Angelika Lampert
@lampertlab.bsky.social
sodium channels, pain, stem cell derived nociceptors, electrophysiology, sensory neuron subclasses and translational research. Professor for Neurophysiology at RWTH Aachen, Germany.
Reposted by Angelika Lampert
The review process will be overseen by JGP Associate Editors Teresa Giraldez (@giraldezt.bsky.social) and Jeanne Nerbonne, with Guest Editor and subject experts Angelika Lampert (@lampertlab.bsky.social), Hugues Abriel, and Rajesh Khanna (@khannalabuf.bsky.social) 👉 rupress.org/jgp/pages/ca...
November 5, 2025 at 9:45 PM
The review process will be overseen by JGP Associate Editors Teresa Giraldez (@giraldezt.bsky.social) and Jeanne Nerbonne, with Guest Editor and subject experts Angelika Lampert (@lampertlab.bsky.social), Hugues Abriel, and Rajesh Khanna (@khannalabuf.bsky.social) 👉 rupress.org/jgp/pages/ca...
⏰ Abstract deadline tomorrow! Join us in Grindelwald, Feb 4–6, 2026 Worldwide Sodium Channel Conference!
Robert Stewart (Harvard) talks on Nav1.8 inhibition & new Nav blockers for pain 💥Accepted abstracts → special issue @jgp.org👉 sodiumchannelconference2026.org
#WSCC26 #SodiumChannels #PainResearch
Robert Stewart (Harvard) talks on Nav1.8 inhibition & new Nav blockers for pain 💥Accepted abstracts → special issue @jgp.org👉 sodiumchannelconference2026.org
#WSCC26 #SodiumChannels #PainResearch
November 1, 2025 at 8:21 AM
⏰ Abstract deadline tomorrow! Join us in Grindelwald, Feb 4–6, 2026 Worldwide Sodium Channel Conference!
Robert Stewart (Harvard) talks on Nav1.8 inhibition & new Nav blockers for pain 💥Accepted abstracts → special issue @jgp.org👉 sodiumchannelconference2026.org
#WSCC26 #SodiumChannels #PainResearch
Robert Stewart (Harvard) talks on Nav1.8 inhibition & new Nav blockers for pain 💥Accepted abstracts → special issue @jgp.org👉 sodiumchannelconference2026.org
#WSCC26 #SodiumChannels #PainResearch
🎙️ Carol Ann Remme (Amsterdam UMC) joins #WSCC26 (Feb 4–6, 2026, Grindelwald, CH) to talk about cardiac sodium channels ❤️ and their role in cardiac physiology & disease.
🧠 Abstracts due Nov 2
🔗 sodiumchannelconference2026.org/WELCOME/
#NaV #ionchannels #cardiacphysiology #scienceconference
🧠 Abstracts due Nov 2
🔗 sodiumchannelconference2026.org/WELCOME/
#NaV #ionchannels #cardiacphysiology #scienceconference
October 30, 2025 at 8:50 AM
🎙️ Carol Ann Remme (Amsterdam UMC) joins #WSCC26 (Feb 4–6, 2026, Grindelwald, CH) to talk about cardiac sodium channels ❤️ and their role in cardiac physiology & disease.
🧠 Abstracts due Nov 2
🔗 sodiumchannelconference2026.org/WELCOME/
#NaV #ionchannels #cardiacphysiology #scienceconference
🧠 Abstracts due Nov 2
🔗 sodiumchannelconference2026.org/WELCOME/
#NaV #ionchannels #cardiacphysiology #scienceconference
🎙️ José Ángel Aibar, President of the Dravet Syndrome Foundation, joins #WSCC26 (Feb 4–6, 2026, Grindelwald 🇨🇭) to talk about advancing collaboration & discovery in Dravet syndrome.
🧠 Abstracts due Nov 2 – all published in a JGP special issue!
🔗 sodiumchannelconference2026.org/WELCOME/
🧠 Abstracts due Nov 2 – all published in a JGP special issue!
🔗 sodiumchannelconference2026.org/WELCOME/
October 29, 2025 at 10:10 AM
🎙️ José Ángel Aibar, President of the Dravet Syndrome Foundation, joins #WSCC26 (Feb 4–6, 2026, Grindelwald 🇨🇭) to talk about advancing collaboration & discovery in Dravet syndrome.
🧠 Abstracts due Nov 2 – all published in a JGP special issue!
🔗 sodiumchannelconference2026.org/WELCOME/
🧠 Abstracts due Nov 2 – all published in a JGP special issue!
🔗 sodiumchannelconference2026.org/WELCOME/
Reposted by Angelika Lampert
Voltage-gated sodium channels: Mechanisms, disease, and a growing research community. Hugues Abriel and Angelika Lampert (@lampertlab.bsky.social) introduce the Special Issue (rupress.org/jgp/search-r...) illustrating the richness and continuing momentum of this field. rupress.org/jgp/article/...
October 17, 2025 at 1:31 PM
Voltage-gated sodium channels: Mechanisms, disease, and a growing research community. Hugues Abriel and Angelika Lampert (@lampertlab.bsky.social) introduce the Special Issue (rupress.org/jgp/search-r...) illustrating the richness and continuing momentum of this field. rupress.org/jgp/article/...
Reposted by Angelika Lampert
This Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. Editorial by Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...
October 10, 2025 at 4:01 PM
This Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. Editorial by Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...
Reposted by Angelika Lampert
@jgp.org Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. From Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...
October 10, 2025 at 4:45 PM
@jgp.org Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. From Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...
Come to the second edition of the world wide sodium channel conference! Submit an abstract by September 26.
2nd #WSCC26 will take place in Grindelwald (Switzerland) 🚠 from 4th to 6th of February, 2026.
🌍 Join @lampertlab.bsky.social , @antoniospantazis.bsky.social, @khannalabuf.bsky.social, and others.
💡 Submit abstracts by the 26th of September, 2025:
lnkd.in/eDhPUVKd
💻 More info:
lnkd.in/eJw9pfMz
🌍 Join @lampertlab.bsky.social , @antoniospantazis.bsky.social, @khannalabuf.bsky.social, and others.
💡 Submit abstracts by the 26th of September, 2025:
lnkd.in/eDhPUVKd
💻 More info:
lnkd.in/eJw9pfMz
September 6, 2025 at 4:56 AM
Come to the second edition of the world wide sodium channel conference! Submit an abstract by September 26.
Reposted by Angelika Lampert
In this Viewpoint, Hull and @lampertlab.bsky.social explore the role of metaphors in the sodium channel fast inactivation mechanism-accessible to readers without a linguistics background. rupress.org/jgp/article/...
📙 In JGP Highlights Collection 2025: rupress.org/jgp/collecti...
#SGP2025
📙 In JGP Highlights Collection 2025: rupress.org/jgp/collecti...
#SGP2025
September 3, 2025 at 4:45 PM
In this Viewpoint, Hull and @lampertlab.bsky.social explore the role of metaphors in the sodium channel fast inactivation mechanism-accessible to readers without a linguistics background. rupress.org/jgp/article/...
📙 In JGP Highlights Collection 2025: rupress.org/jgp/collecti...
#SGP2025
📙 In JGP Highlights Collection 2025: rupress.org/jgp/collecti...
#SGP2025
Sodium channels and clinical pain: join the finale of worldwide sodium channel seminar series by Janneke Hoeijmakers on June 24! Still not enough of Nav research? Safe the date for the 2nd ww Nav channel conference Feb 4 to 6, 26 in Grindelwald CH⛰️. www.sodiumchannelseminars.org
June 18, 2025 at 8:11 PM
Sodium channels and clinical pain: join the finale of worldwide sodium channel seminar series by Janneke Hoeijmakers on June 24! Still not enough of Nav research? Safe the date for the 2nd ww Nav channel conference Feb 4 to 6, 26 in Grindelwald CH⛰️. www.sodiumchannelseminars.org
Metaphors shape how we communicate & understand science, from genetic blueprints to molecular gates. Hull and @lampertlab.bsky.social explore their role in the sodium channel fast inactivation mechanism-accessible to readers without a linguistics background. rupress.org/jgp/article/...
#IonChannels
#IonChannels
June 18, 2025 at 7:27 PM
Very happy that our science-literature synergism resulting from the worldwide sodium channel conference #WSCC24 in Grindelwald is now out. Ever thought about how the words you are using to describe your results shape how you approach your science? I hope you enjoy reading our article!
Using metaphorical considerations to benefit research on the sodium channel fast inactivation mechanism. New Viewpoint article from Peter Hull @fau.de and Angelika Lampert @lampertlab.bsky.social @rwth.bsky.social: rupress.org/jgp/article/...
#VoltageGatedNaChannels #Biophysics #IonChannels
#VoltageGatedNaChannels #Biophysics #IonChannels
June 18, 2025 at 7:26 PM
Very happy that our science-literature synergism resulting from the worldwide sodium channel conference #WSCC24 in Grindelwald is now out. Ever thought about how the words you are using to describe your results shape how you approach your science? I hope you enjoy reading our article!
Slow inactivation of the fast sodium channel will be the topic of our next worldwide sodium channel seminar by Shimon Marom Tuesday May 27th on "Adaptive, slow sodium channel inactivation: impacts on neuronal excitability".
www.sodiumchannelseminars.org for link and infos. 🧠 🎓
www.sodiumchannelseminars.org for link and infos. 🧠 🎓
May 21, 2025 at 11:05 AM
Slow inactivation of the fast sodium channel will be the topic of our next worldwide sodium channel seminar by Shimon Marom Tuesday May 27th on "Adaptive, slow sodium channel inactivation: impacts on neuronal excitability".
www.sodiumchannelseminars.org for link and infos. 🧠 🎓
www.sodiumchannelseminars.org for link and infos. 🧠 🎓
happening today, Tuesday 29th of April!
It will be turbulent in the next worldwide sodium channel seminar: @antoniospantazis.bsky.social will explain why "Even a single carbon atom matters: deadly and unexpected consequences of a Nav1.5 variant" Tuesday April 29th. Visit www.sodiumchannelseminars.org for link and infos. #sodiumchannel
April 29, 2025 at 12:28 PM
happening today, Tuesday 29th of April!
Reposted by Angelika Lampert
New paper blue-torial! On the surface, it's a new ⚡Nav1.5 #channelopathy causing 🫀 familial cardiac #arrhythmia. But our story has enough plot twists to rival MK Shyamalan!
www.jmcc-online.com/article/S002...
🧵 1/11
www.jmcc-online.com/article/S002...
🧵 1/11
Clinical and electrophysiological characterization of a SCN5A gain-of-function mutation associated with CPVT-like arrhythmia
The present study aimed to characterize the SCN5A variant I1333V, found in five families
with a history of suspected catecholaminergic polymorphic ventricular tachycardia
(CPVT). SCN5A encodes the por...
www.jmcc-online.com
April 13, 2025 at 10:59 AM
New paper blue-torial! On the surface, it's a new ⚡Nav1.5 #channelopathy causing 🫀 familial cardiac #arrhythmia. But our story has enough plot twists to rival MK Shyamalan!
www.jmcc-online.com/article/S002...
🧵 1/11
www.jmcc-online.com/article/S002...
🧵 1/11
It will be turbulent in the next worldwide sodium channel seminar: @antoniospantazis.bsky.social will explain why "Even a single carbon atom matters: deadly and unexpected consequences of a Nav1.5 variant" Tuesday April 29th. Visit www.sodiumchannelseminars.org for link and infos. #sodiumchannel
April 16, 2025 at 4:17 PM
It will be turbulent in the next worldwide sodium channel seminar: @antoniospantazis.bsky.social will explain why "Even a single carbon atom matters: deadly and unexpected consequences of a Nav1.5 variant" Tuesday April 29th. Visit www.sodiumchannelseminars.org for link and infos. #sodiumchannel
Reposted by Angelika Lampert
Our Center is a great place to work! If you are looking for a lab technician position, please check out our posting!
📢 We're Hiring! Join Our Team at the Center for Advanced Pain Studies!
✨ CAPS is looking for a research technician. If you are passionate about research and studying chronic pain or migraine, this is your opportunity.
🔗 Learn more and apply: UTD.link/2v7
✨ CAPS is looking for a research technician. If you are passionate about research and studying chronic pain or migraine, this is your opportunity.
🔗 Learn more and apply: UTD.link/2v7
March 12, 2025 at 5:11 PM
Our Center is a great place to work! If you are looking for a lab technician position, please check out our posting!
Nav1.7 structure and severe pain: join our next worldwide sodium channel seminar on March 25th by Goragot Wisedchaisri (Seattle, US) on the “Structural basis for severe pain caused by mutations in Nav1.7”
www.sodiumchannelseminars.org for link and infos. See you there!
#ionchannel #WSCS
www.sodiumchannelseminars.org for link and infos. See you there!
#ionchannel #WSCS
March 17, 2025 at 7:25 AM
Nav1.7 structure and severe pain: join our next worldwide sodium channel seminar on March 25th by Goragot Wisedchaisri (Seattle, US) on the “Structural basis for severe pain caused by mutations in Nav1.7”
www.sodiumchannelseminars.org for link and infos. See you there!
#ionchannel #WSCS
www.sodiumchannelseminars.org for link and infos. See you there!
#ionchannel #WSCS
Reposted by Angelika Lampert
Join us in Berlin in September! It is going to be a great meeting for those of you interested in neuropathic pain, itch and related conditions! #Painresearch #PainScience 🧪🧠
Time is Running out! Submit your poster abstract for #NeuPSIG2025 and present at the leading international pain meeting in Berlin this September. Submission Deadline: 3 March bit.ly/40r4Zz5 #PainScience #Neurology
February 25, 2025 at 2:23 PM
Join us in Berlin in September! It is going to be a great meeting for those of you interested in neuropathic pain, itch and related conditions! #Painresearch #PainScience 🧪🧠
Miriam Meisler will give our next #WWSC seminar on Feb 25th. Come and discuss Nav1.6 pathophysiology in epilepsy and treatment options: "Down-regulation of SCN8A by ASO or CRISPR-i prevents seizures in a GOF model".
Visit www.sodiumchannelseminar.org for info and link. See you there!
Visit www.sodiumchannelseminar.org for info and link. See you there!
February 12, 2025 at 7:03 PM
Miriam Meisler will give our next #WWSC seminar on Feb 25th. Come and discuss Nav1.6 pathophysiology in epilepsy and treatment options: "Down-regulation of SCN8A by ASO or CRISPR-i prevents seizures in a GOF model".
Visit www.sodiumchannelseminar.org for info and link. See you there!
Visit www.sodiumchannelseminar.org for info and link. See you there!
Reposted by Angelika Lampert
Commentary: Christian Jorgensen @jorlab123.bsky.social discusses new study from Elhanafy et al. (https://buff.ly/4haX9PQ) which shows how identical mutations in the voltage sensing domain of sodium channels can yield differential functional effects. https://buff.ly/4jpCRUD
#IonChannels
#IonChannels
January 23, 2025 at 6:33 PM
Commentary: Christian Jorgensen @jorlab123.bsky.social discusses new study from Elhanafy et al. (https://buff.ly/4haX9PQ) which shows how identical mutations in the voltage sensing domain of sodium channels can yield differential functional effects. https://buff.ly/4jpCRUD
#IonChannels
#IonChannels
Reposted by Angelika Lampert
Nociceptor sodium #ionchannels shape subthreshold phase, upstroke, and shoulder of action potentials | Journal of General Physiology @JGenPhysiol https://buff.ly/4hku7gH
#openaccess
#openaccess
January 29, 2025 at 11:39 AM
Nociceptor sodium #ionchannels shape subthreshold phase, upstroke, and shoulder of action potentials | Journal of General Physiology @JGenPhysiol https://buff.ly/4hku7gH
#openaccess
#openaccess
1/5 Are you interested in the role of Nav1.9 in AP generation? And what do all the other #sodiumchannels do in the nociceptor? In a study led by the MD student Phil Köster in the lab, we performed manual patch clamp on all Navs known to be expressed in sensory neurons. Nav1.1,2,3,5,6,7,8,9.
Köster, Stiehl, @lampertlab.bsky.social and colleagues characterize eight sodium channel subtypes relevant to #nociception and use a computer model to simulate the response of two types of nociceptive nerve fibers. https://buff.ly/4hku7gH
#Biophysics #Neuroscience #IonChannels
#Biophysics #Neuroscience #IonChannels
January 30, 2025 at 8:49 PM
1/5 Are you interested in the role of Nav1.9 in AP generation? And what do all the other #sodiumchannels do in the nociceptor? In a study led by the MD student Phil Köster in the lab, we performed manual patch clamp on all Navs known to be expressed in sensory neurons. Nav1.1,2,3,5,6,7,8,9.
Reposted by Angelika Lampert
and a 3rd BOOM! for today: www.biorxiv.org/content/10.1... Again on VGNaCs. Navs enter the PROTAC era!! Well done Alex Chamessian and @robgereau.bsky.social
Small molecule-mediated targeted protein degradation of voltage-gated sodium channels involved in pain
The voltage-gated sodium channels (VGSC) NaV1.8 and NaV1.7 (NaVs) have emerged as promising and high-value targets for the development of novel, non-addictive analgesics to combat the chronic pain epi...
www.biorxiv.org
January 22, 2025 at 12:31 PM
and a 3rd BOOM! for today: www.biorxiv.org/content/10.1... Again on VGNaCs. Navs enter the PROTAC era!! Well done Alex Chamessian and @robgereau.bsky.social
Reposted by Angelika Lampert
Köster, Stiehl, @lampertlab.bsky.social and colleagues characterize eight sodium channel subtypes relevant to #nociception and use a computer model to simulate the response of two types of nociceptive nerve fibers. https://buff.ly/4hku7gH
#Biophysics #Neuroscience #IonChannels
#Biophysics #Neuroscience #IonChannels
January 21, 2025 at 5:17 PM
Köster, Stiehl, @lampertlab.bsky.social and colleagues characterize eight sodium channel subtypes relevant to #nociception and use a computer model to simulate the response of two types of nociceptive nerve fibers. https://buff.ly/4hku7gH
#Biophysics #Neuroscience #IonChannels
#Biophysics #Neuroscience #IonChannels