@sevaplasmids.bsky.social
A non-profit Open Access repository of standardised plasmids following the SEVA format. Check out our database and request your #plasmid free of charge #synbio
seva-plasmids.com
seva-plasmids.com
A standardised plasmid repository for experimental replicability ⭕. Check #SEVAplasmids database and join the movement!
👉 seva-plasmids.com/find-your-pl...
👉 seva-plasmids.com/find-your-pl...
January 7, 2026 at 1:02 PM
A standardised plasmid repository for experimental replicability ⭕. Check #SEVAplasmids database and join the movement!
👉 seva-plasmids.com/find-your-pl...
👉 seva-plasmids.com/find-your-pl...
✨And with that the 2025 season comes to an end...
But at SEVA we continue working for a replicable and reliable science🤝 We want to thank you all for your support through this past year, and we can’t wait for all the surprises 2026 will bring! 🤩
But at SEVA we continue working for a replicable and reliable science🤝 We want to thank you all for your support through this past year, and we can’t wait for all the surprises 2026 will bring! 🤩
December 31, 2025 at 11:00 AM
✨And with that the 2025 season comes to an end...
But at SEVA we continue working for a replicable and reliable science🤝 We want to thank you all for your support through this past year, and we can’t wait for all the surprises 2026 will bring! 🤩
But at SEVA we continue working for a replicable and reliable science🤝 We want to thank you all for your support through this past year, and we can’t wait for all the surprises 2026 will bring! 🤩
📋Your plasmid and your plasmid documentation all in one place! Have a look at the possibility of plasmids with self-encoded documentation files 👉 doi.org/10.1016/j.ti...
Self-documenting plasmids
Plasmids are the workhorse of biotechnology. These small DNA molecules are used to produce recombinant proteins and to engineer living organisms. They…
doi.org
December 29, 2025 at 11:00 AM
📋Your plasmid and your plasmid documentation all in one place! Have a look at the possibility of plasmids with self-encoded documentation files 👉 doi.org/10.1016/j.ti...
👩🔬Can’t find your plasmid? We’ve got you covered! Design your own vector looking for the different pieces to assemble it yourself. All for free 👉 seva-plasmids.com
Home - SEVA plasmids - Standard European Vector Architecture
Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…
seva-plasmids.com
December 26, 2025 at 11:00 AM
👩🔬Can’t find your plasmid? We’ve got you covered! Design your own vector looking for the different pieces to assemble it yourself. All for free 👉 seva-plasmids.com
From a non-model organism to a promising industrial chassis✨. Have a look at the developments on synthetic biology tools and the engineering potential of Halomonas. SEVA plasmids have been used in some of these efforts, check the review 👉 doi.org/10.1186/s129...
Establishing Halomonas as a chassis for industrial biotechnology: advances in synthetic biology tool development and metabolic engineering strategies - Microbial Cell Factories
Background Halomonas species have recently emerged as promising chassis organisms for next-generation industrial biotechnology, due to their ability to thrive under high-salt conditions, where most…
doi.org
December 23, 2025 at 11:00 AM
From a non-model organism to a promising industrial chassis✨. Have a look at the developments on synthetic biology tools and the engineering potential of Halomonas. SEVA plasmids have been used in some of these efforts, check the review 👉 doi.org/10.1186/s129...
🤝Professional labs around the globe are expanding SEVA and its standard. Meet our collaborators and learn about their research!
seva-plasmids.com/the-seva-com...
seva-plasmids.com/the-seva-com...
COLLABORATORS & RESOURCES - SEVA plasmids - Standard European Vector Architecture
The SEVA commonwealth Laboratory of Dr. Sven Panke. Bioprocess laboratory. ETH. Switzerland. Laboratory of Dr. Nediljko Budisa.
seva-plasmids.com
December 18, 2025 at 1:30 PM
🤝Professional labs around the globe are expanding SEVA and its standard. Meet our collaborators and learn about their research!
seva-plasmids.com/the-seva-com...
seva-plasmids.com/the-seva-com...
👀 Researchers at University of Warwick explore how to maintain the expression of synthetic gene circuits over time in bacteria. They propose three genetic controllers that improve simple circuit half-life over threefold. Take a look 👉 doi.org/10.1038/s414...
Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria - Nature Communications
Engineered gene circuits often degrade over time due to mutation and selection. Here the authors use a host-aware modelling framework to develop genetic controllers to sustain synthetic gene…
doi.org
December 17, 2025 at 1:00 PM
👀 Researchers at University of Warwick explore how to maintain the expression of synthetic gene circuits over time in bacteria. They propose three genetic controllers that improve simple circuit half-life over threefold. Take a look 👉 doi.org/10.1038/s414...
A plasmid stabilization system offers a way to reduce antibiotic reliance in riboflavin bacterial production. Learn more about the solution 👇 👇
doi.org/10.1016/j.sy...
doi.org/10.1016/j.sy...
Construction of antibiotic-free riboflavin producer in Escherichia coli by metabolic engineering strategies with a plasmid stabilization system
Riboflavin, an important vitamin utilized in pharmaceutical products and as a feed additive, is mainly produced by metabolically engineered bacterial …
doi.org
December 12, 2025 at 1:00 PM
A plasmid stabilization system offers a way to reduce antibiotic reliance in riboflavin bacterial production. Learn more about the solution 👇 👇
doi.org/10.1016/j.sy...
doi.org/10.1016/j.sy...
🎄🦠You don’t know what to give your lab team for Christmas this year yet? What about a customised plasmid perfect for your research? Have a look at our #SEVAplasmids database! 👉 seva-plasmids.com/find-your-pl...
FIND YOUR PLASMID - SEVA plasmids - Standard European Vector Architecture
Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your…
seva-plasmids.com
December 8, 2025 at 11:01 AM
🎄🦠You don’t know what to give your lab team for Christmas this year yet? What about a customised plasmid perfect for your research? Have a look at our #SEVAplasmids database! 👉 seva-plasmids.com/find-your-pl...
💡A ”shred of light” on contaminants detection! A study shows promising combined biosensors for a more effective and rapid detection of toxins and contaminants. Take a look 👉https://doi.org/10.1016/j.bios.2025.117369
December 4, 2025 at 1:03 PM
💡A ”shred of light” on contaminants detection! A study shows promising combined biosensors for a more effective and rapid detection of toxins and contaminants. Take a look 👉https://doi.org/10.1016/j.bios.2025.117369
📖Have you used our #SEVAplasmids database selector? Consult our glossary for Acronyms and Antibiotics abbreviations to easily filter specific features.
👉https://seva-plasmids.com/find-your-plasmid/
👉https://seva-plasmids.com/find-your-plasmid/
FIND YOUR PLASMID - SEVA plasmids - Standard European Vector Architecture
Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your…
seva-plasmids.com
December 1, 2025 at 1:11 PM
📖Have you used our #SEVAplasmids database selector? Consult our glossary for Acronyms and Antibiotics abbreviations to easily filter specific features.
👉https://seva-plasmids.com/find-your-plasmid/
👉https://seva-plasmids.com/find-your-plasmid/
💊 SMARTS biotool for smart #SynBio!
This Streptomyces Multiplexed Artificial Control System boosts production of specific secondary metabolites in this species, which contribute to about half of drugs obtained from microorganisms! Learn more about it: doi.org/10.1038/s415...
This Streptomyces Multiplexed Artificial Control System boosts production of specific secondary metabolites in this species, which contribute to about half of drugs obtained from microorganisms! Learn more about it: doi.org/10.1038/s415...
Orchestration of secondary metabolite production in Streptomyces species - Nature Biotechnology
We developed a universal control system and multitarget optimization framework that enables dynamic and synchronized expression of multiple genes and facilitates the overproduction of specific…
doi.org
November 28, 2025 at 11:01 AM
💊 SMARTS biotool for smart #SynBio!
This Streptomyces Multiplexed Artificial Control System boosts production of specific secondary metabolites in this species, which contribute to about half of drugs obtained from microorganisms! Learn more about it: doi.org/10.1038/s415...
This Streptomyces Multiplexed Artificial Control System boosts production of specific secondary metabolites in this species, which contribute to about half of drugs obtained from microorganisms! Learn more about it: doi.org/10.1038/s415...
🧬 Looking for the perfect plasmid?
Explore our #SEVAplasmids database. Request any construct for free, or be the first to design one and share it with the community!
Join the standard 👉 seva-plasmids.com/find-your-pl...
Explore our #SEVAplasmids database. Request any construct for free, or be the first to design one and share it with the community!
Join the standard 👉 seva-plasmids.com/find-your-pl...
FIND YOUR PLASMID - SEVA plasmids - Standard European Vector Architecture
Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your…
seva-plasmids.com
November 26, 2025 at 11:01 AM
🧬 Looking for the perfect plasmid?
Explore our #SEVAplasmids database. Request any construct for free, or be the first to design one and share it with the community!
Join the standard 👉 seva-plasmids.com/find-your-pl...
Explore our #SEVAplasmids database. Request any construct for free, or be the first to design one and share it with the community!
Join the standard 👉 seva-plasmids.com/find-your-pl...
💡Glutamate from methanol?
This study confirms that MscS channels in Bacillus methanolicus are key L-glutamate exporters, suggesting a way to unlock the bacterium’s potential for sustainable methanol-based glutamate production.
Take a look 👉 doi.org/10.1111/1751...
This study confirms that MscS channels in Bacillus methanolicus are key L-glutamate exporters, suggesting a way to unlock the bacterium’s potential for sustainable methanol-based glutamate production.
Take a look 👉 doi.org/10.1111/1751...
doi.org
November 24, 2025 at 11:01 AM
💡Glutamate from methanol?
This study confirms that MscS channels in Bacillus methanolicus are key L-glutamate exporters, suggesting a way to unlock the bacterium’s potential for sustainable methanol-based glutamate production.
Take a look 👉 doi.org/10.1111/1751...
This study confirms that MscS channels in Bacillus methanolicus are key L-glutamate exporters, suggesting a way to unlock the bacterium’s potential for sustainable methanol-based glutamate production.
Take a look 👉 doi.org/10.1111/1751...
🚀 New breakthrough! Researchers from the D-CHAB and the TUM Faculty of Natural Sciences have designed bacterial ABC transporters to efficiently import non-canonical amino acids. This achievement is a significant step towards expanding the genetic code. doi.org/10.1038/s415...
Hijacking a bacterial ABC transporter for genetic code expansion - Nature
Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel…
doi.org
November 21, 2025 at 11:02 AM
🚀 New breakthrough! Researchers from the D-CHAB and the TUM Faculty of Natural Sciences have designed bacterial ABC transporters to efficiently import non-canonical amino acids. This achievement is a significant step towards expanding the genetic code. doi.org/10.1038/s415...
🚀 Take your genetic engineering to the next level!
#SEVA plasmids give you a flexible, plug-and-play platform for your #SynBio designs.
Mix, match, and build the plasmid you need, all in one place 👇
seva-plasmids.com/find-your-pl...
#SEVA plasmids give you a flexible, plug-and-play platform for your #SynBio designs.
Mix, match, and build the plasmid you need, all in one place 👇
seva-plasmids.com/find-your-pl...
FIND YOUR PLASMID - SEVA plasmids - Standard European Vector Architecture
Canonical SEVA plasmids that use Golden Gate assembly to build complex genetic circuits. Find your canonical plasmid In the dropdown menu below, you can select a combination of choice for your…
seva-plasmids.com
November 19, 2025 at 11:02 AM
🚀 Take your genetic engineering to the next level!
#SEVA plasmids give you a flexible, plug-and-play platform for your #SynBio designs.
Mix, match, and build the plasmid you need, all in one place 👇
seva-plasmids.com/find-your-pl...
#SEVA plasmids give you a flexible, plug-and-play platform for your #SynBio designs.
Mix, match, and build the plasmid you need, all in one place 👇
seva-plasmids.com/find-your-pl...
🤖 GPT goes #SynBio! Researchers at Chinese Academy of Sciences introduce SynBioGPT v2.0, an AI Large Language Model for SynBio that automates knowledge extraction and strain design. Tested on a 100-question SynBio benchmark, it achieved 98% accuracy!
Take a look: doi.org/10.1101/2025...
Take a look: doi.org/10.1101/2025...
SynBioGPT: A Retrieval-Augmented Large Language Model Platform for AI-Guided Microbial Strain Development
Synthetic biology seeks to engineer microbial cell factories for sustainable bioproduction, yet the optimization of these systems is impeded by the complexity of metabolic engineering and the…
doi.org
November 17, 2025 at 11:02 AM
🤖 GPT goes #SynBio! Researchers at Chinese Academy of Sciences introduce SynBioGPT v2.0, an AI Large Language Model for SynBio that automates knowledge extraction and strain design. Tested on a 100-question SynBio benchmark, it achieved 98% accuracy!
Take a look: doi.org/10.1101/2025...
Take a look: doi.org/10.1101/2025...
🚨 News on bioremediation! A study published in Nature reveals how by genetically modifying the bacterium Vibrio natriegens, it simultaneously degrades five toxic contaminants in industrial wastewater and saline soils. Read the full article: www.nature.com/articles/d41...
Engineered bacteria can degrade five wastewater pollutants at the same time
Five gene clusters have been introduced into a single rapidly growing bacterial strain.
www.nature.com
November 14, 2025 at 11:02 AM
🚨 News on bioremediation! A study published in Nature reveals how by genetically modifying the bacterium Vibrio natriegens, it simultaneously degrades five toxic contaminants in industrial wastewater and saline soils. Read the full article: www.nature.com/articles/d41...
👩🔬 Want to team up with us to expand the #SEVA collection?
Contribute your own constructs to our open plasmid repository and help make #SynBio more reproducible for everyone.
✨ Check out our contribution guidelines and join the mission!👇👇
seva-plasmids.com
Contribute your own constructs to our open plasmid repository and help make #SynBio more reproducible for everyone.
✨ Check out our contribution guidelines and join the mission!👇👇
seva-plasmids.com
Home - SEVA plasmids - Standard European Vector Architecture
Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…
seva-plasmids.com
November 12, 2025 at 11:01 AM
👩🔬 Want to team up with us to expand the #SEVA collection?
Contribute your own constructs to our open plasmid repository and help make #SynBio more reproducible for everyone.
✨ Check out our contribution guidelines and join the mission!👇👇
seva-plasmids.com
Contribute your own constructs to our open plasmid repository and help make #SynBio more reproducible for everyone.
✨ Check out our contribution guidelines and join the mission!👇👇
seva-plasmids.com
Designing replication sequences is challenging in #SynBio. Researchers at the Innovative Genomics Institute present OriGEN, a language model generating functional plasmids beyond wild type, capturing the complex mechanisms of biological replication.
👉 doi.org/10.1101/2025...
👉 doi.org/10.1101/2025...
Generating functional plasmid origins with OriGen
While generative artificial intelligence has shown promise for biological design, no computational system has yet created sequences proven capable of replication. Focusing on plasmids as minimal…
doi.org
November 10, 2025 at 11:02 AM
Designing replication sequences is challenging in #SynBio. Researchers at the Innovative Genomics Institute present OriGEN, a language model generating functional plasmids beyond wild type, capturing the complex mechanisms of biological replication.
👉 doi.org/10.1101/2025...
👉 doi.org/10.1101/2025...
🚀 Meet Constructive Bio! This biotech turns living bacteria into programmable biofactories creating new classes of polymers. At #SEVA, we love seeing initiatives like this driving innovation in #SynBio. Read more 👉 www.nature.com/articles/s41...
Editor’s pick: Constructive Bio - Nature Biotechnology
Each year, Nature Biotechnology highlights companies that received sizeable early-stage funding in the previous year. Constructive Bio is using synthetic E. coli and non-canonical amino acids to…
www.nature.com
November 7, 2025 at 11:01 AM
🚀 Meet Constructive Bio! This biotech turns living bacteria into programmable biofactories creating new classes of polymers. At #SEVA, we love seeing initiatives like this driving innovation in #SynBio. Read more 👉 www.nature.com/articles/s41...
💭 Imagine #SynBio research where every experiment can be easily replicated and labs collaborate seamlessly. No technical hurdles, just shared progress. That’s our vision at #SEVA! Get your free plasmids and join the movement for #standardisation 👉https://seva-plasmids.com/
Home - SEVA plasmids - Standard European Vector Architecture
Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes WHAT…
seva-plasmids.com
November 5, 2025 at 11:00 AM
💭 Imagine #SynBio research where every experiment can be easily replicated and labs collaborate seamlessly. No technical hurdles, just shared progress. That’s our vision at #SEVA! Get your free plasmids and join the movement for #standardisation 👉https://seva-plasmids.com/
Pseudomonas chlororaphis is a promising biofactory, but hard to engineer. A new piece of work has characterised its endogenous CRISPR/Cas I–F system and built a precise editing & CRISPRi toolkit, enabling efficient genetic manipulation. Take a look 👉 pubs.acs.org/doi/10.1021/...
October 31, 2025 at 11:02 AM
Pseudomonas chlororaphis is a promising biofactory, but hard to engineer. A new piece of work has characterised its endogenous CRISPR/Cas I–F system and built a precise editing & CRISPRi toolkit, enabling efficient genetic manipulation. Take a look 👉 pubs.acs.org/doi/10.1021/...
Looking for efficient ways to program intercellular communication? 🧬
Researchers at Micalis Institute present a phagemid toolbox —with #SEVA-based variants— for DNA delivery and next-gen multicellular circuits.
👉 doi.org/10.1101/2025...
Researchers at Micalis Institute present a phagemid toolbox —with #SEVA-based variants— for DNA delivery and next-gen multicellular circuits.
👉 doi.org/10.1101/2025...
An M13 phagemid toolbox for engineering tuneable DNA communication in bacterial consortia
Intercellular communication is essential for distributed genetic circuits operating across cells in multicellular consortia. While diverse signalling molecules have been employed—ranging from quorum…
doi.org
October 29, 2025 at 11:03 AM
Looking for efficient ways to program intercellular communication? 🧬
Researchers at Micalis Institute present a phagemid toolbox —with #SEVA-based variants— for DNA delivery and next-gen multicellular circuits.
👉 doi.org/10.1101/2025...
Researchers at Micalis Institute present a phagemid toolbox —with #SEVA-based variants— for DNA delivery and next-gen multicellular circuits.
👉 doi.org/10.1101/2025...
The evolution of #SynBio advances with new regulatory toolboxes 🧬
This review explores devices from switches & logic gates to memory modules, powering circuits for bioproduction, therapeutics & biosafety — maybe you’ll find the ideal one for your research 👉 doi.org/10.3389/fsyb...
This review explores devices from switches & logic gates to memory modules, powering circuits for bioproduction, therapeutics & biosafety — maybe you’ll find the ideal one for your research 👉 doi.org/10.3389/fsyb...
Frontiers | Genetic circuits in synthetic biology: broadening the toolbox of regulatory devices
Devices sensing inputs and generating outputs are fundamental regulatory units, and as such are the basis of more complex regulatory networks. We provide an ...
doi.org
October 27, 2025 at 11:04 AM
The evolution of #SynBio advances with new regulatory toolboxes 🧬
This review explores devices from switches & logic gates to memory modules, powering circuits for bioproduction, therapeutics & biosafety — maybe you’ll find the ideal one for your research 👉 doi.org/10.3389/fsyb...
This review explores devices from switches & logic gates to memory modules, powering circuits for bioproduction, therapeutics & biosafety — maybe you’ll find the ideal one for your research 👉 doi.org/10.3389/fsyb...