Steven Sloan
@sloanlab.bsky.social
Neuroscientist. Glial Biologist. Astrocyte enthusiast. Neurodevelopmental lab at Emory University studying the role of glia in health and disease.
www.SloanLab.org
www.SloanLab.org
Excited to share an important new pre-print from the lab led by incredibly talented postdoc @maureenbiologies.bsky.social, a neurotoxicologist who came to the lab with an ambitious goal of understanding the consequences of toxicant exposure in human neurodevelopment. www.biorxiv.org/content/10.1...
August 21, 2025 at 8:10 PM
Excited to share an important new pre-print from the lab led by incredibly talented postdoc @maureenbiologies.bsky.social, a neurotoxicologist who came to the lab with an ambitious goal of understanding the consequences of toxicant exposure in human neurodevelopment. www.biorxiv.org/content/10.1...
I've been really hoping to see more manuscript threads here on 🦋, so here comes one!!! This is brand new work from the lab that took us in very unexpected directions and to exciting findings led by the amazing @emily-hill.bsky.social. Preprint here www.biorxiv.org/content/10.1...
and 🧵below:
and 🧵below:
June 30, 2025 at 6:26 PM
I've been really hoping to see more manuscript threads here on 🦋, so here comes one!!! This is brand new work from the lab that took us in very unexpected directions and to exciting findings led by the amazing @emily-hill.bsky.social. Preprint here www.biorxiv.org/content/10.1...
and 🧵below:
and 🧵below:
Reposted by Steven Sloan
Our lab's 1st paper, led by @fchrisbennett.bsky.social & @waisenberg.bsky.social. A decade thinking how to directly assess the impact of microglia replacement. Yrs of hard work. This kind of work is needed to expand brain disease care for kids & the vision for safer, more effective cell therapy.
Online now: Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
Hematopoietic stem cell transplant is the gold standard for treatment of globoid cell leukodystrophy, also called Krabbe disease. Aisenberg et al. define the molecular signature of disease-associated macrophages (globoid cells) and demonstrate that brain-specific high-efficiency macrophage replacement in the twitcher model of Krabbe disease improves neuropathology, macrophage dysfunction, and survival.
dlvr.it
April 30, 2025 at 9:20 PM
Our lab's 1st paper, led by @fchrisbennett.bsky.social & @waisenberg.bsky.social. A decade thinking how to directly assess the impact of microglia replacement. Yrs of hard work. This kind of work is needed to expand brain disease care for kids & the vision for safer, more effective cell therapy.
Trying my best to focus on some positive science content. We feel so grateful to have our work highlighted on the cover of @naturecellbiology.bsky.social!
This beautiful #astrocyte reconstructed from the raw data images used in the paper. Most of which are never typically seen! rdcu.be/d5ADz
This beautiful #astrocyte reconstructed from the raw data images used in the paper. Most of which are never typically seen! rdcu.be/d5ADz
February 18, 2025 at 12:07 PM
Trying my best to focus on some positive science content. We feel so grateful to have our work highlighted on the cover of @naturecellbiology.bsky.social!
This beautiful #astrocyte reconstructed from the raw data images used in the paper. Most of which are never typically seen! rdcu.be/d5ADz
This beautiful #astrocyte reconstructed from the raw data images used in the paper. Most of which are never typically seen! rdcu.be/d5ADz
This is our future! A PhD on its own is a roller coaster with little stability. These extra hurdles for some of our brightest scientists need to be eliminated--not exacerbated.
Fresh off the press by @thetransmitter.bsky.social on the uncertainties trainees are facing with diversity-based funding.
I’m thrilled to share a piece of my story & continue to be a champion for diversity.
Ty to the journalists & trainees for their work!
www.thetransmitter.org/funding/a-gu...
I’m thrilled to share a piece of my story & continue to be a champion for diversity.
Ty to the journalists & trainees for their work!
www.thetransmitter.org/funding/a-gu...
‘A gut punch:’ How U.S. neuroscience trainees are grappling with diversity-based funding flux
Ten trainees spoke with The Transmitter about how the precarious state of U.S. federal funding is affecting their research and career plans.
www.thetransmitter.org
February 14, 2025 at 9:02 PM
This is our future! A PhD on its own is a roller coaster with little stability. These extra hurdles for some of our brightest scientists need to be eliminated--not exacerbated.
New preprint! A really fun project spearheaded by amazing graduate student @christinaramelow.bsky.social and a collaboration with Srikant Rangaraju's group.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling
Deep molecular phenotyping of cells at transcriptomic and proteomic levels is an essential first step to understanding cellular contributions to development, aging, injury, and disease. Since proteome...
www.biorxiv.org
February 3, 2025 at 9:12 PM
New preprint! A really fun project spearheaded by amazing graduate student @christinaramelow.bsky.social and a collaboration with Srikant Rangaraju's group.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A great opportunity to join this special team! Details below
We're excited to announce that the Brain Organoid Hub is hiring! If you, or someone you know, has an interest in working with stem cells and brain organoids as a Research Specialist, please feel free to apply 🔬
www.linkedin.com/jobs/view/41...
www.linkedin.com/jobs/view/41...
Emory University hiring Research Specialist in Atlanta, GA | LinkedIn
Posted 5:54:49 PM. The Sloan, Andersen, and Birey Labs at Emory University are recruiting a motivated individual to…See this and similar jobs on LinkedIn.
www.linkedin.com
January 22, 2025 at 12:14 AM
A great opportunity to join this special team! Details below
Hi #neuroscience community! This is one of my favorite posts ever. In close collaboration with @liddelowsa.bsky.social and Ye Zhang, we've built a new tool that we are eager to share! www.webseq.net
WEBseq
share freely
www.webseq.net
January 15, 2025 at 4:21 PM
Hi #neuroscience community! This is one of my favorite posts ever. In close collaboration with @liddelowsa.bsky.social and Ye Zhang, we've built a new tool that we are eager to share! www.webseq.net
First 🦋 post! Very excited to share our lab's latest work exploring the shared and divergent aspects of human astrocyte development and glioblastoma. This effort spans many fields from developmental #glial biology to #stem cells and #tumor biology. rdcu.be/d5ADz A 🧵
Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma
Nature Cell Biology - Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with...
rdcu.be
January 8, 2025 at 5:13 PM
First 🦋 post! Very excited to share our lab's latest work exploring the shared and divergent aspects of human astrocyte development and glioblastoma. This effort spans many fields from developmental #glial biology to #stem cells and #tumor biology. rdcu.be/d5ADz A 🧵