COVID Chronicles
@covidchronicles.bsky.social
Chronicling my journey through purgatory, graphically. Former athlete/composer/writer/woodworker. Saddled with debilitating COVID-induced metabolic dysfunction since Nov 2022. #LongCOVID #LC #MECFS #PEM #SickJokes
Pinned
Day 124 - Not sure how to deal with the poop emoji on my head. 'Brain fog' sounds light and fluffy, but this shit's heavier than lead.
#BrainFog #DailySlog #LongCOVID #COVIDSky #LC #MECFS #PEM
["But you still managed to make this, didn't you?" Yes. Yes, I did. And it only took me six days]
#BrainFog #DailySlog #LongCOVID #COVIDSky #LC #MECFS #PEM
["But you still managed to make this, didn't you?" Yes. Yes, I did. And it only took me six days]
Reposted by COVID Chronicles
This.
This is the problem.
OH and S standards are different for HCWs and for the life of me (and them) I can't understand why.
This is the problem.
OH and S standards are different for HCWs and for the life of me (and them) I can't understand why.
December 19, 2025 at 1:27 AM
This.
This is the problem.
OH and S standards are different for HCWs and for the life of me (and them) I can't understand why.
This is the problem.
OH and S standards are different for HCWs and for the life of me (and them) I can't understand why.
Day 1195—Dr John Goldman, infectious disease specialist at UPMC, tells ABC News that COVID's just the flu
Why? Because if you're healthy, it no longer kills you
Dear John: COVID doesn't have to kill you to end your life. Signed, millions of young, formerly healthy people crippled by #LongCOVID
Why? Because if you're healthy, it no longer kills you
Dear John: COVID doesn't have to kill you to end your life. Signed, millions of young, formerly healthy people crippled by #LongCOVID
December 17, 2025 at 8:50 PM
Day 1195—Dr John Goldman, infectious disease specialist at UPMC, tells ABC News that COVID's just the flu
Why? Because if you're healthy, it no longer kills you
Dear John: COVID doesn't have to kill you to end your life. Signed, millions of young, formerly healthy people crippled by #LongCOVID
Why? Because if you're healthy, it no longer kills you
Dear John: COVID doesn't have to kill you to end your life. Signed, millions of young, formerly healthy people crippled by #LongCOVID
Reposted by COVID Chronicles
A lot of people are sick right now.
Flu and Covid are raging, but the good news is a well fitted respirator can prevent both!
A good mask like an N95 is very effective at stopping flu and Covid.
My article looks at how to choose one, how to fit test, where to buy & more.
Mask up & save lives!
Flu and Covid are raging, but the good news is a well fitted respirator can prevent both!
A good mask like an N95 is very effective at stopping flu and Covid.
My article looks at how to choose one, how to fit test, where to buy & more.
Mask up & save lives!
We’re Witnessing the Fall of Public Health… and Your Best Tool is a Mask
Measles in Texas, bird flu in Louisiana, tuberculosis in Kansas and Covid everywhere. Public health has been dying a slow death for years, we can’t count on it anymore. What can we count on? A mask!
www.disabledginger.com
December 17, 2025 at 5:39 AM
A lot of people are sick right now.
Flu and Covid are raging, but the good news is a well fitted respirator can prevent both!
A good mask like an N95 is very effective at stopping flu and Covid.
My article looks at how to choose one, how to fit test, where to buy & more.
Mask up & save lives!
Flu and Covid are raging, but the good news is a well fitted respirator can prevent both!
A good mask like an N95 is very effective at stopping flu and Covid.
My article looks at how to choose one, how to fit test, where to buy & more.
Mask up & save lives!
Reposted by COVID Chronicles
How long will it be before we are as appalled at the idea that we ever went without an N95 in places where smoking used to be allowed?
Or an unmasked healthcare worker is as unthinkable as one smoking while examining a bleeding wound without gloves, or even washing their hands?
Or an unmasked healthcare worker is as unthinkable as one smoking while examining a bleeding wound without gloves, or even washing their hands?
December 15, 2025 at 11:48 PM
How long will it be before we are as appalled at the idea that we ever went without an N95 in places where smoking used to be allowed?
Or an unmasked healthcare worker is as unthinkable as one smoking while examining a bleeding wound without gloves, or even washing their hands?
Or an unmasked healthcare worker is as unthinkable as one smoking while examining a bleeding wound without gloves, or even washing their hands?
"The biggest problem may be resisting pressures to be more active, from health professionals, family, peers and the need to maintain self-esteem."
The last part of that sentence gave me pause. This is a valuable read. #LongCOVID #MECFS
The last part of that sentence gave me pause. This is a valuable read. #LongCOVID #MECFS
1) New factsheet: ME/CFS - information for medical professionals (6 pages).
Written by Prof. Emeritus Jonathon Edwards and members of the Science for ME forum. A valuable text, useful to bookmark. A couple of quotes from key paragraphs 👇
Written by Prof. Emeritus Jonathon Edwards and members of the Science for ME forum. A valuable text, useful to bookmark. A couple of quotes from key paragraphs 👇
December 15, 2025 at 11:45 PM
"The biggest problem may be resisting pressures to be more active, from health professionals, family, peers and the need to maintain self-esteem."
The last part of that sentence gave me pause. This is a valuable read. #LongCOVID #MECFS
The last part of that sentence gave me pause. This is a valuable read. #LongCOVID #MECFS
Something else to look forward to
Thanks a lot, SARS CoV-2
→Depression isn't the only thing that leads to "loss of self-confidence & difficulty concentrating"—Post-viral cognitive impairment & a complete loss of function will do that too. Just be glad it hasn't happened to you—yet #LongCOVID #MECFS
Thanks a lot, SARS CoV-2
→Depression isn't the only thing that leads to "loss of self-confidence & difficulty concentrating"—Post-viral cognitive impairment & a complete loss of function will do that too. Just be glad it hasn't happened to you—yet #LongCOVID #MECFS
Six specific depressive symptoms in midlife, including loss of self-confidence and difficulty concentrating, are linked to a higher risk of developing dementia more than 20 years later.
Specific depressive symptoms in midlife linked to increased dementia risk
Six particular depressive symptoms when experienced in midlife predict dementia risk more than two decades later, finds a new study led by University College London (UCL) researchers.
medicalxpress.com
December 15, 2025 at 11:42 PM
Something else to look forward to
Thanks a lot, SARS CoV-2
→Depression isn't the only thing that leads to "loss of self-confidence & difficulty concentrating"—Post-viral cognitive impairment & a complete loss of function will do that too. Just be glad it hasn't happened to you—yet #LongCOVID #MECFS
Thanks a lot, SARS CoV-2
→Depression isn't the only thing that leads to "loss of self-confidence & difficulty concentrating"—Post-viral cognitive impairment & a complete loss of function will do that too. Just be glad it hasn't happened to you—yet #LongCOVID #MECFS
"Since Nov. 13, Porzingis has missed 10 of 14 games. The Hawks said in order to ensure Porzingis continues to make progress toward a full recovery, the center will continue this current period of limited basketball activities."
Yeah, good luck with that. #LongCOVID
Yeah, good luck with that. #LongCOVID
Hawks' Porzingis sidelined 2 weeks with illness
Hawks center Kristaps Porzingis will miss the next two weeks and undergo further evaluations while dealing with a recent illness.
www.espn.com
December 15, 2025 at 3:33 AM
"Since Nov. 13, Porzingis has missed 10 of 14 games. The Hawks said in order to ensure Porzingis continues to make progress toward a full recovery, the center will continue this current period of limited basketball activities."
Yeah, good luck with that. #LongCOVID
Yeah, good luck with that. #LongCOVID
Alterations in gut microbiota and associated metabolites in patients with chronic fatigue syndrome.
Found a positive correlation of Alistipes & Rikenellaceae with multiple SCFAs & symptomatic improvement & a negative correlation between isovalerate and fatigue severity.
doi.org/10.1038/s415...
Found a positive correlation of Alistipes & Rikenellaceae with multiple SCFAs & symptomatic improvement & a negative correlation between isovalerate and fatigue severity.
doi.org/10.1038/s415...
December 13, 2025 at 8:30 PM
Alterations in gut microbiota and associated metabolites in patients with chronic fatigue syndrome.
Found a positive correlation of Alistipes & Rikenellaceae with multiple SCFAs & symptomatic improvement & a negative correlation between isovalerate and fatigue severity.
doi.org/10.1038/s415...
Found a positive correlation of Alistipes & Rikenellaceae with multiple SCFAs & symptomatic improvement & a negative correlation between isovalerate and fatigue severity.
doi.org/10.1038/s415...
Finally, some actionable intel:
"Because the IL-6 and JAK-STAT pathways were among the top upregulated pathways in both cohorts, we have initiated a clinical trial to evaluate the therapeutic efficacy of the JAK1 inhibitor abrocitinib for Long COVID"
Now you're talking.
"Because the IL-6 and JAK-STAT pathways were among the top upregulated pathways in both cohorts, we have initiated a clinical trial to evaluate the therapeutic efficacy of the JAK1 inhibitor abrocitinib for Long COVID"
Now you're talking.
December 12, 2025 at 6:51 PM
Finally, some actionable intel:
"Because the IL-6 and JAK-STAT pathways were among the top upregulated pathways in both cohorts, we have initiated a clinical trial to evaluate the therapeutic efficacy of the JAK1 inhibitor abrocitinib for Long COVID"
Now you're talking.
"Because the IL-6 and JAK-STAT pathways were among the top upregulated pathways in both cohorts, we have initiated a clinical trial to evaluate the therapeutic efficacy of the JAK1 inhibitor abrocitinib for Long COVID"
Now you're talking.
Reposted by COVID Chronicles
“One fundamental challenge for managing conditions like long COVID is to identify the mechanisms operating in each individual affected” www.nature.com/articles/d41...
Long-COVID research just got a big funding boost: will it find new treatments?
The German government has committed half a billion euros to research into long COVID and other post-infection syndromes.
www.nature.com
December 11, 2025 at 4:52 PM
“One fundamental challenge for managing conditions like long COVID is to identify the mechanisms operating in each individual affected” www.nature.com/articles/d41...
Reposted by COVID Chronicles
Long COVID in children is real, common, and still widely misunderstood. New pediatric studies show that kids and teens can experience lasting effects after infection, and reinfections significantly increase the risks.
December 11, 2025 at 3:19 PM
Long COVID in children is real, common, and still widely misunderstood. New pediatric studies show that kids and teens can experience lasting effects after infection, and reinfections significantly increase the risks.
Reposted by COVID Chronicles
“We sought out Amy & PolyBio because we cannot afford less than the best knowledge & information to help guide our [mAb trials],” said Invivyd chairman Marc Elia. PolyBio has funded 4+ clinical trials & most recently is supporting sample analysis for a RCT of Anktiva in Long Covid.
December 10, 2025 at 6:37 PM
“We sought out Amy & PolyBio because we cannot afford less than the best knowledge & information to help guide our [mAb trials],” said Invivyd chairman Marc Elia. PolyBio has funded 4+ clinical trials & most recently is supporting sample analysis for a RCT of Anktiva in Long Covid.
For those of us who were wondering whether catching SARS CoV-2 still puts you at risk for developing debilitating post-acute sequelae...
(And I was wondering, not for my sake—I've been disabled with Long COVID since 2022—but in regards to my teenage son).
Pro tip for 2026:
Don't catch COVID.
(And I was wondering, not for my sake—I've been disabled with Long COVID since 2022—but in regards to my teenage son).
Pro tip for 2026:
Don't catch COVID.
A new RECOVER study of 6.4M health records shows Long COVID risk has not decreased from 2020–2024. Incidence stayed stable across variants, reinforcing Long COVID as an ongoing public health priority.
Read the study: doi.org/10.1093/cid/...
Read the study: doi.org/10.1093/cid/...
December 11, 2025 at 12:58 AM
For those of us who were wondering whether catching SARS CoV-2 still puts you at risk for developing debilitating post-acute sequelae...
(And I was wondering, not for my sake—I've been disabled with Long COVID since 2022—but in regards to my teenage son).
Pro tip for 2026:
Don't catch COVID.
(And I was wondering, not for my sake—I've been disabled with Long COVID since 2022—but in regards to my teenage son).
Pro tip for 2026:
Don't catch COVID.
Reposted by COVID Chronicles
"Ungoverning is not a neutral act. It is an ethical choice. It shifts power from the many to the few. It transforms rights into commodities. It turns need into opportunity for private profit. And it abandons the belief that a society should be judged by how it treats the vulnerable."
Danielle Smith is "Ungoverning" Alberta
And trying to break the very idea of Canada
markhamhislop.substack.com
December 7, 2025 at 12:40 AM
"Ungoverning is not a neutral act. It is an ethical choice. It shifts power from the many to the few. It transforms rights into commodities. It turns need into opportunity for private profit. And it abandons the belief that a society should be judged by how it treats the vulnerable."
The reason it's so hard to remain safe from Long COVID is that no indoor public space is sufficiently ventilated, no one realizes "just sniffles" is still destroying lives. We need a cultural shift regarding respiratory infections. We need for Public Health to do its job. #CanPoli #CleanAir
December 7, 2025 at 3:32 PM
Reposted by COVID Chronicles
Exactly this. Only I didn't put it so gently.
December 6, 2025 at 8:42 PM
Exactly this. Only I didn't put it so gently.
The flip-side: My son (m16) just left for a friend's (f17) house party & will be the only N95 there
No ventilation or testing
Because nobody sees the risk
He'll have to step out early
Will say it's to keep me safe
How is that fair?
This wouldn't be so hard if public health did it's FUCKING JOB
No ventilation or testing
Because nobody sees the risk
He'll have to step out early
Will say it's to keep me safe
How is that fair?
This wouldn't be so hard if public health did it's FUCKING JOB
If you live with someone who has long Covid or a post-viral illness & you’re doing a weekly circuit of maskless bars, restaurants & concerts, you're not "living your life." You're sacrificing theirs
December 6, 2025 at 12:05 AM
The flip-side: My son (m16) just left for a friend's (f17) house party & will be the only N95 there
No ventilation or testing
Because nobody sees the risk
He'll have to step out early
Will say it's to keep me safe
How is that fair?
This wouldn't be so hard if public health did it's FUCKING JOB
No ventilation or testing
Because nobody sees the risk
He'll have to step out early
Will say it's to keep me safe
How is that fair?
This wouldn't be so hard if public health did it's FUCKING JOB
Reposted by COVID Chronicles
A school study shows shared classroom time and poor air quality drive virus transmission more than close contact.
Prolonged exposure in poorly ventilated spaces is the main risk factor, suggesting ventilation improvements are key.
#SARSCoV2 #COVID #flu
#LongCOVID
nature.com/articles/s41...
Prolonged exposure in poorly ventilated spaces is the main risk factor, suggesting ventilation improvements are key.
#SARSCoV2 #COVID #flu
#LongCOVID
nature.com/articles/s41...
The relative contribution of close-proximity contacts, shared classroom exposure and indoor air quality to respiratory virus transmission in schools - Nature Communications
The relative importance of close-proximity interactions, shared space and air quality to the transmission of respiratory viruses is not well understood. Here, the authors investigate this question by ...
nature.com
December 5, 2025 at 4:50 PM
A school study shows shared classroom time and poor air quality drive virus transmission more than close contact.
Prolonged exposure in poorly ventilated spaces is the main risk factor, suggesting ventilation improvements are key.
#SARSCoV2 #COVID #flu
#LongCOVID
nature.com/articles/s41...
Prolonged exposure in poorly ventilated spaces is the main risk factor, suggesting ventilation improvements are key.
#SARSCoV2 #COVID #flu
#LongCOVID
nature.com/articles/s41...
Reposted by COVID Chronicles
Day 5 #ArtAdventCalendar • This is my first #MECFS #symptomatology #embroidery: paresthesia (hand 1) 2016. The idea came to me while doing a meditation technique to dissect the tingling sensations in my body to make them less overwhelming. #SciArt
December 5, 2025 at 4:04 PM
Day 5 #ArtAdventCalendar • This is my first #MECFS #symptomatology #embroidery: paresthesia (hand 1) 2016. The idea came to me while doing a meditation technique to dissect the tingling sensations in my body to make them less overwhelming. #SciArt
Reposted by COVID Chronicles
New research shows major damage in the brain stress system of people with very severe ME/CFS.
The key finding: a near-loss of the neurons that start the cortisol stress response. This helps explain low cortisol and many symptoms.
Let’s break it down in simple language.
The key finding: a near-loss of the neurons that start the cortisol stress response. This helps explain low cortisol and many symptoms.
Let’s break it down in simple language.
December 5, 2025 at 6:00 PM
New research shows major damage in the brain stress system of people with very severe ME/CFS.
The key finding: a near-loss of the neurons that start the cortisol stress response. This helps explain low cortisol and many symptoms.
Let’s break it down in simple language.
The key finding: a near-loss of the neurons that start the cortisol stress response. This helps explain low cortisol and many symptoms.
Let’s break it down in simple language.
Reposted by COVID Chronicles
National University Hospital Singapore studied 189 people and found stroke patients with prior COVID-19 had 73% worse recovery at 3 months.
Their blood showed lingering immune and protein-synthesis disruptions that may impair brain healing.
www.sciencedirect.com/science/arti...
Their blood showed lingering immune and protein-synthesis disruptions that may impair brain healing.
www.sciencedirect.com/science/arti...
Persistent renin-angiotensin system and inflammatory dysregulation following COVID-19 impairs ischemic stroke recovery
Previous studies indicate that stroke recovery is worse in patients with prior COVID-19, suggesting persistent biological perturbations. We investigat…
www.sciencedirect.com
December 4, 2025 at 11:15 PM
National University Hospital Singapore studied 189 people and found stroke patients with prior COVID-19 had 73% worse recovery at 3 months.
Their blood showed lingering immune and protein-synthesis disruptions that may impair brain healing.
www.sciencedirect.com/science/arti...
Their blood showed lingering immune and protein-synthesis disruptions that may impair brain healing.
www.sciencedirect.com/science/arti...
Reposted by COVID Chronicles
Yale scientists reviewed 100 years of records and found that Long COVID is part of a larger pattern.
Viruses like polio, SARS, and EBV have long caused lasting illness in some people, often through immune dysfunction
www.cell.com/trends/immun...
Viruses like polio, SARS, and EBV have long caused lasting illness in some people, often through immune dysfunction
www.cell.com/trends/immun...
The lingering shadow of epidemics: post-acute sequelae across history
The SARS-CoV-2 pandemic has drawn global attention to post-acute infection syndromes
(PAIS), with millions affected by post-acute sequelae of COVID-19 (PASC, or Long COVID).
While Long COVID is newly ...
www.cell.com
December 4, 2025 at 4:07 PM
Yale scientists reviewed 100 years of records and found that Long COVID is part of a larger pattern.
Viruses like polio, SARS, and EBV have long caused lasting illness in some people, often through immune dysfunction
www.cell.com/trends/immun...
Viruses like polio, SARS, and EBV have long caused lasting illness in some people, often through immune dysfunction
www.cell.com/trends/immun...
If vaccine-injured Long COVID turns out to be a thing—and it could very well be—it'll be due to some people's inability to clear the SARS CoV-2 proteins that vaccines use to prompt our immunity.
SARS CoV-2 proteins.
COVID was going to maim us regardless. Why? Wish we knew. But until we do…
SARS CoV-2 proteins.
COVID was going to maim us regardless. Why? Wish we knew. But until we do…
"I'm convinced the spike protein is dangerous! No way I'm letting that anywhere near my body, whether it's by vax or infection! In addition to refusing the vax, I'm going to do all I can to prevent infection!" is a logically consistent position that virtually no one appears to take. 1/
a close up of a man 's face with the word fascinating written below him
Alt: Spock: Fascinating.
media.tenor.com
December 3, 2025 at 5:49 PM
If vaccine-injured Long COVID turns out to be a thing—and it could very well be—it'll be due to some people's inability to clear the SARS CoV-2 proteins that vaccines use to prompt our immunity.
SARS CoV-2 proteins.
COVID was going to maim us regardless. Why? Wish we knew. But until we do…
SARS CoV-2 proteins.
COVID was going to maim us regardless. Why? Wish we knew. But until we do…
To those who say:
"I'm still on X because they are on X"
A quick reminder:
People are still on X because you are on X.
#BeTheChange you want to see in the world. The change we desperately need. Please pass it along to your twitter feed.
"I'm still on X because they are on X"
A quick reminder:
People are still on X because you are on X.
#BeTheChange you want to see in the world. The change we desperately need. Please pass it along to your twitter feed.
Why are Amy Proal @polybiorf.bsky.social David Putrino @putrinolab.bsky.social & so many others more active on X than here?
Why are we still legitimizing malignant platforms? Knowing what we know about the societal damage they're causing (see: how MAGA won; misinformation, apathy). Esp given that:
Why are we still legitimizing malignant platforms? Knowing what we know about the societal damage they're causing (see: how MAGA won; misinformation, apathy). Esp given that:
Scientists Leaving Elon Musk’s X are Driving Growth on Bluesky: Study
With rising engagement and originality, Bluesky is fast becoming a go-to platform for science communication and scholarly exchange.
observer.com
December 3, 2025 at 4:04 PM
To those who say:
"I'm still on X because they are on X"
A quick reminder:
People are still on X because you are on X.
#BeTheChange you want to see in the world. The change we desperately need. Please pass it along to your twitter feed.
"I'm still on X because they are on X"
A quick reminder:
People are still on X because you are on X.
#BeTheChange you want to see in the world. The change we desperately need. Please pass it along to your twitter feed.
I thought we were friends
“Sorry”
What helped you clear your flare?
“X, Y, and a little bit of Z”
[Proceeds to try all three: zero benefit]
#FuckME #LongCOVID #MECFS
“Sorry”
What helped you clear your flare?
“X, Y, and a little bit of Z”
[Proceeds to try all three: zero benefit]
#FuckME #LongCOVID #MECFS
December 3, 2025 at 3:48 PM
I thought we were friends
“Sorry”
What helped you clear your flare?
“X, Y, and a little bit of Z”
[Proceeds to try all three: zero benefit]
#FuckME #LongCOVID #MECFS
“Sorry”
What helped you clear your flare?
“X, Y, and a little bit of Z”
[Proceeds to try all three: zero benefit]
#FuckME #LongCOVID #MECFS