Ruben Vazquez Uribe
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ruvaur.bsky.social
Ruben Vazquez Uribe
@ruvaur.bsky.social
Scientist at KU-Leuven VIB Center for Microbiology 🇧🇪, Previously co-PI at DTU Novo Nordisk Foundation Center for Biosustainability 🇩🇰

Microbial ecology | CRISPR | Synthetic biology | Fermented foods | Biosustainability

www.rvuribe.com
Pinned
🎉 Excited to share our latest work, now published in @naturecomms.bsky.social ! 🍾 We developed a scalable approach combining metagenomics & culturomics to enhance gut microbe cultivation, enriching rare taxa & relevant metabolic pathways. 📖 Read more: www.nature.com/articles/s41...
Metagenome-guided culturomics for the targeted enrichment of gut microbes - Nature Communications
Cultivation challenges hinder the exploration of the gut microbiota. Here, authors combine whole metagenome sequencing with culturomics to selectively enrich for specific taxa, uncovering medium modif...
www.nature.com
I really enjoyed being on the Called to Science podcast to talk about my journey as a scientist 🧑🏽‍🔬🧬

We discussed my passion for microbes, moving across countries, microbiology & sustainability (incl. HealthFerm), and finding purpose in science.

🎧 link below👇🏽
#Microbiology #SciencePodcast
NEW | Episode 6: Ruben Vazquez Uribe - Science with values at its core #podcast
YouTube video by VIB
youtu.be
October 19, 2025 at 1:02 PM
Reposted by Ruben Vazquez Uribe
BREAKING: The Nobel Prize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks”

Stay tuned for more.
#NobelPrize
October 8, 2025 at 9:49 AM
Reposted by Ruben Vazquez Uribe
Another great day at #UEGWeek 2025! 🎉Congratulations to our colleague Jorge Vazquez Castellanos for presenting his exciting work on microbial dysbiosis, inflammation, and the gut–brain axis in IBS at the United European Gastroenterology Week in Berlin🇩🇪 @myueg.bsky.social @vibmicrobes.bsky.social
October 7, 2025 at 10:01 AM
Reposted by Ruben Vazquez Uribe
GTDB release 10 based on RefSeq 226 (R10-RS226) is live at gtdb.ecogenomic.org. This release covers 732,475 genomes (22% increase) and has 143,6141 species clusters (37% increase). Release notes at: forum.gtdb.ecogenomic.org/t/announcing.... Release statistics at: gtdb.ecogenomic.org/stats/r226.
GTDB - Genome Taxonomy Database
The Genome Taxonomy Database (GTDB) is an initiative to establish a standardised microbial taxonomy based on genome phylogeny.
gtdb.ecogenomic.org
April 18, 2025 at 7:13 PM
Reposted by Ruben Vazquez Uribe
Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...
September 15, 2025 at 9:27 AM
Reposted by Ruben Vazquez Uribe
Exams = stress. 📚 Our new study shows that a probiotic strain (L. rhamnosus CNCM I-3690) modulated the gut microbiome during academic stress, with ties to lower anxiety.

🔗 Vázquez-Castellanos et al. doi.org/10.1038/s415...
Probiotic-mediated modulation of gut microbiome in students exposed to academic stress: a randomized controlled trial - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Probiotic-mediated modulation of gut microbiome in students exposed to academic stress: a randomized controlled trial
doi.org
September 1, 2025 at 7:52 AM
Reposted by Ruben Vazquez Uribe
Bacteria expressing an anti-tumor cytokine act as a potent cancer immunotherapy go.nature.com/4ettzUR
rdcu.be/eBeA1
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses - Nature Biotechnology
Bacteria expressing an anti-tumor cytokine act as a potent cancer immunotherapy.
go.nature.com
August 21, 2025 at 11:46 AM
R.I.P. 🪦 Tesla @Mexico City
August 17, 2025 at 1:11 PM
Reposted by Ruben Vazquez Uribe
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 3:15 PM
Reposted by Ruben Vazquez Uribe
Reposted by Ruben Vazquez Uribe
@skamrad.bsky.social @kiranrpatil.bsky.social show xenobiotics impact growth of gut bacteria and their metabolic homeostasis by affecting amine metabolism ➡️ www.embopress.org/doi/full/10....
July 3, 2025 at 12:44 PM
Reposted by Ruben Vazquez Uribe
The paper is definitely worth a read—and if you're curious for a glimpse behind the scenes of how the story developed, don’t miss this short blog post by Anne and Jacobo.
communities.springernature.com/posts/silent...
Silent influencer: How non-antibiotics tip the microbial balance of the gut microbiome
Some human-targeted drugs can alter gut microbes, creating a favorable environment for pathogens like Salmonella to thrive.
communities.springernature.com
July 16, 2025 at 9:20 PM
Reposted by Ruben Vazquez Uribe
Finally online!
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Non-antibiotics disrupt colonization resistance against enteropathogens
Nature - Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of...
rdcu.be
July 16, 2025 at 9:20 PM
Reposted by Ruben Vazquez Uribe
Great timing a couple of weeks ago where I got to present our work on the discovery of new phage DNA modifications and their implications for phage defence at #EESMicrobiology one hour after the paper came out in @cp-cellhostmicrobe.bsky.social! Fantastic conference!
July 13, 2025 at 4:16 AM
Reposted by Ruben Vazquez Uribe
We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...
June 30, 2025 at 2:34 PM
Reposted by Ruben Vazquez Uribe
Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD in our group. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - specific adhesion, juxtacrine signalling and more. www.cell.com/cell/fulltex...
Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling
By designing synthetic toolkits for contact-based signaling (MARS) and cell-cell adhesion (SATURN), we program yeast to form multicellular structures and perform complex tasks, like building logic cir...
www.cell.com
July 11, 2025 at 3:01 PM
Reposted by Ruben Vazquez Uribe
🚀 New ERC Classes video released! Thinking of applying to the open call for ERC Synergy grants?

Learn how to apply, build your team, and prepare for the evaluation steps.

▶️ Watch the full video now 👉 youtu.be/qGKoTFqs8Eg

📥 Also new today: Info for #ERCSyG applicants 👉 europa.eu/!w7gPHV
July 11, 2025 at 1:27 PM
Reposted by Ruben Vazquez Uribe
If you're feeling low on science mojo (if you are not, read more), I recommend talking to a room of excited high schoolers/ undergraduates about science & its future.

I was a vampire for hope & enthusiasm today in the Pathways program started by the late Beverly Torok-Storb @fredhutch.bsky.social
July 11, 2025 at 7:29 PM
Reposted by Ruben Vazquez Uribe
We are immensely proud of our postdoctoral researcher Doris van Bergeijk @dorisvanbergeijk.bsky.social for being awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social 🎉👏 Her hard work and dedication is truly inspiring. 🧠🦠 Huge congrats Doris! 💪🌟 @vibmicrobes.bsky.social
🎉 Proud to announce that Doris van Bergeijk, postdoctoral researcher at @raeslab.org ( @kuleuvenuniversity.bsky.social, @viblifesciences.bsky.social), has been awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social, to study how the gut microbiome can shape our mental health. 🧠🦠
May 27, 2025 at 11:10 AM
Big big congratulation @dorisvanbergeijk.bsky.social !!
🎉 Proud to announce that Doris van Bergeijk, postdoctoral researcher at @raeslab.org ( @kuleuvenuniversity.bsky.social, @viblifesciences.bsky.social), has been awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social, to study how the gut microbiome can shape our mental health. 🧠🦠
May 27, 2025 at 10:42 AM
Reposted by Ruben Vazquez Uribe
🎉 Proud to announce that Doris van Bergeijk, postdoctoral researcher at @raeslab.org ( @kuleuvenuniversity.bsky.social, @viblifesciences.bsky.social), has been awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social, to study how the gut microbiome can shape our mental health. 🧠🦠
May 27, 2025 at 10:08 AM
Reposted by Ruben Vazquez Uribe
Excited to welcome our new Agilent Revident Q-TOF! We’re developing new approaches combining mass spectrometry and enzyme assays to study microbial interactions and carbon sequestration. We're hiring postdocs — reach out if interested!

pontrellilab.sites.vib.be/en
April 28, 2025 at 11:17 AM
Reposted by Ruben Vazquez Uribe
#MVIF 39 recordings are now available!

Huge thanks to Adeshile Oluwatosin for putting together all the talks, available on both platforms:

@cassyni.bsky.social ▶️ cassyni.com/s/mvif-39

#YouTube ▶️ youtube.com/playlist?lis...

Enjoy!
MVIF.39 - 5th May 2025 - YouTube
youtube.com
May 12, 2025 at 9:10 AM
Reposted by Ruben Vazquez Uribe
CRISPR-associated transposase variants with enhanced gene integration were generated via phage-assisted continuous evolution, enabling insertion of large DNA cargos at therapeutically relevant genomic sites in human cells without double-strand breaks. #NBThighlight www.science.org/doi/10.1126/...
Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase
Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life sciences. CRISP...
www.science.org
May 16, 2025 at 11:46 AM
Reposted by Ruben Vazquez Uribe
In @nature.com we describe the use of scalable #proteinengineering & #machinelearning to predict millions of bespoke CRISPR enzymes, offering safer & more efficient genome editing tools 🧬🖥️ @rachelsilverstein9.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social
www.nature.com/articles/s41...
Custom CRISPR—Cas9 PAM variants via scalable engineering and machine learning - Nature
Nature - Custom CRISPR—Cas9 PAM variants via scalable engineering and machine learning
www.nature.com
April 22, 2025 at 8:57 PM