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madelineandrews.bsky.social
Madeline Andrews
@madelineandrews.bsky.social
340 followers 230 following 8 posts
Developmental neuroscience with a bioengineering flair | Using stem cell models to study brain development & disease | Assistant Professor at Arizona State University |
Postdoc @UCSF I PhD @UCLA | 🧠🧫🌵☀️
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madelineandrews.bsky.social
That's a wrap on #sfn 2025! First big conference as a lab - was wonderful to see old friends, share our work, and hear great science
November 19, 2025 at 7:19 PM
Reposted by Madeline Andrews
cterminiphd.bsky.social
🚨 Calling all postdocs 🚨

We are soliciting applications to our 8th cohort of Fred Hutch Dr. Eddie Méndez Scholars! Awardees will be invited to present at a symposium celebrating their achievements 🧵

Apply here 👇 👇 👇
apply.interfolio.com/176955
📆 Applications due 2/1/2026
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
November 12, 2025 at 5:28 PM
Reposted by Madeline Andrews
zoltan-molnar.bsky.social
First-ever atlas of brain development shows how stem cells turn into neurons
There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!
November 11, 2025 at 12:13 AM
Reposted by Madeline Andrews
leadingedgeprogram.bsky.social
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.

The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.

www.leadingedgesymposium.org/apply/
Candid photo of Zara Weinberg. She has short red hair, bangs and glasses. She is laughing.
November 5, 2025 at 5:48 PM
Reposted by Madeline Andrews
kuba-sedzinski.bsky.social
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
September 22, 2025 at 9:37 AM
Reposted by Madeline Andrews
labwaggoner.bsky.social
Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling @cellcellpress.bsky.social @travisfaust.bsky.social
www.cell.com/cell/fulltex...
September 11, 2025 at 3:32 PM
Reposted by Madeline Andrews
ygilad.bsky.social
My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. I hope people will find it useful.

It’s available on Amazon: tinyurl.com/mx2hewen
January 17, 2025 at 2:30 PM
Reposted by Madeline Andrews
cedricboeckx.bsky.social
New preprint by @labnowakowski.bsky.social
& colleagues: Sex differences in the developing human cortex intersect with genetic risk of neurodevelopmental disorders, identifying “two points of vulnerability contributing to the sex-biased penetrance in neurodevelopmental disorders” 🧪🧠🧬
Sex differences in the developing human cortex intersect with genetic risk of neurodevelopmental disorders
Autism is highly heritable and diagnosed more frequently in males than females. To identify neurodevelopmental processes that might present sex-biased vulnerability, we generated transcriptomic and ep...
www.biorxiv.org
September 5, 2025 at 9:42 AM
Reposted by Madeline Andrews
vanderhaeghenp2.bsky.social
New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social
Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics
Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...
www.biorxiv.org
September 3, 2025 at 12:19 PM
Reposted by Madeline Andrews
liddelowsa.bsky.social
Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_...
#Neuroscience #Postdoc #ResearchOpportunity
June 15, 2025 at 4:20 PM
Reposted by Madeline Andrews
labfame.bsky.social
How does the brain 🧠 change around the clock 🕰️? Can this inform treatments?

Learn more in a new review from the lab 'Harnessing the #circadian nature of the choroid plexus and cerebrospinal fluid' ➡️ npj Biological Timing & Sleep | #Nature @natureportfolio.nature.com
www.nature.com/articles/s44...
A The major components of the CSF system include CSF, choroid plexus, and circumventricular organs. These systems change their properties across time of day, including those listed below each component. B Multiple inputs affect the CSF system across time of day.
May 26, 2025 at 9:25 PM
Reposted by Madeline Andrews
debbysilver.bsky.social
Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...
A human-specific enhancer fine-tunes radial glia potency and corticogenesis - Nature
HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence betw...
www.nature.com
May 14, 2025 at 4:09 PM
Reposted by Madeline Andrews
handle.invalid
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!

These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.

Save and share the post!
May 13, 2025 at 7:55 PM
Reposted by Madeline Andrews
brainevodevo.bsky.social
Introducing CellBouncer, a unified demultiplexing toolkit built by nkschaefer.bsky.social to check IDs and keep the riff raff out of single cell genomics datasets, including by using genetic variation as an external ground-truth for ambient RNA removal:

www.biorxiv.org/content/10.1...
March 24, 2025 at 9:48 PM
Reposted by Madeline Andrews
tvierbuchen.bsky.social
Our collaborative project with Matthias Stadtfeld and Jason Mezey labs has now been published. We examined how genetic variation impacts regulation of DNA methylation at the control regions of imprinted genes in naive pluripotent stem cells.

www.cell.com/stem-cell-re...
Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells
Pluripotent stem cells are susceptible to acquiring detrimental epigenetic abnormalities, posing a hurdle to their safe use in biomedical applications. Using pluripotent cells with defined genetic backgrounds, Stadtfeld and colleagues show that genetic variation is a major driver of epigenome stability and identify candidate regulators. These findings will enable novel approaches to stabilize the epigenome of pluripotent cells in culture.
www.cell.com
March 13, 2025 at 8:01 PM
madelineandrews.bsky.social
Exciting new study from @bhadurilab.bsky.social on metabolic regulation of human cortical development!
bhadurilab.bsky.social bhadurilab.bsky.social @bhadurilab.bsky.social · Mar 13
Delighted to share our most recent preprint led by the incredible @MilJessenya and @Jalbsoto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. www.biorxiv.org/content/10.1...
Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions
Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...
www.biorxiv.org
March 14, 2025 at 4:36 AM
Reposted by Madeline Andrews
capearson.bsky.social
Happy International Women's Day!
Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM
@suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩‍🔬🦄
March 8, 2025 at 1:52 PM
Reposted by Madeline Andrews
biologists.bsky.social
The deadline for the following grants is 7 March:
- Scientific Meeting Grants
- Grants from our Fund for Innovations in Sustainable Conferencing
- JCS-FocalPlane Training Grants @jcellsci.bsky.social @focalplane.bsky.social

Find out more and apply at: www.biologists.com/grants
About our grants
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings,…
www.biologists.com
March 3, 2025 at 10:15 AM
Reposted by Madeline Andrews
elizabethcrouch.bsky.social
Grateful for this funding and the opportunity to work with a phenomenal group of scientists to study a novel hypothesis with patient impact. 🧫🔬🥼👶🏻👧🏾👦🏽 @bhadurilab.bsky.social @zeigerlab.bsky.social
stemcell.ucsf.edu/news/scienti...
Scientists Secure $10.3 Million CIRM Grant to Advance Stem-Cell Therapies for Neuropsychiatric Disorders
A team of researchers from the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF and UCLA, along with the UC Santa Cruz Genomics Institute, has been awarded a $10.3 m...
stemcell.ucsf.edu
February 20, 2025 at 2:00 AM
Reposted by Madeline Andrews
pracheeac.bsky.social
🚨Job Alert @arcadiascience.com!

Are you an independent, generative, rigorous scientist that can pivot quickly? Can you apply your unique skills to a wide range of bio & tech problems? Can you work with other stellar scientists skilled in orthogonal domains? Join us!

jobs.lever.co/arcadiascien...
Arcadia Science - Project Scientist
A Bit About Us: We are Arcadia Science. Arcadia is a science company founded and led by scientists. Our mission is to transform evolutionary innovations into real-world solutions by openly developing ...
jobs.lever.co
February 7, 2025 at 3:04 AM
Reposted by Madeline Andrews
nebanovich.bsky.social
Excited to post my first #skySplain about our recent work published yesterday in Nature Genetics! www.nature.com/articles/s41.... One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!
Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis - Nature Genetics
Xenium spatial transcriptomic profiling of pulmonary fibrosis characterizes cell composition dynamics and histopathological features associated with the disease.
www.nature.com
February 4, 2025 at 2:11 PM
Reposted by Madeline Andrews
debbysilver.bsky.social
Happy to share some good news today, and our latest study on DDX3X! Led by super talented @federicamosti.bsky.social we use live imaging, transcriptomics and interaction studies to define how clinically diverse missense mutations in DDX3X influence neural development. dx.plos.org/10.1371/jour...
Multi-modal investigation reveals pathogenic features of diverse DDX3X missense mutations
Author summary DDX3X mutations are associated with neurodevelopmental disorders, including DDX3X syndrome and autism spectrum disorder. DDX3X is an RNA binding protein whose loss of function impairs b...
dx.plos.org
January 23, 2025 at 2:05 AM
Reposted by Madeline Andrews
drsueishaq.bsky.social
The L’Oréal USA For Women in Science program awards women postdoctoral scientists. Candidates must have their PhD, started their postdoctoral research position, and be a U.S. citizen or permanent resident. Applications due 5:00pm ET on Friday, February 14.

www.loreal.com/en/usa/pages...
L'Oréal USA For Women in Science
The L’Oréal USA For Women in Science program has awarded 80 postdoctoral women scientists over $4 million in grants since 2003.
www.loreal.com
January 29, 2025 at 2:03 PM
madelineandrews.bsky.social
We enjoyed discussing two interesting new preprints that evaluate instructive roles of metabolism in neurodevelopment. Thanks for the invitation @dev-journal.bsky.social!
dev-journal.bsky.social Development @dev-journal.bsky.social · Jan 20
In preprints: giving the developing brain the energy it needs

Taylor Pennington and @madelineandrews.bsky.social discuss a recent #preprint "Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations":
https://doi.org/10.1242/dev.204594
In preprints: a new preprint curation initiative from Development
January 27, 2025 at 2:45 AM
Reposted by Madeline Andrews
sloanlab.bsky.social
Hi #neuroscience community! This is one of my favorite posts ever. In close collaboration with @liddelowsa.bsky.social and Ye Zhang, we've built a new tool that we are eager to share! www.webseq.net
WEBseq
share freely
www.webseq.net
January 15, 2025 at 4:21 PM