Nik Copeland
@nikcopeland.bsky.social
Dad, scientist, DNA enthusiast and cancer research at Lancaster University.
Reposted by Nik Copeland
We’re delighted to host Dr Natalie Kenny, multi-award-winning scientist and CEO/founder of BioGrad, for a special guest lecture.
#Biotech #CellTherapy #RegenerativeMedicine #STEMEducation #ScienceInnovation
#Biotech #CellTherapy #RegenerativeMedicine #STEMEducation #ScienceInnovation
December 2, 2025 at 8:07 AM
We’re delighted to host Dr Natalie Kenny, multi-award-winning scientist and CEO/founder of BioGrad, for a special guest lecture.
#Biotech #CellTherapy #RegenerativeMedicine #STEMEducation #ScienceInnovation
#Biotech #CellTherapy #RegenerativeMedicine #STEMEducation #ScienceInnovation
Reposted by Nik Copeland
I’m really pleased to share the link to a new Cook Lab paper published today in Nature Communications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
RAF inhibitors activate the integrated stress response by direct activation of GCN2 - Nature Communications
Three BRAF inhibitors are used to treat melanoma and colorectal cancer. Here, the authors demonstrate that these drugs bind and activate the protein kinase GCN2, a previously unappreciated off-target ...
www.nature.com
November 17, 2025 at 12:12 PM
I’m really pleased to share the link to a new Cook Lab paper published today in Nature Communications.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nik Copeland
Béla Novák (1956–2025) – a legacy of scientific discovery and personal charm
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
October 17, 2025 at 2:02 PM
Béla Novák (1956–2025) – a legacy of scientific discovery and personal charm
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
Alexis Barr, Francis Barr and John Tyson remember Béla Novák.
journals.biologists.com/jcs/article/...
Reposted by Nik Copeland
🚨 Funded PhD Studentship 🚨
Antibody Engineering & Plant Molecular Farming for Aquaculture Health
📍 Lancaster & Glasgow | BBSRC NWBio DTP
🗓 Apply by 21 Nov 2025
👉 Engineer antibodies vs Vibrio
👉 Develop rapid diagnostics
👉 Explore plant-based biologics for fish health
Antibody Engineering & Plant Molecular Farming for Aquaculture Health
📍 Lancaster & Glasgow | BBSRC NWBio DTP
🗓 Apply by 21 Nov 2025
👉 Engineer antibodies vs Vibrio
👉 Develop rapid diagnostics
👉 Explore plant-based biologics for fish health
October 3, 2025 at 12:24 PM
🚨 Funded PhD Studentship 🚨
Antibody Engineering & Plant Molecular Farming for Aquaculture Health
📍 Lancaster & Glasgow | BBSRC NWBio DTP
🗓 Apply by 21 Nov 2025
👉 Engineer antibodies vs Vibrio
👉 Develop rapid diagnostics
👉 Explore plant-based biologics for fish health
Antibody Engineering & Plant Molecular Farming for Aquaculture Health
📍 Lancaster & Glasgow | BBSRC NWBio DTP
🗓 Apply by 21 Nov 2025
👉 Engineer antibodies vs Vibrio
👉 Develop rapid diagnostics
👉 Explore plant-based biologics for fish health
Reposted by Nik Copeland
Postdoc positions open in my lab (Francis Crick Institute) to study
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
June 20, 2025 at 9:38 AM
Postdoc positions open in my lab (Francis Crick Institute) to study
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
1. initiation of DNA replication.
2. chromatin replication/epigenetic inheritance.
Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.
Deadline 3 August 2025.
crick.wd3.myworkdayjobs.com/External/job...
Reposted by Nik Copeland
Is this a reference to its Kcat?
(If you ‘get’ this there may be a place for you in the Cook lab!😉)
(If you ‘get’ this there may be a place for you in the Cook lab!😉)
June 20, 2025 at 11:00 AM
Is this a reference to its Kcat?
(If you ‘get’ this there may be a place for you in the Cook lab!😉)
(If you ‘get’ this there may be a place for you in the Cook lab!😉)
Reposted by Nik Copeland
A 4% pay uplift, less than current inflation, is an insult to doctors in England. This Government has shown it simply doesn’t value doctors.
“The DDRB has failed doctors. If this is the best they can do, government needs to think again” says @drphilbanfield.bsky.social
“The DDRB has failed doctors. If this is the best they can do, government needs to think again” says @drphilbanfield.bsky.social
May 22, 2025 at 1:32 PM
A 4% pay uplift, less than current inflation, is an insult to doctors in England. This Government has shown it simply doesn’t value doctors.
“The DDRB has failed doctors. If this is the best they can do, government needs to think again” says @drphilbanfield.bsky.social
“The DDRB has failed doctors. If this is the best they can do, government needs to think again” says @drphilbanfield.bsky.social
Reposted by Nik Copeland
Got any great final year students who love the bench but don't (yet) want to do a PhD? I'm looking for a research technician to join our amazing AVERT team for the last 2 years of the project - a great chance to develop lab skills while supporting our team in York.
jobs.york.ac.uk/vacancy/rese...
jobs.york.ac.uk/vacancy/rese...
Jobs - The University of York
jobs.york.ac.uk
May 12, 2025 at 7:09 PM
Got any great final year students who love the bench but don't (yet) want to do a PhD? I'm looking for a research technician to join our amazing AVERT team for the last 2 years of the project - a great chance to develop lab skills while supporting our team in York.
jobs.york.ac.uk/vacancy/rese...
jobs.york.ac.uk/vacancy/rese...
Reposted by Nik Copeland
Final week for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts. #SGP25 @BiochemSoc @SmallGTPases Register here: bit.ly/SmallG25
Small G proteins in cellular signalling and disease 2025
bit.ly
April 22, 2025 at 4:58 PM
Final week for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts. #SGP25 @BiochemSoc @SmallGTPases Register here: bit.ly/SmallG25
A friend is running the London marathon in memory of her sister. I let her in the lab earlier to make a TikTok…I was fun but a little out of my comfort zone
April 12, 2025 at 11:37 AM
A friend is running the London marathon in memory of her sister. I let her in the lab earlier to make a TikTok…I was fun but a little out of my comfort zone
Reposted by Nik Copeland
British Steel employs 3.6k people. Coventry Uni group, which auditors say may not survive, employs 7.7k. But there is an emergency debate in parliament for British Steel and nothing for the whole HE sector imploding
Why is the government and the news so indifferent to the meltdown happening in UK #HigherEd right now?
Our universities are the envy of the world. Yet we are at risk of losing a generation of academics and damaging the sector beyond repair.
Our universities are the envy of the world. Yet we are at risk of losing a generation of academics and damaging the sector beyond repair.
The UK car industry contributes £22bn to the economy and employs c 35k people.
Universities contribute £265bn and employ nearly 400k, over 10x as much.
Yet he seems ok to let that sector implode.
Universities contribute £265bn and employ nearly 400k, over 10x as much.
Yet he seems ok to let that sector implode.
April 12, 2025 at 7:47 AM
British Steel employs 3.6k people. Coventry Uni group, which auditors say may not survive, employs 7.7k. But there is an emergency debate in parliament for British Steel and nothing for the whole HE sector imploding
Reposted by Nik Copeland
Campus in the City is taking place NOW at More Music in #Morecambe! Come and learn about #DNA and discover how #biology helps solve crimes. #CITC2025 #SparkYourCuriosity #LoveLancaster #CultureLancaster #MBCultureResearch
April 11, 2025 at 9:59 AM
Campus in the City is taking place NOW at More Music in #Morecambe! Come and learn about #DNA and discover how #biology helps solve crimes. #CITC2025 #SparkYourCuriosity #LoveLancaster #CultureLancaster #MBCultureResearch
Reposted by Nik Copeland
We have written a News&Views piece in @natsmb.nature.com on a recent paper by @buissonlab.bsky.social. Their work adds transcription stress to the landscape of danger signals detected by the innate immune system.
Link for free access here: rdcu.be/ehkTV
Link for free access here: rdcu.be/ehkTV
April 11, 2025 at 1:35 PM
We have written a News&Views piece in @natsmb.nature.com on a recent paper by @buissonlab.bsky.social. Their work adds transcription stress to the landscape of danger signals detected by the innate immune system.
Link for free access here: rdcu.be/ehkTV
Link for free access here: rdcu.be/ehkTV
Reposted by Nik Copeland
New online: Transcription stress causes an inflammatory response via release of IL-1α
Transcription stress causes an inflammatory response via release of IL-1α
Nature Structural & Molecular Biology, Published online: 11 April 2025; doi:10.1038/s41594-025-01525-5DNA damage can be sensed as a danger signal by the innate immune system. Bournique et al. show that the transcription stress caused by DNA lesions can also initiate inflammation by causing the direct release of cytokine IL-1α, which then drives NF-κB activation in neighboring cells.
go.nature.com
April 11, 2025 at 11:53 AM
New online: Transcription stress causes an inflammatory response via release of IL-1α
Reposted by Nik Copeland
Huge congratulations to two of our lecturers Dr Sana Hannan @sanahannan.bsky.social and Dr Katerina Gatsiou who have been awarded funding from the Academy of Medical Sciences Springboard programme @acmedsci.bsky.social #Springboard25 (1/4) 🧪
April 11, 2025 at 8:32 AM
Huge congratulations to two of our lecturers Dr Sana Hannan @sanahannan.bsky.social and Dr Katerina Gatsiou who have been awarded funding from the Academy of Medical Sciences Springboard programme @acmedsci.bsky.social #Springboard25 (1/4) 🧪
Reposted by Nik Copeland
Pre-print alert! Together with @stapleslab.bsky.social and @cejkalab.bsky.social we find that IFI16 binds to stalled replication forks where it acts as innate immune sensor for replication stress, and protects the nascent DNA from degradation. 👇👇
New preprint from the lab, revealing new roles for IFI16 during replication stress. Great collab with @unterholznerlab.bsky.social and @cejkalab.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
IFI16 senses and protects stalled replication forks
Replication stress is a key driver of DNA damage and genome instability. Replication stress-induced fork remodelling generates a new DNA end that is vulnerable to the action of nucleases, and which is...
www.biorxiv.org
April 10, 2025 at 7:23 AM
Pre-print alert! Together with @stapleslab.bsky.social and @cejkalab.bsky.social we find that IFI16 binds to stalled replication forks where it acts as innate immune sensor for replication stress, and protects the nascent DNA from degradation. 👇👇
Reposted by Nik Copeland
Excited to announce the Emerging Innovators Fellowship for outstanding scientists of black heritage @mrc-lms.bsky.social
If you’re interested in applying & have a passion for cell cycle control or quiescence, do get in touch
Please circulate!
If you’re interested in applying & have a passion for cell cycle control or quiescence, do get in touch
Please circulate!
We’re thrilled to introduce our Emerging Innovators Fellowship, a new 3-year fully-funded postdoctoral fellowship designed to support scientists from Black heritage backgrounds.
Register now for our introductory Webinar on Tuesday 8th April at 9am!
Register now for our introductory Webinar on Tuesday 8th April at 9am!
LMS Emerging Innovators Fellowship Introductory Webinar
Join the LMS for an online session to learn more about our Emerging Innovators Fellowship for postdocs of Black heritage and how to apply
www.eventbrite.co.uk
April 3, 2025 at 3:12 PM
Excited to announce the Emerging Innovators Fellowship for outstanding scientists of black heritage @mrc-lms.bsky.social
If you’re interested in applying & have a passion for cell cycle control or quiescence, do get in touch
Please circulate!
If you’re interested in applying & have a passion for cell cycle control or quiescence, do get in touch
Please circulate!
Reposted by Nik Copeland
Pls repost. Postdoc role on post-replicative ssDNA gap processing. Interesting models that should float replication aficionados boats. DM or c.staples@bangor.ac.uk for info. Until Dec26 but will strive for funding to provide continuity.
Fantastic place to live+work
www.jobs.ac.uk/job/DMG682/r...
Fantastic place to live+work
www.jobs.ac.uk/job/DMG682/r...
March 24, 2025 at 6:28 PM
Pls repost. Postdoc role on post-replicative ssDNA gap processing. Interesting models that should float replication aficionados boats. DM or c.staples@bangor.ac.uk for info. Until Dec26 but will strive for funding to provide continuity.
Fantastic place to live+work
www.jobs.ac.uk/job/DMG682/r...
Fantastic place to live+work
www.jobs.ac.uk/job/DMG682/r...
Reposted by Nik Copeland
Exciting #PhD opportunity to synthesise & test novel PROTACs/Targeted Protein Degraders for #Alzheimer's disease. Collaboration between María Paz Muñoz, Neil Dawson, Ed Parkin and @fieldinglab.bsky.social 🧪https://www.findaphd.com/phds/programme/natural-sciences-phd-opportunities/?p6417
Natural Sciences PhD opportunities at Lancaster University on FindAPhD.com
PhD Programme - Natural Sciences PhD opportunities at Lancaster University, listed on FindAPhD.com
www.findaphd.com
March 17, 2025 at 6:25 PM
Exciting #PhD opportunity to synthesise & test novel PROTACs/Targeted Protein Degraders for #Alzheimer's disease. Collaboration between María Paz Muñoz, Neil Dawson, Ed Parkin and @fieldinglab.bsky.social 🧪https://www.findaphd.com/phds/programme/natural-sciences-phd-opportunities/?p6417
Reposted by Nik Copeland
But, what about the banana bread!
Gene-edited non-browning banana could cut food waste, scientists say
Gene-edited non-browning banana could cut food waste, scientists say
Fruit variety developed in Norwich remains fresh for up to 12 hours after being peeled
Many of us have been guilty of binning a mushy, overripe banana – but now scientists say they have a solution with the launch of a genetically engineered non-browning…
www.theguardian.com
March 7, 2025 at 4:38 PM
But, what about the banana bread!
Reposted by Nik Copeland
A new PhD position is available in my lab to explore DNA replication mechanisms using single-molecule approaches. Apply by 19th of March:
www.crick.ac.uk/careers-stud...
www.crick.ac.uk/careers-stud...
Yardimci Lab | Single-molecule visualisation of the eukaryotic replication machinery
www.crick.ac.uk
March 4, 2025 at 11:39 AM
A new PhD position is available in my lab to explore DNA replication mechanisms using single-molecule approaches. Apply by 19th of March:
www.crick.ac.uk/careers-stud...
www.crick.ac.uk/careers-stud...
Reposted by Nik Copeland
Excited to start my lab at the University of Edinburgh studying sulfur metabolism in apicomplexan parasites. Kindly supported by an MRC Career Development Award.
Watch this space for job opportunities!
Watch this space for job opportunities!
March 4, 2025 at 11:45 AM
Excited to start my lab at the University of Edinburgh studying sulfur metabolism in apicomplexan parasites. Kindly supported by an MRC Career Development Award.
Watch this space for job opportunities!
Watch this space for job opportunities!
Reposted by Nik Copeland
🧬Fully funded PhD opportunity🔬Interested in the weird and wonderful #mitochondria in #parasites? This could be for you!
🌍 @blslancasteruni.bsky.social a UK Top 3 Biomedical Sciences Department
📌UK-based students only
⏱️Deadline 28th March
📮More info and to apply👇
www.findaphd.com/phds/project...
🌍 @blslancasteruni.bsky.social a UK Top 3 Biomedical Sciences Department
📌UK-based students only
⏱️Deadline 28th March
📮More info and to apply👇
www.findaphd.com/phds/project...
Staying alive: how do trypanosome parasite mitochondria deal with stress? at Lancaster University on FindAPhD.com
PhD Project - Staying alive: how do trypanosome parasite mitochondria deal with stress? at Lancaster University, listed on FindAPhD.com
www.findaphd.com
February 18, 2025 at 6:34 PM
🧬Fully funded PhD opportunity🔬Interested in the weird and wonderful #mitochondria in #parasites? This could be for you!
🌍 @blslancasteruni.bsky.social a UK Top 3 Biomedical Sciences Department
📌UK-based students only
⏱️Deadline 28th March
📮More info and to apply👇
www.findaphd.com/phds/project...
🌍 @blslancasteruni.bsky.social a UK Top 3 Biomedical Sciences Department
📌UK-based students only
⏱️Deadline 28th March
📮More info and to apply👇
www.findaphd.com/phds/project...
Reposted by Nik Copeland
Great to see our paper in @emboreports.org ! Collaboration between Prof Judy Coulson at Liverpool and ourselves @blslancasteruni.bsky.social. Many thanks to North West Cancer Research for funding! And congratulations to the team! www.embopress.org/doi/full/10....
February 19, 2025 at 8:40 PM
Great to see our paper in @emboreports.org ! Collaboration between Prof Judy Coulson at Liverpool and ourselves @blslancasteruni.bsky.social. Many thanks to North West Cancer Research for funding! And congratulations to the team! www.embopress.org/doi/full/10....