Mick Craig
@mickcraig.bsky.social
Glaswegian Neuroscientist running a systems neuro lab @uofglasgow.bsky.social. Interests: ephys, interneurons, thalamus, oscillations, dementia, schiz & neuroinflammation. Dad, leftie, runner, wannabe chef, atheist. He/him https://craiglab.org/
Pinned
Hippocampal pyramidal cells of the CA1 region are not a major target of the thalamic nucleus reuniens
Excitatory input from the prefrontal cortex to hippocampus pyramidal cells is commonly believed to be mediated through the thalamic nucleus reuniens brain region. This study shows in rodents that this...
journals.plos.org
Delighted that our main #TeamReuniens paper is finally out in @plosbiology.org. Been a long time in the making, congratulations to Lilya and all the team. A thread to follow soon, after I've had some sleep... #NeuroSkyence
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Mick Craig
@bjennings90.bsky.social absolutely nails it. (www.theguardian.com/commentisfre...)
November 11, 2025 at 6:58 AM
@bjennings90.bsky.social absolutely nails it. (www.theguardian.com/commentisfre...)
Reposted by Mick Craig
A lifehack for turning "non-significant" results into pure gold?
(ICYMI)
statsepi.substack.com/p/one-simple...
(ICYMI)
statsepi.substack.com/p/one-simple...
One simple trick that statisticians hate
If you don't like the results, just ignore the control group
statsepi.substack.com
October 30, 2025 at 10:29 AM
A lifehack for turning "non-significant" results into pure gold?
(ICYMI)
statsepi.substack.com/p/one-simple...
(ICYMI)
statsepi.substack.com/p/one-simple...
November means it's time to start auditioning cheeses to see which ones can earn their spot on our Christmas dinner table... 🤤
November 2, 2025 at 4:40 PM
November means it's time to start auditioning cheeses to see which ones can earn their spot on our Christmas dinner table... 🤤
Reposted by Mick Craig
Today for #FluorescenceFriday I’m sharing a 👻Halloween-themed🎃 neural crest explant “web of cells” from Julia Godinez, a 4th year @ucdavis.bsky.social graduate student in the lab. She is studying mechanisms driving conserved and divergent cranial neural crest migration and differentiation. #DevBio
October 17, 2025 at 8:21 PM
Today for #FluorescenceFriday I’m sharing a 👻Halloween-themed🎃 neural crest explant “web of cells” from Julia Godinez, a 4th year @ucdavis.bsky.social graduate student in the lab. She is studying mechanisms driving conserved and divergent cranial neural crest migration and differentiation. #DevBio
Reposted by Mick Craig
*The uninvited guest* (sound on this time!)
Third week of observing scary things under the microscope: watching #SARSCoV2🟣 positive cells arrive in the brain. Note it's still inside a blood vessel and being checked by astrocytes🟢and microglia🔵. What happens next? 😨 #FluorescenceFriday
Third week of observing scary things under the microscope: watching #SARSCoV2🟣 positive cells arrive in the brain. Note it's still inside a blood vessel and being checked by astrocytes🟢and microglia🔵. What happens next? 😨 #FluorescenceFriday
October 17, 2025 at 6:53 PM
*The uninvited guest* (sound on this time!)
Third week of observing scary things under the microscope: watching #SARSCoV2🟣 positive cells arrive in the brain. Note it's still inside a blood vessel and being checked by astrocytes🟢and microglia🔵. What happens next? 😨 #FluorescenceFriday
Third week of observing scary things under the microscope: watching #SARSCoV2🟣 positive cells arrive in the brain. Note it's still inside a blood vessel and being checked by astrocytes🟢and microglia🔵. What happens next? 😨 #FluorescenceFriday
Reposted by Mick Craig
For #FluorescenceFriday - projection neurons from the mouse prefrontal cortex to the locus coeruleus 🔴 with Fos labeling activated cells 🟢. Image credit to the Circuits team in the Translational Neuroscience Division @lieberinstitute.bsky.social 🧠🔬🧪
October 24, 2025 at 11:45 AM
For #FluorescenceFriday - projection neurons from the mouse prefrontal cortex to the locus coeruleus 🔴 with Fos labeling activated cells 🟢. Image credit to the Circuits team in the Translational Neuroscience Division @lieberinstitute.bsky.social 🧠🔬🧪
Another #FluorescenceFriday image here, from an ongoing project studying circuitry of the retrosplenial cortex. Here we are using rabies to map the inputs specifically to the deep pyramidal cells (L5). Cyan shows the deep cells and magenta shows their presynaptic partners. #NeuroSkyence
October 24, 2025 at 9:44 AM
Another #FluorescenceFriday image here, from an ongoing project studying circuitry of the retrosplenial cortex. Here we are using rabies to map the inputs specifically to the deep pyramidal cells (L5). Cyan shows the deep cells and magenta shows their presynaptic partners. #NeuroSkyence
Reposted by Mick Craig
𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻??
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
The astrocytic ensemble acts as a multiday trace to stabilize memory - Nature
Emotional experience evokes signalling in astrocytes, which form an ensemble that is reinforced by secondary astrocytic state changes resulting from repeated experience, leading to memory stabilizatio...
www.nature.com
October 21, 2025 at 5:57 PM
𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻??
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
Reposted by Mick Craig
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
October 15, 2025 at 6:33 AM
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
Reposted by Mick Craig
Excitatory input from #PrefrontalCortex to #hippocampus pyramidal cells is believed to be mediated through the thalamic nucleus reuniens. @mickcraig.bsky.social &co show in rodents that this brain pathway is unexpectedly minor, contrary to assumptions in the field @plosbiology.org 🧪 plos.io/48u6mle
October 14, 2025 at 1:10 PM
Excitatory input from #PrefrontalCortex to #hippocampus pyramidal cells is believed to be mediated through the thalamic nucleus reuniens. @mickcraig.bsky.social &co show in rodents that this brain pathway is unexpectedly minor, contrary to assumptions in the field @plosbiology.org 🧪 plos.io/48u6mle
Reposted by Mick Craig
I'll say it: I think its rly annoying and frankly amateurish that writers are constantly told their villains must be understandable or have sympathetic motivation to be interesting or realistic when all our big villains irl are in fact rich, stupid, selfish, trickster dillweeds and always have been
October 13, 2025 at 4:55 PM
I'll say it: I think its rly annoying and frankly amateurish that writers are constantly told their villains must be understandable or have sympathetic motivation to be interesting or realistic when all our big villains irl are in fact rich, stupid, selfish, trickster dillweeds and always have been
Delighted that our main #TeamReuniens paper is finally out in @plosbiology.org. Been a long time in the making, congratulations to Lilya and all the team. A thread to follow soon, after I've had some sleep... #NeuroSkyence
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Hippocampal pyramidal cells of the CA1 region are not a major target of the thalamic nucleus reuniens
Excitatory input from the prefrontal cortex to hippocampus pyramidal cells is commonly believed to be mediated through the thalamic nucleus reuniens brain region. This study shows in rodents that this...
journals.plos.org
October 13, 2025 at 8:45 PM
Delighted that our main #TeamReuniens paper is finally out in @plosbiology.org. Been a long time in the making, congratulations to Lilya and all the team. A thread to follow soon, after I've had some sleep... #NeuroSkyence
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Did a slightly early Thanksgiving meal today and my pumpkin pie set! I take a somewhat freestyle approach in the kitchen so have a patchy track record with pumpkin pie, but I actually read a recipe and measured a little today. Enjoy tomorrow for those to celebrate! 🍁🇨🇦
October 12, 2025 at 6:50 PM
Did a slightly early Thanksgiving meal today and my pumpkin pie set! I take a somewhat freestyle approach in the kitchen so have a patchy track record with pumpkin pie, but I actually read a recipe and measured a little today. Enjoy tomorrow for those to celebrate! 🍁🇨🇦
Reposted by Mick Craig
No comment on what THIS company is doing because (*shudder*), but if you want to follow REAL scientists on this look at groups like: www.ucdavis.edu/news/brain-c...
publicly 👏 funded 👏 research 👏 changing 👏 lives 👏
publicly 👏 funded 👏 research 👏 changing 👏 lives 👏
Brain-Computer Interface Allows Man With ALS to ‘Speak’
A brain-computer interface (BCI) developed by UC Davis Health accurately translates brain signals into speech. The device implanted in the brain of a man with ALS is the most accurate system of its ki...
www.ucdavis.edu
October 12, 2025 at 9:17 AM
No comment on what THIS company is doing because (*shudder*), but if you want to follow REAL scientists on this look at groups like: www.ucdavis.edu/news/brain-c...
publicly 👏 funded 👏 research 👏 changing 👏 lives 👏
publicly 👏 funded 👏 research 👏 changing 👏 lives 👏
I finally made a lab website, a mere 9 years after starting... oops. It's still a bit rudimentary but it'll do for now... craiglab.org
Craig Lab
Translational neurobiology
craiglab.org
October 11, 2025 at 11:28 PM
I finally made a lab website, a mere 9 years after starting... oops. It's still a bit rudimentary but it'll do for now... craiglab.org
Reposted by Mick Craig
Not going to lie, this is spot on and frankly, yeah, this IS how I feel and if I wasn't clear, placing this because she did it better than I would have and to be certain, in less time. 😜
If this is #cringe, then cringe away because I'm not.
If this is #cringe, then cringe away because I'm not.
From the CringeTikToks community on Reddit: Brutally spot-on. 😳👇
Explore this post and more from the CringeTikToks community
www.reddit.com
October 11, 2025 at 12:40 PM
Not going to lie, this is spot on and frankly, yeah, this IS how I feel and if I wasn't clear, placing this because she did it better than I would have and to be certain, in less time. 😜
If this is #cringe, then cringe away because I'm not.
If this is #cringe, then cringe away because I'm not.
Are we still doing #FluorescenceFriday? #NeuroSkyence
October 10, 2025 at 3:33 PM
Are we still doing #FluorescenceFriday? #NeuroSkyence
Reposted by Mick Craig
For Starmer and Labour the point is to beat Reform in elections. Maybe this will work, to that end.
But for the public and the nation, the important thing is to defeat the fascism and its racism. And this approach will achieve the very opposite
But for the public and the nation, the important thing is to defeat the fascism and its racism. And this approach will achieve the very opposite
Once again Labour's strategy is to say that racism is terrible, and therefore we will defeat the racists by giving them almost everything they want
bylinetimes.com/2025/10/01/k...
bylinetimes.com/2025/10/01/k...
Keir Starmer's Farage-Dominated Conference Takes Labour Up a 'Darker Path' Towards a Reform Government
The Prime Minister's condemnations of Reform's racist rhetoric, was undermined by him accepting the central premise of Nigel Farage's anti-migrant politics, argues Adam Bienkov
bylinetimes.com
October 2, 2025 at 6:49 AM
For Starmer and Labour the point is to beat Reform in elections. Maybe this will work, to that end.
But for the public and the nation, the important thing is to defeat the fascism and its racism. And this approach will achieve the very opposite
But for the public and the nation, the important thing is to defeat the fascism and its racism. And this approach will achieve the very opposite
Fully funded #FindAPhD! We'll be studying neurobiology of motivation in mice hunting crickets, using a combination of genetic manipulations, behaviour and in vivo ephys. Co-suprvised by the amazing @agonru.bsky.social and Gareth Arnott at QUB. #Neuroskyence Pls share
www.gla.ac.uk/postgraduate...
www.gla.ac.uk/postgraduate...
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Animal Biology in Health & Disease - Mick Craig
www.gla.ac.uk
September 30, 2025 at 9:40 PM
Fully funded #FindAPhD! We'll be studying neurobiology of motivation in mice hunting crickets, using a combination of genetic manipulations, behaviour and in vivo ephys. Co-suprvised by the amazing @agonru.bsky.social and Gareth Arnott at QUB. #Neuroskyence Pls share
www.gla.ac.uk/postgraduate...
www.gla.ac.uk/postgraduate...
Reposted by Mick Craig
A rather 'unique' paper from our lab is online in @cp-cellreports.bsky.social now. Unique in the sense that I don't think anyone else will be rushing to optotag cortical interneurons in the early postnatal brain... because it is nigh on impossible!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
GABAergic circuits reflect different requirements for sensory integration in postnatal mouse neocortex
Information transfer in mammalian cerebral cortex is dependent on GABAergic interneuron circuits that are widely assumed to be uniform across the neoc…
www.sciencedirect.com
September 18, 2025 at 4:16 PM
A rather 'unique' paper from our lab is online in @cp-cellreports.bsky.social now. Unique in the sense that I don't think anyone else will be rushing to optotag cortical interneurons in the early postnatal brain... because it is nigh on impossible!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Mick Craig
July 8, 2025 at 4:17 PM
Reposted by Mick Craig
Do you ever sign a peer review? I reviewed a paper last night and the journal have the option to sign the review. I almost did but then decided against it. #NeuroSkyence
September 27, 2025 at 8:06 AM
Do you ever sign a peer review? I reviewed a paper last night and the journal have the option to sign the review. I almost did but then decided against it. #NeuroSkyence
Reposted by Mick Craig
I guess mathematically speaking you can’t count zeros
Digital ID cards to have “countless benefits” for Brits says PM
www.channel4.com/news/digital...
www.channel4.com/news/digital...
Digital ID cards to have “countless benefits” for Brits says PM
You won't have to carry it - but new digital ID cards will be compulsory for anyone who wants to work in the UK, under new plans outlined by Sir Keir Starmer.
www.channel4.com
September 26, 2025 at 7:24 PM
I guess mathematically speaking you can’t count zeros
I don't understand #UCU at the moment. Am I happy having had several years of continuous pay cuts with very below-inflation pay rises? Absolutely not. But UK higher education is in crisis. Do I want to go on strike to force pay rises that may result in my colleagues losing their jobs? Also: no.🤦♂️
September 26, 2025 at 7:44 PM
I don't understand #UCU at the moment. Am I happy having had several years of continuous pay cuts with very below-inflation pay rises? Absolutely not. But UK higher education is in crisis. Do I want to go on strike to force pay rises that may result in my colleagues losing their jobs? Also: no.🤦♂️