Cheri Sirois
@cherisirois.bsky.social
Scientist of mostly invisible things. Editor at Cell (speaking only for myself here). 🗣️EN/ES 😷🦠🔬🧪🧬🌈✨ #immunosky #ProtectTransKids #ProtectTransAdults
The ~velocity~ with which I found the link for the quiz to learn what antibiotic I am…! (moxifloxacin 🤩)
It’s World AMR Awareness Week, and this year I had the honor to re-imagine and doodle the antibiotics in the antibiotic personality quiz 😇🖍️
Thank u @brxad.bsky.social for this amazing and fun opportunity!
C’mon, take the quiz, it’s a #WAAW tradition 😉💊
#IDSky
quiz.tryinteract.com#/59e68e3a8ec...
Thank u @brxad.bsky.social for this amazing and fun opportunity!
C’mon, take the quiz, it’s a #WAAW tradition 😉💊
#IDSky
quiz.tryinteract.com#/59e68e3a8ec...
November 19, 2025 at 3:12 AM
The ~velocity~ with which I found the link for the quiz to learn what antibiotic I am…! (moxifloxacin 🤩)
Reposted by Cheri Sirois
A study by Dorothy P. Schafer, PhD, and Travis E. Faust, PhD, in Cell explains how cell types in the brain communicate in response to changes in sensory input to remodel synapses: direc.to/nJHH
Alzheimer’s and ALS patients have synaptic damage.
@travisfaust.bsky.social @cp-cell.bsky.social
Alzheimer’s and ALS patients have synaptic damage.
@travisfaust.bsky.social @cp-cell.bsky.social
UMass Chan scientists show how the non-neuronal brain cells communicate to coordinate rewiring of brain
A study by Dorothy P. Schafer, PhD, and Travis E. Faust, PhD, explains how two different cell types in the brain communicate in response to changes in sensory input.
direc.to
October 7, 2025 at 12:17 PM
A study by Dorothy P. Schafer, PhD, and Travis E. Faust, PhD, in Cell explains how cell types in the brain communicate in response to changes in sensory input to remodel synapses: direc.to/nJHH
Alzheimer’s and ALS patients have synaptic damage.
@travisfaust.bsky.social @cp-cell.bsky.social
Alzheimer’s and ALS patients have synaptic damage.
@travisfaust.bsky.social @cp-cell.bsky.social
Reposted by Cheri Sirois
Check out our new RAEFISH spatial transcriptomics technology published in Cell! This work represents the first time that transcripts from more than 20,000 genes were directly imaged in situ with any technology, and the first time numerous gRNAs were directly probed in an image-based CRISPR screen.
Now online! Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution
Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution
RAEFISH delivers whole-transcriptome (>20,000 genes) imaging at single-molecule resolution in cells and tissues and enables direct gRNA detection for high-content, image-based CRISPR screens.
dlvr.it
October 8, 2025 at 7:24 AM
Check out our new RAEFISH spatial transcriptomics technology published in Cell! This work represents the first time that transcripts from more than 20,000 genes were directly imaged in situ with any technology, and the first time numerous gRNAs were directly probed in an image-based CRISPR screen.
Reposted by Cheri Sirois
The editorial team at #Cell wishes heartfelt congratulations to the winners of the 2025 #NobelPrize in Physiology or Medicine, Drs. Mary Brunkow, Fred Ramsdell, & Shimon Sakaguchi!
View their related research published in Cell Press journals: spkl.io/6013AVK2P
@cherisirois.bsky.social
View their related research published in Cell Press journals: spkl.io/6013AVK2P
@cherisirois.bsky.social
October 6, 2025 at 6:49 PM
The editorial team at #Cell wishes heartfelt congratulations to the winners of the 2025 #NobelPrize in Physiology or Medicine, Drs. Mary Brunkow, Fred Ramsdell, & Shimon Sakaguchi!
View their related research published in Cell Press journals: spkl.io/6013AVK2P
@cherisirois.bsky.social
View their related research published in Cell Press journals: spkl.io/6013AVK2P
@cherisirois.bsky.social
If you are near Boston and you would like to get updated flu and COVID vaccines with no hassle, no required ID or insurance, check out these upcoming clinics. Vaccines are available to EVERYONE (except newborns) and they have some other vaccines available, too.
www.boston.gov/government/c...
www.boston.gov/government/c...
Free Vaccine Clinics in Boston
Everyone ages six months and older is encouraged to get the updated flu and COVID-19 vaccines. Pregnant parents, babies, and older adults should consult their health care professional about RSV vaccin...
www.boston.gov
September 25, 2025 at 12:27 PM
If you are near Boston and you would like to get updated flu and COVID vaccines with no hassle, no required ID or insurance, check out these upcoming clinics. Vaccines are available to EVERYONE (except newborns) and they have some other vaccines available, too.
www.boston.gov/government/c...
www.boston.gov/government/c...
Reposted by Cheri Sirois
To get clean air infrastructure everywhere, we need as many governments, states, cities, nonprofits, schools, businesses etc. to sign on as possible. Please read the pledge, share it, and push your local orgs to join!
Link to Global Pledge for Healthy Indoor Air: aas.eventsair.com/healthy-indo...
Link to Global Pledge for Healthy Indoor Air: aas.eventsair.com/healthy-indo...
Pledge
aas.eventsair.com
September 24, 2025 at 10:54 PM
To get clean air infrastructure everywhere, we need as many governments, states, cities, nonprofits, schools, businesses etc. to sign on as possible. Please read the pledge, share it, and push your local orgs to join!
Link to Global Pledge for Healthy Indoor Air: aas.eventsair.com/healthy-indo...
Link to Global Pledge for Healthy Indoor Air: aas.eventsair.com/healthy-indo...
Reposted by Cheri Sirois
Yesterday, history happened at the UN: For the first time hundreds of orgs signed a global pledge declaring that healthy indoor air is a human right.
Healthy indoor air is a key tool for preventing pandemics, building climate resilience, and increasing health equity. We need it everywhere!
Healthy indoor air is a key tool for preventing pandemics, building climate resilience, and increasing health equity. We need it everywhere!
September 24, 2025 at 10:53 PM
Yesterday, history happened at the UN: For the first time hundreds of orgs signed a global pledge declaring that healthy indoor air is a human right.
Healthy indoor air is a key tool for preventing pandemics, building climate resilience, and increasing health equity. We need it everywhere!
Healthy indoor air is a key tool for preventing pandemics, building climate resilience, and increasing health equity. We need it everywhere!
Reposted by Cheri Sirois
Over 200 leaders — including 10 Nobel laureates & top AI experts — call for AI red lines to prevent dangerous uses. I’ve signed the Global Call for AI Red Lines for responsible use of AI: red-lines.ai
200+ prominent figures endorse Global Call for AI Red Lines
AI could soon far surpass human capabilities and escalate risks such as engineered pandemics, widespread disinformation, large-scale manipulation of individuals including children...
red-lines.ai
September 23, 2025 at 3:12 PM
Over 200 leaders — including 10 Nobel laureates & top AI experts — call for AI red lines to prevent dangerous uses. I’ve signed the Global Call for AI Red Lines for responsible use of AI: red-lines.ai
Reposted by Cheri Sirois
This is an active research area, but avoiding illness/fever in pregnancy is wise—and so is listening to experts who’ve dedicated their lives to helping
www.acog.org/news/news-re...
pubmed.ncbi.nlm.nih.gov/22562209/
jamanetwork.com/journals/jam...
bmcmedicine.biomedcentral.com/articles/10....
www.acog.org/news/news-re...
pubmed.ncbi.nlm.nih.gov/22562209/
jamanetwork.com/journals/jam...
bmcmedicine.biomedcentral.com/articles/10....
ACOG Affirms Safety Benefits Acetaminophen Pregnancy
"The data from numerous studies have shown that acetaminophen plays an important—and safe—role in the well-being of pregnant women."
www.acog.org
September 23, 2025 at 3:19 PM
This is an active research area, but avoiding illness/fever in pregnancy is wise—and so is listening to experts who’ve dedicated their lives to helping
www.acog.org/news/news-re...
pubmed.ncbi.nlm.nih.gov/22562209/
jamanetwork.com/journals/jam...
bmcmedicine.biomedcentral.com/articles/10....
www.acog.org/news/news-re...
pubmed.ncbi.nlm.nih.gov/22562209/
jamanetwork.com/journals/jam...
bmcmedicine.biomedcentral.com/articles/10....
Reposted by Cheri Sirois
To be clear, there are no data that provide a link between short-term use of Tylenol during pregnancy and autism. In fact, one of the best prospective studies w/ sibling controls, if anything, pointed to a protective effect for use less than 7 days
acamh.onlinelibrary.wiley.com/doi/10.1002/...
acamh.onlinelibrary.wiley.com/doi/10.1002/...
September 23, 2025 at 3:05 PM
To be clear, there are no data that provide a link between short-term use of Tylenol during pregnancy and autism. In fact, one of the best prospective studies w/ sibling controls, if anything, pointed to a protective effect for use less than 7 days
acamh.onlinelibrary.wiley.com/doi/10.1002/...
acamh.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Cheri Sirois
"Pay no attention: Global health agencies dismiss false Trump claim on everyday painkillers"
This cannot be shared enough times.
This cannot be shared enough times.
‘Pay no attention’: global health agencies dismiss false Trump claim on everyday painkillers
Medical experts and regulators say US president should not be questioning established science
www.theguardian.com
September 23, 2025 at 1:29 PM
"Pay no attention: Global health agencies dismiss false Trump claim on everyday painkillers"
This cannot be shared enough times.
This cannot be shared enough times.
Reposted by Cheri Sirois
How many chromosomes can an animal have?
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
Constraints on chromosome evolution revealed by the 229 chromosome pairs of the Atlas blue butterfly
The genome of the Atlas blue butterfly contains ten times more chromosomes than most
butterflies, and more than any other known diploid animal. Wright et al. show that
this extraordinary karyotype is ...
tinyurl.com
September 11, 2025 at 3:22 PM
How many chromosomes can an animal have?
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
“The loss to state economies would be about 40% greater than the federal savings, as losses ripple through state and local economies. In other words, for every $1 the federal government saves, state and local economies would lose $1.40.”
mediarelations.gwu.edu/new-research...
mediarelations.gwu.edu/new-research...
New Research: Proposed CDC Budget Cuts Harm Public Health | Media Relations | The George Washington University
A new report by George Washington University researchers finds that proposed Fiscal Year 2026 budget cuts to the Centers for Disease Control and Prevention, if enacted, would endanger public health an...
mediarelations.gwu.edu
September 12, 2025 at 11:18 AM
“The loss to state economies would be about 40% greater than the federal savings, as losses ripple through state and local economies. In other words, for every $1 the federal government saves, state and local economies would lose $1.40.”
mediarelations.gwu.edu/new-research...
mediarelations.gwu.edu/new-research...
Reposted by Cheri Sirois
Reposted by Cheri Sirois
Applying to the NSF-GRFP (or another fellowship) on a tight deadline?
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
September 9, 2025 at 4:14 PM
Applying to the NSF-GRFP (or another fellowship) on a tight deadline?
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
Reposted by Cheri Sirois
The Empire State can’t afford to fall behind. A group of scientists is launching NY-CURES to fight for state and city level investment in research.✊
📢 Sign up & show Albany we stand UNITED for science.
👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social
#AdvocateForScience #NYCURES
📢 Sign up & show Albany we stand UNITED for science.
👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social
#AdvocateForScience #NYCURES
September 9, 2025 at 3:33 PM
The Empire State can’t afford to fall behind. A group of scientists is launching NY-CURES to fight for state and city level investment in research.✊
📢 Sign up & show Albany we stand UNITED for science.
👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social
#AdvocateForScience #NYCURES
📢 Sign up & show Albany we stand UNITED for science.
👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social
#AdvocateForScience #NYCURES
Science has saved countless lives - and will save many more if we let it. To fight cuts to research funding in the U.S. we need to share our stories! #ScienceSavedMe (tinyurl.com/m65339fh)
ScienceSavedMe Testimonials - YouTube
tinyurl.com
September 9, 2025 at 11:49 AM
Science has saved countless lives - and will save many more if we let it. To fight cuts to research funding in the U.S. we need to share our stories! #ScienceSavedMe (tinyurl.com/m65339fh)
Reposted by Cheri Sirois
Science has already saved countless lives and will save many more if we let it. Hearing firsthand from patients whose lives have been saved by medical research (tinyurl.com/m65339fh) shows how vital this funding is, even for those lucky enough not to have needed it yet.
Please share
#ScienceSavedMe
Please share
#ScienceSavedMe
September 3, 2025 at 10:12 PM
Science has already saved countless lives and will save many more if we let it. Hearing firsthand from patients whose lives have been saved by medical research (tinyurl.com/m65339fh) shows how vital this funding is, even for those lucky enough not to have needed it yet.
Please share
#ScienceSavedMe
Please share
#ScienceSavedMe
We need new models for funding science in the U.S. Let’s goooo! 🚀
🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀
Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities.
Sign up. Stay informed. Join the movement: www.nycures.org/
Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities.
Sign up. Stay informed. Join the movement: www.nycures.org/
September 9, 2025 at 11:31 AM
We need new models for funding science in the U.S. Let’s goooo! 🚀
Reposted by Cheri Sirois
Getting ready for #CSNeuroimmune25 tomorrow in NYC! Excited to see everyone, and looking forward to some cool #neuroimmunology! @cp-neuron.bsky.social @cp-immunity.bsky.social www.cell-symposia.com/neuroimmunol...
September 6, 2025 at 11:40 PM
Getting ready for #CSNeuroimmune25 tomorrow in NYC! Excited to see everyone, and looking forward to some cool #neuroimmunology! @cp-neuron.bsky.social @cp-immunity.bsky.social www.cell-symposia.com/neuroimmunol...
Reposted by Cheri Sirois
The lack of mainstream coverage of regular huge protests reminds me of a talk from a Twitter employees who explained that they had to drop BLM off the Trending Tags section because otherwise it would have been there permanently. The modern media environment has no appetite for sustained movements.
The crowd has no beginning and no end as it begins its march to the White House
September 7, 2025 at 12:03 AM
The lack of mainstream coverage of regular huge protests reminds me of a talk from a Twitter employees who explained that they had to drop BLM off the Trending Tags section because otherwise it would have been there permanently. The modern media environment has no appetite for sustained movements.
Reposted by Cheri Sirois
For no real reason, thinking about this piece about the "headline news about famous guy saying transphobic thing" industrial complex I wrote for Paste two years ago. Just before everything got worse.
www.pastemagazine.com/music/transp...
www.pastemagazine.com/music/transp...
Always The Topic, Rarely The Voice
Paste Magazine is your source for the best music, movies, TV, comedy, videogames, books, comics, craft beer, politics and more. Discover your favorite albums and films.
www.pastemagazine.com
September 3, 2025 at 9:29 PM
For no real reason, thinking about this piece about the "headline news about famous guy saying transphobic thing" industrial complex I wrote for Paste two years ago. Just before everything got worse.
www.pastemagazine.com/music/transp...
www.pastemagazine.com/music/transp...
If you've been looking for a big, juicy, up-to-date review on interferons, incorporating the latest understanding about how IFN-lambda fits into the picture... well, here it is!👇 (Thanks to
@lozanzi.bsky.social and @danielboehmer.bsky.social
for writing it!)
@lozanzi.bsky.social and @danielboehmer.bsky.social
for writing it!)
Finally officially out in the latest issue of @cp-cell.bsky.social as a #free #featured #LeadingEdge paper: everything you wanted to know about #InterferonPower! ❤️ @danielboehmer.bsky.social @bostonchildrens.bsky.social @harvardmed.bsky.social www.cell.com/cell/fulltex...
Interferons in health and disease
The cytokine messenger proteins known as interferons are central to protective immune
responses against infections, but they are also involved in inflammatory and autoimmune
diseases. This review maps...
www.cell.com
September 3, 2025 at 5:16 PM
If you've been looking for a big, juicy, up-to-date review on interferons, incorporating the latest understanding about how IFN-lambda fits into the picture... well, here it is!👇 (Thanks to
@lozanzi.bsky.social and @danielboehmer.bsky.social
for writing it!)
@lozanzi.bsky.social and @danielboehmer.bsky.social
for writing it!)
Reposted by Cheri Sirois
Now online! Extensive cross-species transmission of pathogens and antibiotic resistance genes in mammals neglected by public health surveillance
Extensive cross-species transmission of pathogens and antibiotic resistance genes in mammals neglected by public health surveillance
Microbiome and virome sequencing of non-traditional farmed and wild mammals reveal an uncharted diversity of potential pathogens and mobile antibiotic resistance genes, providing insights into the risks of zoonotic disease and antibiotic resistance at the human-animal interface.
dlvr.it
August 27, 2025 at 10:39 PM
Now online! Extensive cross-species transmission of pathogens and antibiotic resistance genes in mammals neglected by public health surveillance
Reposted by Cheri Sirois
Happy to share our work on the structure and function of the unusual E3 ligase ZNFX1 @cp-cell.bsky.social. It uses a nucleic acid-activated transthiolation mechanism, ubiquitinating and clustering RNA to protect cells in an immune response. @clausenlab.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles
Grabarczyk et al. show the structure and mechanism of a non-canonical ubiquitin ligase,
which is activated through nucleic-acid-induced oligomerization and is critical for
cell survival during immune ...
www.cell.com
August 27, 2025 at 7:04 PM
Happy to share our work on the structure and function of the unusual E3 ligase ZNFX1 @cp-cell.bsky.social. It uses a nucleic acid-activated transthiolation mechanism, ubiquitinating and clustering RNA to protect cells in an immune response. @clausenlab.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...