Microbial Biotechnology (MBT)
@microbiotech.bsky.social
Official account of Microbial Biotechnology journal. Original research reporting significant advances in any aspect of microbial applications.
John-wiley & Sons Ltd
https://enviromicro-journals.onlinelibrary.wiley.com/journal/17517915
John-wiley & Sons Ltd
https://enviromicro-journals.onlinelibrary.wiley.com/journal/17517915
Pinned
#MicroSky: MBT has received a score of 9.9 in the latest Cite Score rankings! We are thrilled to be in the top 12% of Applied Microbiology and Biotechnology journals. THANKS to our incredible readers, contributors, staff members, and editors for their unwavering support!!!
#MicroSky: Directed evolution rewired AlkS to sense isobutanol with high specificity. Fine-tuning via mutagenesis and promoter engineering boosted the biosensor sensitivity 114%. A strong platform for high-throughput screening of alcohol-producing strains. Read Chen et al doi.org/10.1111/1751...
February 13, 2026 at 11:02 AM
#MicroSky: Directed evolution rewired AlkS to sense isobutanol with high specificity. Fine-tuning via mutagenesis and promoter engineering boosted the biosensor sensitivity 114%. A strong platform for high-throughput screening of alcohol-producing strains. Read Chen et al doi.org/10.1111/1751...
#MicroSky: ONE HEALTH: Betulinic acid combats Staphylococcus aureus biofilms on implants by blocking adhesion and EPS/eDNA formation, boosting immune clearance. It reduces inflammation, enhances type I collagen & accelerates wound healing. Read in MBT at doi.org/10.1111/1751...
February 12, 2026 at 11:01 AM
#MicroSky: ONE HEALTH: Betulinic acid combats Staphylococcus aureus biofilms on implants by blocking adhesion and EPS/eDNA formation, boosting immune clearance. It reduces inflammation, enhances type I collagen & accelerates wound healing. Read in MBT at doi.org/10.1111/1751...
#MicroSky: CIRCULAR ECONOMY: Thermal cycling & fungal inoculants (Fomes lignosus & Penicillium glabrum) reshape compost microbiomes, boosting humification with 5% increase in carbon conversion & humic acid yield. A smart path for lignocellulosic waste valorization! Read doi.org/10.1111/1751...
February 11, 2026 at 11:00 AM
#MicroSky: CIRCULAR ECONOMY: Thermal cycling & fungal inoculants (Fomes lignosus & Penicillium glabrum) reshape compost microbiomes, boosting humification with 5% increase in carbon conversion & humic acid yield. A smart path for lignocellulosic waste valorization! Read doi.org/10.1111/1751...
#MicroSky: PHAGES & BIOTECH. Bao et al show that previously overlooked phages drive microbial life-history trade-offs, shape organic matter transformation, and enhance soil carbon stability in agricultural ecosystems. Read Microb Biotechnol. doi.org/10.1111/1751...
February 10, 2026 at 11:00 AM
#MicroSky: PHAGES & BIOTECH. Bao et al show that previously overlooked phages drive microbial life-history trade-offs, shape organic matter transformation, and enhance soil carbon stability in agricultural ecosystems. Read Microb Biotechnol. doi.org/10.1111/1751...
#MicroSky: Extremophiles: Unlocking genetics in Halomonas. A highly efficient electroporation protocol for Halomonas elongata boosts transformation success and works across strains. A new door to genetic studies in underexplored species. Read Coimbra et al: doi.org/10.1111/1751...
February 9, 2026 at 11:01 AM
#MicroSky: Extremophiles: Unlocking genetics in Halomonas. A highly efficient electroporation protocol for Halomonas elongata boosts transformation success and works across strains. A new door to genetic studies in underexplored species. Read Coimbra et al: doi.org/10.1111/1751...
#MicroSky: ENVIRON BIOTECH: Vidal et al discuss that deep beneath Earth’s surface, life thrives in extremes. Subsurface microbiology reveals the limits and origins of life, and guides the search for biosignatures on Mars, icy moons, and distant exoplanets. Do not miss doi.org/10.1111/1751...
February 6, 2026 at 11:02 AM
#MicroSky: ENVIRON BIOTECH: Vidal et al discuss that deep beneath Earth’s surface, life thrives in extremes. Subsurface microbiology reveals the limits and origins of life, and guides the search for biosignatures on Mars, icy moons, and distant exoplanets. Do not miss doi.org/10.1111/1751...
#MicroSky: ENVIRON BIOTECH: Selenium detox meets green nanotech. Stenotrophomonas converts toxic Se oxyanions into antimicrobial selenium nanoparticles with strain-specific killing mechanisms. Biogenic SeNPs are eco-friendly, broad-spectrum antimicrobials. doi.org/10.1111/1751...
February 5, 2026 at 11:00 AM
#MicroSky: ENVIRON BIOTECH: Selenium detox meets green nanotech. Stenotrophomonas converts toxic Se oxyanions into antimicrobial selenium nanoparticles with strain-specific killing mechanisms. Biogenic SeNPs are eco-friendly, broad-spectrum antimicrobials. doi.org/10.1111/1751...
#MicroSky: FERMENTATION: Acetic acid buildup can spoil fermentations—but real-time detection is hard. A whole-cell bacterial biosensor enables low-cost, sensitive, headspace AC monitoring supporting early intervention & better quality control. The future ahead by Kesler et al doi.org/10.1111/1751...
February 4, 2026 at 11:00 AM
#MicroSky: FERMENTATION: Acetic acid buildup can spoil fermentations—but real-time detection is hard. A whole-cell bacterial biosensor enables low-cost, sensitive, headspace AC monitoring supporting early intervention & better quality control. The future ahead by Kesler et al doi.org/10.1111/1751...
#MicroSky: BIOTECH-ENVIRONMENT: Rising CO₂ demands smarter biomanufacturing. A gas-linked co-culture pairing heterotrophs with autotrophs recycles emitted CO₂, nearly doubles PHB & carotenoid output, and cuts net CO₂ by >20%. Learn about novel circular carbon biorefineries. doi.org/10.1111/1751...
February 3, 2026 at 11:00 AM
#MicroSky: BIOTECH-ENVIRONMENT: Rising CO₂ demands smarter biomanufacturing. A gas-linked co-culture pairing heterotrophs with autotrophs recycles emitted CO₂, nearly doubles PHB & carotenoid output, and cuts net CO₂ by >20%. Learn about novel circular carbon biorefineries. doi.org/10.1111/1751...
#MicroSky: ONE HEALTH: Type 2 diabetes is linked to the gut microbiota: Probiotics, prebiotics, synbiotics & fecal microbiota transplantation show promise in restoring microbial balance and improving metabolic health. Learn about new avenues for prevention and therapy. doi.org/10.1111/1751...
February 2, 2026 at 11:00 AM
#MicroSky: ONE HEALTH: Type 2 diabetes is linked to the gut microbiota: Probiotics, prebiotics, synbiotics & fecal microbiota transplantation show promise in restoring microbial balance and improving metabolic health. Learn about new avenues for prevention and therapy. doi.org/10.1111/1751...
#MicroSky: Microbial Literacy: In a world of cascading, human-made crises & information overload, better decisions are urgent. Critical thinking, taught early & practiced widely, is our best defense against bias, misinformation, and self-harm to society and planet. doi.org/10.1111/1751...
January 30, 2026 at 11:01 AM
#MicroSky: Microbial Literacy: In a world of cascading, human-made crises & information overload, better decisions are urgent. Critical thinking, taught early & practiced widely, is our best defense against bias, misinformation, and self-harm to society and planet. doi.org/10.1111/1751...
#MicroSky: Plasmid vectors still underpin molecular biology, but convenience shouldn’t trump design. De Lorenzo & Martínez revisit copy number, selection & stability, and explores modular AI-assisted vector design for robust synthetic biology across the microbial world. doi.org/10.1111/1751...
January 29, 2026 at 11:00 AM
#MicroSky: Plasmid vectors still underpin molecular biology, but convenience shouldn’t trump design. De Lorenzo & Martínez revisit copy number, selection & stability, and explores modular AI-assisted vector design for robust synthetic biology across the microbial world. doi.org/10.1111/1751...
#MicroSky: ONE HEALTH: Choudhury et al engineered Lactococcus lactis to deliver antimicrobial peptides that selectively target Fusobacterium nucleatum, a key driver of colorectal cancer, reducing biofilms & preserving gut microbiome diversity. doi.org/10.1111/1751...
January 28, 2026 at 11:00 AM
#MicroSky: ONE HEALTH: Choudhury et al engineered Lactococcus lactis to deliver antimicrobial peptides that selectively target Fusobacterium nucleatum, a key driver of colorectal cancer, reducing biofilms & preserving gut microbiome diversity. doi.org/10.1111/1751...
#MicroSky: Microbial consortia outperform single strains, but testing combinations is a bottleneck. They show that the BSocial tool predicts “social consortia” and efficiently selects stable, high-performing plant growth–promoting communities. Advancing biofertilizer design! doi.org/10.1111/1751...
January 27, 2026 at 11:01 AM
#MicroSky: Microbial consortia outperform single strains, but testing combinations is a bottleneck. They show that the BSocial tool predicts “social consortia” and efficiently selects stable, high-performing plant growth–promoting communities. Advancing biofertilizer design! doi.org/10.1111/1751...
#MicroSky: BE SOCIAL: Science Fun Day outreach for primary pupils in Essex boosted enjoyment of science, interest in science careers, and understanding of why microbes matter, showing how hands-on engagement can inspire future scientists. Don’t miss Archer et al. doi.org/10.1111/1751...
January 26, 2026 at 11:00 AM
#MicroSky: BE SOCIAL: Science Fun Day outreach for primary pupils in Essex boosted enjoyment of science, interest in science careers, and understanding of why microbes matter, showing how hands-on engagement can inspire future scientists. Don’t miss Archer et al. doi.org/10.1111/1751...
#MicroSky: Olanzapine is linked to fatty liver disease. Wang et al found altered gut microbiota, i.e. Akkermansia muciniphila, n affected patients. Supplementing A. muciniphila reduced liver injury in rats via the gut/liver axis, suggesting a new microbiota-based therapy. doi.org/10.1111/1751...
January 23, 2026 at 11:00 AM
#MicroSky: Olanzapine is linked to fatty liver disease. Wang et al found altered gut microbiota, i.e. Akkermansia muciniphila, n affected patients. Supplementing A. muciniphila reduced liver injury in rats via the gut/liver axis, suggesting a new microbiota-based therapy. doi.org/10.1111/1751...
#MicroSky: In times of climate disruption and social unrest, education must go beyond facts. Imagination, undervalued in “hard” sciences, is essential. Microbiology shows how imagining invisible worlds can foster responsibility, citizenship, and regenerative futures. doi.org/10.1111/1751...
January 22, 2026 at 11:01 AM
#MicroSky: In times of climate disruption and social unrest, education must go beyond facts. Imagination, undervalued in “hard” sciences, is essential. Microbiology shows how imagining invisible worlds can foster responsibility, citizenship, and regenerative futures. doi.org/10.1111/1751...
#MicroSky: Pichia pastoris proves its power as a sustainable, high-yield platform for recombinant proteins: methanol levels allow tuning N/O-glycosylation. Optimizing induction boosts yield, controls glycan complexity, & streamlines large-scale bioprocessing. Read Ohara et al doi.org/10.1111/1751...
January 21, 2026 at 11:00 AM
#MicroSky: Pichia pastoris proves its power as a sustainable, high-yield platform for recombinant proteins: methanol levels allow tuning N/O-glycosylation. Optimizing induction boosts yield, controls glycan complexity, & streamlines large-scale bioprocessing. Read Ohara et al doi.org/10.1111/1751...
#MicroSky: ANTIBIOTIC RESISTANCE: Multi-halogenated indoles kill drug-resistant S. aureus, disrupt biofilms, induce ROS, wipe out persisters, block resistance, inhibit quorum sensing/haemolysis, and synergize with aminoglycosides. Read Sim et al in MBT. doi.org/10.1111/1751...
January 20, 2026 at 11:00 AM
#MicroSky: ANTIBIOTIC RESISTANCE: Multi-halogenated indoles kill drug-resistant S. aureus, disrupt biofilms, induce ROS, wipe out persisters, block resistance, inhibit quorum sensing/haemolysis, and synergize with aminoglycosides. Read Sim et al in MBT. doi.org/10.1111/1751...
#MicroSky: Fermentation: Lentilactobacillus emerges as a strong malolactic starter, outperforming O. oeni at low temperatures and improving reliability, spoilage resistance, and starter diversity in cool-climate wines. Find more in Mantegazza et al. doi.org/10.1111/1751...
January 19, 2026 at 11:00 AM
#MicroSky: Fermentation: Lentilactobacillus emerges as a strong malolactic starter, outperforming O. oeni at low temperatures and improving reliability, spoilage resistance, and starter diversity in cool-climate wines. Find more in Mantegazza et al. doi.org/10.1111/1751...
Reposted by Microbial Biotechnology (MBT)
a great review!
#MicroSky: Hot in MBT 2025: Key gaps limit microbiome–gut–brain therapies, from unclear probiotic mechanisms to poor translation from animals to humans. Slykerman review maps successes, failures & how mechanistic & in silico insights can guide smarter psychobiotic advances. doi.org/10.1111/1751...
January 9, 2026 at 1:31 PM
a great review!
Reposted by Microbial Biotechnology (MBT)
Phylogeny- Aware Metabologenomics Accurately Assigns
Natural Products to Biosynthetic Gene Clusters
@microbiotech.bsky.social by Judith Boldt et al from Ulrich Nübel and @drrolfmueller.bsky.social
enviromicro-journals.onlinelibrary.wiley.com/doi/pdf/10.1...
Natural Products to Biosynthetic Gene Clusters
@microbiotech.bsky.social by Judith Boldt et al from Ulrich Nübel and @drrolfmueller.bsky.social
enviromicro-journals.onlinelibrary.wiley.com/doi/pdf/10.1...
Phylogeny‐Aware Metabologenomics Accurately Assigns Natural Products to Biosynthetic Gene Clusters
We report a statistical approach for associating biosynthetic gene clusters with their cognate metabolites and demonstrate its unprecedented power for scalable natural product discovery. Notably, it ...
enviromicro-journals.onlinelibrary.wiley.com
January 18, 2026 at 1:24 PM
Phylogeny- Aware Metabologenomics Accurately Assigns
Natural Products to Biosynthetic Gene Clusters
@microbiotech.bsky.social by Judith Boldt et al from Ulrich Nübel and @drrolfmueller.bsky.social
enviromicro-journals.onlinelibrary.wiley.com/doi/pdf/10.1...
Natural Products to Biosynthetic Gene Clusters
@microbiotech.bsky.social by Judith Boldt et al from Ulrich Nübel and @drrolfmueller.bsky.social
enviromicro-journals.onlinelibrary.wiley.com/doi/pdf/10.1...
#MicroSky: BIOGAS: Metagenomes from anaerobic digesters uncovered a new bacterial order, Candidatus Darwinibacteriales, a key syntrophic acetate oxidizer partnering with methanogens. A major step toward illuminating an uncultured but abundant player in biogas production. doi.org/10.1111/1751...
January 16, 2026 at 11:01 AM
#MicroSky: BIOGAS: Metagenomes from anaerobic digesters uncovered a new bacterial order, Candidatus Darwinibacteriales, a key syntrophic acetate oxidizer partnering with methanogens. A major step toward illuminating an uncultured but abundant player in biogas production. doi.org/10.1111/1751...
#MicroSky: Using multi-omics on 63 actinomycetes, Abdelrahman et al pinpointed 75 metabolites linked to blocking Phytophthora infestans, showing how comparing closely related strains can reveal key anti–late-blight compounds. Read: doi.org/10.1111/1751...
January 15, 2026 at 11:00 AM
#MicroSky: Using multi-omics on 63 actinomycetes, Abdelrahman et al pinpointed 75 metabolites linked to blocking Phytophthora infestans, showing how comparing closely related strains can reveal key anti–late-blight compounds. Read: doi.org/10.1111/1751...
#MicroSky: Hot in MBT 2025: A new genome-editing toolkit and improved chassis for Caldimonas thermodepolymerans accelerate its development as a thermophilic producer of biodegradable plastics. Read Grybcuk-Ieremenko et al in MBT. doi.org/10.1111/1751...
January 14, 2026 at 11:01 AM
#MicroSky: Hot in MBT 2025: A new genome-editing toolkit and improved chassis for Caldimonas thermodepolymerans accelerate its development as a thermophilic producer of biodegradable plastics. Read Grybcuk-Ieremenko et al in MBT. doi.org/10.1111/1751...