Pablo Ivan Nikel
@pabnik.bsky.social
Professor DTU Biosustain · Proud PI @labnikel.bsky.social · SynBio · Metabolic Engineering · @novo-nordisk.bsky.social Ascending Investigator & Distinguished Innovator · He/him🏳️🌈
Reposted by Pablo Ivan Nikel
this is also a contribution to the Scientists' Warning to Humanity series
@scientistswarning.bsky.social
@scientistswarning.bsky.social
Happy to post our latest paper:
doi.org/10.1111/1751...
Biases accumulate with age, so it is essential to begin teaching critical thinking as early as possible. The problems are HOW, given the complexity of its theory, and IN WHAT EDUCATIONAL CONTEXT? The solutions we propose in this paper are...
doi.org/10.1111/1751...
Biases accumulate with age, so it is essential to begin teaching critical thinking as early as possible. The problems are HOW, given the complexity of its theory, and IN WHAT EDUCATIONAL CONTEXT? The solutions we propose in this paper are...
December 16, 2025 at 9:24 AM
this is also a contribution to the Scientists' Warning to Humanity series
@scientistswarning.bsky.social
@scientistswarning.bsky.social
Reposted by Pablo Ivan Nikel
Happy to post our latest paper:
doi.org/10.1111/1751...
Biases accumulate with age, so it is essential to begin teaching critical thinking as early as possible. The problems are HOW, given the complexity of its theory, and IN WHAT EDUCATIONAL CONTEXT? The solutions we propose in this paper are...
doi.org/10.1111/1751...
Biases accumulate with age, so it is essential to begin teaching critical thinking as early as possible. The problems are HOW, given the complexity of its theory, and IN WHAT EDUCATIONAL CONTEXT? The solutions we propose in this paper are...
December 16, 2025 at 9:15 AM
Happy to post our latest paper:
doi.org/10.1111/1751...
Biases accumulate with age, so it is essential to begin teaching critical thinking as early as possible. The problems are HOW, given the complexity of its theory, and IN WHAT EDUCATIONAL CONTEXT? The solutions we propose in this paper are...
doi.org/10.1111/1751...
Biases accumulate with age, so it is essential to begin teaching critical thinking as early as possible. The problems are HOW, given the complexity of its theory, and IN WHAT EDUCATIONAL CONTEXT? The solutions we propose in this paper are...
Reposted by Pablo Ivan Nikel
Microbes determine the health of all other organisms and that of the planet. They were our ancestors and are our cousins. They are life and sustain it.
Microbes are life, the biological core of One Health and Health in All Policies url: academic.oup.com/microlife/ar...
Microbes are life, the biological core of One Health and Health in All Policies url: academic.oup.com/microlife/ar...
Microbes are life, the biological core of One Health and Health in All Policies
The World Health Organization (WHO) is promoting the operative concept of “Health in All Policies” (HiAP; https://iris.who.int/bitstream/handle/10665/11263
academic.oup.com
December 7, 2025 at 9:01 AM
Microbes determine the health of all other organisms and that of the planet. They were our ancestors and are our cousins. They are life and sustain it.
Microbes are life, the biological core of One Health and Health in All Policies url: academic.oup.com/microlife/ar...
Microbes are life, the biological core of One Health and Health in All Policies url: academic.oup.com/microlife/ar...
Reposted by Pablo Ivan Nikel
So excited that the theme of LGBT+ History Month UK 2026 is 'Science and Innovation,' with super badge designed by @canopyrobin.com! 🧬🏳️⚧️🔭🏳️🌈🚆
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
LGBT+ History Month 2026 - LGBT+ History Month
If you’d like to donate to support our work, click here to donate via PayPal. Free Schools Presentation For 2026 we are able to offer free LGBT+ History Month presentations for secondary schools, prid...
lgbtplushistorymonth.co.uk
November 7, 2025 at 9:01 PM
So excited that the theme of LGBT+ History Month UK 2026 is 'Science and Innovation,' with super badge designed by @canopyrobin.com! 🧬🏳️⚧️🔭🏳️🌈🚆
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
Growth-coupled microbial biosynthesis of the animal pigment xanthommatin — Led by Leah Bushin, featuring M. Gracia Alvan, @danielvolke.bsky.social @oscarpuiggene.bsky.social in a fantastic collaboration w/Brad Moore @labnikel.bsky.social @natbiotech.nature.com 🦑
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 3, 2025 at 12:49 PM
Growth-coupled microbial biosynthesis of the animal pigment xanthommatin — Led by Leah Bushin, featuring M. Gracia Alvan, @danielvolke.bsky.social @oscarpuiggene.bsky.social in a fantastic collaboration w/Brad Moore @labnikel.bsky.social @natbiotech.nature.com 🦑
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Pablo Ivan Nikel
🚨 New paper in mBio!
We established strict formatotrophic & methylotrophic growth in engineered Pseudomonas putida via the reductive glycine pathway (rGlyP). journals.asm.org/doi/full/10....
Here’s a teaser of how we did it 🧵👇1/5
We established strict formatotrophic & methylotrophic growth in engineered Pseudomonas putida via the reductive glycine pathway (rGlyP). journals.asm.org/doi/full/10....
Here’s a teaser of how we did it 🧵👇1/5
Synthetic C1 metabolism in Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway | mBio
Soluble C1 feedstocks, such as formate and methanol, have gained attention as sustainable substrates for biotechnology, with the potential to reduce greenhouse gas emissions and reliance on sugar-based resources. Despite their promise, the metabolic ...
journals.asm.org
August 22, 2025 at 10:19 AM
🚨 New paper in mBio!
We established strict formatotrophic & methylotrophic growth in engineered Pseudomonas putida via the reductive glycine pathway (rGlyP). journals.asm.org/doi/full/10....
Here’s a teaser of how we did it 🧵👇1/5
We established strict formatotrophic & methylotrophic growth in engineered Pseudomonas putida via the reductive glycine pathway (rGlyP). journals.asm.org/doi/full/10....
Here’s a teaser of how we did it 🧵👇1/5
Reposted by Pablo Ivan Nikel
3/4 Our perspective lays out:
1️⃣ A blueprint for designing next-gen synthetic C1 microbes
2️⃣ A roadmap for engineering P. putida into an autotrophic chassis
3️⃣ A circular carbon economy vision, revalorizing CO₂ + waste streams
📊 Together, these steps connect design → engineering → sustainability.
1️⃣ A blueprint for designing next-gen synthetic C1 microbes
2️⃣ A roadmap for engineering P. putida into an autotrophic chassis
3️⃣ A circular carbon economy vision, revalorizing CO₂ + waste streams
📊 Together, these steps connect design → engineering → sustainability.
October 8, 2025 at 9:13 AM
3/4 Our perspective lays out:
1️⃣ A blueprint for designing next-gen synthetic C1 microbes
2️⃣ A roadmap for engineering P. putida into an autotrophic chassis
3️⃣ A circular carbon economy vision, revalorizing CO₂ + waste streams
📊 Together, these steps connect design → engineering → sustainability.
1️⃣ A blueprint for designing next-gen synthetic C1 microbes
2️⃣ A roadmap for engineering P. putida into an autotrophic chassis
3️⃣ A circular carbon economy vision, revalorizing CO₂ + waste streams
📊 Together, these steps connect design → engineering → sustainability.
Reposted by Pablo Ivan Nikel
🚀 Thrilled to share our new Nature Communications article:
“A blueprint for designing the next-generation of synthetic C1 microbes”
We propose a framework to unlock sustainable, carbon-efficient biomanufacturing using non-canonical hosts.
🔗 www.nature.com/articles/s41... A short 🧵1/4
“A blueprint for designing the next-generation of synthetic C1 microbes”
We propose a framework to unlock sustainable, carbon-efficient biomanufacturing using non-canonical hosts.
🔗 www.nature.com/articles/s41... A short 🧵1/4
A blueprint for designing the next-generation of synthetic C1 microbes - Nature Communications
Synthetic one-carbon assimilation could contribute to a more sustainable and circular carbon economy, but much work in this field has focused on model microorganisms. Here the authors provide their perspective on the potential value of non-model microbes, and how that potential could be realised.
www.nature.com
October 8, 2025 at 9:10 AM
🚀 Thrilled to share our new Nature Communications article:
“A blueprint for designing the next-generation of synthetic C1 microbes”
We propose a framework to unlock sustainable, carbon-efficient biomanufacturing using non-canonical hosts.
🔗 www.nature.com/articles/s41... A short 🧵1/4
“A blueprint for designing the next-generation of synthetic C1 microbes”
We propose a framework to unlock sustainable, carbon-efficient biomanufacturing using non-canonical hosts.
🔗 www.nature.com/articles/s41... A short 🧵1/4
A blueprint for designing the next-generation of #synthetic C1 #microbes @natureportfolio.nature.com / We outline how to engineer non-canonical hosts, apply modeling & C1-inducible promoters & integrate sustainability metrics for carbon-efficient #biomanufacturing
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A blueprint for designing the next-generation of synthetic C1 microbes - Nature Communications
Synthetic one-carbon assimilation could contribute to a more sustainable and circular carbon economy, but much work in this field has focused on model microorganisms. Here the authors provide their perspective on the potential value of non-model microbes, and how that potential could be realised.
www.nature.com
October 3, 2025 at 1:34 PM
A blueprint for designing the next-generation of #synthetic C1 #microbes @natureportfolio.nature.com / We outline how to engineer non-canonical hosts, apply modeling & C1-inducible promoters & integrate sustainability metrics for carbon-efficient #biomanufacturing
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The very 1st #Course on #SynBio & #Metabolic #Engineering of #Pseudomonas at Cold Spring Harbor Asia successfully completed in Suzhou, #China! Excellent group of students & lecturers, w/time for culture, food & stand-up paddling alongside the science—thanks to all who participated & stay tuned 4+!
September 24, 2025 at 8:34 AM
The very 1st #Course on #SynBio & #Metabolic #Engineering of #Pseudomonas at Cold Spring Harbor Asia successfully completed in Suzhou, #China! Excellent group of students & lecturers, w/time for culture, food & stand-up paddling alongside the science—thanks to all who participated & stay tuned 4+!
Reposted by Pablo Ivan Nikel
Welcome to the social media account of the International Microbiology Literacy Initiative (IMiLI). Nearly 1,000 researchers freely contribute to the IMiLI project integrating microbiology into education providing downloadable resources for all. Explore at imili.org
September 23, 2025 at 6:45 PM
Welcome to the social media account of the International Microbiology Literacy Initiative (IMiLI). Nearly 1,000 researchers freely contribute to the IMiLI project integrating microbiology into education providing downloadable resources for all. Explore at imili.org
Reposted by Pablo Ivan Nikel
Who is afraid of HGT? True, antibiotic resistances disseminate through it. But we can also leverage the same channels for spreading good stuff at a very large scale and fortifying the env microbiome with beneficial activities www.biorxiv.org/content/10.1... by Victor Maull & @ricardsole.bsky.social
Synthetic Horizontal Gene Transfer for Ecosystem Restoration
Restoring endangered ecosystems has become a pressing issue as the effects of global warming continue to harm existing communities. Over the last decade, several studies have suggested the use of synt...
www.biorxiv.org
September 24, 2025 at 6:34 AM
Who is afraid of HGT? True, antibiotic resistances disseminate through it. But we can also leverage the same channels for spreading good stuff at a very large scale and fortifying the env microbiome with beneficial activities www.biorxiv.org/content/10.1... by Victor Maull & @ricardsole.bsky.social
Reposted by Pablo Ivan Nikel
We are deeply saddened by the news that Andrew D. Hanson (@adhansonlab.bsky.social) is no longer with us. He was an exceptional scientist, mentor, and leader in multiple fields. He constantly reminded us that over-promising would backfire. Rest in peace, Andrew.
September 3, 2025 at 5:00 AM
We are deeply saddened by the news that Andrew D. Hanson (@adhansonlab.bsky.social) is no longer with us. He was an exceptional scientist, mentor, and leader in multiple fields. He constantly reminded us that over-promising would backfire. Rest in peace, Andrew.
Delighted to join #MetabolicEngineering as Associate Editor w/Sang Yup Lee, Jay Keasling, I. Borodina, C. Maranas & C. Wittmann. I'll handle submissions in #SyntheticMetabolism, #Pseudomonas, #SynBio, new-to-nature #bioproduction & #EnvironmentalBiotechnology!
September 2, 2025 at 4:50 PM
Delighted to join #MetabolicEngineering as Associate Editor w/Sang Yup Lee, Jay Keasling, I. Borodina, C. Maranas & C. Wittmann. I'll handle submissions in #SyntheticMetabolism, #Pseudomonas, #SynBio, new-to-nature #bioproduction & #EnvironmentalBiotechnology!
Saying goodbye to Elio Schaechter, a titan of the #Microbiology field. Farewell Elio!
August 21, 2025 at 5:29 PM
Saying goodbye to Elio Schaechter, a titan of the #Microbiology field. Farewell Elio!
#Synthetic C1 #metabolism in #Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway—led by J. Turlin, M. G. Alván, @oscarpuiggene.bsky.social w/@stefanodonati.bsky.social & @sebwenk.bsky.social @mbio.bsky.social #SynBio
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Synthetic C1 metabolism in Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway | mBio
Soluble C1 feedstocks, such as formate and methanol, have gained attention as sustainable substrates for biotechnology, with the potential to reduce greenhouse gas emissions and reliance on sugar-based resources. Despite their promise, the metabolic ...
journals.asm.org
August 21, 2025 at 3:45 PM
#Synthetic C1 #metabolism in #Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway—led by J. Turlin, M. G. Alván, @oscarpuiggene.bsky.social w/@stefanodonati.bsky.social & @sebwenk.bsky.social @mbio.bsky.social #SynBio
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Reposted by Pablo Ivan Nikel
🔍Problems with synthetic C1 metabolism? The @pabnik.bsky.social group identifies seven major barriers limiting its deployment in microorganisms and proposes specific strategies to overcome each of them. Check out their paper 👉https://doi.org/10.1093/femsre/fuaf011
July 16, 2025 at 11:03 AM
🔍Problems with synthetic C1 metabolism? The @pabnik.bsky.social group identifies seven major barriers limiting its deployment in microorganisms and proposes specific strategies to overcome each of them. Check out their paper 👉https://doi.org/10.1093/femsre/fuaf011
Reposted by Pablo Ivan Nikel
📍 Milan | TODAY!
Join Amedea Perfumo & @pabnik.bsky.social at #FEMS 2025 for a dynamic session🧬 "Something (very) old, something new: Innovative microbial solutions for sustainability challenges
🕦 15 July | 11:30–13:00 | Tower Lounge
🔗 femsmicro.org
▶️ youtu.be/0-bhcMpjJ_c
#TolerateEUProject
Join Amedea Perfumo & @pabnik.bsky.social at #FEMS 2025 for a dynamic session🧬 "Something (very) old, something new: Innovative microbial solutions for sustainability challenges
🕦 15 July | 11:30–13:00 | Tower Lounge
🔗 femsmicro.org
▶️ youtu.be/0-bhcMpjJ_c
#TolerateEUProject
July 15, 2025 at 5:51 AM
📍 Milan | TODAY!
Join Amedea Perfumo & @pabnik.bsky.social at #FEMS 2025 for a dynamic session🧬 "Something (very) old, something new: Innovative microbial solutions for sustainability challenges
🕦 15 July | 11:30–13:00 | Tower Lounge
🔗 femsmicro.org
▶️ youtu.be/0-bhcMpjJ_c
#TolerateEUProject
Join Amedea Perfumo & @pabnik.bsky.social at #FEMS 2025 for a dynamic session🧬 "Something (very) old, something new: Innovative microbial solutions for sustainability challenges
🕦 15 July | 11:30–13:00 | Tower Lounge
🔗 femsmicro.org
▶️ youtu.be/0-bhcMpjJ_c
#TolerateEUProject
Reposted by Pablo Ivan Nikel
Check out our newest article led by @oscarpuiggene.bsky.social !
Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug w/carbon conservation, led by ÒscarPuiggené @labnikel.bsky.social · #SynBio #MetabolicEngineering #Methanol published in @cp-trendsbiotech.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Systematic engineering of synthetic serine cycles in Pseudomonas putida uncovers emergent topologies for methanol assimilation
The urgent need for a circular carbon economy has driven research into sustainable substrates, including one-carbon (C1) compounds. The non-pathogenic…
www.sciencedirect.com
July 9, 2025 at 11:15 AM
Check out our newest article led by @oscarpuiggene.bsky.social !
Reposted by Pablo Ivan Nikel
The 5th edition of the #Pseudomonas grass roots meeting will take place on the 27th/28th of October 2025 in Denmark. This year, our group at DTU Biosustain will host 2 exciting days of networking, exchanging ideas and learning for early career-stage scientists working with Pseudomonas. 👇
July 9, 2025 at 11:21 AM
The 5th edition of the #Pseudomonas grass roots meeting will take place on the 27th/28th of October 2025 in Denmark. This year, our group at DTU Biosustain will host 2 exciting days of networking, exchanging ideas and learning for early career-stage scientists working with Pseudomonas. 👇
Reposted by Pablo Ivan Nikel
🧬 The language of SEVA expands! The group of @pabnik.bsky.social use #SEVAplasmids nomenclature in the design of CIFR—a novel iterative transposon tool for genomic engineering of Gam-negative bacteria. 👉 doi.org/10.1016/j.ym...
Redirecting
doi.org
July 9, 2025 at 11:02 AM
🧬 The language of SEVA expands! The group of @pabnik.bsky.social use #SEVAplasmids nomenclature in the design of CIFR—a novel iterative transposon tool for genomic engineering of Gam-negative bacteria. 👉 doi.org/10.1016/j.ym...
🚨 Due to popular demand, the deadline to apply for the @cshlnews.bsky.social course Advanced #SynBio & #Metabolic #Engineering of #Pseudomonas is extended to July 22! #PhD students & #postdocs welcome!
📍Suzhou, China
📅 Sept 7–21
🔗Apply now: csh-asia.org?content/2642
📍Suzhou, China
📅 Sept 7–21
🔗Apply now: csh-asia.org?content/2642
July 9, 2025 at 9:44 AM
🚨 Due to popular demand, the deadline to apply for the @cshlnews.bsky.social course Advanced #SynBio & #Metabolic #Engineering of #Pseudomonas is extended to July 22! #PhD students & #postdocs welcome!
📍Suzhou, China
📅 Sept 7–21
🔗Apply now: csh-asia.org?content/2642
📍Suzhou, China
📅 Sept 7–21
🔗Apply now: csh-asia.org?content/2642
Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug w/carbon conservation, led by ÒscarPuiggené @labnikel.bsky.social · #SynBio #MetabolicEngineering #Methanol published in @cp-trendsbiotech.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Systematic engineering of synthetic serine cycles in Pseudomonas putida uncovers emergent topologies for methanol assimilation
The urgent need for a circular carbon economy has driven research into sustainable substrates, including one-carbon (C1) compounds. The non-pathogenic…
www.sciencedirect.com
July 7, 2025 at 4:09 PM
Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug w/carbon conservation, led by ÒscarPuiggené @labnikel.bsky.social · #SynBio #MetabolicEngineering #Methanol published in @cp-trendsbiotech.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Pablo Ivan Nikel
Today, the #TOLERATEProject held its 1st Review Meeting (M1–M18) with PO & PM highlighting our progress, innovation & first results. A key step to shape the road ahead! 🔬🌱💦
Learn more: https://tolerate-eu-project.com/
#HorizonEurope #EUProjects #Biotechnology #SustainableAgriculture
Learn more: https://tolerate-eu-project.com/
#HorizonEurope #EUProjects #Biotechnology #SustainableAgriculture
June 30, 2025 at 1:02 PM
Today, the #TOLERATEProject held its 1st Review Meeting (M1–M18) with PO & PM highlighting our progress, innovation & first results. A key step to shape the road ahead! 🔬🌱💦
Learn more: https://tolerate-eu-project.com/
#HorizonEurope #EUProjects #Biotechnology #SustainableAgriculture
Learn more: https://tolerate-eu-project.com/
#HorizonEurope #EUProjects #Biotechnology #SustainableAgriculture