Vicky Lioy
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vslioy.bsky.social
Vicky Lioy
@vslioy.bsky.social
230 followers 160 following 72 posts
Team leader @i2bcparissaclay.bsky.social #GenomeBiologyI2BC. Interested in bacterial chromosome and chromatin organization.
I2BC Science: https://www.scoop.it/u/institut-de-biologie-integrative-de-la-cellule/curated-scoops
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vslioy.bsky.social
Vicky Lioy @vslioy.bsky.social · Jul 30
📢 Dear lovers of prokaryotic chromosomes:
Registration for the Biology & Physics of Chromosomes meeting has been extended until 7 August ⏳.
Join us!
@biophychrom.bsky.social
@danielabarilla.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@biochemsoc.bsky.social
#microsky
Reposted by Vicky Lioy
I am very pleased to share that our database of prokaryotic and viral histones, ProHistoneDB, is now available online at prohistonedb.org. Please also see the accompanying article in J Mol Biol: doi.org/10.1016/j.jm...
ProHistoneDB
prohistonedb.org
January 16, 2026 at 8:47 AM
Reposted by Vicky Lioy
juliebiteenlab.bsky.social
Bacteria are amazing! The abundant Dps protein binds and protects DNA in stationary-phase cells with minimal effect on chromosome accessibility, dynamics, and organization. Now in NAR doi.org/10.1093/nar/...; I'm really proud of our multidisciplinary team led by Lauren, Lindsay, and Xiaofeng, et al.
January 16, 2026 at 1:32 PM
Reposted by Vicky Lioy
anne-lopes.bsky.social
Fresh news on de novo genes! Happy to present our latest work published in Nature communications: www.nature.com/articles/s41...

Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
January 11, 2026 at 7:43 PM
vslioy.bsky.social
Le CNRS met en avant notre article publié dans @natcomms.nature.com
Un grand merci à toutes et tous pour ce beau projet mené en collaboration avec #MKortebi @mickaelbourge.bsky.social @imagerie-gif.bsky.social #NGSFacilityI2BC, #E.vanDijk, @bury-mone.bsky.social, #CDorman et #FBoccard
January 11, 2026 at 2:24 PM
Reposted by Vicky Lioy
alfmicrobe.bsky.social
After 4 years of joint effort of my Lab and Dr. Llorente Team we took for first time SCRaMbLE to a bacterial system! This allowed us to massively reordered the main chromosome of Vibrio natriegens!

biorxiv.org/content/10.6...
Here's a 🧵
Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change
The ability to generate genomic diversity expands opportunities for understanding and engineering biology. Here, we demonstrate on-demand generation of diversity in bacterial genome configurations and...
biorxiv.org
January 8, 2026 at 8:25 PM
Reposted by Vicky Lioy
aurelepiazza.bsky.social
SMC and recombination enthusiasts: we updated our work describing the loop extrusion properties of budding yeast condensin and its function in biasing donor usage for mating-type switching. Lots of cool new data, check it out!
www.biorxiv.org/content/10.1...
January 6, 2026 at 6:58 AM
vslioy.bsky.social
White start to the year. Happy 2026 to everyone!
@i2bcparissaclay.bsky.social
January 6, 2026 at 12:05 PM
vslioy.bsky.social
Today was the last scientific council of #GenomeBiologyi2bc. Thank you @betermieri2bc.bsky.social, #Julie_Soutourina and @phbouloc.bsky.social , for your support and for creating such a great scientific environment.
December 16, 2025 at 7:07 PM
vslioy.bsky.social
Nos travaux de recherche mis en avant dans Le Journal du CNRS !😀 @i2bcparissaclay.bsky.social
cnrs-paris-saclay.bsky.social CNRS à Paris-Saclay @cnrs-paris-saclay.bsky.social · Dec 11
🦠 Comment Salmonella déclenche-t-elle l’infection ? Le projet SaDi, mené à l'I2BC, révèle que l’architecture 3D de son génome orchestre l’activation des gènes de virulence.
✅ Une piste prometteuse pour déjouer l’antibiorésistance et l'infection.

▶️ lejournal.cnrs.fr/nos-blogs/fo...
Image d'illustration Crédit : © AdobeStock - Giovanni Cancemi
December 15, 2025 at 8:37 AM
vslioy.bsky.social
Open FSEP position in our team 📣
Nous recrutons un/e Ingénieur/e d’étude en biologie.
Profil : être titulaire d’un poste permanent au CNRS (IE) et avoir envie d’étudier la chromatine bactérienne 😉
Date limite : jeudi 15 janvier.
Détails et candidature ici :
mobiliteinterne.cnrs.fr/ords/afip/ow...
Détails de la fonction choisie
mobiliteinterne.cnrs.fr
December 8, 2025 at 12:52 PM
vslioy.bsky.social
What a wonderful week in Japan! 🇯🇵
Many thanks to Kazutoshi Kasho and Prof. Oshima for inviting me to #MBSJ2025.
Special thanks to @naomichitakemata.bsky.social and Shogo Ozaki for organising such a great satellite symposium.
It was truly a pleasure discussing science with all of you.
December 6, 2025 at 2:56 AM
Reposted by Vicky Lioy
danielabarilla.bsky.social
New exciting work on genome segregation in Haloferax by @premrajka.bsky.social and @bramkamplab.bsky.social group. 🧬<>🧬
biorxiv-microbiol.bsky.social bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Nov 19
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1
November 19, 2025 at 10:06 PM
Reposted by Vicky Lioy
danielabarilla.bsky.social
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social

www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects. High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.
November 9, 2025 at 5:20 PM
Reposted by Vicky Lioy
odedrechavi.bsky.social
IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇
November 6, 2025 at 2:49 PM
vslioy.bsky.social
🎉🥳👏Congratulations to Olivier and to the consortium. Excellent results will come to light soon in the #GenomeBiologyI2BC Department.
onamy.bsky.social Olivier Namy 🧬🧪 @onamy.bsky.social · Nov 6
I am very proud to announce that our team has received an ERC synergy grant from @erc.europa.eu. A wonderful recognition of a truly collaborative effort with friends (Julius Lukes, Leos Valasek and Mark Osborn). Excited to begin this journey at @i2bcparissaclay.bsky.social @cnrs.fr
erc.europa.eu European Research Council (ERC) @erc.europa.eu · Nov 6
The newly announced ERC Synergy Grant includes research on:

✴️ genetic drug design
✴️ the Big Bang's first microseconds
✴️ crowd movement
✴️ nature-society interactions

👉 buff.ly/ZQhLp4h

Congrats to the 66 awarded research teams!

#FrontierResearch
November 6, 2025 at 4:52 PM
Reposted by Vicky Lioy
gemma-langridge.bsky.social
🚨 Another funded PhD alert🚨

We are recruiting again! For a PhD student to start with us in the @langridgelab.bsky.social October 2026 - please share 👀

If you are interested in foodborne pathogens, public health and phage, look no further 🦠🏥🧬

➡️ tinyurl.com/3zvavp2t ⬅️

Apply by 6 Jan 2026 🗓️
October 28, 2025 at 1:17 PM
vslioy.bsky.social
#qed seems to be a new AI tool that could change the way we review (and write!) papers. Let’s try it!
odedrechavi.bsky.social Oded Rechavi @odedrechavi.bsky.social · Oct 15
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 25, 2025 at 10:56 PM
Reposted by Vicky Lioy
zeynepbaharoglu.bsky.social
Nucleoid structure and dynamics influence natural chromosomal transformation in Bacillus subtilis: the role of EbfC url: academic.oup.com/nar/article/...
Nucleoid structure and dynamics influence natural chromosomal transformation in Bacillus subtilis: the role of EbfC
Abstract. Natural chromosomal transformation (NCT) in Bacillus subtilis requires RecA and its accessory proteins including RecX and RecD2. Inactivation of
academic.oup.com
October 25, 2025 at 12:10 PM
vslioy.bsky.social
Another new team at #GenomeBiologyI2BC. Congratulations @cecilecourret.bsky.social
cecilecourret.bsky.social Cécile Courret @cecilecourret.bsky.social · Oct 24
I'm thrilled to announce that I’m opening my own research team in the Department of Genome Biology at I2BC @i2bcparissaclay.bsky.social ! #ATIP-Avenir
Very excited to start this new adventure! www.i2bc.paris-saclay.fr/equipe-intra...
Equipe Courret – Institute for Integrative Biology of the Cell
www.i2bc.paris-saclay.fr
October 24, 2025 at 10:29 PM
vslioy.bsky.social
Kicking off day two at the Spatial Organization of Biological Functions meeting at ICTS Bangalore! The first day was fascinating! #SOBF2025
October 22, 2025 at 4:23 AM
Reposted by Vicky Lioy
gruberlab.bsky.social
How do SMC complexes load onto DNA to get ready for loop extrusion?

@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️.

Check out the new paper: www.cell.com/molecular-ce...
October 9, 2025 at 2:43 PM
Reposted by Vicky Lioy
chloegirard.bsky.social
🚨 First pre-print from my team !!

TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !
The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis). In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres). In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).
October 1, 2025 at 8:31 AM
Reposted by Vicky Lioy
lalouxlab.bsky.social
📝New preprint! #MicroSky

🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.

🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.

www.biorxiv.org/content/10.1...
Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle
The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...
www.biorxiv.org
September 25, 2025 at 7:12 AM
Reposted by Vicky Lioy
emmabeansworth.bsky.social
The @yorkmuseumstrust.bsky.social's Hospitium was such a lovely location for the @biochemsoc.bsky.social #BioPhyChrom2025 conference dinner. Gorgeous gardens, fabulous food & captivating conversations

Thank you to the organisers for creating a great program & friendly interdisciplinary environment
September 19, 2025 at 9:42 AM
vslioy.bsky.social
This also happened at #BioPhyChrom2025, congratulations @ceesdekker.bsky.social

@danielabarilla.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
ceesdekker.bsky.social Cees Dekker @ceesdekker.bsky.social · Sep 19
As in so many ways I very much still feel like a novice student in exploring biology, I am very grateful and proud for this Award of the Biochemical Society 'for significant achievements in nanoscale molecular biology, especially the contribution to developing methodologies'.
biochemsoc.bsky.social Biochemical Society @biochemsoc.bsky.social · Sep 19
Congratulations to Cees Dekker @ceesdekker.bsky.social who showcased his work on single-molecule biophysics studies of DNA loop extrusion in his 2026 #BiochemAward Lecture for Significant Breakthrough or Achievement! We hope everyone enjoyed Prokaryotic Chromosomes VII!
September 19, 2025 at 6:31 PM