Marc Perry
@mdperry.bsky.social
Biochemist (by training), Geneticist (by osmosis), Bioinformatician (by experience). Possesses an extremely peculiar sense of humor/humour.
Reposted by Marc Perry
Wow! This looks fascinating
"Our findings uncovered a species survival strategy in which telomerase RNA extends telomeres for the next generation by hitchhiking on introns of germline-expressed genes." 🤯
#Celegans 🧪
#Celegans 🧪
Nematode telomerase RNA hitchhikes on introns of germline–up-regulated genes
Telomerase is a ribonucleoprotein complex that elongates telomeric DNA, ensuring germline immortality. In this study, we identified the Caenorhabditis elegans telomerase RNA component 1 (terc-1), as t...
www.science.org
October 24, 2025 at 6:34 AM
Wow! This looks fascinating
Reposted by Marc Perry
A potent and plain-spoken defence of DEI in science - from the experts. Representation *matters*.
October 23, 2025 at 10:03 PM
A potent and plain-spoken defence of DEI in science - from the experts. Representation *matters*.
Reposted by Marc Perry
John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale, which has paved the way for quantum computing. ⚛️🧪
Groundbreaking quantum-tunnelling experiments win physics Nobel
John Clarke, Michel Devoret and John Martinis discovered quantum physics on a macroscopic scale, paving the way for quantum computing.
go.nature.com
October 7, 2025 at 2:08 PM
John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale, which has paved the way for quantum computing. ⚛️🧪
Reposted by Marc Perry
Are you an early career scientist who wants to get specialist training in C. elegans model for your laboratory research? we co-organize again the EMBO C. elegans course! Do not miss applying!
🪱 Ready to take your C. elegans skills to the next level? Join our #EMBOCelegans course!
🎯 Learn hands-on genome editing, AI-driven imaging, microfluidics & uncover development, physiology & evolutionary insights.
📍 EMBL Heidelberg
📅 23 – 29 Mar 2026
👉 Apply by 8 Dec: s.embl.org/cel26-01-bl
🎯 Learn hands-on genome editing, AI-driven imaging, microfluidics & uncover development, physiology & evolutionary insights.
📍 EMBL Heidelberg
📅 23 – 29 Mar 2026
👉 Apply by 8 Dec: s.embl.org/cel26-01-bl
October 5, 2025 at 1:38 PM
Are you an early career scientist who wants to get specialist training in C. elegans model for your laboratory research? we co-organize again the EMBO C. elegans course! Do not miss applying!
Reposted by Marc Perry
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
August 27, 2025 at 8:56 PM
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Reposted by Marc Perry
Fun fact: diluted tattoo inks and washes make pretty decent carbon sources for NTMs.
Eight of 63 clients of a tattoo artist using a homemade (witch hazel-based) diluent developed an NTM skin and soft tissue infection.
Just say no to 🙅♂️homemade tattoo ink
#IDSky
academic.oup.com/cid/advance-...
Just say no to 🙅♂️homemade tattoo ink
#IDSky
academic.oup.com/cid/advance-...
Nontuberculous Mycobacterium Skin Infections Associated With One Tattoo Studio—Oregon, January–April 2023
Abstract. Surgical, cosmetic, and tattooing procedures can lead to nontuberculous mycobacterium skin and soft tissue infections. Eight Oregonians developed
academic.oup.com
August 22, 2025 at 9:11 PM
Fun fact: diluted tattoo inks and washes make pretty decent carbon sources for NTMs.
Reposted by Marc Perry
You had me at "supergiant cannibals." 😱 Gotta love the world of ciliates. Good🧵⬇️
August 26, 2025 at 11:38 PM
You had me at "supergiant cannibals." 😱 Gotta love the world of ciliates. Good🧵⬇️
As a member of the Toronto Perl Mongers I volunteered at the TPRC held in Toronto in 2023. This blog post from Bryan Katz relates his experience with Perl in general, and specifically at that conference #relatable #perl
www.perl.com/article/my-g...
www.perl.com/article/my-g...
My Guilty Perl Obsession
Perl came for free. How much have I contributed in return? Absolutely nothing.
www.perl.com
August 26, 2025 at 5:44 PM
As a member of the Toronto Perl Mongers I volunteered at the TPRC held in Toronto in 2023. This blog post from Bryan Katz relates his experience with Perl in general, and specifically at that conference #relatable #perl
www.perl.com/article/my-g...
www.perl.com/article/my-g...
Reposted by Marc Perry
Exciting new study showing extensive Argonaute protein family gain, loss, neofunctionalization + more among species, by PhD student Daniel Fusca with @katjakasimatis.bsky.social + Hongyu Zhu; Now out @genomebiolevol.bsky.social #celegans #rna doi.org/10.1093/gbe/...
Dynamic Birth and Death of Argonaute Gene Family Functional Repertoire Across Caenorhabditis Nematodes
Abstract. Diverse small RNA pathways, composed of Argonaute effector proteins and their bound small RNA molecules, define critical systems for regulating g
doi.org
June 12, 2025 at 2:03 AM
Exciting new study showing extensive Argonaute protein family gain, loss, neofunctionalization + more among species, by PhD student Daniel Fusca with @katjakasimatis.bsky.social + Hongyu Zhu; Now out @genomebiolevol.bsky.social #celegans #rna doi.org/10.1093/gbe/...
Reposted by Marc Perry
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.05.13.653874v1
May 18, 2025 at 12:03 AM
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.05.13.653874v1
Reposted by Marc Perry
Whoah!!
I am pleased to share our latest manuscript, a collaboration with my @sickkidsto.bsky.socical colleague Dr. Ran Kafri. Led by PhD student Rachel Webster, who found that the CDK4/Rb/E2F pathway regulates metabolism to prevent premature aging in C. elegans. www.nature.com/articles/s41...
CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans - Heredity
Heredity - CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans
www.nature.com
May 18, 2025 at 3:07 PM
Whoah!!
Reposted by Marc Perry
The Provisional Mortality statistics have been updated by the Australian Bureau of Statistics (ABS), up to January 2025.
Here are the deaths where the underlying cause of death was certified by a doctor as COVID-19 (22,357 deaths).
#COVID19 #Australia
🧵
Here are the deaths where the underlying cause of death was certified by a doctor as COVID-19 (22,357 deaths).
#COVID19 #Australia
🧵
May 18, 2025 at 10:27 AM
The Provisional Mortality statistics have been updated by the Australian Bureau of Statistics (ABS), up to January 2025.
Here are the deaths where the underlying cause of death was certified by a doctor as COVID-19 (22,357 deaths).
#COVID19 #Australia
🧵
Here are the deaths where the underlying cause of death was certified by a doctor as COVID-19 (22,357 deaths).
#COVID19 #Australia
🧵
Reposted by Marc Perry
The US has cut the equivalent of 3X the total annual CIHR budget so far this year, revealing both how low the CIHR budget is and how utterly draconian the White House has treated one of the most precious and successful institutions the US has ever built.
Update of my analysis of funding missing in FY2025 compared to FY2024.
Bottom line: The missing amount is estimated to be $2.05 B from non-competitive renewals and $0.83 B from new and competitive renewals.
Total: $2.88 B
Bottom line: The missing amount is estimated to be $2.05 B from non-competitive renewals and $0.83 B from new and competitive renewals.
Total: $2.88 B
May 13, 2025 at 10:29 PM
The US has cut the equivalent of 3X the total annual CIHR budget so far this year, revealing both how low the CIHR budget is and how utterly draconian the White House has treated one of the most precious and successful institutions the US has ever built.
Reposted by Marc Perry
Huge thanks to Federico Gueli for his tips on new lineages to watch out for, eg
bsky.app/profile/siam...
🧵
bsky.app/profile/siam...
🧵
One SC2 variant that i see usually overlooked is XFC that is basically LP.8.1.1 with the NTD from LF.7 ,
interestingly it has been sampled two times in travelers coming into US from Ethiopia in a period spanning four months suggesting it may have high prevalence there along with XFJ .
interestingly it has been sampled two times in travelers coming into US from Ethiopia in a period spanning four months suggesting it may have high prevalence there along with XFJ .
May 10, 2025 at 9:20 AM
Huge thanks to Federico Gueli for his tips on new lineages to watch out for, eg
bsky.app/profile/siam...
🧵
bsky.app/profile/siam...
🧵
@augustorendon.bsky.social It was such a good idea now everyone is copying you. Who knew?
🇨🇦 Canada is sequencing 100,000 genomes to revolutionize healthcare. From rare diseases to drug safety in kids, this $200M effort will drive AI-powered precision health—and ensure breakthroughs reflect Canada’s diverse population. It's our turn. #Genomics genomecanada.ca/how-100000-g...
How 100,000 Genomes Can Help Re-define Health Care in Canada - GenomeCanada
What if your doctor could really see you? Not just the physical you, but the genetic you? Genetic variation causes cancer, rare disease and hereditary illness. It can be linked to drastically differe...
genomecanada.ca
May 10, 2025 at 7:53 PM
@augustorendon.bsky.social It was such a good idea now everyone is copying you. Who knew?
Reposted by Marc Perry
🪱 Worm people! C. elegans Mentor Match sign-ups close May 8:
👩🔬 Be matched with a mentor → custom career guidance
🤝 Join a peer group → swap tips & stay accountable
✨ Both → double support
Tell your lab mates and help us grow the program!
👩🔬 Be matched with a mentor → custom career guidance
🤝 Join a peer group → swap tips & stay accountable
✨ Both → double support
Tell your lab mates and help us grow the program!
Mentee sign-up for the 2025 C. elegans Community Mentor Match program
The 2025 C. elegans Community Mentor Match is open to graduate students, postdocs, and faculty at any career stage. This survey collects information to help the committee (a) identify the most appropr...
docs.google.com
April 29, 2025 at 7:15 PM
🪱 Worm people! C. elegans Mentor Match sign-ups close May 8:
👩🔬 Be matched with a mentor → custom career guidance
🤝 Join a peer group → swap tips & stay accountable
✨ Both → double support
Tell your lab mates and help us grow the program!
👩🔬 Be matched with a mentor → custom career guidance
🤝 Join a peer group → swap tips & stay accountable
✨ Both → double support
Tell your lab mates and help us grow the program!
Reposted by Marc Perry
Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans.
Email or DM me to find out more. Please share & repost!
Email or DM me to find out more. Please share & repost!
Postdoctoral Research Associate, Biology
About the Opportunity Job Summary The Apfeld Lab at Northeastern University is seeking a postdoctoral researcher to investigate how genes work together to determine the maximum lifespan of the nematod...
northeastern.wd1.myworkdayjobs.com
April 29, 2025 at 8:54 PM
Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans.
Email or DM me to find out more. Please share & repost!
Email or DM me to find out more. Please share & repost!
That seems like such a shallow depiction of all of C. elegans’ behaviours and strengths. Clearly he never spent an hour watching some crawl around a plate. Oh well, who has time to educate all of the plebes.
Michael Eisen (who is at mbeisen dot bsky dot com) answered a tweet asking for people’s least favorite model organism with:
“C. elegans. They wriggle forwards, they wriggle backwards, and sometimes they fuck”
“C. elegans. They wriggle forwards, they wriggle backwards, and sometimes they fuck”
April 23, 2025 at 1:17 PM
That seems like such a shallow depiction of all of C. elegans’ behaviours and strengths. Clearly he never spent an hour watching some crawl around a plate. Oh well, who has time to educate all of the plebes.
Reposted by Marc Perry
Are you using Bluesky primarily as a source for links but are overwhelmed by the massive inflow of posts and doom?
I wrote a small #Emacs package to fetch links from your #Bsky feed, sort them by frequency and time posted, and present them in an #orgmode buffer.
github.com/rtrppl/hotsky
I wrote a small #Emacs package to fetch links from your #Bsky feed, sort them by frequency and time posted, and present them in an #orgmode buffer.
github.com/rtrppl/hotsky
April 23, 2025 at 5:37 AM
Are you using Bluesky primarily as a source for links but are overwhelmed by the massive inflow of posts and doom?
I wrote a small #Emacs package to fetch links from your #Bsky feed, sort them by frequency and time posted, and present them in an #orgmode buffer.
github.com/rtrppl/hotsky
I wrote a small #Emacs package to fetch links from your #Bsky feed, sort them by frequency and time posted, and present them in an #orgmode buffer.
github.com/rtrppl/hotsky
Reposted by Marc Perry
That’s a wrap on our first-ever Full Length 16S rRNA @pacbio.bsky.social Sequencing & Bioinformatics course! 🧪💻
From lab bench to species-level insight, participants processed their own data through QC, DADA2, taxonomic annotation & more, to create figures like this! 🧬👇
From lab bench to species-level insight, participants processed their own data through QC, DADA2, taxonomic annotation & more, to create figures like this! 🧬👇
April 23, 2025 at 10:12 AM
That’s a wrap on our first-ever Full Length 16S rRNA @pacbio.bsky.social Sequencing & Bioinformatics course! 🧪💻
From lab bench to species-level insight, participants processed their own data through QC, DADA2, taxonomic annotation & more, to create figures like this! 🧬👇
From lab bench to species-level insight, participants processed their own data through QC, DADA2, taxonomic annotation & more, to create figures like this! 🧬👇