MMohammadi
@mmohammadi9812.bsky.social
Computational neuroscience researcher 🧠 | Always keen to connect with fellow researchers
Reposted by MMohammadi
The "Computational Theory of Mind" has become the modern secular religion, promising that if we just find the right algorithm, we can replicate intelligence.
www.ocrampal.com/computation-...
#philosophy #science #AI #intelligence #cogsci #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
www.ocrampal.com/computation-...
#philosophy #science #AI #intelligence #cogsci #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
Computation is not the right framework to comprehend the concept of life and intelligence
We live in a computational age. When we want to formalize our thoughts—to express ideas precisely, to build models of intelligence, to create systems that reason—we almost instinctively reach for comp...
www.ocrampal.com
December 25, 2025 at 4:25 PM
The "Computational Theory of Mind" has become the modern secular religion, promising that if we just find the right algorithm, we can replicate intelligence.
www.ocrampal.com/computation-...
#philosophy #science #AI #intelligence #cogsci #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
www.ocrampal.com/computation-...
#philosophy #science #AI #intelligence #cogsci #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
Reposted by MMohammadi
PLEASE REPOST AND SHARE WITH ANY RESEARCHERS AIMING TO COME (BACK) TO CANADA
Background on the program: www.theglobeandmail.com/canada/educa...
#psychjobs
#neurojobs
#neuroskyence
Background on the program: www.theglobeandmail.com/canada/educa...
#psychjobs
#neurojobs
#neuroskyence
December 22, 2025 at 3:41 PM
PLEASE REPOST AND SHARE WITH ANY RESEARCHERS AIMING TO COME (BACK) TO CANADA
Background on the program: www.theglobeandmail.com/canada/educa...
#psychjobs
#neurojobs
#neuroskyence
Background on the program: www.theglobeandmail.com/canada/educa...
#psychjobs
#neurojobs
#neuroskyence
Reposted by MMohammadi
𝗢𝗻 𝗯𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗮𝗻𝗱 𝗮𝗿𝘁𝗶𝗳𝗶𝗰𝗶𝗮𝗹 𝗰𝗼𝗻𝘀𝗰𝗶𝗼𝘂𝘀𝗻𝗲𝘀𝘀: 𝗔 𝗰𝗮𝘀𝗲 𝗳𝗼𝗿 𝗯𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹𝗶𝘀𝗺
Excellent paper discussing how considering biology is important to understand consciousness.
Really enjoyed this one.
doi.org/10.1016/j.ne...
#neuroskyence
Excellent paper discussing how considering biology is important to understand consciousness.
Really enjoyed this one.
doi.org/10.1016/j.ne...
#neuroskyence
December 21, 2025 at 4:50 PM
𝗢𝗻 𝗯𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗮𝗻𝗱 𝗮𝗿𝘁𝗶𝗳𝗶𝗰𝗶𝗮𝗹 𝗰𝗼𝗻𝘀𝗰𝗶𝗼𝘂𝘀𝗻𝗲𝘀𝘀: 𝗔 𝗰𝗮𝘀𝗲 𝗳𝗼𝗿 𝗯𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹𝗶𝘀𝗺
Excellent paper discussing how considering biology is important to understand consciousness.
Really enjoyed this one.
doi.org/10.1016/j.ne...
#neuroskyence
Excellent paper discussing how considering biology is important to understand consciousness.
Really enjoyed this one.
doi.org/10.1016/j.ne...
#neuroskyence
Reposted by MMohammadi
Are axon and dendrite development indeed driven by separate mechanisms? By building a data-integrated biophysical model across developmental stages, we identified slowdown of microtubule retrograde flow (MT-RF) as unifying mechanism for both axon and dendrite development doi.org/10.64898/202... 🧪 🧠📈
December 19, 2025 at 4:25 PM
Are axon and dendrite development indeed driven by separate mechanisms? By building a data-integrated biophysical model across developmental stages, we identified slowdown of microtubule retrograde flow (MT-RF) as unifying mechanism for both axon and dendrite development doi.org/10.64898/202... 🧪 🧠📈
Reposted by MMohammadi
are better-performing face recognition models more human-like? turns out: NO
in terms of how we see/treat different faces as similar/different to each other, there seems to be tradeoff: better models are LESS human-like
so they already work in some 'alien' ways...
osf.io/preprints/ps...
🧠📈🧠🤖🧠💻
in terms of how we see/treat different faces as similar/different to each other, there seems to be tradeoff: better models are LESS human-like
so they already work in some 'alien' ways...
osf.io/preprints/ps...
🧠📈🧠🤖🧠💻
OSF
osf.io
December 10, 2025 at 12:34 AM
are better-performing face recognition models more human-like? turns out: NO
in terms of how we see/treat different faces as similar/different to each other, there seems to be tradeoff: better models are LESS human-like
so they already work in some 'alien' ways...
osf.io/preprints/ps...
🧠📈🧠🤖🧠💻
in terms of how we see/treat different faces as similar/different to each other, there seems to be tradeoff: better models are LESS human-like
so they already work in some 'alien' ways...
osf.io/preprints/ps...
🧠📈🧠🤖🧠💻
Reposted by MMohammadi
Out now in @ebiomedicine.bsky.social 🚨.
Hunger often affects our mood, but is this a conscious or a subconscious process? Using continuous glucose monitoring, we show that differences in mood are driven by hunger ratings, not just glucose. #neuroskyence 🩺
www.thelancet.com/journals/EBI...
Hunger often affects our mood, but is this a conscious or a subconscious process? Using continuous glucose monitoring, we show that differences in mood are driven by hunger ratings, not just glucose. #neuroskyence 🩺
www.thelancet.com/journals/EBI...
December 8, 2025 at 1:33 PM
Out now in @ebiomedicine.bsky.social 🚨.
Hunger often affects our mood, but is this a conscious or a subconscious process? Using continuous glucose monitoring, we show that differences in mood are driven by hunger ratings, not just glucose. #neuroskyence 🩺
www.thelancet.com/journals/EBI...
Hunger often affects our mood, but is this a conscious or a subconscious process? Using continuous glucose monitoring, we show that differences in mood are driven by hunger ratings, not just glucose. #neuroskyence 🩺
www.thelancet.com/journals/EBI...
Reposted by MMohammadi
Missed our basal ganglia cell types webinar? Watch the recording over on our YouTube channel!
🧠📈 https://www.youtube.com/watch?v=nlZ0gp0eshc
🧠📈 https://www.youtube.com/watch?v=nlZ0gp0eshc
Mapping the Cellular Architecture of the Mammalian Basal Ganglia
YouTube video by Allen Institute
www.youtube.com
December 8, 2025 at 9:00 PM
Missed our basal ganglia cell types webinar? Watch the recording over on our YouTube channel!
🧠📈 https://www.youtube.com/watch?v=nlZ0gp0eshc
🧠📈 https://www.youtube.com/watch?v=nlZ0gp0eshc
Reposted by MMohammadi
Brain’s ‘plumbing’ inspires new Alzheimer’s strategies—and controversial surgeries science.org/content/arti... by @science.org
#Alzheimers #dementia #science #neuroscience #NeuroSkyence
#Alzheimers #dementia #science #neuroscience #NeuroSkyence
Brain’s ‘plumbing’ inspires new Alzheimer’s strategies—and controversial surgeries
Animal studies support idea that boosting fluid clearance could blunt neurological disorders
science.org
December 8, 2025 at 10:01 PM
Brain’s ‘plumbing’ inspires new Alzheimer’s strategies—and controversial surgeries science.org/content/arti... by @science.org
#Alzheimers #dementia #science #neuroscience #NeuroSkyence
#Alzheimers #dementia #science #neuroscience #NeuroSkyence
Reposted by MMohammadi
Reminder to submit Symposia & Workshops
for #epc-apcv-2026 by 31 Jan 2026!
Also announcing keynotes:
- Hakwan Lau (IBS, South Korea
- Elaine Reese (Uni of Otago, NZ
- Corey Wadsley (Uni of Auckland, NZ)
visualneuroscience.auckland.ac.nz/epc-apcv-2026
#psychscisky #visionscience #neuroskyence
for #epc-apcv-2026 by 31 Jan 2026!
Also announcing keynotes:
- Hakwan Lau (IBS, South Korea
- Elaine Reese (Uni of Otago, NZ
- Corey Wadsley (Uni of Auckland, NZ)
visualneuroscience.auckland.ac.nz/epc-apcv-2026
#psychscisky #visionscience #neuroskyence
December 8, 2025 at 11:33 PM
Reminder to submit Symposia & Workshops
for #epc-apcv-2026 by 31 Jan 2026!
Also announcing keynotes:
- Hakwan Lau (IBS, South Korea
- Elaine Reese (Uni of Otago, NZ
- Corey Wadsley (Uni of Auckland, NZ)
visualneuroscience.auckland.ac.nz/epc-apcv-2026
#psychscisky #visionscience #neuroskyence
for #epc-apcv-2026 by 31 Jan 2026!
Also announcing keynotes:
- Hakwan Lau (IBS, South Korea
- Elaine Reese (Uni of Otago, NZ
- Corey Wadsley (Uni of Auckland, NZ)
visualneuroscience.auckland.ac.nz/epc-apcv-2026
#psychscisky #visionscience #neuroskyence
Reposted by MMohammadi
December 3, 2025 at 6:10 PM
Reposted by MMohammadi
𝗕𝗼𝘁𝘁𝗼𝗺 𝘂𝗽 𝗮𝗻𝗱/𝗼𝗿 𝘁𝗼𝗽-𝗱𝗼𝘄𝗻 𝗻𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲
Discussion by @sandervanbree.bsky.social and Poeppel on paper by@frosas.bsky.socialetal
Would have thought entangled brain framework more on side of holism but also raises issue of irreducible interactive complexity
#neuroskyence
www.nature.com/articles/s41...
Discussion by @sandervanbree.bsky.social and Poeppel on paper by@frosas.bsky.socialetal
Would have thought entangled brain framework more on side of holism but also raises issue of irreducible interactive complexity
#neuroskyence
www.nature.com/articles/s41...
December 4, 2025 at 6:50 PM
𝗕𝗼𝘁𝘁𝗼𝗺 𝘂𝗽 𝗮𝗻𝗱/𝗼𝗿 𝘁𝗼𝗽-𝗱𝗼𝘄𝗻 𝗻𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲
Discussion by @sandervanbree.bsky.social and Poeppel on paper by@frosas.bsky.socialetal
Would have thought entangled brain framework more on side of holism but also raises issue of irreducible interactive complexity
#neuroskyence
www.nature.com/articles/s41...
Discussion by @sandervanbree.bsky.social and Poeppel on paper by@frosas.bsky.socialetal
Would have thought entangled brain framework more on side of holism but also raises issue of irreducible interactive complexity
#neuroskyence
www.nature.com/articles/s41...
Reposted by MMohammadi
**How distributed is the brain-wide network that is recruited
for cognition?**
That goes to the top of the list!
#neuroskyence
doi.org/10.1038/s415...
for cognition?**
That goes to the top of the list!
#neuroskyence
doi.org/10.1038/s415...
December 5, 2025 at 6:51 PM
**How distributed is the brain-wide network that is recruited
for cognition?**
That goes to the top of the list!
#neuroskyence
doi.org/10.1038/s415...
for cognition?**
That goes to the top of the list!
#neuroskyence
doi.org/10.1038/s415...
Reposted by MMohammadi
33 neuroscience researchers from across the world shared how their labs our funded, providing insight into the current state of funding and how that might shift.
By @claudia-lopez.bsky.social
#neuroskyence #StateOfNeuroscience
www.thetransmitter.org/funding/whic...
By @claudia-lopez.bsky.social
#neuroskyence #StateOfNeuroscience
www.thetransmitter.org/funding/whic...
Survey: Which sources fund your neuroscience research?
Government sources are the main contributors to neuroscience labs, but funding breakdown varies across labs, career stages and neuroscience subfields.
www.thetransmitter.org
December 2, 2025 at 6:05 PM
33 neuroscience researchers from across the world shared how their labs our funded, providing insight into the current state of funding and how that might shift.
By @claudia-lopez.bsky.social
#neuroskyence #StateOfNeuroscience
www.thetransmitter.org/funding/whic...
By @claudia-lopez.bsky.social
#neuroskyence #StateOfNeuroscience
www.thetransmitter.org/funding/whic...
Reposted by MMohammadi
I had the pleasure of chatting with HOW DO WE MANAGE podcast about the nature of our shared reality — and to talk about my book with @phdcomics.com www.youtube.com/watch?v=vubq... #neuroscience #brainhealth #science #neuroskyence
How Your Brain Creates (and Tricks) Your Reality | How Do We Manage?
YouTube video by How Do We Manage? Podcast
www.youtube.com
December 2, 2025 at 6:57 PM
I had the pleasure of chatting with HOW DO WE MANAGE podcast about the nature of our shared reality — and to talk about my book with @phdcomics.com www.youtube.com/watch?v=vubq... #neuroscience #brainhealth #science #neuroskyence
Reposted by MMohammadi
Enough #Bayesplaining. It's time to start "deriving."
We're unifying physics and neuroscience from first principles (yes, really).
Come argue with me tomorrow @ 11 AM.
@neuripsconf.bsky.social
🧠🤖🧠📈
We're unifying physics and neuroscience from first principles (yes, really).
Come argue with me tomorrow @ 11 AM.
@neuripsconf.bsky.social
🧠🤖🧠📈
December 3, 2025 at 3:23 AM
Enough #Bayesplaining. It's time to start "deriving."
We're unifying physics and neuroscience from first principles (yes, really).
Come argue with me tomorrow @ 11 AM.
@neuripsconf.bsky.social
🧠🤖🧠📈
We're unifying physics and neuroscience from first principles (yes, really).
Come argue with me tomorrow @ 11 AM.
@neuripsconf.bsky.social
🧠🤖🧠📈
Reposted by MMohammadi
𝗪𝗵𝗮𝘁 𝗮𝗿𝗲 𝗯𝗿𝗮𝗶𝗻 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀?
Do they even exist...?
Join @lucinauddin.bsky.social who will present, followed by discussion in the Neuroscience & Philosophy Salon.
Open to all.
Date: Dec 9, 12pm EST-US
Register: umd.zoom.us/meeting/regi... (you need a zoom account which is free)
#neuroskyence
Do they even exist...?
Join @lucinauddin.bsky.social who will present, followed by discussion in the Neuroscience & Philosophy Salon.
Open to all.
Date: Dec 9, 12pm EST-US
Register: umd.zoom.us/meeting/regi... (you need a zoom account which is free)
#neuroskyence
Welcome! You are invited to join a meeting: NeuroPhilo Salon. After registering, you will receive a confirmation email about joining the meeting.
Welcome! You are invited to join a meeting: NeuroPhilo Salon. After registering, you will receive a confirmation email about joining the meeting.
umd.zoom.us
November 29, 2025 at 5:14 PM
𝗪𝗵𝗮𝘁 𝗮𝗿𝗲 𝗯𝗿𝗮𝗶𝗻 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀?
Do they even exist...?
Join @lucinauddin.bsky.social who will present, followed by discussion in the Neuroscience & Philosophy Salon.
Open to all.
Date: Dec 9, 12pm EST-US
Register: umd.zoom.us/meeting/regi... (you need a zoom account which is free)
#neuroskyence
Do they even exist...?
Join @lucinauddin.bsky.social who will present, followed by discussion in the Neuroscience & Philosophy Salon.
Open to all.
Date: Dec 9, 12pm EST-US
Register: umd.zoom.us/meeting/regi... (you need a zoom account which is free)
#neuroskyence
Reposted by MMohammadi
I will be at @neuripsconf.bsky.social Dec 2-8 to present our "Brain-like Variational Inference" paper 👇
Let's connect if you enjoy first-principles thinking and brain-inspired AI 🧠 🤖
Poster info:
📅 Wed, Dec 3, 11 AM — 2 PM
📍Exhibit Hall C,D,E #500
🔗 neurips.cc/virtual/2025...
🧵[1/4]
🧠🤖🧠📈
Let's connect if you enjoy first-principles thinking and brain-inspired AI 🧠 🤖
Poster info:
📅 Wed, Dec 3, 11 AM — 2 PM
📍Exhibit Hall C,D,E #500
🔗 neurips.cc/virtual/2025...
🧵[1/4]
🧠🤖🧠📈
November 30, 2025 at 5:49 AM
I will be at @neuripsconf.bsky.social Dec 2-8 to present our "Brain-like Variational Inference" paper 👇
Let's connect if you enjoy first-principles thinking and brain-inspired AI 🧠 🤖
Poster info:
📅 Wed, Dec 3, 11 AM — 2 PM
📍Exhibit Hall C,D,E #500
🔗 neurips.cc/virtual/2025...
🧵[1/4]
🧠🤖🧠📈
Let's connect if you enjoy first-principles thinking and brain-inspired AI 🧠 🤖
Poster info:
📅 Wed, Dec 3, 11 AM — 2 PM
📍Exhibit Hall C,D,E #500
🔗 neurips.cc/virtual/2025...
🧵[1/4]
🧠🤖🧠📈
Reposted by MMohammadi
*13th MindBrainBody Symposium*
📆 Mar 9-11, 2026
🏠 #Berlin & virtual
(deadline: Jan 8, 2026)
Keynotes:
- @ulrikebingel.bsky.social
- Karl Friston (online)
- @tinalonsdorf.bsky.social
- Sonja Kotz
- Julian Thayer
...& so much more: prizes, posters, talks, food, drinks, encounters.
Let's meet!
📆 Mar 9-11, 2026
🏠 #Berlin & virtual
(deadline: Jan 8, 2026)
Keynotes:
- @ulrikebingel.bsky.social
- Karl Friston (online)
- @tinalonsdorf.bsky.social
- Sonja Kotz
- Julian Thayer
...& so much more: prizes, posters, talks, food, drinks, encounters.
Let's meet!
December 1, 2025 at 7:28 AM
*13th MindBrainBody Symposium*
📆 Mar 9-11, 2026
🏠 #Berlin & virtual
(deadline: Jan 8, 2026)
Keynotes:
- @ulrikebingel.bsky.social
- Karl Friston (online)
- @tinalonsdorf.bsky.social
- Sonja Kotz
- Julian Thayer
...& so much more: prizes, posters, talks, food, drinks, encounters.
Let's meet!
📆 Mar 9-11, 2026
🏠 #Berlin & virtual
(deadline: Jan 8, 2026)
Keynotes:
- @ulrikebingel.bsky.social
- Karl Friston (online)
- @tinalonsdorf.bsky.social
- Sonja Kotz
- Julian Thayer
...& so much more: prizes, posters, talks, food, drinks, encounters.
Let's meet!
Reposted by MMohammadi
@braininspired.bsky.social talks with Henk de Regt about what it means for both humans and artificial-intelligence agents to “understand,” and how to assess this understanding.
www.thetransmitter.org/brain-inspir...
#neuroskyence
www.thetransmitter.org/brain-inspir...
#neuroskyence
Does AI understand what it produces? Henk de Regt explores how we might assess understanding in machines and humans
Building on his philosophy of how scientists understand what they work on, de Regt is extending his approach to test understanding in machines.
www.thetransmitter.org
November 19, 2025 at 3:04 PM
@braininspired.bsky.social talks with Henk de Regt about what it means for both humans and artificial-intelligence agents to “understand,” and how to assess this understanding.
www.thetransmitter.org/brain-inspir...
#neuroskyence
www.thetransmitter.org/brain-inspir...
#neuroskyence
Reposted by MMohammadi
Why we create paradoxes when we ask the wrong questions?
www.ocrampal.com/how-asking-t...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
www.ocrampal.com/how-asking-t...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
How Asking the Wrong Question Creates Mysteries That Don't Exist
What if I told you that the deepest mysteries plaguing human knowledge—consciousness emerging from matter, the mind-body problem, infinite regress, self-reference paradoxes—aren't profound features of...
www.ocrampal.com
November 12, 2025 at 1:16 PM
Why we create paradoxes when we ask the wrong questions?
www.ocrampal.com/how-asking-t...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
www.ocrampal.com/how-asking-t...
#philosophy #science #psychology #AI #intelligence #physics #biology #philmind #philsci #philsky #philpsy #neurosky #neuroskyence
Reposted by MMohammadi
Decisions under uncertainty are a coordinated action of PFC, pre/motor, BG, and thalamus.
This model tries to explain decision impairments by hyperactive D2 receptors
We can clarify the paper by building a mouse with schizophrenia.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
This model tries to explain decision impairments by hyperactive D2 receptors
We can clarify the paper by building a mouse with schizophrenia.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
November 13, 2025 at 11:58 AM
Decisions under uncertainty are a coordinated action of PFC, pre/motor, BG, and thalamus.
This model tries to explain decision impairments by hyperactive D2 receptors
We can clarify the paper by building a mouse with schizophrenia.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
This model tries to explain decision impairments by hyperactive D2 receptors
We can clarify the paper by building a mouse with schizophrenia.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
Reposted by MMohammadi
Many of our big insights into brain function come from trying to mimic it, writes @timothyoleary.bsky.social. This lesson should guide how we organize research programs.
www.thetransmitter.org/systems-neur...
#neuroskyence
www.thetransmitter.org/systems-neur...
#neuroskyence
Neuroscience needs engineers—for more reasons than you think
Adopting an engineering mindset will help the field focus its research priorities.
www.thetransmitter.org
November 3, 2025 at 2:22 PM
Many of our big insights into brain function come from trying to mimic it, writes @timothyoleary.bsky.social. This lesson should guide how we organize research programs.
www.thetransmitter.org/systems-neur...
#neuroskyence
www.thetransmitter.org/systems-neur...
#neuroskyence
Reposted by MMohammadi
Glia gang, this is for you!
In this video by our #ElectronMicroscopy team, shows a pyramidal neuron (PyC) surrounded by 8 glia brain cells – 5 microglia (MG) and 3 oligodendrocyte progenitor cells (OPC).
🧠📈 http://microns-explorer.org
In this video by our #ElectronMicroscopy team, shows a pyramidal neuron (PyC) surrounded by 8 glia brain cells – 5 microglia (MG) and 3 oligodendrocyte progenitor cells (OPC).
🧠📈 http://microns-explorer.org
November 3, 2025 at 3:47 PM
Glia gang, this is for you!
In this video by our #ElectronMicroscopy team, shows a pyramidal neuron (PyC) surrounded by 8 glia brain cells – 5 microglia (MG) and 3 oligodendrocyte progenitor cells (OPC).
🧠📈 http://microns-explorer.org
In this video by our #ElectronMicroscopy team, shows a pyramidal neuron (PyC) surrounded by 8 glia brain cells – 5 microglia (MG) and 3 oligodendrocyte progenitor cells (OPC).
🧠📈 http://microns-explorer.org
Reposted by MMohammadi
This new miBrain model from MIT has it all:
🧠 Neurons, microglia, oligodendroglia, astrocytes, pericytes, & brain microvascular endothelial cells
⚙️ Key features & functions of the human brain
👩👦 Specificity to individual donors
🧬 Customizability via gene editing
📈 Scalability for large projects
🧠 Neurons, microglia, oligodendroglia, astrocytes, pericytes, & brain microvascular endothelial cells
⚙️ Key features & functions of the human brain
👩👦 Specificity to individual donors
🧬 Customizability via gene editing
📈 Scalability for large projects
![Image from the MIT Picower article, "MIT invents human brain model with six major cell types to enable personalized disease research, drug discovery" with the following caption: “Cyan staining shows each of the six major cell types [pericytes, astrocytes, endothelial cells, neurons, oligodendrocytes, and microglia] integrated in a miBrain culture.” The original image appeared in Figure 1 of the PNAS article, “Engineered 3D immuno-glial-neurovascular human miBrain model” (10.1073/pnas.2511596122) by Stanton et al.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:in2pnzujy66a7qnesoxha6ar/bafkreig4udiootxzzdxay4vwclppbwedfythnr36dzzoavgbrzvz2m54va@jpeg)
November 3, 2025 at 7:28 PM
This new miBrain model from MIT has it all:
🧠 Neurons, microglia, oligodendroglia, astrocytes, pericytes, & brain microvascular endothelial cells
⚙️ Key features & functions of the human brain
👩👦 Specificity to individual donors
🧬 Customizability via gene editing
📈 Scalability for large projects
🧠 Neurons, microglia, oligodendroglia, astrocytes, pericytes, & brain microvascular endothelial cells
⚙️ Key features & functions of the human brain
👩👦 Specificity to individual donors
🧬 Customizability via gene editing
📈 Scalability for large projects
Reposted by MMohammadi
Spatial reasoning has never been a strong point for LLMs, and all the benchmarks here involve some kind of spatial element.
Not sure how surprising these findings are, especially since major LLM strengths (like coding) aren’t included in this analysis.
Not sure how surprising these findings are, especially since major LLM strengths (like coding) aren’t included in this analysis.
There's a lot of big news today/this week, but Apple just dropped a nuke of a paper about LLMs & LRMs, specially around "high-complexity tasks where both models experience complete collapse." This is the biggest sign yet that if AI ever lives up the hype, it won't be via those approaches:
The Illusion of Thinking: Understanding the Strengths and Limitations of Reasoning Models via the Lens of Problem Complexity
Recent generations of frontier language models have introduced Large Reasoning Models
(LRMs) that generate detailed thinking processes…
machinelearning.apple.com
June 9, 2025 at 3:39 PM
Spatial reasoning has never been a strong point for LLMs, and all the benchmarks here involve some kind of spatial element.
Not sure how surprising these findings are, especially since major LLM strengths (like coding) aren’t included in this analysis.
Not sure how surprising these findings are, especially since major LLM strengths (like coding) aren’t included in this analysis.