely controlled mass spectrometers deployed on t...
www.hems-workshop.org
July 22, 2025 at 3:56 PM
🚨 Call for Abstracts: #HEMS2025
🌍 Harsh-Environment Mass Spectrometry Workshop
🗓️ Sept 15–18, 2025 | Virginia Beach, VA
🔬 Focus: Rugged, field MS in extreme conditions and instrumentation in general
📅 Abstract deadline: Aug 15
🔗 www.hems-workshop.org
🌍 Harsh-Environment Mass Spectrometry Workshop
🗓️ Sept 15–18, 2025 | Virginia Beach, VA
🔬 Focus: Rugged, field MS in extreme conditions and instrumentation in general
📅 Abstract deadline: Aug 15
🔗 www.hems-workshop.org
Reposted by Maz
MY UNIVERSITY WILL DO PROTEOMICS (by LCMS) on 1 MILLION PEOPLE - LONGITUDINALLY?? proteomicsnews.blogspot.com/2025/04/pitt...
Pitt announces plans to do Proteomics /multi-omics of 1 MILLION PEOPLE!
My new home is planning to do deep mult-omics - proteomics by MASS SPECTROMETRY - of ONE MILLION PEOPLE! The 12 hour launch event appears...
proteomicsnews.blogspot.com
April 27, 2025 at 4:00 PM
MY UNIVERSITY WILL DO PROTEOMICS (by LCMS) on 1 MILLION PEOPLE - LONGITUDINALLY?? proteomicsnews.blogspot.com/2025/04/pitt...
Reposted by Maz
I bet you guys have already discussed this one but it was new to me this morning and very very strange. proteomicsnews.blogspot.com/2025/04/prep...
Preprint compares 7 plasma proteomics methods - and doesn't get a single good correlation!
Title is overstated, I guess, there are some "strong correlations" but not the ones I really care about. SomaScan 11k vs 7k get a strong. Sa...
proteomicsnews.blogspot.com
April 10, 2025 at 12:34 PM
I bet you guys have already discussed this one but it was new to me this morning and very very strange. proteomicsnews.blogspot.com/2025/04/prep...
Reposted by Maz
News in Proteomics Research blog post | Preprint compares 7 plasma proteomics methods - and doesn't get a single good correlation! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
April 10, 2025 at 12:40 PM
News in Proteomics Research blog post | Preprint compares 7 plasma proteomics methods - and doesn't get a single good correlation! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
Not even a single scientist in the team to catch this. Horrible.
Trump claimed the Biden administration spent $8 million "making mice transgender." The White House tried to back up this number with records of funding for research into cancer, asthma, and HIV, some of which used *transgenic* (genetically modified) mice.
Trump Decried Millions Spent 'Making Mice Transgender.' It Was Cancer and Asthma Research
President Trump falsely claimed that Biden spent $8 million on 'making mice transgender,' but the real research was for human health.
www.rollingstone.com
March 6, 2025 at 12:31 AM
Not even a single scientist in the team to catch this. Horrible.
www.medrxiv.org/content/10.1...
“SomaScan 11K offers the most comprehensive coverage of the plasma proteome, making it the best platform available for discovery studies with the objective of identifying previously unknown biological roles for the largest set of proteins.”
“SomaScan 11K offers the most comprehensive coverage of the plasma proteome, making it the best platform available for discovery studies with the objective of identifying previously unknown biological roles for the largest set of proteins.”
Plasma proteomic comparisons change as coverage expands for SomaLogic and Olink
The number of assays on highly-multiplexed proteomic platforms has grown ten-fold over the past 15 years from less than 1,000 to >11,000. The leading aptamer-based and antibody-based platforms have di...
www.medrxiv.org
February 24, 2025 at 11:35 PM
www.medrxiv.org/content/10.1...
“SomaScan 11K offers the most comprehensive coverage of the plasma proteome, making it the best platform available for discovery studies with the objective of identifying previously unknown biological roles for the largest set of proteins.”
“SomaScan 11K offers the most comprehensive coverage of the plasma proteome, making it the best platform available for discovery studies with the objective of identifying previously unknown biological roles for the largest set of proteins.”
15% max indirect rate for NIH proposals.
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 5:30 AM
15% max indirect rate for NIH proposals.
Reposted by Maz
The OSIRIS-REx spacecraft collected rock and dust samples from an asteroid in October 2020, delivering them to Earth three years later.
In today's episode, how an asteroid sample is prompting astrobiologists to rethink a few things.
Listen here 🎧:
https://buff.ly/3Mut28J
In today's episode, how an asteroid sample is prompting astrobiologists to rethink a few things.
Listen here 🎧:
https://buff.ly/3Mut28J
February 4, 2025 at 9:47 PM
The OSIRIS-REx spacecraft collected rock and dust samples from an asteroid in October 2020, delivering them to Earth three years later.
In today's episode, how an asteroid sample is prompting astrobiologists to rethink a few things.
Listen here 🎧:
https://buff.ly/3Mut28J
In today's episode, how an asteroid sample is prompting astrobiologists to rethink a few things.
Listen here 🎧:
https://buff.ly/3Mut28J
Reposted by Maz
After a VERY long time, it got published: rdcu.be/d8KyK.
My deep thanks to Sonja, Matthias and the other authors for analysing my own cancer. Now to convince my clinicians to use it for treating me. The battle is far from over.
My deep thanks to Sonja, Matthias and the other authors for analysing my own cancer. Now to convince my clinicians to use it for treating me. The battle is far from over.
Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma
npj Precision Oncology - Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma
rdcu.be
February 5, 2025 at 8:25 PM
After a VERY long time, it got published: rdcu.be/d8KyK.
My deep thanks to Sonja, Matthias and the other authors for analysing my own cancer. Now to convince my clinicians to use it for treating me. The battle is far from over.
My deep thanks to Sonja, Matthias and the other authors for analysing my own cancer. Now to convince my clinicians to use it for treating me. The battle is far from over.
“They came for the socialists, and I did not speak out—I was not a socialist. They came for the trade unionists, and I did not speak out—I was not a trade unionist. They came for the Jews, and I did not speak out— I was not a Jew. Then they came for me—and there was no one left to speak for me.”
Dear Science friends:
A coordinated effort across science & academia is appropriate in response to the fascist moves against science funding and DEIJ by the current administration.
It should be effective and broadly supported.
What are your ideas for action?
A coordinated effort across science & academia is appropriate in response to the fascist moves against science funding and DEIJ by the current administration.
It should be effective and broadly supported.
What are your ideas for action?
February 2, 2025 at 5:30 PM
“They came for the socialists, and I did not speak out—I was not a socialist. They came for the trade unionists, and I did not speak out—I was not a trade unionist. They came for the Jews, and I did not speak out— I was not a Jew. Then they came for me—and there was no one left to speak for me.”
USAID website is shutdown. It has nearly 20,000 employees.
www.usaid.gov/about-us
www.usaid.gov/about-us
www.usaid.gov
February 2, 2025 at 3:48 AM
USAID website is shutdown. It has nearly 20,000 employees.
www.usaid.gov/about-us
www.usaid.gov/about-us
When climate change awareness helped Tesla, he was a vocal advocate. When OpenAI was ahead, he wanted AI safety regulations. He no longer talks about those. It’s a pattern—align with a cause when it’s useful, abandon it when it’s not. Now, the cause is deficit, but the true intention is unknown.
NEW: Sources tell my office that Treasury Secretary Bessent has granted DOGE *full* access to this system. Social Security and Medicare benefits, grants, payments to government contractors, including those that compete directly with Musk's own companies. All of it.
NEWS: Wyden Demands Answers Following Report of Musk Personnel Seeking Access to Highly Sensitive U.S. Treasury Payments System
February 1, 2025 at 10:58 PM
When climate change awareness helped Tesla, he was a vocal advocate. When OpenAI was ahead, he wanted AI safety regulations. He no longer talks about those. It’s a pattern—align with a cause when it’s useful, abandon it when it’s not. Now, the cause is deficit, but the true intention is unknown.
Reposted by Maz
Researchers found 14 of the 20 amino acids essential for life on Earth in samples from the ancient asteroid Bennu.
Dr. Danny Glavin and Dr. Dante Lauretta join us to discuss the samples and what they mean for the search for life beyond Earth.
Dr. Danny Glavin and Dr. Dante Lauretta join us to discuss the samples and what they mean for the search for life beyond Earth.
Building Blocks Of Life Found On Asteroid Bennu
Early analysis of asteroid samples from NASA’s OSIRIS-REx mission show the residue of an icy brine, and a soup of amino acids.
buff.ly
January 31, 2025 at 7:41 PM
Researchers found 14 of the 20 amino acids essential for life on Earth in samples from the ancient asteroid Bennu.
Dr. Danny Glavin and Dr. Dante Lauretta join us to discuss the samples and what they mean for the search for life beyond Earth.
Dr. Danny Glavin and Dr. Dante Lauretta join us to discuss the samples and what they mean for the search for life beyond Earth.
Elon Musk slashed 6,000 jobs at Twitter and thinks a similar approach could “reshape” the federal government, which has 2.25 million employees (375X). But scaling laws don’t work like that. He knows(?) Falcon 9 → Starship or toy car → Tesla weren’t just “make it bigger.”
January 29, 2025 at 4:14 AM
Elon Musk slashed 6,000 jobs at Twitter and thinks a similar approach could “reshape” the federal government, which has 2.25 million employees (375X). But scaling laws don’t work like that. He knows(?) Falcon 9 → Starship or toy car → Tesla weren’t just “make it bigger.”
Reposted by Maz
Sen Tim Kaine (D-VA) speech about Trump Admin. "buyout" idea for federal workers
"He's tricked hundreds of people with that offer. If you accept that offer and resign, he'll stiff you just like he stiffed the contractors. He doesn't have any authority to do this. Do not be fooled by this guy"
"He's tricked hundreds of people with that offer. If you accept that offer and resign, he'll stiff you just like he stiffed the contractors. He doesn't have any authority to do this. Do not be fooled by this guy"
January 29, 2025 at 12:47 AM
Sen Tim Kaine (D-VA) speech about Trump Admin. "buyout" idea for federal workers
"He's tricked hundreds of people with that offer. If you accept that offer and resign, he'll stiff you just like he stiffed the contractors. He doesn't have any authority to do this. Do not be fooled by this guy"
"He's tricked hundreds of people with that offer. If you accept that offer and resign, he'll stiff you just like he stiffed the contractors. He doesn't have any authority to do this. Do not be fooled by this guy"