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graingerlab.bsky.social
Grainger Lab
@graingerlab.bsky.social
Bacterial chromosome biology, gene expression, pathogenicity... and football.

www.graingerlab.com
Our lab is offering 3 PhD projects this year across 3 different topics: antibiotic resistance mechanisms, evolution of pathogenic bacteria, and fundamental mechanisms of gene regulation.

www.findaphd.com/phds/?Keywor...
grainger birmingham PhD Projects, Programmes & Scholarships - 3 PhDs Listed
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
www.findaphd.com
October 7, 2025 at 3:53 PM
@danielabarilla.bsky.social kicking off #BioPhyChrom2025 - a fantastic turn out too...
September 16, 2025 at 10:52 AM
Reposted by Grainger Lab
'We show that the VqmAj homologs can indeed detect (host autoinducer) DPO and, in response, activate the lytic pathway. Our observation indicates that jVP882 is a member of a large family of globally-dispersed quorum-sensing-responsive temperate phages.'
www.biorxiv.org/content/10.1...
A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species
Temperate phages oscillate between lysogeny, a genomic maintenance state within a bacterial host, and lytic replication, in which the host is killed, and newly made phage particles are released. Succe...
www.biorxiv.org
August 1, 2025 at 12:28 PM
Reposted by Grainger Lab
📢 Dear lovers of prokaryotic chromosomes:
Registration for the Biology & Physics of Chromosomes meeting has been extended until 7 August ⏳.
Join us!
@biophychrom.bsky.social
@danielabarilla.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@biochemsoc.bsky.social
#microsky
July 30, 2025 at 10:20 AM
Talk slots full but we can take late breaking poster abstracts until August 7th. Hope to see you in York to hear about your chromosome story 🧬🦠🧫

www.eventsforce.net/biochemsoc/f...

@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
July 25, 2025 at 12:14 PM
Reposted by Grainger Lab
How are bacterial transport machineries regulated by external cues? @brochadolab.bsky.social &co identify environmental chemicals that regulate #transporter transcription, identifying the TF Rob as a key modulator of #EffluxPump expression in #Ecoli #AMR @plosbiology.org 🧪 plos.io/46pUM9Q
July 23, 2025 at 9:20 AM
Reposted by Grainger Lab
Just few days left to register for this chromosome biology fête! 🧬🧬🧬

⏳📆 16 July

www.eventsforce.net/biochemsoc/f...

@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
July 14, 2025 at 12:47 PM
Reposted by Grainger Lab
Chromosome Enthusiasts, join us at The Biology & Physics of Prokaryotic Chromosomes 🧬! Friendly community, fantastic speakers line-up, grant writing session for ECRs. Early-bird deadline approaching soon.
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biophychrom.bsky.social
June 11, 2025 at 10:53 AM
Reposted by Grainger Lab
Reposted by Grainger Lab
May 15, 2025 at 8:00 PM
Reposted by Grainger Lab
Fascinating new PLoS Biology paper from George Schaible et al in the Hatzenpichler Lab at Montana State

“𝘈𝘴 𝘵𝘩𝘦 𝘰𝘯𝘭𝘺 𝘦𝘹𝘢𝘮𝘱𝘭𝘦 𝘰𝘧 𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘢 𝘵𝘩𝘢𝘵 𝘦𝘹𝘩𝘪𝘣𝘪𝘵 𝘰𝘣𝘭𝘪𝘨𝘢𝘵𝘦 𝘮𝘶𝘭𝘵𝘪𝘤𝘦𝘭𝘭𝘶𝘭𝘢𝘳𝘪𝘵𝘺, 𝘔𝘔𝘉 𝘱𝘳𝘰𝘷𝘪𝘥𝘦 𝘢𝘯 𝘪𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘵 𝘦𝘹𝘢𝘮𝘱𝘭𝘦 𝘰𝘧 𝘱𝘰𝘴𝘴𝘪𝘣𝘭𝘦 𝘮𝘦𝘤𝘩𝘢𝘯𝘪𝘴𝘮𝘴 𝘣𝘦𝘩𝘪𝘯𝘥 𝘵𝘩𝘪𝘴 𝘱𝘳𝘰𝘧𝘰𝘶𝘯𝘥 𝘴𝘵𝘦𝘱 𝘪𝘯 𝘭𝘪𝘧𝘦’𝘴 𝘦𝘷𝘰𝘭𝘶𝘵𝘪𝘰𝘯𝘢𝘳𝘺 𝘩𝘪𝘴𝘵𝘰𝘳𝘺 𝘰𝘯 𝘌𝘢𝘳𝘵𝘩”
These Tiny Magnetic Bacteria Act Like a Single Body – And Could Explain the Origins of Complex Life
Tiny magnetic bacteria that live in tightly bound groups are showing scientists how life might have evolved complex, multicellular forms. These rare bacteria can’t survive alone – they depend on one a...
scitechdaily.com
April 9, 2025 at 11:44 AM
Reposted by Grainger Lab
We loved being back on campus for Master's hour on team working! @unibirmingham.bsky.social

The students created content to highlight the excellent research from one of our customers! It's all about the Long Reads 👀 @graingerlab.bsky.social @fozzz21.bsky.social @imibirmingham.bsky.social #MicroSky
February 5, 2025 at 4:52 PM
Reposted by Grainger Lab
Super excited to share the peer-reviewed version of the KorAB paper. Amazing to work such talented collaborators and thanks to the reviewers for making the work even better!
www.nature.com/articles/s41...
KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid - Nature Microbiology
Structural and single-molecule analyses show the CTPase, KorB, is a sliding DNA clamp that interacts with a clamp-locking protein KorA to inhibit gene expression over distances of more than 1 kb in th...
www.nature.com
January 23, 2025 at 11:08 AM
If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)
January 21, 2025 at 7:49 PM
Reposted by Grainger Lab
2x professorships available in Manchester Institute of Biotechnology including in Microbial Engineering area (broadly defined to include microbiomes, environmental biotech etc) — join us!
www.jobs.manchester.ac.uk/Job/JobDetai...
Chair Appointments within Manchester Institute of Biotechnology:Manchester Institute of Biotechnology
www.jobs.manchester.ac.uk
November 29, 2024 at 10:01 AM
Reposted by Grainger Lab
November 28, 2024 at 12:58 PM
PhD projects available in our lab all listed in the below link. All focus on bacterial gene regulation, in the context of basic understanding, disease, or antibiotic resistance. Deadlines in January...

www.findaphd.com/phds/?Keywor...
grainger birmingham PhD Projects, Programmes & Scholarships
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
www.findaphd.com
November 28, 2024 at 3:13 PM