https://marand-lab.github.io/
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
doi.org/10.1016/j.ce...
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
doi.org/10.1016/j.ce...
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
@dartmouthbcb.bsky.social @futurepislack.bsky.social
@dartmouthbcb.bsky.social @futurepislack.bsky.social
Our multiple discovery filtering (MDF) approach can be used in any model organism and makes it really easy to find trans-regulatory variants.
Software coming soon! 🧪
www.biorxiv.org/content/10.1...
Our multiple discovery filtering (MDF) approach can be used in any model organism and makes it really easy to find trans-regulatory variants.
Software coming soon! 🧪
www.biorxiv.org/content/10.1...
unc.peopleadmin.com/postings/307...
unc.peopleadmin.com/postings/307...
"Single Cell Multi-Omics Reveals Rare Biosynthetic Cell Types in the Medicinal Tree Camptotheca acuminata"
Product of an NSF-EAGER award that I was co-PI from 2023-2025 (www.nsf.gov/awardsearch/...).
"Single Cell Multi-Omics Reveals Rare Biosynthetic Cell Types in the Medicinal Tree Camptotheca acuminata"
Product of an NSF-EAGER award that I was co-PI from 2023-2025 (www.nsf.gov/awardsearch/...).
Collaboration with the Giessen and Pi labs
Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
Collaboration with the Giessen and Pi labs
Congratulations to co-first authors Y Hoang (@hoanghamyy.bsky.social) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP
jasonjwilliamsny.github.io/grfp2025/
The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP
jasonjwilliamsny.github.io/grfp2025/
www.jessicacalarco.com/teaching-res...
www.jessicacalarco.com/teaching-res...
Chromatin accessibility in rice & related grasses: how regulatory DNA elements evolve across cell types & species; identifying potential silencers.
Chromatin accessibility in rice & related grasses: how regulatory DNA elements evolve across cell types & species; identifying potential silencers.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
With David, nothing is impossible !
With David, nothing is impossible !
CREsted allows you to train sequence-to-function models tailored to cell type-specific enhancers (including synthetic enhancer design) www.biorxiv.org/content/10.1... github.com/aertslab/cre...
(Zoom registration link and more information in thread!)
🧵
CREsted allows you to train sequence-to-function models tailored to cell type-specific enhancers (including synthetic enhancer design) www.biorxiv.org/content/10.1... github.com/aertslab/cre...
eCIS for plant protein delivery: tinyurl.com/mrx4d878
R2 for targeted insertion: tinyurl.com/5n73za6h
Transient expression: tinyurl.com/38p2ud6w
Chemotaxis assay: tinyurl.com/3nw9haes
More ⬇️
eCIS for plant protein delivery: tinyurl.com/mrx4d878
R2 for targeted insertion: tinyurl.com/5n73za6h
Transient expression: tinyurl.com/38p2ud6w
Chemotaxis assay: tinyurl.com/3nw9haes
More ⬇️
Drought recovery in plants triggers a cell-state-specific immune activation.
doi.org/10.1038/s414...
Read thread below 👇
Drought recovery in plants triggers a cell-state-specific immune activation.
doi.org/10.1038/s414...
Read thread below 👇