Ruben Vazquez Uribe
@ruvaur.bsky.social
Scientist at KU-Leuven VIB Center for Microbiology 🇧🇪, Previously co-PI at DTU Novo Nordisk Foundation Center for Biosustainability 🇩🇰
Microbial ecology | CRISPR | Synthetic biology | Fermented foods | Biosustainability
www.rvuribe.com
Microbial ecology | CRISPR | Synthetic biology | Fermented foods | Biosustainability
www.rvuribe.com
Pinned
Ruben Vazquez Uribe
@ruvaur.bsky.social
· Jan 17
Metagenome-guided culturomics for the targeted enrichment of gut microbes - Nature Communications
Cultivation challenges hinder the exploration of the gut microbiota. Here, authors combine whole metagenome sequencing with culturomics to selectively enrich for specific taxa, uncovering medium modif...
www.nature.com
🎉 Excited to share our latest work, now published in @naturecomms.bsky.social ! 🍾 We developed a scalable approach combining metagenomics & culturomics to enhance gut microbe cultivation, enriching rare taxa & relevant metabolic pathways. 📖 Read more: www.nature.com/articles/s41...
I really enjoyed being on the Called to Science podcast to talk about my journey as a scientist 🧑🏽🔬🧬
We discussed my passion for microbes, moving across countries, microbiology & sustainability (incl. HealthFerm), and finding purpose in science.
🎧 link below👇🏽
#Microbiology #SciencePodcast
We discussed my passion for microbes, moving across countries, microbiology & sustainability (incl. HealthFerm), and finding purpose in science.
🎧 link below👇🏽
#Microbiology #SciencePodcast
NEW | Episode 6: Ruben Vazquez Uribe - Science with values at its core #podcast
YouTube video by VIB
youtu.be
October 19, 2025 at 1:02 PM
I really enjoyed being on the Called to Science podcast to talk about my journey as a scientist 🧑🏽🔬🧬
We discussed my passion for microbes, moving across countries, microbiology & sustainability (incl. HealthFerm), and finding purpose in science.
🎧 link below👇🏽
#Microbiology #SciencePodcast
We discussed my passion for microbes, moving across countries, microbiology & sustainability (incl. HealthFerm), and finding purpose in science.
🎧 link below👇🏽
#Microbiology #SciencePodcast
Reposted by Ruben Vazquez Uribe
BREAKING: The Nobel Prize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks”
Stay tuned for more.
#NobelPrize
Stay tuned for more.
#NobelPrize
October 8, 2025 at 9:49 AM
BREAKING: The Nobel Prize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks”
Stay tuned for more.
#NobelPrize
Stay tuned for more.
#NobelPrize
Reposted by Ruben Vazquez Uribe
Another great day at #UEGWeek 2025! 🎉Congratulations to our colleague Jorge Vazquez Castellanos for presenting his exciting work on microbial dysbiosis, inflammation, and the gut–brain axis in IBS at the United European Gastroenterology Week in Berlin🇩🇪 @myueg.bsky.social @vibmicrobes.bsky.social
October 7, 2025 at 10:01 AM
Another great day at #UEGWeek 2025! 🎉Congratulations to our colleague Jorge Vazquez Castellanos for presenting his exciting work on microbial dysbiosis, inflammation, and the gut–brain axis in IBS at the United European Gastroenterology Week in Berlin🇩🇪 @myueg.bsky.social @vibmicrobes.bsky.social
Reposted by Ruben Vazquez Uribe
GTDB release 10 based on RefSeq 226 (R10-RS226) is live at gtdb.ecogenomic.org. This release covers 732,475 genomes (22% increase) and has 143,6141 species clusters (37% increase). Release notes at: forum.gtdb.ecogenomic.org/t/announcing.... Release statistics at: gtdb.ecogenomic.org/stats/r226.
GTDB - Genome Taxonomy Database
The Genome Taxonomy Database (GTDB) is an initiative to establish a standardised microbial taxonomy based on genome phylogeny.
gtdb.ecogenomic.org
April 18, 2025 at 7:13 PM
GTDB release 10 based on RefSeq 226 (R10-RS226) is live at gtdb.ecogenomic.org. This release covers 732,475 genomes (22% increase) and has 143,6141 species clusters (37% increase). Release notes at: forum.gtdb.ecogenomic.org/t/announcing.... Release statistics at: gtdb.ecogenomic.org/stats/r226.
Reposted by Ruben Vazquez Uribe
Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...
September 15, 2025 at 9:27 AM
Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...
Reposted by Ruben Vazquez Uribe
Exams = stress. 📚 Our new study shows that a probiotic strain (L. rhamnosus CNCM I-3690) modulated the gut microbiome during academic stress, with ties to lower anxiety.
🔗 Vázquez-Castellanos et al. doi.org/10.1038/s415...
🔗 Vázquez-Castellanos et al. doi.org/10.1038/s415...
Probiotic-mediated modulation of gut microbiome in students exposed to academic stress: a randomized controlled trial - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Probiotic-mediated modulation of gut microbiome in students exposed to academic stress: a randomized controlled trial
doi.org
September 1, 2025 at 7:52 AM
Exams = stress. 📚 Our new study shows that a probiotic strain (L. rhamnosus CNCM I-3690) modulated the gut microbiome during academic stress, with ties to lower anxiety.
🔗 Vázquez-Castellanos et al. doi.org/10.1038/s415...
🔗 Vázquez-Castellanos et al. doi.org/10.1038/s415...
Reposted by Ruben Vazquez Uribe
Bacteria expressing an anti-tumor cytokine act as a potent cancer immunotherapy go.nature.com/4ettzUR
rdcu.be/eBeA1
rdcu.be/eBeA1
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses - Nature Biotechnology
Bacteria expressing an anti-tumor cytokine act as a potent cancer immunotherapy.
go.nature.com
August 21, 2025 at 11:46 AM
Bacteria expressing an anti-tumor cytokine act as a potent cancer immunotherapy go.nature.com/4ettzUR
rdcu.be/eBeA1
rdcu.be/eBeA1
R.I.P. 🪦 Tesla @Mexico City
August 17, 2025 at 1:11 PM
R.I.P. 🪦 Tesla @Mexico City
Reposted by Ruben Vazquez Uribe
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 3:15 PM
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
Reposted by Ruben Vazquez Uribe
Eco-evolutionary robustness of wild bacterial communities to experimental perturbation
#ISMEJournal by @duhitasant.bsky.social et al from @timbarra.bsky.social
with Tom Bell, @kayla-king.bsky.social
academic.oup.com/ismej/advanc...
#ISMEJournal by @duhitasant.bsky.social et al from @timbarra.bsky.social
with Tom Bell, @kayla-king.bsky.social
academic.oup.com/ismej/advanc...
Eco-evolutionary robustness of wild bacterial communities to experimental perturbation
Abstract. Most knowledge about bacterial evolution and ecological interactions comes from laboratory studies. One difference between the wild and most labo
academic.oup.com
July 24, 2025 at 5:27 AM
Eco-evolutionary robustness of wild bacterial communities to experimental perturbation
#ISMEJournal by @duhitasant.bsky.social et al from @timbarra.bsky.social
with Tom Bell, @kayla-king.bsky.social
academic.oup.com/ismej/advanc...
#ISMEJournal by @duhitasant.bsky.social et al from @timbarra.bsky.social
with Tom Bell, @kayla-king.bsky.social
academic.oup.com/ismej/advanc...
Reposted by Ruben Vazquez Uribe
@skamrad.bsky.social @kiranrpatil.bsky.social show xenobiotics impact growth of gut bacteria and their metabolic homeostasis by affecting amine metabolism ➡️ www.embopress.org/doi/full/10....
July 3, 2025 at 12:44 PM
@skamrad.bsky.social @kiranrpatil.bsky.social show xenobiotics impact growth of gut bacteria and their metabolic homeostasis by affecting amine metabolism ➡️ www.embopress.org/doi/full/10....
Reposted by Ruben Vazquez Uribe
The paper is definitely worth a read—and if you're curious for a glimpse behind the scenes of how the story developed, don’t miss this short blog post by Anne and Jacobo.
communities.springernature.com/posts/silent...
communities.springernature.com/posts/silent...
Silent influencer: How non-antibiotics tip the microbial balance of the gut microbiome
Some human-targeted drugs can alter gut microbes, creating a favorable environment for pathogens like Salmonella to thrive.
communities.springernature.com
July 16, 2025 at 9:20 PM
The paper is definitely worth a read—and if you're curious for a glimpse behind the scenes of how the story developed, don’t miss this short blog post by Anne and Jacobo.
communities.springernature.com/posts/silent...
communities.springernature.com/posts/silent...
Reposted by Ruben Vazquez Uribe
Finally online!
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Non-antibiotics disrupt colonization resistance against enteropathogens
Nature - Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of...
rdcu.be
July 16, 2025 at 9:20 PM
Finally online!
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
Reposted by Ruben Vazquez Uribe
Great timing a couple of weeks ago where I got to present our work on the discovery of new phage DNA modifications and their implications for phage defence at #EESMicrobiology one hour after the paper came out in @cp-cellhostmicrobe.bsky.social! Fantastic conference!
July 13, 2025 at 4:16 AM
Great timing a couple of weeks ago where I got to present our work on the discovery of new phage DNA modifications and their implications for phage defence at #EESMicrobiology one hour after the paper came out in @cp-cellhostmicrobe.bsky.social! Fantastic conference!
Reposted by Ruben Vazquez Uribe
We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...
June 30, 2025 at 2:34 PM
We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...
Reposted by Ruben Vazquez Uribe
Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD in our group. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - specific adhesion, juxtacrine signalling and more. www.cell.com/cell/fulltex...
Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling
By designing synthetic toolkits for contact-based signaling (MARS) and cell-cell adhesion
(SATURN), we program yeast to form multicellular structures and perform complex tasks,
like building logic cir...
www.cell.com
July 11, 2025 at 3:01 PM
Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD in our group. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - specific adhesion, juxtacrine signalling and more. www.cell.com/cell/fulltex...
Reposted by Ruben Vazquez Uribe
🚀 New ERC Classes video released! Thinking of applying to the open call for ERC Synergy grants?
Learn how to apply, build your team, and prepare for the evaluation steps.
▶️ Watch the full video now 👉 youtu.be/qGKoTFqs8Eg
📥 Also new today: Info for #ERCSyG applicants 👉 europa.eu/!w7gPHV
Learn how to apply, build your team, and prepare for the evaluation steps.
▶️ Watch the full video now 👉 youtu.be/qGKoTFqs8Eg
📥 Also new today: Info for #ERCSyG applicants 👉 europa.eu/!w7gPHV
July 11, 2025 at 1:27 PM
🚀 New ERC Classes video released! Thinking of applying to the open call for ERC Synergy grants?
Learn how to apply, build your team, and prepare for the evaluation steps.
▶️ Watch the full video now 👉 youtu.be/qGKoTFqs8Eg
📥 Also new today: Info for #ERCSyG applicants 👉 europa.eu/!w7gPHV
Learn how to apply, build your team, and prepare for the evaluation steps.
▶️ Watch the full video now 👉 youtu.be/qGKoTFqs8Eg
📥 Also new today: Info for #ERCSyG applicants 👉 europa.eu/!w7gPHV
Reposted by Ruben Vazquez Uribe
If you're feeling low on science mojo (if you are not, read more), I recommend talking to a room of excited high schoolers/ undergraduates about science & its future.
I was a vampire for hope & enthusiasm today in the Pathways program started by the late Beverly Torok-Storb @fredhutch.bsky.social
I was a vampire for hope & enthusiasm today in the Pathways program started by the late Beverly Torok-Storb @fredhutch.bsky.social
July 11, 2025 at 7:29 PM
If you're feeling low on science mojo (if you are not, read more), I recommend talking to a room of excited high schoolers/ undergraduates about science & its future.
I was a vampire for hope & enthusiasm today in the Pathways program started by the late Beverly Torok-Storb @fredhutch.bsky.social
I was a vampire for hope & enthusiasm today in the Pathways program started by the late Beverly Torok-Storb @fredhutch.bsky.social
Reposted by Ruben Vazquez Uribe
We are immensely proud of our postdoctoral researcher Doris van Bergeijk @dorisvanbergeijk.bsky.social for being awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social 🎉👏 Her hard work and dedication is truly inspiring. 🧠🦠 Huge congrats Doris! 💪🌟 @vibmicrobes.bsky.social
🎉 Proud to announce that Doris van Bergeijk, postdoctoral researcher at @raeslab.org ( @kuleuvenuniversity.bsky.social, @viblifesciences.bsky.social), has been awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social, to study how the gut microbiome can shape our mental health. 🧠🦠
May 27, 2025 at 11:10 AM
We are immensely proud of our postdoctoral researcher Doris van Bergeijk @dorisvanbergeijk.bsky.social for being awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social 🎉👏 Her hard work and dedication is truly inspiring. 🧠🦠 Huge congrats Doris! 💪🌟 @vibmicrobes.bsky.social
Big big congratulation @dorisvanbergeijk.bsky.social !!
🎉 Proud to announce that Doris van Bergeijk, postdoctoral researcher at @raeslab.org ( @kuleuvenuniversity.bsky.social, @viblifesciences.bsky.social), has been awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social, to study how the gut microbiome can shape our mental health. 🧠🦠
May 27, 2025 at 10:42 AM
Big big congratulation @dorisvanbergeijk.bsky.social !!
Reposted by Ruben Vazquez Uribe
🎉 Proud to announce that Doris van Bergeijk, postdoctoral researcher at @raeslab.org ( @kuleuvenuniversity.bsky.social, @viblifesciences.bsky.social), has been awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social, to study how the gut microbiome can shape our mental health. 🧠🦠
May 27, 2025 at 10:08 AM
🎉 Proud to announce that Doris van Bergeijk, postdoctoral researcher at @raeslab.org ( @kuleuvenuniversity.bsky.social, @viblifesciences.bsky.social), has been awarded a Junior Postdoctoral Fellowship by @fwovlaanderen.bsky.social, to study how the gut microbiome can shape our mental health. 🧠🦠
Reposted by Ruben Vazquez Uribe
Excited to welcome our new Agilent Revident Q-TOF! We’re developing new approaches combining mass spectrometry and enzyme assays to study microbial interactions and carbon sequestration. We're hiring postdocs — reach out if interested!
pontrellilab.sites.vib.be/en
pontrellilab.sites.vib.be/en
April 28, 2025 at 11:17 AM
Excited to welcome our new Agilent Revident Q-TOF! We’re developing new approaches combining mass spectrometry and enzyme assays to study microbial interactions and carbon sequestration. We're hiring postdocs — reach out if interested!
pontrellilab.sites.vib.be/en
pontrellilab.sites.vib.be/en
Reposted by Ruben Vazquez Uribe
#MVIF 39 recordings are now available!
Huge thanks to Adeshile Oluwatosin for putting together all the talks, available on both platforms:
@cassyni.bsky.social ▶️ cassyni.com/s/mvif-39
#YouTube ▶️ youtube.com/playlist?lis...
Enjoy!
Huge thanks to Adeshile Oluwatosin for putting together all the talks, available on both platforms:
@cassyni.bsky.social ▶️ cassyni.com/s/mvif-39
#YouTube ▶️ youtube.com/playlist?lis...
Enjoy!
MVIF.39 - 5th May 2025 - YouTube
youtube.com
May 12, 2025 at 9:10 AM
#MVIF 39 recordings are now available!
Huge thanks to Adeshile Oluwatosin for putting together all the talks, available on both platforms:
@cassyni.bsky.social ▶️ cassyni.com/s/mvif-39
#YouTube ▶️ youtube.com/playlist?lis...
Enjoy!
Huge thanks to Adeshile Oluwatosin for putting together all the talks, available on both platforms:
@cassyni.bsky.social ▶️ cassyni.com/s/mvif-39
#YouTube ▶️ youtube.com/playlist?lis...
Enjoy!
Reposted by Ruben Vazquez Uribe
CRISPR-associated transposase variants with enhanced gene integration were generated via phage-assisted continuous evolution, enabling insertion of large DNA cargos at therapeutically relevant genomic sites in human cells without double-strand breaks. #NBThighlight www.science.org/doi/10.1126/...
Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase
Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life sciences. CRISP...
www.science.org
May 16, 2025 at 11:46 AM
CRISPR-associated transposase variants with enhanced gene integration were generated via phage-assisted continuous evolution, enabling insertion of large DNA cargos at therapeutically relevant genomic sites in human cells without double-strand breaks. #NBThighlight www.science.org/doi/10.1126/...
Reposted by Ruben Vazquez Uribe
In @nature.com we describe the use of scalable #proteinengineering & #machinelearning to predict millions of bespoke CRISPR enzymes, offering safer & more efficient genome editing tools 🧬🖥️ @rachelsilverstein9.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Custom CRISPR—Cas9 PAM variants via scalable engineering and machine learning - Nature
Nature - Custom CRISPR—Cas9 PAM variants via scalable engineering and machine learning
www.nature.com
April 22, 2025 at 8:57 PM
In @nature.com we describe the use of scalable #proteinengineering & #machinelearning to predict millions of bespoke CRISPR enzymes, offering safer & more efficient genome editing tools 🧬🖥️ @rachelsilverstein9.bsky.social @mgbresearch.bsky.social @harvardmed.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...