@phil100.bsky.social
Mr 100 on twitter.
Investor in ONT, IPGroup, OBI, etc
Investor in ONT, IPGroup, OBI, etc
Reposted
We are recruiting sewersheds for an expanding project. Basically, we want to learn everything that can be learned from wastewater.
Read on if you are interested.
1/
Read on if you are interested.
1/
April 20, 2025 at 8:11 PM
We are recruiting sewersheds for an expanding project. Basically, we want to learn everything that can be learned from wastewater.
Read on if you are interested.
1/
Read on if you are interested.
1/
Reposted
Now it’s @drneilstone.bsky.social talking about social media and medicine. “Bluesky is the dominant platform now.”
He said it. We will get him over to Bluesky for good! 💪🏼😉😁
#ESCMIDGlobal
#IDSky #MedSky
He said it. We will get him over to Bluesky for good! 💪🏼😉😁
#ESCMIDGlobal
#IDSky #MedSky
April 15, 2025 at 7:31 AM
Now it’s @drneilstone.bsky.social talking about social media and medicine. “Bluesky is the dominant platform now.”
He said it. We will get him over to Bluesky for good! 💪🏼😉😁
#ESCMIDGlobal
#IDSky #MedSky
He said it. We will get him over to Bluesky for good! 💪🏼😉😁
#ESCMIDGlobal
#IDSky #MedSky
Reposted
🧧🧧🧧🧧 So another exciting finding for the weekend before I go on vacation.
*FFPE Ligation Sequencing for ALL!*
For a long while it was thought that ligation (i.e. native DNA) sequencing on @nanoporetech.com was difficult, if not impossible.
*FFPE Ligation Sequencing for ALL!*
For a long while it was thought that ligation (i.e. native DNA) sequencing on @nanoporetech.com was difficult, if not impossible.
April 13, 2025 at 8:30 AM
🧧🧧🧧🧧 So another exciting finding for the weekend before I go on vacation.
*FFPE Ligation Sequencing for ALL!*
For a long while it was thought that ligation (i.e. native DNA) sequencing on @nanoporetech.com was difficult, if not impossible.
*FFPE Ligation Sequencing for ALL!*
For a long while it was thought that ligation (i.e. native DNA) sequencing on @nanoporetech.com was difficult, if not impossible.
Reposted
Congrats Hasindu and Nanopore Garvan team. This is an exciting development. I remember asking myself how AS might be used when it was first released. You have truely answered this 🙌🎉
Introducing cornetto, an adaptive genome assembly paradigm using @nanoporetech.com adaptive sampling.
- greatly reduces cost per genome assembly
- reference agnostic, so works for non-humans
- assembly just using saliva
- & many more
Relies on 2 excellent software #readfish & #hifiasm.
- greatly reduces cost per genome assembly
- reference agnostic, so works for non-humans
- assembly just using saliva
- & many more
Relies on 2 excellent software #readfish & #hifiasm.
Adaptively integrated sequencing and assembly of near-complete genomes https://www.biorxiv.org/content/10.1101/2025.03.31.646505v1
April 5, 2025 at 10:51 PM
Congrats Hasindu and Nanopore Garvan team. This is an exciting development. I remember asking myself how AS might be used when it was first released. You have truely answered this 🙌🎉
Reposted
happy nanoversary to me! i had totally forgotten that three years ago today i started my nanopore adventure by testing positive for covid and isolating in my office
April 1, 2025 at 4:12 PM
happy nanoversary to me! i had totally forgotten that three years ago today i started my nanopore adventure by testing positive for covid and isolating in my office
Reposted
A long time coming, but our @nanoporetech.com P2Solo is finally running. Time to dive deeper into the messy unknown, hunt down mysterious pathogens, and maybe even find some shiny new viruses. Let's do this. 🦇🐓🧪🦠🧬🔬 #Nanopore #VirusHunting #Science #OneHealth #Genomics
April 2, 2025 at 11:03 AM
A long time coming, but our @nanoporetech.com P2Solo is finally running. Time to dive deeper into the messy unknown, hunt down mysterious pathogens, and maybe even find some shiny new viruses. Let's do this. 🦇🐓🧪🦠🧬🔬 #Nanopore #VirusHunting #Science #OneHealth #Genomics
Reposted
"right now it seems to me that the competition can do most of the things that Oxford Nanopore can"
* cough *
- minimum setup cost of less than $10,000
- minimum run cost of less than $100
- minimum turnaround time of less than 1h
- RNA methylation
- reads longer than 100kb
- sequencing in space
* cough *
- minimum setup cost of less than $10,000
- minimum run cost of less than $100
- minimum turnaround time of less than 1h
- RNA methylation
- reads longer than 100kb
- sequencing in space
March 22, 2025 at 6:31 PM
"right now it seems to me that the competition can do most of the things that Oxford Nanopore can"
* cough *
- minimum setup cost of less than $10,000
- minimum run cost of less than $100
- minimum turnaround time of less than 1h
- RNA methylation
- reads longer than 100kb
- sequencing in space
* cough *
- minimum setup cost of less than $10,000
- minimum run cost of less than $100
- minimum turnaround time of less than 1h
- RNA methylation
- reads longer than 100kb
- sequencing in space
Reposted
This is a curious one - real time hashing of raw nanopore signals, building up to a whole de-novo assembly based on the 'squiggles'. This skips basecalls entirely. What do people think about this approach?
💻🧬
💻🧬
search. Rawsamble enables the construction of de novo assemblies directly from raw signals without basecalling, which opens up new directions and uses for raw nanopore signal analysis. [8/8 of https://arxiv.org/abs/2503.02997v1]
March 22, 2025 at 5:46 AM
This is a curious one - real time hashing of raw nanopore signals, building up to a whole de-novo assembly based on the 'squiggles'. This skips basecalls entirely. What do people think about this approach?
💻🧬
💻🧬
Reposted
“Back then, the overwhelming public sentiment was: never again. Today, it seems: never what?”—Siddhartha Mukherjee
Exceptional essay
Gift link
www.nytimes.com/2025/03/10/o...
Exceptional essay
Gift link
www.nytimes.com/2025/03/10/o...
Opinion | Covid’s Deadliest Effect Took Five Years to Appear (Gift Article)
What once belonged to all of us now belongs to corporations.
www.nytimes.com
March 16, 2025 at 3:58 PM
“Back then, the overwhelming public sentiment was: never again. Today, it seems: never what?”—Siddhartha Mukherjee
Exceptional essay
Gift link
www.nytimes.com/2025/03/10/o...
Exceptional essay
Gift link
www.nytimes.com/2025/03/10/o...
Reposted
#Breaking - WHO issues starkest warning yet on fallout from U.S. withdrawal of aid for global health
WHO issues starkest warning yet on fallout from U.S. withdrawal of aid for global health
Breaking: The WHO issued its starkest warning yet on the consequences of the abrupt cessation of U.S. global health funding, saying it is threatening to reverse years of progress worldwide.
buff.ly
March 17, 2025 at 4:29 PM
#Breaking - WHO issues starkest warning yet on fallout from U.S. withdrawal of aid for global health
Reposted
Reposted
BTW, we have a website that will display all of this data that we are planning to launch very soon. Stay tuned.
5/5
5/5
February 28, 2025 at 4:33 PM
BTW, we have a website that will display all of this data that we are planning to launch very soon. Stay tuned.
5/5
5/5
Reposted
If you like building tools for scientists like this, come join us! plasmidsaurus.com/careers
February 25, 2025 at 5:03 PM
If you like building tools for scientists like this, come join us! plasmidsaurus.com/careers
Reposted
Overdue for my annual #AGBT haberdashery communique
This year I’m sporting this wonderful cap @biomath.bsky.social gifted me last year.
There might be a few more around, but if you accidentally mistake another for me - any friend of Charlie’s is an interesting new contact! 🧬🖥️
This year I’m sporting this wonderful cap @biomath.bsky.social gifted me last year.
There might be a few more around, but if you accidentally mistake another for me - any friend of Charlie’s is an interesting new contact! 🧬🖥️
February 23, 2025 at 10:09 PM
Overdue for my annual #AGBT haberdashery communique
This year I’m sporting this wonderful cap @biomath.bsky.social gifted me last year.
There might be a few more around, but if you accidentally mistake another for me - any friend of Charlie’s is an interesting new contact! 🧬🖥️
This year I’m sporting this wonderful cap @biomath.bsky.social gifted me last year.
There might be a few more around, but if you accidentally mistake another for me - any friend of Charlie’s is an interesting new contact! 🧬🖥️
Reposted
De tuin vindt dat het voorjaar is
February 23, 2025 at 2:09 PM
De tuin vindt dat het voorjaar is
Reposted
Roche Ripple Predictions
My take on how Roche SBX will roil the sequencing landscape
omicsomics.blogspot.com/2025/02/roch...
🧬🖥️
My take on how Roche SBX will roil the sequencing landscape
omicsomics.blogspot.com/2025/02/roch...
🧬🖥️
Roche Ripple Predictions
In the prior piece , I covered the technical details unveiled by Roche for their SBX technology, but generally tried to avoid predicting its...
omicsomics.blogspot.com
February 20, 2025 at 6:40 PM
Roche Ripple Predictions
My take on how Roche SBX will roil the sequencing landscape
omicsomics.blogspot.com/2025/02/roch...
🧬🖥️
My take on how Roche SBX will roil the sequencing landscape
omicsomics.blogspot.com/2025/02/roch...
🧬🖥️
Reposted
m.genome.cshlp.org/content/earl... Matt Loose in Nottingham publishes a method for Adaptive Sampling with Oxford @nanoporetech.com sequencing.
Genome Res | Mobile
m.genome.cshlp.org
February 18, 2025 at 5:26 PM
m.genome.cshlp.org/content/earl... Matt Loose in Nottingham publishes a method for Adaptive Sampling with Oxford @nanoporetech.com sequencing.
Reposted
That peak? The one in 1962/1963? That was when the United States of America spent 2.5% of GDP in federal dollars on SCIENCE.
That peak in spending gave us our entire economy as we currently understand it. Composites, integrated circuits, lasers, advanced fabrics, biotech, etc... Time to reinvest.
That peak in spending gave us our entire economy as we currently understand it. Composites, integrated circuits, lasers, advanced fabrics, biotech, etc... Time to reinvest.
Changes in NASA's workforce, by year, since 1959. Today will mark the largest involuntary reduction in staffing since the end of Apollo. The difference is that, right now, NASA is trying to spin up a Moon program instead of end one.
February 18, 2025 at 5:55 PM
That peak? The one in 1962/1963? That was when the United States of America spent 2.5% of GDP in federal dollars on SCIENCE.
That peak in spending gave us our entire economy as we currently understand it. Composites, integrated circuits, lasers, advanced fabrics, biotech, etc... Time to reinvest.
That peak in spending gave us our entire economy as we currently understand it. Composites, integrated circuits, lasers, advanced fabrics, biotech, etc... Time to reinvest.
Reposted
This is the thing about basic science…
You never know where it will lead, and you cannot presuppose what commercial product comes out of it.
They don’t tend to award Nobel Prizes for translational science. They award them for basic, often exploratory science.
You never know where it will lead, and you cannot presuppose what commercial product comes out of it.
They don’t tend to award Nobel Prizes for translational science. They award them for basic, often exploratory science.
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
February 9, 2025 at 10:04 PM
This is the thing about basic science…
You never know where it will lead, and you cannot presuppose what commercial product comes out of it.
They don’t tend to award Nobel Prizes for translational science. They award them for basic, often exploratory science.
You never know where it will lead, and you cannot presuppose what commercial product comes out of it.
They don’t tend to award Nobel Prizes for translational science. They award them for basic, often exploratory science.
Reposted
BRUH
My plasmid samples arrived at 8am on a ***saturday***
Delivery to data in 50mins?!
My plasmid samples arrived at 8am on a ***saturday***
Delivery to data in 50mins?!
February 15, 2025 at 6:46 PM
BRUH
My plasmid samples arrived at 8am on a ***saturday***
Delivery to data in 50mins?!
My plasmid samples arrived at 8am on a ***saturday***
Delivery to data in 50mins?!
Reposted
Hi everyone on Bluesky working in #genomics #NGS. Today is Valentines day. How many of you are more excited about Feb 20th?!
Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina
enseqlopedia.com/2025/02/roch...
Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina
enseqlopedia.com/2025/02/roch...
Roche emerges from the Lazarus pit
Is Roche going to "knock it out of the park" or "jump the shark"? Everyone I know is excited, even if many of them are sceptical, about the Feb 20th webinar and what we will learn about SBX. Alex Dick...
enseqlopedia.com
February 14, 2025 at 10:46 AM
Hi everyone on Bluesky working in #genomics #NGS. Today is Valentines day. How many of you are more excited about Feb 20th?!
Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina
enseqlopedia.com/2025/02/roch...
Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina
enseqlopedia.com/2025/02/roch...
Reposted
What's happening with the Covid nasal vaccine programs?
And why are they in jeopardy?
erictopol.substack.com/p/a-covid-na...
And why are they in jeopardy?
erictopol.substack.com/p/a-covid-na...
A Covid Nasal Vaccine Update
Now 6 Ongoing Clinical Trials in the United States
erictopol.substack.com
February 14, 2025 at 4:17 PM
What's happening with the Covid nasal vaccine programs?
And why are they in jeopardy?
erictopol.substack.com/p/a-covid-na...
And why are they in jeopardy?
erictopol.substack.com/p/a-covid-na...
Reposted
Hello @ukhsa.bsky.social !!! Welcome to Bluesky! ❤️
We have published new #Norovirus data today showing cases are 117% above the 5-season average. Lots of people are getting sick with the winter vomiting bug. 📈
Learn about managing the virus in our blog post 👀
ukhsa.blog.gov.uk/2022/11/17/n...
Full report here 👇
www.gov.uk/government/s...
Learn about managing the virus in our blog post 👀
ukhsa.blog.gov.uk/2022/11/17/n...
Full report here 👇
www.gov.uk/government/s...
February 13, 2025 at 8:30 PM
Hello @ukhsa.bsky.social !!! Welcome to Bluesky! ❤️
Reposted
📌The need for speed: ultra-rapid high-resolution outbreak analysis in a front-line hospital microbiology laboratory |@medrxivpreprint
See how hospital labs can analyse outbreaks fast - no on-site #Bioinformatics needed, cutting delays
doi.org/10.1101/2025...
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
See how hospital labs can analyse outbreaks fast - no on-site #Bioinformatics needed, cutting delays
doi.org/10.1101/2025...
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
The need for speed: ultra-rapid high-resolution outbreak analysis in a front-line hospital microbiology laboratory
Many hospital laboratories have technical capacity to perform whole-genome sequencing but lack bioinformatic expertise to analyse sequence data. Sending isolates to reference laboratories creates dela...
doi.org
February 13, 2025 at 9:30 PM
📌The need for speed: ultra-rapid high-resolution outbreak analysis in a front-line hospital microbiology laboratory |@medrxivpreprint
See how hospital labs can analyse outbreaks fast - no on-site #Bioinformatics needed, cutting delays
doi.org/10.1101/2025...
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
See how hospital labs can analyse outbreaks fast - no on-site #Bioinformatics needed, cutting delays
doi.org/10.1101/2025...
🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠