Ian Kremer
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leadcoalition.bsky.social
Ian Kremer
@leadcoalition.bsky.social
17K followers 8.2K following 1.6K posts
Executive Director at the LEAD Coalition (a diverse, national coalition working to overcome #Alzheimers disease and other forms of #dementia). @umichlaw.bsky.social and WashU alum.

You may have known me as @LEAD_Coalition on the bird site
Posts Replies Media Videos
leadcoalition.bsky.social
Looking out for your community isn't charity. It is fundamental decency and an understanding about what it means to live in a humane society.

#SNAP #shutdown #hunger #dignity
shamalamadingbong.bsky.social Shama Lama Ding Bong @shamalamadingbong.bsky.social · 2d
Europe doing it right….
November 10, 2025 at 10:38 PM
leadcoalition.bsky.social
The shutdown isn't over yet, so there's still time to share this starter pack from sister @mrsdeborahlynn.bsky.social (not to preclude anyone from giving Members of Congress an earful about various issues essential to the wellbeing of the most vulnerable among us)!
mrsdeborahlynn.bsky.social Deborah Lynn @mrsdeborahlynn.bsky.social · 17h
Congress shouldn’t be paid during a government shutdown

go.bsky.app/36UAXEe
November 10, 2025 at 10:35 PM
leadcoalition.bsky.social
This may feel like a week that'll have at least two Mondays, so fittingly, our sister @judithbolyard.bsky.social has is sharing a double starter pack!
judithbolyard.bsky.social judithbolyard.bsky.social @judithbolyard.bsky.social · 18h
Thank you for Support, Laughter, and Kindness
BLUE WAVE STRONG! big hugz 💜

Monday Super Blues 29 - DOUBLE PACK #103
go.bsky.app/ViMxTyD

Monday Super Blues 30 - DOUBLE PACK #104
go.bsky.app/4o9vw4L
November 10, 2025 at 10:32 PM
leadcoalition.bsky.social
I'm sharing this @filosia.bsky.social starter pack a day late, but it gets better with age. :-)
filosia.bsky.social Meidas Sassy™ 🐬 @filosia.bsky.social · 1d
✨ SUPER SUNDAY PARTY ✨

Most of you already expect my SP on Sundays. #34 is once again packed with fierce resisters! Give them a follow. They inform you, fight for democracy and many will follow you back.

Keep #StrongerTogether, numbers are working, last week showed 🫂

Repost 🔄🙏🏼🌹

#StopTheMadness 👊🏼
November 10, 2025 at 10:29 PM
leadcoalition.bsky.social
Enormously important news, not least of all in the context of people being able to make health care, financial, legal, and other decisions for their spouses who have dementia. www.cnn.com/2025/11/10/p...

#Alzheimers #dementia #LGBTQ+ #SCOTUS #law #LoveIsLove
Supreme Court declines to revisit landmark same-sex marriage precedent | CNN Politics
The Supreme Court on Monday declined an opportunity to overturn its landmark precedent recognizing a constitutional right to same-sex marriage, tossing aside an appeal that had roiled LGBTQ advocates ...
www.cnn.com
November 10, 2025 at 8:03 PM
leadcoalition.bsky.social
When caregiving for a loved one, making self-care a priority can feel impossible. For your own wellbeing and that of the person you love, it is a practical necessity and a key to endurance.

#Alzheimers #dementia #mentalhealth #quote
"There will be days you need to pause and stand still, so that you have what it takes to keep going tomorrow!"
November 10, 2025 at 5:29 PM
leadcoalition.bsky.social
In these painful and chaotic times, it is more important than ever to love the most vulnerable among us.

(image via @notwithoutafight24.bsky.social)
image of happy children holding hands in a sunshine filled meadow of flowers with the lyrics "Come on people now, smile on your brother, everybody get together, try to love one another right now."
November 10, 2025 at 4:14 PM
leadcoalition.bsky.social
Love this starter pack from sister @boldsea.bsky.social!
November 10, 2025 at 4:10 PM
leadcoalition.bsky.social
Check out this starter pack from our friend @sentenne.bsky.social! go.bsky.app/3azis6g
November 10, 2025 at 4:09 PM
leadcoalition.bsky.social
How a childhood virus can contribute to dementia later and what you can do wapo.st/4qQVFzK

#Alzheimers #dementia #chickenpox #shingles #vaccines
How a childhood virus can contribute to dementia later and what you can do
A new study suggests that the shingles vaccine may help prevent dementia by reducing the risk of varicella-zoster virus reactivation.
wapo.st
November 10, 2025 at 1:22 PM
leadcoalition.bsky.social
Even a few thousand steps a day can reduce your risk of Alzheimer’s – new study theconversation.com/even-a-few-t...

#Alzheimers #dementia #exercise #fitness #health #wellness
Even a few thousand steps a day can reduce your risk of Alzheimer’s – new study
Even modest amounts of walking – as few as 3,000 steps a day – may help protect against Alzheimer’s by reducing harmful tau proteins in the brain.
theconversation.com
November 10, 2025 at 1:24 AM
leadcoalition.bsky.social
Extended interview: Bill Gates on Alzheimer's www.cbsnews.com/video/extend... via @cbsnews.com

#Alzheimers #dementia #science #EndAlz
Extended interview: Bill Gates on Alzheimer's research
In this web exclusive, Microsoft co-founder and philanthropist Bill Gates talks with CBS News chief medical correspondent Dr. Jon LaPook about backing research into Alzheimer's, a disease which affect...
www.cbsnews.com
November 10, 2025 at 12:08 AM
leadcoalition.bsky.social
Please send some love to these folks by sharing the "With a Little Help From My Friends..." Starter Pack #2. Together, we can boost them toward (and past) 20,000 BlueSky followers and build the movement!
November 9, 2025 at 9:13 PM
leadcoalition.bsky.social
Real patriots hold sacred the American motto "e pluribus unum" ("out of many, one"). We're all in this together. Those who don't lift us all up, tear us all down.
heatherturiello.bsky.social Heather Turiello @heatherturiello.bsky.social · 5d
I get so sick of people using the word wrong. Just stop. Get a dictionary. Go for a walk. Just calm down.
November 9, 2025 at 7:51 PM
leadcoalition.bsky.social
Please share sister the "Get LOUDER!" Starter Pack from our sister @maryosteen.bsky.social!
maryosteen.bsky.social Love, Ms.O 💋 @maryosteen.bsky.social · 2d
📣💥 Let’s Get Louder 💥📣 Please enjoy my latest Starter Pack of friends that are true #Resisters defending democracy in their own unique, invaluable ways. Vet, Follow and Repost to build our #Resistance. (In case I forgot someone, I’m hoping to drop another Pack soon) Love, MsO 💋

go.bsky.app/WipaYC
November 9, 2025 at 7:46 PM
leadcoalition.bsky.social
Small acts of kindness measure our caregiving.

#Alzheimers #dementia #caregiving #kindess #quote
"A person with dementia deserves to be treated with dignity and respect. This is measured in little acts of kindness. Ask him to help with daily activities. Help him develop ways to compensate for changing abilities. Be patient when he takes more time than usual. Offer appreciation and praise for the job he is doing. Kindness is a language everyone speaks... and everyone understands." ~ MaryAnne
November 9, 2025 at 6:41 PM
leadcoalition.bsky.social
How family caregivers can obtain medical equipment for in-home care www.inforum.com/health/bursa... by @mindingourelders.bsky.social

#Alzheimers #dementia #caregiving
A home health aide helping a woman use a walker to rise up off a couch
November 9, 2025 at 4:38 PM
leadcoalition.bsky.social
Music Brings My Grandmother Back beingpatient.com/music-brings... via @beingpatient.bsky.social

#Alzheimers #dementia #music #happiness
Music Brings My Grandmother Back
Alex Billingsley writes about how listening to music with her grandmother became a source of connection for them.
beingpatient.com
November 9, 2025 at 3:06 PM
leadcoalition.bsky.social
National 211 hotline calls for food assistance quadrupled in a matter of days, a magnitude typically seen during disasters www.cnn.com/2025/11/08/h...

#SNAP #shutdown #hunger
National 211 hotline calls for food assistance quadrupled in a matter of days, a magnitude typically seen during disasters | CNN
Between January and mid-October 2025, calls to local 211 helplines from people seeking food pantries in their community held steady at nearly 1,000 calls per day.
www.cnn.com
November 9, 2025 at 2:34 AM
leadcoalition.bsky.social
Neurometabolic and vascular dysfunction as an early diagnostic for Alzheimer's disease and related dementias alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

#Alzheimers #dementia #science #neuroscience #NeuroSkyence
Neurovascular and metabolic changes across the AD spectrum, MVD pattern, and polar coordinates representation. A, The normal metabolic state continuum in healthy individuals is depicted by the black line. In contrast, the metabolic state across AD is represented by the orange line, illustrating the metabolic alterations observed throughout the disease's various phases, as proposed by the metabolic reprogramming theory. The red line represents the progression of perfusion across the disease, demonstrating how metabolism and perfusion become dysregulated until they eventually fail. During the hypermetabolic phase of the disease, oxidative phosphorylation undergoes upregulation as a compensatory response, leading to progressively oxidative damage. Furthermore, it is suggested that astrocytosis signaling precedes the onset of cognitive decline. B, Neurovascular and metabolic dysregulation were assessed by projecting the z score SUVR for each brain region onto Cartesian space. The x axis represents the z score changes in cerebral perfusion derived from CBF maps, while the y axis represents the z score change in glucose uptake derived from FDG. Brain regions toward the center of the plane are likely functioning at a normal level. A brain region is considered coupled if both signals are in the same direction (Cartesian quadrants 1 and 3) and uncoupled if they are opposite (Cartesian quadrants 2 and 4). We hypothesize the existence of a regional disease pathway (MVD pattern) that maps the disease progression and can accurately discern the MVD changes, which is: Type 1 Uncoupling → Type 2 Uncoupling → Prodromal → Neurometabolic-vascular Failure. C, Alternatively, Cartesian space readouts can be transformed into polar coordinates to visualize disease progression while preserving the MVD state. The distance from the origin represents the magnitude of the change, while the angle indicates the deviation of the change.
November 9, 2025 at 12:59 AM
leadcoalition.bsky.social
Heartbreaking.
November 8, 2025 at 8:31 PM
leadcoalition.bsky.social
People living with dementia need and deserve love just as much as anyone else.

#Alzheimers #dementia #happiness #kindness #quote
"With love comes a softening, a gentleness, a kindness, a joy." ~ Laura Jaworski
November 8, 2025 at 5:52 PM
leadcoalition.bsky.social
If you've ever wondered why some people are so anxious to undermine arts education in public schools and to censor arts institutions...
"The true purpose of arts education is not necessarily to create more professional dancers and artists. [It's] to create more complete human beings who are critical thinkers, who have curious minds, who can lead productive lives."
November 8, 2025 at 4:46 PM
leadcoalition.bsky.social
Genetic Drivers for Cerebrovascular and Alzheimer’s Diseases are Distinct www.alzforum.org/news/researc...

#Alzheimers #dementia #genetics #epigenomics #neuroscience #NeuroSkyence
(A) Schematic of nuclei isolation and epigenomic profiling of brain cell types from resected and post-mortem cortical samples. (B) UCSC genome browser visualization of H3K27ac and H3K4me3 CUT&Tag at cell-type-specific marker gene loci. (C) EWCE analysis of cell-type-specific promoters for resected and post-mortem brain cell types and for primary pericytes and BECs in brain single-cell gene expression.5∗Benjamini-Hochberg-corrected q < 0.05; ∗∗Benjamini-Hochberg-corrected q = 0. (D) CAMERA analysis of cell-type annotations from brain single-cell gene expression5 using differential promoters from resected and post-mortem brain cell types.
November 8, 2025 at 3:31 PM
Reposted by Ian Kremer
mlipsitt.bsky.social
One one of many personal notes, I can only hope #Hercules crosses the ocean to Broadway. This score is glorious and the lullaby in this pack is beautiful!!https://go.bsky.app/3R4hmLZ
November 8, 2025 at 1:47 AM