Sheila I. Jensen
@sheilaijensen.bsky.social
Group leader for the Sustainable Microbial Applications group at DTU Biosustain. Sustainability, Synthetic biology, Biotechnology, Metabolic engineering, bacteria, Synbio
Pinned
Dear Synbio community.
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
Dear international colleagues in Denmark.
Remember that many of you can also vote in the upcoming election the 18th of November.
I don't care what you vote, but please consider voting 💚
Remember that many of you can also vote in the upcoming election the 18th of November.
I don't care what you vote, but please consider voting 💚
October 25, 2025 at 3:04 PM
Dear international colleagues in Denmark.
Remember that many of you can also vote in the upcoming election the 18th of November.
I don't care what you vote, but please consider voting 💚
Remember that many of you can also vote in the upcoming election the 18th of November.
I don't care what you vote, but please consider voting 💚
Reposted by Sheila I. Jensen
1/3 To those interested in microbial iron & metal transport: In 1992, the late JB Neilands (UCB), the pioneer in the study of Fe transport entrusted me with his collection of purified siderophores from a wide range of microbes—many of them unique chemical species that can no longer be reproduced
October 14, 2025 at 2:54 PM
1/3 To those interested in microbial iron & metal transport: In 1992, the late JB Neilands (UCB), the pioneer in the study of Fe transport entrusted me with his collection of purified siderophores from a wide range of microbes—many of them unique chemical species that can no longer be reproduced
Reposted by Sheila I. Jensen
Bacteria in hot springs can move against fast water flow without flagella. Instead, they use pili like grappling hooks to crawl upstream, revealing a surprising survival strategy in extreme environments.
isme-microbes.org/hot-spring-b...
#microbes #bacterialmotility #extremophiles #hotsprings
isme-microbes.org/hot-spring-b...
#microbes #bacterialmotility #extremophiles #hotsprings
October 13, 2025 at 4:56 PM
Bacteria in hot springs can move against fast water flow without flagella. Instead, they use pili like grappling hooks to crawl upstream, revealing a surprising survival strategy in extreme environments.
isme-microbes.org/hot-spring-b...
#microbes #bacterialmotility #extremophiles #hotsprings
isme-microbes.org/hot-spring-b...
#microbes #bacterialmotility #extremophiles #hotsprings
Reposted by Sheila I. Jensen
Jane Goodall, known for her pioneering work with chimpanzees, has passed away aged 91
go.nature.com/46QHIZk
go.nature.com/46QHIZk
Jane Goodall’s legacy: three ways she changed science
Nature - The primatologist challenged what it meant to be a scientist.
go.nature.com
October 4, 2025 at 1:19 PM
Jane Goodall, known for her pioneering work with chimpanzees, has passed away aged 91
go.nature.com/46QHIZk
go.nature.com/46QHIZk
Reposted by Sheila I. Jensen
Jane Goodall, pioneering chimpanzee zoologist who revealed the animals’ links to humans, dies aged 91
www.independent.co.uk/news/uk/home...
www.independent.co.uk/news/uk/home...
Jane Goodall, much-loved pioneering chimpanzee expert, dies aged 91
Award-winning primatologist who established world’s longest-running chimp study still lectured on conservation and climate even over age of 91
www.independent.co.uk
October 1, 2025 at 6:31 PM
Jane Goodall, pioneering chimpanzee zoologist who revealed the animals’ links to humans, dies aged 91
www.independent.co.uk/news/uk/home...
www.independent.co.uk/news/uk/home...
En "lille" overset detalje
Ved ikke om jeg nogensinde vil kunne få et normaliseret forhold til de fleste Israelere igen (medmindre de går igennem deradikalisering), men det bliver da kun sværere, hvis ingen af dem der bla. har været med til at sulte folk ihjel bliver dømt for deres forbrydelser 💔🕊️
Ved ikke om jeg nogensinde vil kunne få et normaliseret forhold til de fleste Israelere igen (medmindre de går igennem deradikalisering), men det bliver da kun sværere, hvis ingen af dem der bla. har været med til at sulte folk ihjel bliver dømt for deres forbrydelser 💔🕊️
September 30, 2025 at 12:48 PM
En "lille" overset detalje
Ved ikke om jeg nogensinde vil kunne få et normaliseret forhold til de fleste Israelere igen (medmindre de går igennem deradikalisering), men det bliver da kun sværere, hvis ingen af dem der bla. har været med til at sulte folk ihjel bliver dømt for deres forbrydelser 💔🕊️
Ved ikke om jeg nogensinde vil kunne få et normaliseret forhold til de fleste Israelere igen (medmindre de går igennem deradikalisering), men det bliver da kun sværere, hvis ingen af dem der bla. har været med til at sulte folk ihjel bliver dømt for deres forbrydelser 💔🕊️
Reposted by Sheila I. Jensen
Really excited to share my first paper from the Whitney lab, alongside an amazing grad student, Polina. Here we identify a chaperone family required for the folding of a central domain of T7SS toxins, and solve the structure of the chaperone-toxin complex. www.pnas.org/doi/10.1073/...
A widespread family of molecular chaperones promotes the intracellular stability of type VIIb secretion system–exported toxins | PNAS
To survive in highly competitive environments, bacteria use specialized secretion
systems to deliver antibacterial toxins into neighboring cells, t...
www.pnas.org
September 15, 2025 at 11:41 PM
Really excited to share my first paper from the Whitney lab, alongside an amazing grad student, Polina. Here we identify a chaperone family required for the folding of a central domain of T7SS toxins, and solve the structure of the chaperone-toxin complex. www.pnas.org/doi/10.1073/...
Reposted by Sheila I. Jensen
Please repost!
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
efzu.fa.em2.oraclecloud.com
September 12, 2025 at 11:43 AM
Please repost!
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
Reposted by Sheila I. Jensen
New York Times article discusses @nature.com paper by our Rune Dietz, Christian Sonne, and others at @au.dk and the University of Copenhagen 🌐🐋🧪🌏
@newyorktimeshaiku.bsky.social @ucph.bsky.social
#Science #Research #impact #Mercury #Arcticchange
@newyorktimeshaiku.bsky.social @ucph.bsky.social
#Science #Research #impact #Mercury #Arcticchange
Study Shows Mercury Levels in Arctic Wildlife Could Rise for Centuries
www.nytimes.com
September 3, 2025 at 12:47 PM
New York Times article discusses @nature.com paper by our Rune Dietz, Christian Sonne, and others at @au.dk and the University of Copenhagen 🌐🐋🧪🌏
@newyorktimeshaiku.bsky.social @ucph.bsky.social
#Science #Research #impact #Mercury #Arcticchange
@newyorktimeshaiku.bsky.social @ucph.bsky.social
#Science #Research #impact #Mercury #Arcticchange
Reposted by Sheila I. Jensen
#Synthetic C1 #metabolism in #Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway—led by J. Turlin, M. G. Alván, @oscarpuiggene.bsky.social w/@stefanodonati.bsky.social & @sebwenk.bsky.social @mbio.bsky.social #SynBio
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Synthetic C1 metabolism in Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway | mBio
Soluble C1 feedstocks, such as formate and methanol, have gained attention as sustainable substrates for biotechnology, with the potential to reduce greenhouse gas emissions and reliance on sugar-based resources. Despite their promise, the metabolic ...
journals.asm.org
August 21, 2025 at 3:45 PM
#Synthetic C1 #metabolism in #Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway—led by J. Turlin, M. G. Alván, @oscarpuiggene.bsky.social w/@stefanodonati.bsky.social & @sebwenk.bsky.social @mbio.bsky.social #SynBio
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
1/3 Today is #worldorangutanday so here some pictures of these magnificent great apes from when we visited Borneo/Kalimantan in 2018. Orangutan means 'people of the forest' (orang=person; hutan=forest), and this critically endangered species is one of humans closest relatives.
August 19, 2025 at 6:22 AM
1/3 Today is #worldorangutanday so here some pictures of these magnificent great apes from when we visited Borneo/Kalimantan in 2018. Orangutan means 'people of the forest' (orang=person; hutan=forest), and this critically endangered species is one of humans closest relatives.
Reposted by Sheila I. Jensen
1/ 🚨 New preprint!
We've developed a robust IDMS-based LC-MS/MS workflow for high-throughput intracellular metabolomics in diverse bacteria. www.biorxiv.org/content/10.1...
#Metabolomics #MassSpec #SystemsBiology
We've developed a robust IDMS-based LC-MS/MS workflow for high-throughput intracellular metabolomics in diverse bacteria. www.biorxiv.org/content/10.1...
#Metabolomics #MassSpec #SystemsBiology
A Robust Isotope Ratio LC-MS/MS Workflow for High-Throughput Metabolic Profiling of Bacteria
Stable isotope dilution mass spectrometry (IDMS) has become a cornerstone of quantitative metabolomics, enabling accurate intracellular metabolite quantification across a range of biological systems. ...
www.biorxiv.org
August 12, 2025 at 9:50 AM
1/ 🚨 New preprint!
We've developed a robust IDMS-based LC-MS/MS workflow for high-throughput intracellular metabolomics in diverse bacteria. www.biorxiv.org/content/10.1...
#Metabolomics #MassSpec #SystemsBiology
We've developed a robust IDMS-based LC-MS/MS workflow for high-throughput intracellular metabolomics in diverse bacteria. www.biorxiv.org/content/10.1...
#Metabolomics #MassSpec #SystemsBiology
Reposted by Sheila I. Jensen
Harvard today, your institution tomorrow.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
May 22, 2025 at 6:38 PM
Harvard today, your institution tomorrow.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
Reposted by Sheila I. Jensen
Save the date - this is going to be a great conference!
Discover the #SyntheticBiology based innovations driving improvements in human health and planetary sustainability! #SynBio26
Join us at the intersection of bioengineering and medical science for sharing, networking and collaboration.
🗓️11-13 March 2026
📎Meeting info: bit.ly/43nlbBW
#ALife ⚙️🧫
Join us at the intersection of bioengineering and medical science for sharing, networking and collaboration.
🗓️11-13 March 2026
📎Meeting info: bit.ly/43nlbBW
#ALife ⚙️🧫
May 20, 2025 at 10:05 AM
Save the date - this is going to be a great conference!
Reposted by Sheila I. Jensen
New paper out!
We discovered a tiny archaeon with the smallest known archaeal genome — only 238 kbp!
Candidatus Sukunaarchaeum mirabile has almost no recognizable metabolic pathways and may rely heavily on a host to survive.
It also represents a novel, deep-branching lineage in the archaeal tree.
We discovered a tiny archaeon with the smallest known archaeal genome — only 238 kbp!
Candidatus Sukunaarchaeum mirabile has almost no recognizable metabolic pathways and may rely heavily on a host to survive.
It also represents a novel, deep-branching lineage in the archaeal tree.
A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome https://www.biorxiv.org/content/10.1101/2025.05.02.651781v1
May 3, 2025 at 5:08 AM
New paper out!
We discovered a tiny archaeon with the smallest known archaeal genome — only 238 kbp!
Candidatus Sukunaarchaeum mirabile has almost no recognizable metabolic pathways and may rely heavily on a host to survive.
It also represents a novel, deep-branching lineage in the archaeal tree.
We discovered a tiny archaeon with the smallest known archaeal genome — only 238 kbp!
Candidatus Sukunaarchaeum mirabile has almost no recognizable metabolic pathways and may rely heavily on a host to survive.
It also represents a novel, deep-branching lineage in the archaeal tree.
Reposted by Sheila I. Jensen
As the Trump administration destroys science in the United States, keep an eye on what is happening in Serbia.
Researchers say the rule will make it impossible for the majority of scientists in the country to carry on with, or to apply to, prestigious ERC research grants, or grants from Serbia’s own national science foundation.
Serbia limits academics’ research time to just one hour a day
Researchers say controversial policy will block majority of scientists from applying for grants
www.chemistryworld.com
April 27, 2025 at 5:59 PM
As the Trump administration destroys science in the United States, keep an eye on what is happening in Serbia.
Reposted by Sheila I. Jensen
I'm a bit miffed that I only got the email about this half an hour ago, but at long last, our antiSMASH 8 paper is out.
antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation academic.oup.com/nar/advance-... #jcampubs
antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation
Abstract. Microorganisms synthesize small bioactive compounds through their secondary or specialized metabolism. Those compounds play an important role in
academic.oup.com
April 25, 2025 at 5:41 PM
I'm a bit miffed that I only got the email about this half an hour ago, but at long last, our antiSMASH 8 paper is out.
Reposted by Sheila I. Jensen
Dear Synbio community.
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
April 25, 2025 at 9:35 AM
Dear Synbio community.
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
Dear Synbio community.
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
April 25, 2025 at 9:35 AM
Dear Synbio community.
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
We are looking for books, YouTube channels, websites etc that is targeted for layman audiences to provide explanations for what we do.
If you know of any such resources could you please provide it in this thread? Maybe we can all use links to such resources for our students🧪
Reposted by Sheila I. Jensen
#invertefest
Please enjoy some art that will be featured in an upcoming exhibition at a local wildlife refuge.
My first since leaving research behind to pursue my arthropod art dreams... in a crashing economy and increasingly authoritarian regime, wee! 😅
LindZeamays.com/printshop
🎨🐡🌱🪳🪲
Please enjoy some art that will be featured in an upcoming exhibition at a local wildlife refuge.
My first since leaving research behind to pursue my arthropod art dreams... in a crashing economy and increasingly authoritarian regime, wee! 😅
LindZeamays.com/printshop
🎨🐡🌱🪳🪲
April 24, 2025 at 9:26 PM
#invertefest
Please enjoy some art that will be featured in an upcoming exhibition at a local wildlife refuge.
My first since leaving research behind to pursue my arthropod art dreams... in a crashing economy and increasingly authoritarian regime, wee! 😅
LindZeamays.com/printshop
🎨🐡🌱🪳🪲
Please enjoy some art that will be featured in an upcoming exhibition at a local wildlife refuge.
My first since leaving research behind to pursue my arthropod art dreams... in a crashing economy and increasingly authoritarian regime, wee! 😅
LindZeamays.com/printshop
🎨🐡🌱🪳🪲
Reposted by Sheila I. Jensen
Cas9 shows trans-cleavage activity and can be used for DNA and RNA detection go.nature.com/3UZYUpx
rdcu.be/ei3mB
rdcu.be/ei3mB
Trans-nuclease activity of Cas9 activated by DNA or RNA target binding - Nature Biotechnology
Cas9 shows trans-cleavage activity and can be used for DNA and RNA detection.
go.nature.com
April 24, 2025 at 1:47 AM
Cas9 shows trans-cleavage activity and can be used for DNA and RNA detection go.nature.com/3UZYUpx
rdcu.be/ei3mB
rdcu.be/ei3mB
Reposted by Sheila I. Jensen
Interested in CRISPR and gene editing? ✂️ 🧬
Join us for the upcoming course designed for PhD students, postdocs, and industry professionals eager to deepen their understanding of #CRISPR technologies and their applications in gene editing.
Sign up here 👇🏽:
training.vib.be/all-training...
Join us for the upcoming course designed for PhD students, postdocs, and industry professionals eager to deepen their understanding of #CRISPR technologies and their applications in gene editing.
Sign up here 👇🏽:
training.vib.be/all-training...
CRISPR in action: practice and theory of genome engineering
This intensive 5-day course provides a comprehensive introduction to CRISPR, covering both theoretical foundations and wet-lab experimental techniques. At the same time, you will have the unique oppor...
training.vib.be
April 15, 2025 at 8:28 AM
Interested in CRISPR and gene editing? ✂️ 🧬
Join us for the upcoming course designed for PhD students, postdocs, and industry professionals eager to deepen their understanding of #CRISPR technologies and their applications in gene editing.
Sign up here 👇🏽:
training.vib.be/all-training...
Join us for the upcoming course designed for PhD students, postdocs, and industry professionals eager to deepen their understanding of #CRISPR technologies and their applications in gene editing.
Sign up here 👇🏽:
training.vib.be/all-training...
Reposted by Sheila I. Jensen
Mathematician and aerospace engineer Mary Jackson was born #OTD in 1921.
Jackson worked at the National Advisory Committee for Aeronautics until it was succeeded by NASA in 1958. She then became the first black woman to work as a NASA engineer. 🧪 🚀 👩🏾🔬
www.nasa.gov/history/mary...
Jackson worked at the National Advisory Committee for Aeronautics until it was succeeded by NASA in 1958. She then became the first black woman to work as a NASA engineer. 🧪 🚀 👩🏾🔬
www.nasa.gov/history/mary...
April 9, 2025 at 8:14 PM
Mathematician and aerospace engineer Mary Jackson was born #OTD in 1921.
Jackson worked at the National Advisory Committee for Aeronautics until it was succeeded by NASA in 1958. She then became the first black woman to work as a NASA engineer. 🧪 🚀 👩🏾🔬
www.nasa.gov/history/mary...
Jackson worked at the National Advisory Committee for Aeronautics until it was succeeded by NASA in 1958. She then became the first black woman to work as a NASA engineer. 🧪 🚀 👩🏾🔬
www.nasa.gov/history/mary...
1/2 New paper by our PhD student Sompot Antimanon, where he uses Pseudomonas putida as a biocatalyst for cinnamic acid production in a process that increase water use efficiency. Sompot reached a TRY of T=143 g/L, R= 2.25 g/L/h, and Y 1.50 g/g glc after 8 recycles.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
High-efficiency water use and process performance for bioproduction of trans-cinnamic acid - Scientific Reports
Scientific Reports - High-efficiency water use and process performance for bioproduction of trans-cinnamic acid
www.nature.com
April 8, 2025 at 5:46 PM
1/2 New paper by our PhD student Sompot Antimanon, where he uses Pseudomonas putida as a biocatalyst for cinnamic acid production in a process that increase water use efficiency. Sompot reached a TRY of T=143 g/L, R= 2.25 g/L/h, and Y 1.50 g/g glc after 8 recycles.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Sheila I. Jensen
Encouraging news I would've missed if it weren't for Liz's weekly update: "The Rutgers University Senate passed a resolution proposing a Mutual Defense Compact in which members of the Big Ten conference will pool funding and legal, policy, and communications capacity and expertise."
More of this!
More of this!
I flew home from #SciTalk25 last night, so this week’s Meeting the Moment debrief was written at altitude, while I watched lightning pulse in thunderclouds.
What’s happening in science & higher ed: buttondown.com/liminalcreat...
Thread to come after some much needed coffee and hiking.
What’s happening in science & higher ed: buttondown.com/liminalcreat...
Thread to come after some much needed coffee and hiking.
April 7, 2025 at 12:21 AM
Encouraging news I would've missed if it weren't for Liz's weekly update: "The Rutgers University Senate passed a resolution proposing a Mutual Defense Compact in which members of the Big Ten conference will pool funding and legal, policy, and communications capacity and expertise."
More of this!
More of this!