Nathan A. Tanner
@nathan-a-tanner.bsky.social
Associate Director, Applied Molecular Biology New England Biolabs
https://www.neb.com/en-us/research-labs/tanner-lab
https://www.neb.com/en-us/research-labs/tanner-lab
Reposted by Nathan A. Tanner
A big advance, folks, for off-the-shelf, universal, engineered (base-edited) T cells achieving complete response vs incurable leukemia in several patients
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
December 8, 2025 at 10:10 PM
A big advance, folks, for off-the-shelf, universal, engineered (base-edited) T cells achieving complete response vs incurable leukemia in several patients
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Dan Brown pitching his editor a new Christmas book
The bones of Santa have been leaking liquid for 1,700 years.
December 8, 2025 at 9:42 PM
Dan Brown pitching his editor a new Christmas book
Reposted by Nathan A. Tanner
The Married Scientists Torn Apart by a Covid Bioweapon Theory
www.nytimes.com
December 7, 2025 at 7:50 PM
objectively pro child death
Kennedy's zombie ACIP panel just voted to restrict hepatitis B vaccine for newborns. Experts say it will harm children for no reason. www.ms.now/news/rfk-cdc...
ACIP member Dr. Cody Meissner:
"'Do no harm' is a moral imperative. We are doing harm by changing this wording. And I vote no."
ACIP member Dr. Cody Meissner:
"'Do no harm' is a moral imperative. We are doing harm by changing this wording. And I vote no."
RFK Jr.’s CDC panel: No more hepatitis B vaccine for some newborns
The CDC's vaccine advisory panel, stocked with anti-vaccine activists and loyalists to RFK Jr., voted Friday to stop recommending a birth dose of vaccine.
www.ms.now
December 5, 2025 at 4:18 PM
objectively pro child death
Reposted by Nathan A. Tanner
Ready for a streamlined PCR & #DNAcleanup option? Our new Monarch Mag PCR & DNA Cleanup Kit (5 μg) (https://nebiolabs.com/4rPTMnE) uses a bind/wash/elute workflow for ssDNA and dsDNA with automation-friendly magnetic beads to eliminate the need for centrifugation or vacuum-based processing. 🦋
December 4, 2025 at 4:55 PM
Ready for a streamlined PCR & #DNAcleanup option? Our new Monarch Mag PCR & DNA Cleanup Kit (5 μg) (https://nebiolabs.com/4rPTMnE) uses a bind/wash/elute workflow for ssDNA and dsDNA with automation-friendly magnetic beads to eliminate the need for centrifugation or vacuum-based processing. 🦋
guess that’s why the talk I had to make this day turned out a little weird
December 4, 2025 at 3:48 AM
guess that’s why the talk I had to make this day turned out a little weird
Reposted by Nathan A. Tanner
Using a phage-inspired genetic screen and biochem, NEB, Harvard Medical School, and University of Illinois Urbana-Champaign researchers discovered OLD inactivates tRNAs by a completely novel mechanism: severing anticodon arms! https://nebiolabs.com/4rysTEk
#tRNA #PhageDefense
#tRNA #PhageDefense
OLD amputates the anticodon arm of tRNAs during P2–Lambda interference
Abstract. ATPase-coupled Toprim (Topoisomerase-primase) nucleases, known as Overcoming Lysogenization Defect (OLD) proteins, are crucial for diverse antiph
academic.oup.com
December 3, 2025 at 5:08 PM
Using a phage-inspired genetic screen and biochem, NEB, Harvard Medical School, and University of Illinois Urbana-Champaign researchers discovered OLD inactivates tRNAs by a completely novel mechanism: severing anticodon arms! https://nebiolabs.com/4rysTEk
#tRNA #PhageDefense
#tRNA #PhageDefense
pail offit has had it
December 1, 2025 at 3:16 AM
pail offit has had it
sad to see the Vols come to this but we deserve it
Slumber Party Martyrs (flipped), by Robin F. Williams, 2023
November 30, 2025 at 1:59 AM
sad to see the Vols come to this but we deserve it
Reposted by Nathan A. Tanner
HAPPY THANKSGIVIG - dashare.zone ADMIN
November 27, 2025 at 6:38 PM
HAPPY THANKSGIVIG - dashare.zone ADMIN
truly inspiring level of pettiness
Good morning to Brazilian reporter Manuela Borges, who’s been waiting eleven years for this petty moment. ❤️ 🇧🇷
November 26, 2025 at 3:38 PM
truly inspiring level of pettiness
Reposted by Nathan A. Tanner
a movie that takes place where you’re from
November 23, 2025 at 9:17 PM
a movie that takes place where you’re from
we use this in house for low-cost, high-throughput gene construction and are rolling out the tools for everyone to do it
#SynBio is often limited by how quickly & affordably researchers can synthesize custom DNA. Learn more about a web tool & workflow NEB scientists developed, bypassing outsourced DNA & enabling labs to produce sequence-verified constructs in just 4 days at lower cost. https://nebiolabs.com/48auZBo
Building Genes Faster and Cheaper with Decentralized Workflows | NEB
A new decentralized DNA synthesis workflow from NEB delivers sequence-confirmed genes in 4 days, cutting costs 3–5x and accelerating discovery.
www.neb.com
November 22, 2025 at 12:51 AM
we use this in house for low-cost, high-throughput gene construction and are rolling out the tools for everyone to do it
Very excited to see this come out, happy to have played a very small part
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
The A, B, C, D’s of replicative DNA polymerase fidelity: utilizing high-throughput single-molecule sequencing to understand the molecular basis for DNA polymerase accuracy
Abstract. DNA polymerases (DNAPs) are indispensable enzymes that play central roles in biology, by replicating and repairing genetic material, as well as i
academic.oup.com
November 21, 2025 at 7:03 PM
Very excited to see this come out, happy to have played a very small part
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Reposted by Nathan A. Tanner
#BREAKING: Former Harvard President Lawrence H. Summers will immediately leave his role as an instructor at Harvard while the University investigates his ties to child sex trafficker Jeffrey Epstein.
Dhruv T. Patel and Cam N. Srivastava report.
Dhruv T. Patel and Cam N. Srivastava report.
Summers Will Not Finish Semester of Teaching as Harvard Investigates Epstein Ties | News | The Harvard Crimson
Former Harvard President Lawrence H. Summers will immediately leave his role as an instructor at Harvard while the University investigates his ties to child sex trafficker Jeffrey E. Epstein.
www.thecrimson.com
November 20, 2025 at 12:30 AM
#BREAKING: Former Harvard President Lawrence H. Summers will immediately leave his role as an instructor at Harvard while the University investigates his ties to child sex trafficker Jeffrey Epstein.
Dhruv T. Patel and Cam N. Srivastava report.
Dhruv T. Patel and Cam N. Srivastava report.
unreal
This is completely disgusting. Today, the CDC updated their vaccine safety page. It now says:
“The claim "vaccines do not cause autism" is not an evidence-based claim because studies have not ruled out the possibility that infant vaccines cause autism”.
“The claim "vaccines do not cause autism" is not an evidence-based claim because studies have not ruled out the possibility that infant vaccines cause autism”.
November 20, 2025 at 3:13 AM
unreal
wonder how many people who have been to Jackson Hole, Aspen, and North Conway would say the latter is best
New Hampshire has the best ski town in America, according to USA Today readers trib.al/at0kFlT
New Hampshire has the best ski town in America, according to USA Today readers
North Conway is the best ski town in America, according to USA Today readers in the 2025 10Best Readers' Choice Awards.
trib.al
November 20, 2025 at 12:56 AM
wonder how many people who have been to Jackson Hole, Aspen, and North Conway would say the latter is best
March 5, my birthday, and now I’ll always think of this
oh my god you have to read this until the end www.telos.news/p/part-1-how...
Part 1: How I Found Out
Olivia had just returned from a reporting trip—at least that’s what she told me it was—and her Herschel backpack, the one with the flap that never quite closed properly, was tossed beside our bed, its...
www.telos.news
November 18, 2025 at 2:23 AM
March 5, my birthday, and now I’ll always think of this
Harvard response to all its involvements with Epstein has been woefully inadequate
When former Harvard President Lawrence H. Summers was pursuing a romantic relationship with a woman he described as a mentee, he turned to a longtime associate for guidance: Jeffrey E. Epstein.
Dhruv T. Patel and Cam N. Srivastava report.
Dhruv T. Patel and Cam N. Srivastava report.
As Summers Sought Clandestine Relationship With Woman He Called a Mentee, Epstein Was His ‘Wing Man’ | News | The Harvard Crimson
When former Harvard President Lawrence H. Summers was pursuing a romantic relationship with a woman he described as a mentee, he turned to a longtime associate for guidance: convicted sex offender…
www.thecrimson.com
November 17, 2025 at 2:37 AM
Harvard response to all its involvements with Epstein has been woefully inadequate
no it couldn’t
Anthropic CEO Dario Amodei thinks AI could help find cures for most cancers, prevent Alzheimer’s, and even double the human lifespan. cbsn.ws/4oRZ8Nm
November 17, 2025 at 1:32 AM
no it couldn’t
Reposted by Nathan A. Tanner
Elizabeth Holmes deserves so much worse. She was only ever convicted of defrauding her investors even though she also defrauded thousands of patients.
November 16, 2025 at 4:53 AM
Elizabeth Holmes deserves so much worse. She was only ever convicted of defrauding her investors even though she also defrauded thousands of patients.
A+ banner on this
November 16, 2025 at 1:22 AM
A+ banner on this