Matt Padula
@mattpadula.bsky.social
Semi-accurate impersonation of an Associate Professor at Uni of Technology Sydney. Does proteomics, fixes mass specs, does 2D-PAGE. Rides mountain bikes when he should be working. Brutal Metal listener. Dealing with ongoing cancer. EiC of Proteomes.
Reposted by Matt Padula
Reposted by Matt Padula
A lovely tribute to Amos Bairoch from Vivienne Baillie Gerritsen, author of the always interesting Protein Spotlight blog for #SwissProt
www.proteinspotlight.org/back_issues/...
www.proteinspotlight.org/back_issues/...
a tribute
As I crossed Geneva this morning and approached the office, I felt a growing sadness. I realised that, if I was walking in this direction in the first place, it was thanks to Amos Bairoch. Flashback t...
www.proteinspotlight.org
December 18, 2025 at 3:57 PM
A lovely tribute to Amos Bairoch from Vivienne Baillie Gerritsen, author of the always interesting Protein Spotlight blog for #SwissProt
www.proteinspotlight.org/back_issues/...
www.proteinspotlight.org/back_issues/...
Assistance please. Jens and I updated the Top Down Proteomics entry in Wikipedia because it was out of date and incomplete. en.wikipedia.org/wiki/Top-dow...
Top-down proteomics - Wikipedia
en.wikipedia.org
December 12, 2025 at 6:17 AM
Assistance please. Jens and I updated the Top Down Proteomics entry in Wikipedia because it was out of date and incomplete. en.wikipedia.org/wiki/Top-dow...
Having avoided glycopeptides for years, I now need to analyse them. Can someone point me in the direction of useful publications that describe the practicalities of doing this properly to maximise data quality? Source conditions, fragmentation settings etc. Thanks.
December 8, 2025 at 5:46 AM
Having avoided glycopeptides for years, I now need to analyse them. Can someone point me in the direction of useful publications that describe the practicalities of doing this properly to maximise data quality? Source conditions, fragmentation settings etc. Thanks.
We were dumb enough to let this happen....
December 5, 2025 at 11:29 PM
We were dumb enough to let this happen....
Reposted by Matt Padula
ProteoformDB: A Built-In Application to Generate Proteoform Database pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
December 4, 2025 at 3:40 PM
ProteoformDB: A Built-In Application to Generate Proteoform Database pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted by Matt Padula
The unalterable fact that all skills are perishable is something you only learn through experience.
December 4, 2025 at 8:30 PM
The unalterable fact that all skills are perishable is something you only learn through experience.
Reposted by Matt Padula
I’m turning down journal reviews if the journal doesn’t update activities to ORCID. I get a lot of requests and I need to prioritize somehow. I ain’t collecting “reviewer certifications” from Genome biology and scientific reports, etc., when Nature Family and ACS give me credit for my time.
November 29, 2025 at 1:50 PM
I’m turning down journal reviews if the journal doesn’t update activities to ORCID. I get a lot of requests and I need to prioritize somehow. I ain’t collecting “reviewer certifications” from Genome biology and scientific reports, etc., when Nature Family and ACS give me credit for my time.
Am I the only (grumpy) person annoyed when an email starts with "I hope this email finds you well"?
So tempted to reply with "Actually it doesn't find me well. Still have cancer."
Just get to the point of why you are contacting me please.
So tempted to reply with "Actually it doesn't find me well. Still have cancer."
Just get to the point of why you are contacting me please.
November 15, 2025 at 3:45 AM
Am I the only (grumpy) person annoyed when an email starts with "I hope this email finds you well"?
So tempted to reply with "Actually it doesn't find me well. Still have cancer."
Just get to the point of why you are contacting me please.
So tempted to reply with "Actually it doesn't find me well. Still have cancer."
Just get to the point of why you are contacting me please.
Reposted by Matt Padula
Proteoform Mapping Calls for a Combined Effort From Bottom‐Up and Top‐Down Proteomics analyticalsciencejou...
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#proteomics #prot-paper
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#proteomics #prot-paper
November 13, 2025 at 10:00 AM
Proteoform Mapping Calls for a Combined Effort From Bottom‐Up and Top‐Down Proteomics analyticalsciencejou...
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#proteomics #prot-paper
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#proteomics #prot-paper
Reposted by Matt Padula
"Biomarker studies are the greatest reproducibility crisis in science" (M. Uhlén, 2025).
November 11, 2025 at 6:02 PM
"Biomarker studies are the greatest reproducibility crisis in science" (M. Uhlén, 2025).
Reposted by Matt Padula
Thinking about putting this sign outside my facilities door . 🤔
November 5, 2025 at 2:13 AM
Thinking about putting this sign outside my facilities door . 🤔
Reposted by Matt Padula
To be honest, when I see conferences announced that have a majority of male invited speakers, I think the organisers are not trying hard enough. We have so many excellent #FemalesinMS and resources available there is really no excuse for it anymore #massspec #teammassspec #lipidomics #metabolomics
October 27, 2025 at 10:45 PM
To be honest, when I see conferences announced that have a majority of male invited speakers, I think the organisers are not trying hard enough. We have so many excellent #FemalesinMS and resources available there is really no excuse for it anymore #massspec #teammassspec #lipidomics #metabolomics
Reposted by Matt Padula
🎤 Get ready for more ANZMetSoc ECR Rapid-Fire!
Hear 3min talks from 2 of 10 #ECR speakers:
Emily Sunnucks (UT Sydney) on multi-omics & death 🧩Chrystal O’Connor (Lincoln Uni, NZ) on Indigenous-guided metabolomics 🌿
📅 Oct 29
🏆 Vote People’s Choice: tinyurl.com/ECR-Rapid-Fire
#ANZMetSoc #Metabolomics
Hear 3min talks from 2 of 10 #ECR speakers:
Emily Sunnucks (UT Sydney) on multi-omics & death 🧩Chrystal O’Connor (Lincoln Uni, NZ) on Indigenous-guided metabolomics 🌿
📅 Oct 29
🏆 Vote People’s Choice: tinyurl.com/ECR-Rapid-Fire
#ANZMetSoc #Metabolomics
October 21, 2025 at 5:51 AM
🎤 Get ready for more ANZMetSoc ECR Rapid-Fire!
Hear 3min talks from 2 of 10 #ECR speakers:
Emily Sunnucks (UT Sydney) on multi-omics & death 🧩Chrystal O’Connor (Lincoln Uni, NZ) on Indigenous-guided metabolomics 🌿
📅 Oct 29
🏆 Vote People’s Choice: tinyurl.com/ECR-Rapid-Fire
#ANZMetSoc #Metabolomics
Hear 3min talks from 2 of 10 #ECR speakers:
Emily Sunnucks (UT Sydney) on multi-omics & death 🧩Chrystal O’Connor (Lincoln Uni, NZ) on Indigenous-guided metabolomics 🌿
📅 Oct 29
🏆 Vote People’s Choice: tinyurl.com/ECR-Rapid-Fire
#ANZMetSoc #Metabolomics
Reposted by Matt Padula
Correlation isn’t causation, as the mantra goes—but statistical noise in correlational data can reveal causal information. When X and Y are causally linked, their noise tends to be asymmetric & this can guide #CausalInference. Check out our 📃👇 doi.org/10.1111/nous... #philsky #philsci #StatsSky #HPS
October 21, 2025 at 9:20 AM
Correlation isn’t causation, as the mantra goes—but statistical noise in correlational data can reveal causal information. When X and Y are causally linked, their noise tends to be asymmetric & this can guide #CausalInference. Check out our 📃👇 doi.org/10.1111/nous... #philsky #philsci #StatsSky #HPS
Reposted by Matt Padula
AlphaDIA enables DIA transfer learning for feature-free proteomics - @mannlab.bsky.social @jalew188.bsky.social go.nature.com/4qmEQMM
AlphaDIA enables DIA transfer learning for feature-free proteomics - Nature Biotechnology
An open-source platform for data-independent acquisition proteomics adapts predicted libraries to experimental settings.
go.nature.com
October 21, 2025 at 4:53 PM
AlphaDIA enables DIA transfer learning for feature-free proteomics - @mannlab.bsky.social @jalew188.bsky.social go.nature.com/4qmEQMM
I'll just leave this here: jocnf.pubpub.org/pub/qag76ip8...
Principles for proper peer review
jocnf.pubpub.org
October 8, 2025 at 5:19 AM
I'll just leave this here: jocnf.pubpub.org/pub/qag76ip8...
Reposted by Matt Padula
Read more in @natcomms.nature.com by:
@clairerich.bsky.social
@lanamcclements.bsky.social
@mattpadula.bsky.social
@louisecole.bsky.social
🏫
@utsengage.bsky.social
@centenaryinstitute.bsky.social
@hmriaustralia.bsky.social
@garvaninstitute.bsky.social
www.nature.com/articles/s41...
@clairerich.bsky.social
@lanamcclements.bsky.social
@mattpadula.bsky.social
@louisecole.bsky.social
🏫
@utsengage.bsky.social
@centenaryinstitute.bsky.social
@hmriaustralia.bsky.social
@garvaninstitute.bsky.social
www.nature.com/articles/s41...
Matrix directs trophoblast differentiation in a bioprinted organoid model of early placental development - Nature Communications
The placenta plays vital roles in supporting fetal development. Here, Richards et al. develop a high-throughput bioprinted trophoblast organoid model to recapitulate the microenvironment of the e...
www.nature.com
September 22, 2025 at 12:59 PM
Medical update: last infusion of six cycles of chemo. It's done. Oncologist is predicting more sometime, but cancer gone AFAIAC. PET scan in November.
Feel tired but that's likely poor sleep. Have to ignore it cause I'm racing the MTB on Sunday....
Feel tired but that's likely poor sleep. Have to ignore it cause I'm racing the MTB on Sunday....
September 19, 2025 at 11:34 PM
Medical update: last infusion of six cycles of chemo. It's done. Oncologist is predicting more sometime, but cancer gone AFAIAC. PET scan in November.
Feel tired but that's likely poor sleep. Have to ignore it cause I'm racing the MTB on Sunday....
Feel tired but that's likely poor sleep. Have to ignore it cause I'm racing the MTB on Sunday....
Reposted by Matt Padula
Proteomics Webinar: DIA with FragPipe, DIA-NN, and Skyline
Presenters: Eduard Sabidó and Brendan MacLean
When: Tuesday, September 16, 8am (Pacific Time)
Register Now ... skyline.ms/project/home...
#massspec #proteomics
Presenters: Eduard Sabidó and Brendan MacLean
When: Tuesday, September 16, 8am (Pacific Time)
Register Now ... skyline.ms/project/home...
#massspec #proteomics
Start Page: /home/software/Skyline/events/2025 Webinars/Webinar 26
skyline.ms
September 15, 2025 at 8:26 AM
Proteomics Webinar: DIA with FragPipe, DIA-NN, and Skyline
Presenters: Eduard Sabidó and Brendan MacLean
When: Tuesday, September 16, 8am (Pacific Time)
Register Now ... skyline.ms/project/home...
#massspec #proteomics
Presenters: Eduard Sabidó and Brendan MacLean
When: Tuesday, September 16, 8am (Pacific Time)
Register Now ... skyline.ms/project/home...
#massspec #proteomics
This is really interesting and worth five minutes of your time to read.
www.smh.com.au/world/north-...
www.smh.com.au/world/north-...
The dangerous logic behind the killing of Charlie Kirk
Political extremism isn’t caused by other people saying things you don’t like. It’s caused by those people having no constructive way to air their frustrations.
www.smh.com.au
September 15, 2025 at 8:08 AM
This is really interesting and worth five minutes of your time to read.
www.smh.com.au/world/north-...
www.smh.com.au/world/north-...
Reposted by Matt Padula
Pre-analytical drivers of bias in bead-enriched plasma proteomics | EMBO Molecular Medicine www.embopress.org/do...
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#proteomics #prot-paper
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#proteomics #prot-paper
September 13, 2025 at 8:40 AM
Pre-analytical drivers of bias in bead-enriched plasma proteomics | EMBO Molecular Medicine www.embopress.org/do...
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#proteomics #prot-paper
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#proteomics #prot-paper
