Rosaura Brisuela
@roswitta.bsky.social
The abstract-Curiosity drive model for exploration,arts and science,Possibilian & "ʇsɐ!snɥʇuә u!ɐɹq" BLOG: https://www.facebook.com/profile.php?id=100029060183353
Reposted by Rosaura Brisuela
Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩
I’m excited to share this collaborative work with Prof. Dagmar Wachten (@wachtenlab.bsky.social), providing an accessible overview of primary cilia signalling and recent advances in cellular signaling in health and disease. Many thanks to Dagmar for a fantastic collaboration! doi.org/10.1242/jcs....
Primary cilia signalling at a glance
Summary: We explore the primary cilium as a master regulator of cellular communication that integrates diverse signalling pathways to guide development and maintain homeostasis. Its dysfunction trigge...
doi.org
October 30, 2025 at 1:11 PM
Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩
Reposted by Rosaura Brisuela
A single dose of #psilocybin induces a rapid and sustained reversal of both mechanical allodynia (pain) and anxiodepression-like states in adult male and female mice
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain - Nature Neuroscience
Hammo et al. show that a single dose of psilocybin rapidly and sustainably relieves both chronic pain and anxiodepressive-like behaviors in mice by restoring prefrontal activity through partial agonism at 5-HT2A and 5-HT1A receptors.
www.nature.com
October 7, 2025 at 5:31 PM
A single dose of #psilocybin induces a rapid and sustained reversal of both mechanical allodynia (pain) and anxiodepression-like states in adult male and female mice
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Rosaura Brisuela
Reposted by Rosaura Brisuela
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 6, 2025 at 5:52 PM
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Rosaura Brisuela
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
October 7, 2025 at 11:15 PM
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
Reposted by Rosaura Brisuela
Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...
Cracking organisms’ energy code
Researchers define rules governing how growing microorganisms use energy efficiently
www.mpi-cbg.de
October 7, 2025 at 9:31 AM
Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...
Reposted by Rosaura Brisuela
🧠📈 Do neurons of a feather flock together? Not quite.
New evidence shows that neurons of the same specific type tend to avoid each other in space, supporting the mosaic hypothesis in the cortex.
📄 Read the @cp-cellreports.bsky.social study: www.cell.com/cell-reports...
New evidence shows that neurons of the same specific type tend to avoid each other in space, supporting the mosaic hypothesis in the cortex.
📄 Read the @cp-cellreports.bsky.social study: www.cell.com/cell-reports...
October 7, 2025 at 11:18 PM
🧠📈 Do neurons of a feather flock together? Not quite.
New evidence shows that neurons of the same specific type tend to avoid each other in space, supporting the mosaic hypothesis in the cortex.
📄 Read the @cp-cellreports.bsky.social study: www.cell.com/cell-reports...
New evidence shows that neurons of the same specific type tend to avoid each other in space, supporting the mosaic hypothesis in the cortex.
📄 Read the @cp-cellreports.bsky.social study: www.cell.com/cell-reports...
Reposted by Rosaura Brisuela
When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...
The history and future of resting-state functional magnetic resonance imaging - Nature
This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...
www.nature.com
May 28, 2025 at 3:52 PM
When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...
Reposted by Rosaura Brisuela
Hey Keri, some nuclei wear their emotions on their chromatin 🤭 I’m sure this is not in any epigenetic text books. Ironically, I captured this on a Lattice Light Sheet microscope a few years back which protects cell from phototoxicity.
September 19, 2025 at 4:35 PM
Hey Keri, some nuclei wear their emotions on their chromatin 🤭 I’m sure this is not in any epigenetic text books. Ironically, I captured this on a Lattice Light Sheet microscope a few years back which protects cell from phototoxicity.
Reposted by Rosaura Brisuela
Field notes from a weekend PI at the #microscope: vesicle cargo lanes lighting up in real time like @FedEx. This is the ML1N PX domain in a fibroblast. Hot damn, there’s mind-blowing action under the surface of cells: this video shows 2 min of time 🤯 #Cellbio #MicroscopyMonday #SciArt #SciComm
September 22, 2025 at 3:42 PM
Field notes from a weekend PI at the #microscope: vesicle cargo lanes lighting up in real time like @FedEx. This is the ML1N PX domain in a fibroblast. Hot damn, there’s mind-blowing action under the surface of cells: this video shows 2 min of time 🤯 #Cellbio #MicroscopyMonday #SciArt #SciComm
Reposted by Rosaura Brisuela
Age-related microbiome metabolites modulate splicing and chromatin accessibility in the brain https://www.biorxiv.org/content/10.1101/2025.10.03.680371v1
October 5, 2025 at 9:15 PM
Age-related microbiome metabolites modulate splicing and chromatin accessibility in the brain https://www.biorxiv.org/content/10.1101/2025.10.03.680371v1
Reposted by Rosaura Brisuela
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:03 AM
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Reposted by Rosaura Brisuela
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:22 AM
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
Reposted by Rosaura Brisuela
Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy.
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
September 5, 2025 at 3:37 PM
Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy.
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
Reposted by Rosaura Brisuela
I wrote an article summarizing our recent findings of beta cell cilia - neuron contacts. It was fun to elaborate a bit on the exploration of #openaccess #volumeEM datasets: analyticalscience.wiley.com/content/arti...
Volume EM uncovers hidden tissue contacts - 2025 - Wiley Analytical Science
The largest repository of validated, free and subject-focused e-publications and online seminars in analytical science covering latest techniques, equipment, original research, editorials, and industr...
analyticalscience.wiley.com
September 15, 2025 at 12:24 PM
I wrote an article summarizing our recent findings of beta cell cilia - neuron contacts. It was fun to elaborate a bit on the exploration of #openaccess #volumeEM datasets: analyticalscience.wiley.com/content/arti...
Reposted by Rosaura Brisuela
Inside a cerebral organoid: a fluorescent lumen shines through 🧠✨ #FluorescenceFriday
September 26, 2025 at 3:59 PM
Inside a cerebral organoid: a fluorescent lumen shines through 🧠✨ #FluorescenceFriday
Reposted by Rosaura Brisuela
#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data
September 26, 2025 at 11:48 AM
#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data
Reposted by Rosaura Brisuela
Bringing some more ExM to #FluorescenceFriday with what appears to be a frustrated cell division in fibroblasts.
More details in Alt-text.
More details in Alt-text.
September 26, 2025 at 2:08 PM
Bringing some more ExM to #FluorescenceFriday with what appears to be a frustrated cell division in fibroblasts.
More details in Alt-text.
More details in Alt-text.
Reposted by Rosaura Brisuela
For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.
September 26, 2025 at 5:51 PM
For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.
Reposted by Rosaura Brisuela
Deep Learning-Based Control of Electrically Evoked Activity in Human Visual Cortex https://www.biorxiv.org/content/10.1101/2025.09.24.678361v1
September 26, 2025 at 11:15 PM
Deep Learning-Based Control of Electrically Evoked Activity in Human Visual Cortex https://www.biorxiv.org/content/10.1101/2025.09.24.678361v1
Heroico colegio militar mexicano #desfile2025
September 16, 2025 at 6:44 PM
Heroico colegio militar mexicano #desfile2025
Reposted by Rosaura Brisuela
Reposted by Rosaura Brisuela
One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...
August 22, 2025 at 5:32 PM
One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...
Reposted by Rosaura Brisuela
Thomas Deininger uses plastic waste to create sculptures,or should I say,works of Genius!!!!!!
August 23, 2025 at 4:41 AM
Thomas Deininger uses plastic waste to create sculptures,or should I say,works of Genius!!!!!!