Andreas P.M. Weber 🌾🌱🧬
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apmweber.bsky.social
Andreas P.M. Weber 🌾🌱🧬
@apmweber.bsky.social
Plant scientist. Keen on understanding the inner works of photosynthesis. Works at @hhu.bsky.social

https://www.plant-biochemistry.hhu.de
Last PhD of the year. Congratulations Vanessa to an excellent PhD! @weberlab.bsky.social @hhu.de
December 16, 2025 at 12:19 PM
📣Interested in doing your PhD in Plant Sciences 🌱, Microbial Sciences 🦠 or Computational Biology 👩‍💻? @ceplas.bsky.social offers 10 fully funded PhD 🎓fellowships. Pls repost and forward to interested candidates holding BSc degree.
December 11, 2025 at 8:34 AM
Reposted by Andreas P.M. Weber 🌾🌱🧬
🚀 Big news in genome annotation! The latest Nature Methods paper presents Helixer. Developed as part of the @denbi.bsky.social infrastructure, Helixer makes high-quality genome annotations more accessible and efficient for the community.
🔗 nature.com/articles/s41592-025-02939-1
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
www.nature.com
December 8, 2025 at 8:45 AM
Formate dehydrogenase is targeted to mitochondria (not chloroplasts) and constitutes a C1 shunt between mitochondria and cytoplasm

Mitochondrial formate dehydrogenase links mitochondrial and cytosolic one carbon metabolism via a one-carbon shunt url: academic.oup.com/plphys/artic...
December 6, 2025 at 2:19 PM
Cleomaceae are the sister group to the Brassicaceae. In contrast to the Brassicaceae, they contain true C4 photosynthetic species. This indicates that the genetic capacity to evolve C4 is ancestral to the split of Brassicaceae and Cleomaceae.

onlinelibrary.wiley.com/doi/10.1111/...
Cleomaceae: diversity and potential of a model family for studies on the evolution of photosynthesis
The Cleomaceae family integrates floral diversity, physiological plasticity, and the evolution of C4 photosynthesis, serving as an important model to investigate plant adaptation and evolutionary inn...
onlinelibrary.wiley.com
December 6, 2025 at 1:58 PM
Reposted by Andreas P.M. Weber 🌾🌱🧬
“Make America Healthy Again” will make the world sicker: The public health policies of the US administration will have dire results for national and global health: EMBO reports: Vol 0, No 0 www.embopress.org/doi/full/10.... #MAHA #RFKJr
www.embopress.org
November 18, 2025 at 10:25 PM
Reposted by Andreas P.M. Weber 🌾🌱🧬
Ganz unabhängig davon, wie man zu den Neuen Genomischen Techniken (NGTs) steht, gibt es natürlich einfach grundlegende Fakten, die man nicht einfach ingnorieren kann.
Leider stellt Frau Krenkel in dem Interview einige Falschbehauptungen auf:
1/
December 1, 2025 at 4:17 PM
Reposted by Andreas P.M. Weber 🌾🌱🧬
"Plant single cell RNAseq workshop: From current technologies to data analyses"  Saclay Plant Sciences Summer School, June 28 - July 3, 2026 – Versailles (France)
"Plant single cell RNAseq workshop: From current technologies to data analyses"  Saclay Plant Sciences Summer School, June 28 - July 3, 2026 – Versailles (France)
This Summer school is organized by the Saclay Plant Sciences (SPS) network, one of the largest European plant sciences communities.   scRNAseq approaches have revolutionized the way biologists approach their research subjects, by making it possible to dissect molecular mechanisms at the single-cell level. But although technological developments have recently made these approaches more accessible, their expensive use still requires significant technical training, including the good conception of experimental designs, the preparation of samples as well as their bioinformatics analyses. In addition, different protocols and various bioinformatics and statistical analyzes are available, and it can be difficult to choose the most relevant ones for the biological question at hand.   Over five days, the SPS Summer School 2026 will cover all the stages of a scRNAseq project in plants. Through a combination of lectures and practical work, the many specific features of plant models will be highlighted by experts from the Saclay Plant Sciences network (CNRS and INRAE), the ViB in Ghent and the Pasteur Institute. After this international school, participants will: –    Have an overview of the different scRNAseq technologies and understand their pros and cons. –    Be able to design experiments depending on the biological question.  –    Be trained on sample preparation techniques for single cell and single nuclei –    Understand the different steps of bioinformatics and statistical analysis –    Have a better biological interpretation of results –    Have facilitated exchanges with technology platforms, bioinformaticians, and biostatisticians in order to successfully complete their scRNAseq project The summer school will bring together outstanding and enthusiastic young scientists (PhD students and post-docs) from all over the world in order to exchange knowledge and ideas. It is limited to a small group of participants (20 maximum) to privilege informal interactions and scientific discussions   Application deadline: March 12, 2026 (midnight) Answers will be sent mid-April at the latest.    
eng-saclay-plant-sciences.hub.inrae.fr
November 26, 2025 at 7:53 PM
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.

No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.

Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com

www.nature.com/articles/s41...
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
www.nature.com
November 26, 2025 at 6:00 AM
Reposted by Andreas P.M. Weber 🌾🌱🧬
📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!
Postdoc (m/f/d) in Endosymbiosis Research
karriere.hhu.de
November 25, 2025 at 11:21 AM
Reposted by Andreas P.M. Weber 🌾🌱🧬
Hustle 🌱 👩‍🔬👨‍🔬🔬guys! Last day to register for #MBP2026 by @plantsciencedbg.bsky.social at: www.pflanzen-molekularbiologie.de/en/conferenc...
Registration
Registration: Conference of Molecular Biology of Plants
www.pflanzen-molekularbiologie.de
November 23, 2025 at 9:52 AM
Reposted by Andreas P.M. Weber 🌾🌱🧬
Tomorrow Luciana Gaccione from Lorenzo Barchi's lab will explain on our @nanoporetech.com day at HHU Düsseldorf, how to turn what we sequenced with 9.41 technology (!) into a high quality pangenome. If you can't make it, read all about it here as well: www.nature.com/articles/s41...
Graph-based pangenomes and pan-phenome provide a cornerstone for eggplant biology and breeding - Nature Communications
Eggplants are important vegetables worldwide. Here, the authors report 40 genome assemblies of Solanum melongena, its progenitor S. insanum and the allied species S. incanum to construct two pangenome...
www.nature.com
November 18, 2025 at 11:23 AM
Reposted by Andreas P.M. Weber 🌾🌱🧬
A small contribution from us & Edi Gerhardt @febsj.bsky.social

Highlighting the recent findings: Structure of the NifL-NifA complex controlling nitrogen fixation gene expression in Azotobacter

febs.onlinelibrary.wiley.com/doi/10.1111/...
@sfb1381.bsky.social @hhu.de @mibinet.bsky.social
FEBS Press
The urgent need for sustainable agriculture places biological nitrogen fixation at the forefront of current biotechnological research. Plant growth-promoting rhizobacteria play crucial roles in agric...
febs.onlinelibrary.wiley.com
November 17, 2025 at 4:55 PM
Reposted by Andreas P.M. Weber 🌾🌱🧬
Countdown: there are only 9 days left ... if you want to join

Molecular Biology of Plants (#MBP2026) Conference in Hennef

Registration + abstract submission end on
🗓️ 23rd November 2025

www.pflanzen-molekularbiologie.de/en/conferenc...
Registration is open to take part in the Molecular Biology of Plants (#MBP2026), which especially invites early career scientists to present their molecular #plantsci research www.pflanzen-molekularbiologie.de/en/conferenc...
November 14, 2025 at 11:01 AM
Strong BSC enrichment of GLDP, GLDT, SHM, GGT, GOX, and GS2/GOGAT — the full photorespiratory glycine–serine–NH₃ cycle is shifted from mesophyll to BSC in C3-C4 Moricandia arvensis
This shift couples CO₂ concentration, nitrogen re-assimilation, and redox balance within BSC mitochondria and plastids.
🌿 RESEARCH 🌿

Single-nucleus RNAseq reveals bundle sheath cell-specific photorespiration pathways in Moricandia arvensis, incl ammonium assimilation & redox regulation, highlighting metabolic compartmentalization in C3–C4 photosynthesis – Triesch et al.

🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
November 11, 2025 at 2:23 PM
🌱 The #TaCoCass Team in the field: evaluating #cassava lines with diverse architecture and productivity. The trials highlight the genetic variation that underpins efforts to boost photosynthetic efficiency in cassava, paving the way toward more resilience and higher yield
#Cassava #Photosynthesis
September 30, 2025 at 4:22 PM
Reposted by Andreas P.M. Weber 🌾🌱🧬
New Insights Into Bacterial Motility and DNA Transfer:
a small press on our discovery of ComFB signaling family by @claussenarne.bsky.social @hhu.de

www.eurekalert.org/news-release...
w/ @mygalperin.bsky.social @thethormannden.bsky.social
@cmfi.bsky.social @mibinet.bsky.social @sfb1381.bsky.social
September 29, 2025 at 11:20 AM
A new crop in the lab. 🌱 Field day with TaCoCass team members — working to boost photosynthetic efficiency in cassava and secure a more sustainable food future. #Cassava #Photosynthesis #FoodSecurity
September 29, 2025 at 7:00 AM
We are deeply saddened by the news that Andrew D. Hanson (@adhansonlab.bsky.social) is no longer with us. He was an exceptional scientist, mentor, and leader in multiple fields. He constantly reminded us that over-promising would backfire. Rest in peace, Andrew.
September 3, 2025 at 5:00 AM
RETICULATA1 (RE1) exports basic amino acids from plastids—implications for amino-acid homeostasis and development.
News & Views: “Reticulata Weaves the Metabolic Net” (Katrin Philippar, Nature Plants). doi.org/10.1038/s414... @natplants.nature.com #PlantScience #Arabidopsis
August 27, 2025 at 6:16 AM
Coming out in @NaturePlants today (rdcu.be/eBScJ): The mechanism for essential amino acid transport across the chloroplast envelope. We identified RETICULATA1 (RE1) as a new type of transport protein. #PlantScience #AminoAcidTransport #Chloroplasts. @franzikuhnert.bsky.social @weberlab.bsky.social
August 22, 2025 at 12:03 PM
Reposted by Andreas P.M. Weber 🌾🌱🧬
Last month, our consortium met in Tartu, Estonia, to share our latest progress and reflect on what’s next for our #H2020 project. Here is a sneak peek! 📽️ 🌻

There were lots of updates, including cross-consortium publications, regulatory deliverables, and upcoming trials.
July 22, 2025 at 1:04 PM
GDC, but also SHM, GGAT, and GOX are predominantly bundle-sheath expressed in C3-C4 intermediate Moricandia

Single-nuclei sequencing of Moricandia arvensis reveals bundle sheath cell function in the photorespiratory shuttle of C3-C4 intermediate Brassicaceae url: academic.oup.com/jxb/article/...
Single-nuclei sequencing of Moricandia arvensis reveals bundle sheath cell function in the photorespiratory shuttle of C3-C4 intermediate Brassicaceae
Abstract. Spatially confined gene expression determines cell identity and is fundamental to complex plant traits. In the evolutionary transition from C3 to
academic.oup.com
July 1, 2025 at 12:49 PM