Pearson Lab
@capearson.bsky.social
Developmental Neurobiology | Autism | Epilepsy | Cortex | Neural stem cells | mouse | human
Assistant Professor Weill Cornell Medicine.
UCLA, University of Sheffield, University of Newcastle upon Tyne alum
capearsonlab.com
(Posts my own opinions)
Assistant Professor Weill Cornell Medicine.
UCLA, University of Sheffield, University of Newcastle upon Tyne alum
capearsonlab.com
(Posts my own opinions)
Congratulations Dr Al-Naama!! So proud of my first PhD mentee and all she’s achieved.
October 1, 2025 at 10:29 PM
Congratulations Dr Al-Naama!! So proud of my first PhD mentee and all she’s achieved.
Reposted by Pearson Lab
Super proud of Njoud and her PhD thesis work.
Here she demonstrates that mitochondrial dysfunction is one of the earliest defects in DRPLA-patient derived neurons. Furthermore, neurodegeneration and ROS accumulation can be rescued with phenylbutyrate treatment.
www.biorxiv.org/content/10.1...
Here she demonstrates that mitochondrial dysfunction is one of the earliest defects in DRPLA-patient derived neurons. Furthermore, neurodegeneration and ROS accumulation can be rescued with phenylbutyrate treatment.
www.biorxiv.org/content/10.1...
Mitochondrial dysfunction precedes neurodegeneration in DRPLA patient-derived neurons, and phenylbutyrate improves survival.
Dentatorubral-pallidoluysian atrophy (DRPLA) is a progressive autosomal-dominant neurodegenerative disorder caused by a CAG repeat expansion in the ATN1 gene, which encodes the transcriptional corepre...
www.biorxiv.org
September 7, 2025 at 5:06 PM
Super proud of Njoud and her PhD thesis work.
Here she demonstrates that mitochondrial dysfunction is one of the earliest defects in DRPLA-patient derived neurons. Furthermore, neurodegeneration and ROS accumulation can be rescued with phenylbutyrate treatment.
www.biorxiv.org/content/10.1...
Here she demonstrates that mitochondrial dysfunction is one of the earliest defects in DRPLA-patient derived neurons. Furthermore, neurodegeneration and ROS accumulation can be rescued with phenylbutyrate treatment.
www.biorxiv.org/content/10.1...
Might have to update my website with this image….🧠🧪
August 7, 2025 at 7:36 PM
Might have to update my website with this image….🧠🧪
Paper submitted! It’s just the beginning but super grateful to all our co-authors🤞🏻🧠⚡️🧪
August 7, 2025 at 12:06 AM
Paper submitted! It’s just the beginning but super grateful to all our co-authors🤞🏻🧠⚡️🧪
Enjoyed my time at the @foxp1foundation.bsky.social meeting in the Netherlands. So great to see lots of exciting #FOXP1 related research and meet so many inspiring parents 🦊🧪
June 21, 2025 at 7:36 PM
Enjoyed my time at the @foxp1foundation.bsky.social meeting in the Netherlands. So great to see lots of exciting #FOXP1 related research and meet so many inspiring parents 🦊🧪
Know any great developmental neurobiologists looking for a post doc position?
Are you looking for an adventure with cerebral organoids in New York City?
We are looking for an enthusiastic new team member!
Feel free to DM or email me 🧪 🧠 🍎
#science #neurodev #neurobiology #neuroscience #devbio
Are you looking for an adventure with cerebral organoids in New York City?
We are looking for an enthusiastic new team member!
Feel free to DM or email me 🧪 🧠 🍎
#science #neurodev #neurobiology #neuroscience #devbio
June 7, 2025 at 11:59 PM
Know any great developmental neurobiologists looking for a post doc position?
Are you looking for an adventure with cerebral organoids in New York City?
We are looking for an enthusiastic new team member!
Feel free to DM or email me 🧪 🧠 🍎
#science #neurodev #neurobiology #neuroscience #devbio
Are you looking for an adventure with cerebral organoids in New York City?
We are looking for an enthusiastic new team member!
Feel free to DM or email me 🧪 🧠 🍎
#science #neurodev #neurobiology #neuroscience #devbio
Happy to contribute to this methods paper from our collaborators at University of Michigan - it was an exciting day when vitrified cerebral organoids arrived! 🧪 🧠 👩🔬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Cryopreservation of Human Cortical Organoids Using Vitrification
Cryopreservation at ultra-low temperatures is a valuable tool for preserving cells and tissues used in research. However, few protocols exist for the preservation of brain organoid models. Current met...
www.biorxiv.org
April 21, 2025 at 4:18 PM
Happy to contribute to this methods paper from our collaborators at University of Michigan - it was an exciting day when vitrified cerebral organoids arrived! 🧪 🧠 👩🔬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
👏🏻👏🏻👏🏻https://www.cnn.com/2025/04/09/health/nobel-laureate-research-funding-patapoutian/index.html
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
www.cnn.com
April 9, 2025 at 3:25 PM
👏🏻👏🏻👏🏻https://www.cnn.com/2025/04/09/health/nobel-laureate-research-funding-patapoutian/index.html
#fluorescencefriday 🧪🧠🧫😍 I ❤️ neural stem cells
March 28, 2025 at 1:31 PM
#fluorescencefriday 🧪🧠🧫😍 I ❤️ neural stem cells
Can finally breathe and celebrate that my R01 application has been funded! 🧪🧠🥳 #GLUT1 #neurobiology
March 26, 2025 at 8:33 PM
Can finally breathe and celebrate that my R01 application has been funded! 🧪🧠🥳 #GLUT1 #neurobiology
Excited to see the latest preprint from the Badhuri lab at UCLA 🧠🧫🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions
Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...
www.biorxiv.org
March 11, 2025 at 2:36 PM
Excited to see the latest preprint from the Badhuri lab at UCLA 🧠🧫🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Happy International Women's Day!
Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM
@suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩🔬🦄
Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM
@suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩🔬🦄
March 8, 2025 at 1:52 PM
Happy International Women's Day!
Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM
@suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩🔬🦄
Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM
@suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩🔬🦄
Fab new study on #FOXP1 and its role during cortical development from Gena Konopka and her team 🧪🧠🦊👏
Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development
Ortiz et al. leverage mice with loss of FOXP1 in their cortical progenitors. Detailed
cell-type-specific genomic and epigenetic alterations are described, with key findings
in progenitors related to a...
www.cell.com
March 8, 2025 at 12:43 PM
Fab new study on #FOXP1 and its role during cortical development from Gena Konopka and her team 🧪🧠🦊👏
Reposted by Pearson Lab
Try this 👇 to access era commons, and view the rest of the thread for access solutions to PubMed, etc.
Add to hosts file:
128.231.210.88 public.era.nih.gov
128.231.210.105 www.era.nih.gov
Or alternatively, just set the nameserver your computer is using to 1.0.0.1 (Cloudflare's nameserver still correctly resolves nih.gov domains).
128.231.210.88 public.era.nih.gov
128.231.210.105 www.era.nih.gov
Or alternatively, just set the nameserver your computer is using to 1.0.0.1 (Cloudflare's nameserver still correctly resolves nih.gov domains).
National Institutes of Health (NIH)
Official website of the National Institutes of Health (NIH). NIH is one of the world's foremost medical research centers. An agency of the U.S. Department of Health and Human Services, the NIH is the ...
nih.gov
March 2, 2025 at 12:39 PM
Try this 👇 to access era commons, and view the rest of the thread for access solutions to PubMed, etc.
Reposted by Pearson Lab
Johns Hopkins officials said the NIH funding cut puts at risk approximately 600 current and ongoing clinical trials at Hopkins, including open clinical trials in cancer, pediatrics and children’s health, heart and vascular studies and the aging brain. www.thebaltimorebanner.com/education/hi...
Johns Hopkins sues federal government over NIH funds
Johns Hopkins University joined several universities in a lawsuit on Monday evening suing the federal government over NIH funding.
www.thebaltimorebanner.com
February 11, 2025 at 5:34 PM
Johns Hopkins officials said the NIH funding cut puts at risk approximately 600 current and ongoing clinical trials at Hopkins, including open clinical trials in cancer, pediatrics and children’s health, heart and vascular studies and the aging brain. www.thebaltimorebanner.com/education/hi...
New cover slide for work in progress talk tomorrow #devbio #neuroscience 🧪🧠🌈
January 30, 2025 at 11:21 PM
New cover slide for work in progress talk tomorrow #devbio #neuroscience 🧪🧠🌈
An actual #microscopymonday in action! Beautiful #organoids packed full of neurons #neurobiology #neurodev 😍🧠🧪
January 27, 2025 at 7:01 PM
An actual #microscopymonday in action! Beautiful #organoids packed full of neurons #neurobiology #neurodev 😍🧠🧪
We are hiring! Looking for a research technician to join our team, preferably with some wet lab experience but not necessary. We welcome anyone with a willingness to learn! Applications can be submitted through jobs.weill.cornell.edu/job-invite/9...
Research Technician I
Research Technician I
jobs.weill.cornell.edu
January 10, 2025 at 1:56 PM
We are hiring! Looking for a research technician to join our team, preferably with some wet lab experience but not necessary. We welcome anyone with a willingness to learn! Applications can be submitted through jobs.weill.cornell.edu/job-invite/9...
Have some reading to do! Thanks @trayon.bsky.social for this list!
A selection of papers in 2024 associated with developmental timing & mammalian pausing.
🐭⌛️👤⏳
#EvoDevoTempo
1/n
🐭⌛️👤⏳
#EvoDevoTempo
1/n
December 29, 2024 at 1:12 PM
Have some reading to do! Thanks @trayon.bsky.social for this list!
Super happy to receive an R03 from the NIMH to continue our work on FOXP1 and further our understanding of its role during brain development 🧪🧠🦊
December 11, 2024 at 10:58 PM
Super happy to receive an R03 from the NIMH to continue our work on FOXP1 and further our understanding of its role during brain development 🧪🧠🦊
Had such a fun morning at UCLA. It was so nice to see old friends and meet new people and have the opportunity to present our work 🧪🧠
December 7, 2024 at 3:23 AM
Had such a fun morning at UCLA. It was so nice to see old friends and meet new people and have the opportunity to present our work 🧪🧠
Reposting this now I have a few more followers!
jobrxiv.org/job/weill-co...
The Pearson lab is looking for an enthusiastic post doc with experience in #mousemodels, #humancellculture, #organoid, #confocalmicroscopy and #transcriptomics. Experience in #metabolism an extra bonus!
jobrxiv.org/job/weill-co...
The Pearson lab is looking for an enthusiastic post doc with experience in #mousemodels, #humancellculture, #organoid, #confocalmicroscopy and #transcriptomics. Experience in #metabolism an extra bonus!
Post doc position in neural progenitor cell biology and metabolism.
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
jobrxiv.org
December 3, 2024 at 4:55 PM
Some post-holiday reading! 😍 🧪 🧠@derubeislab.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X
DDX3X is an X-linked RNA helicases that escapes X chromosome inactivation and is expressed at higher levels in female brains. Mutations in DDX3X are associated with intellectual disability (ID) and au...
www.biorxiv.org
December 1, 2024 at 9:49 PM
Some post-holiday reading! 😍 🧪 🧠@derubeislab.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...