Hsiao-Tuan Chao (赵孝端), MD PhD
@htchaolab.bsky.social
Neuroscientist+Child Neurologist. McNair Scholar #RareDisease, #neurogenetics, inhibition/circuits, #autism, #epilepsy, & brain disorders. RT≠endorse.
Pinned
🚨Proud mentor alert!🚨Congratulations to rising star 🌟 @jeff-kuerbitz.bsky.social in Child Neurology & neurogenetics @bcmhouston.bsky.social for receiving the competitive NeuralCODR fellowship @houstonmethodist.bsky.social! Stellar chalk talk! Kudos! 👏👏👏 #DuncanNRI #cerebellum #autism #rarediseases
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
Turns out, two of pain’s most famous messengers — Substance P and CGRPα — might not be so essential after all. Mice missing both still felt pain just fine, challenging decades of assumptions about how pain signals travel.
buff.ly/ypISrtx
buff.ly/ypISrtx
April 19, 2025 at 3:21 AM
Turns out, two of pain’s most famous messengers — Substance P and CGRPα — might not be so essential after all. Mice missing both still felt pain just fine, challenging decades of assumptions about how pain signals travel.
buff.ly/ypISrtx
buff.ly/ypISrtx
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
www.cnn.com
April 9, 2025 at 11:30 AM
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
11 of about 55 PIs terminated at NINDS yesterday, with downstream effects for all of us in terms of the lost research into neurological disease and stroke. 1/ www.wired.com/story/doctor...
Doctor Behind Award-Winning Parkinson’s Research Among Scientists Purged From NIH
Leading scientists at the National Institutes of Health, the US’s leading medical research agency, were swept up Tuesday in the Trump administration’s latest firing blitz.
www.wired.com
April 2, 2025 at 10:20 AM
11 of about 55 PIs terminated at NINDS yesterday, with downstream effects for all of us in terms of the lost research into neurological disease and stroke. 1/ www.wired.com/story/doctor...
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
Neuroscientists studying autism have missed a crucial fact - the condition looks different in boys and girls especially when it comes to the social brain.
A revolutionary new understanding of autism in girls
By studying the brains of autistic girls, we now know the condition presents differently in them than in boys, suggesting that huge numbers of women have gone undiagnosed
www.newscientist.com
April 2, 2025 at 12:08 PM
Neuroscientists studying autism have missed a crucial fact - the condition looks different in boys and girls especially when it comes to the social brain.
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
New pooled libraries available from the @alejofraticelli.bsky.social lab! These plasmid libraries can be used by scientists to produce lentiviral barcoding particles to barcode mammalian cells for clonal and state-fate analysis, using single-cell RNA sequencing
www.addgene.org/pool...
www.addgene.org/pool...
April 2, 2025 at 1:00 PM
New pooled libraries available from the @alejofraticelli.bsky.social lab! These plasmid libraries can be used by scientists to produce lentiviral barcoding particles to barcode mammalian cells for clonal and state-fate analysis, using single-cell RNA sequencing
www.addgene.org/pool...
www.addgene.org/pool...
🚨Proud mentor alert!🚨Congratulations to rising star 🌟 @jeff-kuerbitz.bsky.social in Child Neurology & neurogenetics @bcmhouston.bsky.social for receiving the competitive NeuralCODR fellowship @houstonmethodist.bsky.social! Stellar chalk talk! Kudos! 👏👏👏 #DuncanNRI #cerebellum #autism #rarediseases
April 2, 2025 at 1:29 AM
🚨Proud mentor alert!🚨Congratulations to rising star 🌟 @jeff-kuerbitz.bsky.social in Child Neurology & neurogenetics @bcmhouston.bsky.social for receiving the competitive NeuralCODR fellowship @houstonmethodist.bsky.social! Stellar chalk talk! Kudos! 👏👏👏 #DuncanNRI #cerebellum #autism #rarediseases
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
All scientists, regardless of their discipline or location, are potential targets for online hate. But there are things you can do to protect yourself, and resources that can help. Nature provides five steps to get started. #Academicsky 🧪
Stay safe from online hate with these five tips
In this era of anti-science activism, it‘s wise to take steps to protect your research and reputation in the digital realm.
go.nature.com
March 27, 2025 at 1:13 AM
All scientists, regardless of their discipline or location, are potential targets for online hate. But there are things you can do to protect yourself, and resources that can help. Nature provides five steps to get started. #Academicsky 🧪
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
You can't remember your infancy, but does that mean that babies don't form memories? If only we could scan their brains to learn what they can't yet tell us. Well, actually...
Check out this NPR segment on the amazing work of @tristansyates.bsky.social and my friend & colleague Nick Turk-Browne!
Check out this NPR segment on the amazing work of @tristansyates.bsky.social and my friend & colleague Nick Turk-Browne!
Why don't we remember being babies? Brain scans reveal new clues
Why can't we remember when we were babies? Scientists who scanned infants' brains found that they do make memories. The findings suggest these memories may still exist, but are inaccessible to us.
www.npr.org
March 26, 2025 at 8:59 PM
You can't remember your infancy, but does that mean that babies don't form memories? If only we could scan their brains to learn what they can't yet tell us. Well, actually...
Check out this NPR segment on the amazing work of @tristansyates.bsky.social and my friend & colleague Nick Turk-Browne!
Check out this NPR segment on the amazing work of @tristansyates.bsky.social and my friend & colleague Nick Turk-Browne!
Raising awareness on February 28, 2025 Rare Disease Day for the 300 million people with #rarediseases and their families to find answers and promote positive change! @bcmhouston.bsky.social @bcmgenetics.bsky.social
February 28, 2025 at 1:24 PM
Raising awareness on February 28, 2025 Rare Disease Day for the 300 million people with #rarediseases and their families to find answers and promote positive change! @bcmhouston.bsky.social @bcmgenetics.bsky.social
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
We're tracking measles cases across Texas amid an outbreak that has prompted health officials to issue warnings about the highly contagious respiratory illness. www.houstonchronicle.com/projects/202...
Tracking Texas' biggest measles outbreak in 30 years: Cases, vaccine rates
Gaines County is the epicenter of the current measles outbreak. It also has the highest share of students who received vaccine exemptions for nonmedical reasons.
www.houstonchronicle.com
February 25, 2025 at 9:34 PM
We're tracking measles cases across Texas amid an outbreak that has prompted health officials to issue warnings about the highly contagious respiratory illness. www.houstonchronicle.com/projects/202...
Congrats to BCM medical students Melina Corriveau & Joshua Korb for leading a great team of collaborators in identifying MEF2C-AS1 and #chromothripsis in 5q14.3 microdeletion syndrome. Providing key answers for #rarediseases #epilepsy 👏👏@bcmgenetics.bsky.social @bcmhouston.bsky.social
Rare #chromosome reshuffling leads to severe complex form of #epilepsy. Dr. HT Chao @htchaolab.bsky.social explains the findings. @bcmhouston.bsky.social @bcmgenetics.bsky.social #chromothripsis blogs.bcm.edu/2025/02/18/f...
Rare chromosome reshuffling leads to severe complex form of epilepsy
Although it's more commonly found in cancer, chromosome reshuffling is increasingly identified in neurodevelopmental disorders.
blogs.bcm.edu
February 24, 2025 at 11:01 PM
Congrats to BCM medical students Melina Corriveau & Joshua Korb for leading a great team of collaborators in identifying MEF2C-AS1 and #chromothripsis in 5q14.3 microdeletion syndrome. Providing key answers for #rarediseases #epilepsy 👏👏@bcmgenetics.bsky.social @bcmhouston.bsky.social
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
👩🔬 International Day of Women and Girls in Science
On this International Day of Women and Girls in Science, we honour the incredible contributions of women shaping the future of science.
#WomenInScience #GirlsInSTEM #WomenInSTEM #STEMinspiration #BreakingBarriers #STEMHeroes #WomenInResearch
On this International Day of Women and Girls in Science, we honour the incredible contributions of women shaping the future of science.
#WomenInScience #GirlsInSTEM #WomenInSTEM #STEMinspiration #BreakingBarriers #STEMHeroes #WomenInResearch
February 11, 2025 at 12:00 PM
👩🔬 International Day of Women and Girls in Science
On this International Day of Women and Girls in Science, we honour the incredible contributions of women shaping the future of science.
#WomenInScience #GirlsInSTEM #WomenInSTEM #STEMinspiration #BreakingBarriers #STEMHeroes #WomenInResearch
On this International Day of Women and Girls in Science, we honour the incredible contributions of women shaping the future of science.
#WomenInScience #GirlsInSTEM #WomenInSTEM #STEMinspiration #BreakingBarriers #STEMHeroes #WomenInResearch
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
The National Institutes of Health plans to severely cut the percentage of its grant money that can be used for overhead costs rather than research.
NIH slashes overhead payments for research, sparking outrage
Move to cut indirect cost rate to 15% could cost universities billions of dollars
scim.ag
February 8, 2025 at 2:50 AM
The National Institutes of Health plans to severely cut the percentage of its grant money that can be used for overhead costs rather than research.
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
Here is the hastily prepared script I just read to my reps after introducing myself:
February 8, 2025 at 1:48 AM
Here is the hastily prepared script I just read to my reps after introducing myself:
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:18 AM
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
January 25, 2025 at 9:25 PM
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
As trust in medicine declines and vaccine hesitancy spreads, doctors are changing how they talk about lifesaving childhood shots.
Pediatricians Try New Tactics To Win Over Vaccine Skeptical Parents
As trust in medicine declines and vaccine hesitancy spreads, doctors are changing how they talk about lifesaving childhood shots.
www.nytimes.com
January 24, 2025 at 6:42 PM
As trust in medicine declines and vaccine hesitancy spreads, doctors are changing how they talk about lifesaving childhood shots.
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
And the funding announcement for diversity supplements now has been updated to expire today. Supplements are so important to the careers of junior scientists. This is crushing for post docs and early career faculty
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
January 24, 2025 at 4:46 PM
And the funding announcement for diversity supplements now has been updated to expire today. Supplements are so important to the careers of junior scientists. This is crushing for post docs and early career faculty
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
#NIH #NINDS paylines are at 8% for fiscal 2025. Tough year is due to increased research costs and federal budget uncertainty for FY 2025. Director's message here. Worth reading. www.ninds.nih.gov/news-events/...
Featured Director's Message
www.ninds.nih.gov
November 24, 2024 at 9:12 PM
#NIH #NINDS paylines are at 8% for fiscal 2025. Tough year is due to increased research costs and federal budget uncertainty for FY 2025. Director's message here. Worth reading. www.ninds.nih.gov/news-events/...
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
This is one of the nearly 800 papers that I found during a study in which I scanned over 20,000 papers for such image duplications. About half of these papers are now corrected or retracted.
The study is published here:
journals.asm.org/doi/10.1128/...
The study is published here:
journals.asm.org/doi/10.1128/...
November 25, 2024 at 12:48 AM
This is one of the nearly 800 papers that I found during a study in which I scanned over 20,000 papers for such image duplications. About half of these papers are now corrected or retracted.
The study is published here:
journals.asm.org/doi/10.1128/...
The study is published here:
journals.asm.org/doi/10.1128/...
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
Neural Guidance of Lymphatics
#SchwannCell CXCL12⏫ Sprouting/Patterning of CXCR4+ #LymphaticEndothelialCell
Prox1-CreERT2:Cxcr4f/f🐭
⬇️ Lymphatic Valve formation
⬇️ VEGF-C-induced #Lymphangiogenesis
Xiaolei Liu lab Development 2024 @biologists.bsky.social
journals.biologists.com/dev/article-...
#SchwannCell CXCL12⏫ Sprouting/Patterning of CXCR4+ #LymphaticEndothelialCell
Prox1-CreERT2:Cxcr4f/f🐭
⬇️ Lymphatic Valve formation
⬇️ VEGF-C-induced #Lymphangiogenesis
Xiaolei Liu lab Development 2024 @biologists.bsky.social
journals.biologists.com/dev/article-...
November 24, 2024 at 8:31 PM
Neural Guidance of Lymphatics
#SchwannCell CXCL12⏫ Sprouting/Patterning of CXCR4+ #LymphaticEndothelialCell
Prox1-CreERT2:Cxcr4f/f🐭
⬇️ Lymphatic Valve formation
⬇️ VEGF-C-induced #Lymphangiogenesis
Xiaolei Liu lab Development 2024 @biologists.bsky.social
journals.biologists.com/dev/article-...
#SchwannCell CXCL12⏫ Sprouting/Patterning of CXCR4+ #LymphaticEndothelialCell
Prox1-CreERT2:Cxcr4f/f🐭
⬇️ Lymphatic Valve formation
⬇️ VEGF-C-induced #Lymphangiogenesis
Xiaolei Liu lab Development 2024 @biologists.bsky.social
journals.biologists.com/dev/article-...
Reposted by Hsiao-Tuan Chao (赵孝端), MD PhD
A few days ago, the journal eLife published a self-study on the first year of its new publishing model, and it is well worth a look. Here are some notes based on my own experience with the journal as author and reviewing editor: markusmeister.com/2024/03/17/a....
Thousands of authors have put their trust in our vision for publishing.
Today, we look back at the first year of our new model in numbers.
elifesciences.org/inside-elife...
Today, we look back at the first year of our new model in numbers.
elifesciences.org/inside-elife...
March 17, 2024 at 10:52 PM
A few days ago, the journal eLife published a self-study on the first year of its new publishing model, and it is well worth a look. Here are some notes based on my own experience with the journal as author and reviewing editor: markusmeister.com/2024/03/17/a....