Rashmi Priya
@rashmi-priya.bsky.social
Developmental Biologist I Organ Form and Function, Heart Morphogenesis I Group Leader @crick.ac.uk I India - Australia - Germany - UK
Pinned
Rashmi Priya
@rashmi-priya.bsky.social
· Mar 10
Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...
Adieu @tobyandrews.bsky.social you will be missed...
You’re off to an incredible start, and I couldn’t be prouder. Onward and upward!
You’re off to an incredible start, and I couldn’t be prouder. Onward and upward!
October 13, 2025 at 11:31 AM
Adieu @tobyandrews.bsky.social you will be missed...
You’re off to an incredible start, and I couldn’t be prouder. Onward and upward!
You’re off to an incredible start, and I couldn’t be prouder. Onward and upward!
Reposted by Rashmi Priya
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 2:06 PM
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Reposted by Rashmi Priya
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
October 8, 2025 at 1:05 PM
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
Reposted by Rashmi Priya
Our first extraordinary biologist featured this week is Katherine Brown, @biologists.bsky.social Publishing Director and former @dev-journal.bsky.social Executive Editor, who has been closely involved with @prelights.bsky.social since its inception. #100biologists
@katherine-brown.bsky.social
@katherine-brown.bsky.social
October 8, 2025 at 1:13 PM
Our first extraordinary biologist featured this week is Katherine Brown, @biologists.bsky.social Publishing Director and former @dev-journal.bsky.social Executive Editor, who has been closely involved with @prelights.bsky.social since its inception. #100biologists
@katherine-brown.bsky.social
@katherine-brown.bsky.social
Reposted by Rashmi Priya
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
October 7, 2025 at 11:57 AM
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
Reposted by Rashmi Priya
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
September 26, 2025 at 12:55 PM
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
Reposted by Rashmi Priya
Ventricle position can be remodeled after heart looping!
In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers.
So grateful to all the authors for their expertise and input during this long (but fun) ride 💪
Read more here ⬇️
In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers.
So grateful to all the authors for their expertise and input during this long (but fun) ride 💪
Read more here ⬇️
September 24, 2025 at 7:53 PM
Ventricle position can be remodeled after heart looping!
In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers.
So grateful to all the authors for their expertise and input during this long (but fun) ride 💪
Read more here ⬇️
In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers.
So grateful to all the authors for their expertise and input during this long (but fun) ride 💪
Read more here ⬇️
Reposted by Rashmi Priya
📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia.
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
September 19, 2025 at 6:25 PM
📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia.
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
Reposted by Rashmi Priya
In our Forest of Biologists we fund the restoration and preservation of ancient woodland and dedicate these trees to our peer reviewers.
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
September 19, 2025 at 10:58 AM
In our Forest of Biologists we fund the restoration and preservation of ancient woodland and dedicate these trees to our peer reviewers.
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
Development does not happen in isolation! Material properties, geometry, stiffness, fluid flows...can all steer how development unfolds. If you’re exploring these kinds of questions, we’d love to see your work @dev-journal.bsky.social
More info below ⬇️
More info below ⬇️
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
September 19, 2025 at 9:48 AM
Development does not happen in isolation! Material properties, geometry, stiffness, fluid flows...can all steer how development unfolds. If you’re exploring these kinds of questions, we’d love to see your work @dev-journal.bsky.social
More info below ⬇️
More info below ⬇️
Reposted by Rashmi Priya
Don't miss your chance to contribute to Development's next special issue, which takes a non-cell-centric approach to devbio, stem cells & regeneration. We hope to capture papers that discuss how secreted factors, external forces and the shape of spaces instruct development.
#DevSIextracellular
#DevSIextracellular
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
September 1, 2025 at 1:50 PM
Don't miss your chance to contribute to Development's next special issue, which takes a non-cell-centric approach to devbio, stem cells & regeneration. We hope to capture papers that discuss how secreted factors, external forces and the shape of spaces instruct development.
#DevSIextracellular
#DevSIextracellular
Reposted by Rashmi Priya
A snapshot of the mechanics shaping organs: what plants and animals can teach each other.
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
authors.elsevier.com
August 12, 2025 at 7:20 AM
A snapshot of the mechanics shaping organs: what plants and animals can teach each other.
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita
for putting this together.
authors.elsevier.com/a/1lamy3si8Q...
Reposted by Rashmi Priya
Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️
August 11, 2025 at 1:18 PM
Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️
Reposted by Rashmi Priya
Heading to the International Congress on Invertebrate Morphology in Chile? 😄
Don’t miss the talk by our PhD student Alena Kizenko on Aug 12, on how an ancient cytoskeletal gene found a new role in tunicate development 🧬 #EvoDevo #Invertebrates
🎥👇 Developing Phallusia embryo
Don’t miss the talk by our PhD student Alena Kizenko on Aug 12, on how an ancient cytoskeletal gene found a new role in tunicate development 🧬 #EvoDevo #Invertebrates
🎥👇 Developing Phallusia embryo
August 8, 2025 at 9:19 AM
Heading to the International Congress on Invertebrate Morphology in Chile? 😄
Don’t miss the talk by our PhD student Alena Kizenko on Aug 12, on how an ancient cytoskeletal gene found a new role in tunicate development 🧬 #EvoDevo #Invertebrates
🎥👇 Developing Phallusia embryo
Don’t miss the talk by our PhD student Alena Kizenko on Aug 12, on how an ancient cytoskeletal gene found a new role in tunicate development 🧬 #EvoDevo #Invertebrates
🎥👇 Developing Phallusia embryo
Reposted by Rashmi Priya
✨Development meets design in this embryonic chameleon lung 🫁 🦎. Smooth muscle swirls 🟣 and branching tips and cartilage 🟢 come together in reptilian lung morphogenesis. Image taken by @drkatiegoodwin.bsky.social 🔬🧪
#FluorescenceFriday #DevBio
#FluorescenceFriday #DevBio
August 8, 2025 at 1:11 PM
✨Development meets design in this embryonic chameleon lung 🫁 🦎. Smooth muscle swirls 🟣 and branching tips and cartilage 🟢 come together in reptilian lung morphogenesis. Image taken by @drkatiegoodwin.bsky.social 🔬🧪
#FluorescenceFriday #DevBio
#FluorescenceFriday #DevBio
Reposted by Rashmi Priya
Thank you @the-node.bsky.social for inviting me to write a 'Behind the Story' piece on our recent study!
Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis thenode.biologists.com/exploring-th...
Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis thenode.biologists.com/exploring-th...
Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis - the Node
Behind the Paper Story of “Combined forces of hydrostatic pressure and actin polymerisation drive endothelial tip cell migration and sprouting angiogenesis”.
thenode.biologists.com
April 2, 2025 at 8:11 PM
Thank you @the-node.bsky.social for inviting me to write a 'Behind the Story' piece on our recent study!
Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis thenode.biologists.com/exploring-th...
Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis thenode.biologists.com/exploring-th...
Reposted by Rashmi Priya
We wrote this introductory review on how concepts from dynamical systems can help us understand developmental biology, hope it’s useful to somebody! It was a lot of fun to put together, and great to collaborate with brilliant colleagues across theory and experiments
Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social in 2023. journals.biologists.com/dev/article/...
August 4, 2025 at 2:46 PM
We wrote this introductory review on how concepts from dynamical systems can help us understand developmental biology, hope it’s useful to somebody! It was a lot of fun to put together, and great to collaborate with brilliant colleagues across theory and experiments
Reposted by Rashmi Priya
We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum.
First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social
rdcu.be/ezBl7
First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social
rdcu.be/ezBl7
Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model
Nature Communications - Here the authors show that Plasmodium falciparum egress products disrupt endothelial barrier and activate JAK-STAT and interferon type response in a 3D blood-brain barrier...
rdcu.be
August 7, 2025 at 7:27 AM
We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum.
First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social
rdcu.be/ezBl7
First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social
rdcu.be/ezBl7
Out now! Our very first paper@crick.ac.uk, an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️
www.cell.com/developmenta...
www.cell.com/developmenta...
August 6, 2025 at 4:36 PM
Out now! Our very first paper@crick.ac.uk, an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️
www.cell.com/developmenta...
www.cell.com/developmenta...
Reposted by Rashmi Priya
Researchers at the Crick have discovered that the heart’s contractions trigger biological signals for its own development.
Their study in zebrafish highlights the heart’s ability to remodel itself in response to biological challenges.
www.crick.ac.uk/news/2025-08...
Their study in zebrafish highlights the heart’s ability to remodel itself in response to biological challenges.
www.crick.ac.uk/news/2025-08...
Investigating the rhythm of heart development
New research in zebrafish shows how embryos build a functional heart that keeps beating for life.
www.crick.ac.uk
August 6, 2025 at 3:18 PM
Researchers at the Crick have discovered that the heart’s contractions trigger biological signals for its own development.
Their study in zebrafish highlights the heart’s ability to remodel itself in response to biological challenges.
www.crick.ac.uk/news/2025-08...
Their study in zebrafish highlights the heart’s ability to remodel itself in response to biological challenges.
www.crick.ac.uk/news/2025-08...
Reposted by Rashmi Priya
Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
August 6, 2025 at 1:09 PM
Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
Reposted by Rashmi Priya
My Pathway to Independence interview is now live on @dev-journal.bsky.social ! I had a great time speaking with @amjeve.bsky.social about my research journey and what's ahead journals.biologists.com/dev/article/...
Pathway to Independence – an interview with Giulia Paci
Giulia Paci is a Postdoctoral Fellow at the Laboratory for Molecular Cell Biology at University College London, UK, supported by Yanlan Mao and Buzz Baum, who is interested in how developmental progra...
journals.biologists.com
August 5, 2025 at 9:06 AM
My Pathway to Independence interview is now live on @dev-journal.bsky.social ! I had a great time speaking with @amjeve.bsky.social about my research journey and what's ahead journals.biologists.com/dev/article/...
Reposted by Rashmi Priya
Happy to share our work on the role of biomechanical PULSATILITY on lung vessels.
Following surgery to alleviate overload in kids with single ventricle hearts, lung arteries form AVMs. #DevBio #EndothelialCell #CHD
Beautiful work from Steve Spurgin. #DevBio 🫁 🫀 ❤️🩹
www.biorxiv.org/content/10.1...
Following surgery to alleviate overload in kids with single ventricle hearts, lung arteries form AVMs. #DevBio #EndothelialCell #CHD
Beautiful work from Steve Spurgin. #DevBio 🫁 🫀 ❤️🩹
www.biorxiv.org/content/10.1...
Pulsatile flow dynamics determine pulmonary arterial architecture
BACKGROUND Single ventricle congenital heart disease (SV-CHD) is a uniformly lethal condition. Survival depends upon the Glenn surgery, which shunts venous blood directly to the pulmonary arteries wit...
www.biorxiv.org
August 1, 2025 at 11:25 AM
Happy to share our work on the role of biomechanical PULSATILITY on lung vessels.
Following surgery to alleviate overload in kids with single ventricle hearts, lung arteries form AVMs. #DevBio #EndothelialCell #CHD
Beautiful work from Steve Spurgin. #DevBio 🫁 🫀 ❤️🩹
www.biorxiv.org/content/10.1...
Following surgery to alleviate overload in kids with single ventricle hearts, lung arteries form AVMs. #DevBio #EndothelialCell #CHD
Beautiful work from Steve Spurgin. #DevBio 🫁 🫀 ❤️🩹
www.biorxiv.org/content/10.1...
Reposted by Rashmi Priya
Transitions in development – an interview with Jeffrey Farrell
@jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches.
journals.biologists.com/dev/article/...
@jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches.
journals.biologists.com/dev/article/...
July 28, 2025 at 4:06 PM
Transitions in development – an interview with Jeffrey Farrell
@jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches.
journals.biologists.com/dev/article/...
@jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches.
journals.biologists.com/dev/article/...
Reposted by Rashmi Priya
Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...
Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs
Menchero et al. generate a single-cell transcriptomic atlas in the opossum and show
rapid progression of transcriptional programs in specific tissues relative to morphological
landmarks. This shift in...
www.cell.com
July 24, 2025 at 5:07 PM
Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...