Marcus Böhme
@boehmemarcus.bsky.social
#Microbiota-#Gut-#Brain-Axis | from Early Life to #Aging | Neuroscientist & Nutrition | Working in R&D | Musician | PhD @uniklinik_jena | formerly @Pharmabiotic #cryanlab
📄 https://scholar.google.de/citations?user=SqMBfEQAAAAJ&hl=en
📄 https://scholar.google.de/citations?user=SqMBfEQAAAAJ&hl=en
Reposted by Marcus Böhme
Another review from my lab out this week, on analyzing gut microbiome data from global populations -- tackling computational challenges and providing practical frameworks and resources for the field
With Sabrina Arif, @richabdill.com, @samanthagraham.bsky.social
www.cell.com/trends/micro...
With Sabrina Arif, @richabdill.com, @samanthagraham.bsky.social
www.cell.com/trends/micro...
Analyzing human gut microbiome data from global populations: challenges and resources
Research on the human gut microbiome is expanding rapidly; yet, most published studies
focus on populations from high-income regions such as North America and Europe. Underrepresentation
of population...
www.cell.com
June 18, 2025 at 10:12 PM
Another review from my lab out this week, on analyzing gut microbiome data from global populations -- tackling computational challenges and providing practical frameworks and resources for the field
With Sabrina Arif, @richabdill.com, @samanthagraham.bsky.social
www.cell.com/trends/micro...
With Sabrina Arif, @richabdill.com, @samanthagraham.bsky.social
www.cell.com/trends/micro...
Reposted by Marcus Böhme
Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering
Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster
www.cell.com/cell-host-mi...
Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster
www.cell.com/cell-host-mi...
June 11, 2025 at 5:02 PM
Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering
Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster
www.cell.com/cell-host-mi...
Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster
www.cell.com/cell-host-mi...
Reposted by Marcus Böhme
📈With obesity and overweight expected to affect 50% of the global population by 2035, the need for change has never been clearer. Join experts on 5 June at #EUParliament for an in-depth discussion on tackling this growing health crisis. Register now: https://bit.ly/3EIlu1H
May 3, 2025 at 9:00 AM
📈With obesity and overweight expected to affect 50% of the global population by 2035, the need for change has never been clearer. Join experts on 5 June at #EUParliament for an in-depth discussion on tackling this growing health crisis. Register now: https://bit.ly/3EIlu1H
Reposted by Marcus Böhme
Excited to share our new work demonstrating a role for astrocytic inflammasome signaling in modulating hippocampal plasticity. @cp-immunity.bsky.social
All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...
All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...
Inflammasome signaling in astrocytes modulates hippocampal plasticity
The function of immune pathways in homeostatic neurobiology remains underexplored.
Zengeler et al. find that the inflammasome complex, typically associated with immune
responses, is involved in memory...
www.cell.com
May 3, 2025 at 1:45 AM
Excited to share our new work demonstrating a role for astrocytic inflammasome signaling in modulating hippocampal plasticity. @cp-immunity.bsky.social
All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...
All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...
Reposted by Marcus Böhme
Lots of recent papers discuss the nucleus of the solitary tract in interoception. In this review, we take a sensory processing perspective on how interoceptive signals are encoded in the NTS:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Interoceptive processing in the nucleus of the solitary tract
The interoceptive nervous system continuously monitors the status of visceral organs to synthesize internal perceptions and regulate behavioral and ph…
www.sciencedirect.com
April 16, 2025 at 4:02 AM
Lots of recent papers discuss the nucleus of the solitary tract in interoception. In this review, we take a sensory processing perspective on how interoceptive signals are encoded in the NTS:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Marcus Böhme
NEWS&VIEWS | LO Dragsted, @hroager.bsky.social , @catalinacuparencu.bsky.social (U Copenhagen):
A methodology for assessing dietary intake using stool metagenomes to detect food DNA🧬💩
https://bit.ly/4lfJ1aK ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab
A methodology for assessing dietary intake using stool metagenomes to detect food DNA🧬💩
https://bit.ly/4lfJ1aK ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab
Querying stool for dietary information - Nature Metabolism
Accurately determining food intake remains a substantial challenge in nutrition research. This issue of Nature Metabolism introduces a methodology for assessing dietary intake, using stool metagenomic data to detect food DNA from a broad range of foods.
bit.ly
April 9, 2025 at 6:23 PM
NEWS&VIEWS | LO Dragsted, @hroager.bsky.social , @catalinacuparencu.bsky.social (U Copenhagen):
A methodology for assessing dietary intake using stool metagenomes to detect food DNA🧬💩
https://bit.ly/4lfJ1aK ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab
A methodology for assessing dietary intake using stool metagenomes to detect food DNA🧬💩
https://bit.ly/4lfJ1aK ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab
Reposted by Marcus Böhme
A map of neural signals and circuits traces the logic of brain computation www.nature.com/articles/d41...
A map of neural signals and circuits traces the logic of brain computation
A large consortium of scientists adds functional data to neuronal wiring maps, seeking to crack the computational circuitry of the mouse brain.
www.nature.com
April 10, 2025 at 6:02 AM
A map of neural signals and circuits traces the logic of brain computation www.nature.com/articles/d41...
Reposted by Marcus Böhme
Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety: @cellpress.bsky.social www.cell.com/cell/fulltex...
April 7, 2025 at 2:42 PM
Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety: @cellpress.bsky.social www.cell.com/cell/fulltex...
Reposted by Marcus Böhme
In people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
April 7, 2025 at 3:06 PM
In people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
I am excited to share our latest publication where we investigated the impact of a #Bifidobacterium longum strain on #perinatal anxiety and depressive symptoms
#mood #stress #postpartum #gutbrainaxis
www.nature.com/articles/s41...
#mood #stress #postpartum #gutbrainaxis
www.nature.com/articles/s41...
The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial - Scientific Reports
Scientific Reports - The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial
www.nature.com
April 6, 2025 at 12:14 PM
I am excited to share our latest publication where we investigated the impact of a #Bifidobacterium longum strain on #perinatal anxiety and depressive symptoms
#mood #stress #postpartum #gutbrainaxis
www.nature.com/articles/s41...
#mood #stress #postpartum #gutbrainaxis
www.nature.com/articles/s41...
Reposted by Marcus Böhme
The gut microbiome's link with multiple sclerosis www.cell.com/cell-reports...
April 3, 2025 at 5:10 PM
The gut microbiome's link with multiple sclerosis www.cell.com/cell-reports...
Reposted by Marcus Böhme
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Bifidobacteria support optimal infant vaccine responses - Nature
Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probio...
www.nature.com
April 2, 2025 at 11:33 PM
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Marcus Böhme
Singapore study of 184 women found that daily probiotic Bifidobacterium longum NCC3001 during late pregnancy and postpartum did not ease anxiety or depression symptoms.
Results varied widely, suggesting more research is needed.
www.nature.com/articles/s41...
Results varied widely, suggesting more research is needed.
www.nature.com/articles/s41...
The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial - Scientific Reports
Scientific Reports - The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial
www.nature.com
April 2, 2025 at 11:52 AM
Singapore study of 184 women found that daily probiotic Bifidobacterium longum NCC3001 during late pregnancy and postpartum did not ease anxiety or depression symptoms.
Results varied widely, suggesting more research is needed.
www.nature.com/articles/s41...
Results varied widely, suggesting more research is needed.
www.nature.com/articles/s41...
Reposted by Marcus Böhme
Curious about the gut microbiome & its impacts on sleep throughout the adult lifespan? 🦠😴
You're in luck! @isbscience.org PhD student Jacob Cavon led a review of this topic for the @amiposts.bsky.social journal Letters in Applied Microbiology (just accepted): academic.oup.com/lambio/advan...
You're in luck! @isbscience.org PhD student Jacob Cavon led a review of this topic for the @amiposts.bsky.social journal Letters in Applied Microbiology (just accepted): academic.oup.com/lambio/advan...
The human gut microbiome and sleep across adulthood: associations and therapeutic potential
Abstract. Sleep is an essential homeostatic process that undergoes dynamic changes throughout the lifespan, with distinct life stages predisposed to specif
academic.oup.com
March 24, 2025 at 4:21 PM
Curious about the gut microbiome & its impacts on sleep throughout the adult lifespan? 🦠😴
You're in luck! @isbscience.org PhD student Jacob Cavon led a review of this topic for the @amiposts.bsky.social journal Letters in Applied Microbiology (just accepted): academic.oup.com/lambio/advan...
You're in luck! @isbscience.org PhD student Jacob Cavon led a review of this topic for the @amiposts.bsky.social journal Letters in Applied Microbiology (just accepted): academic.oup.com/lambio/advan...
Reposted by Marcus Böhme
I received a heartbreaking email today: A paper in a special issue I’m editing is being retracted because one of its authors is afraid of losing their job and their legal status in the U.S. if they publish a scientific study on evolution. Yes, on evolution, nature's engine of diversity.
March 29, 2025 at 11:52 PM
I received a heartbreaking email today: A paper in a special issue I’m editing is being retracted because one of its authors is afraid of losing their job and their legal status in the U.S. if they publish a scientific study on evolution. Yes, on evolution, nature's engine of diversity.
Reposted by Marcus Böhme
In this week’s @nature.com, we publish a group effort to outline a framework for studies with neural #organoids, #assembloids and transplantation. More details below 1/n
March 14, 2025 at 8:20 PM
In this week’s @nature.com, we publish a group effort to outline a framework for studies with neural #organoids, #assembloids and transplantation. More details below 1/n
Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 6, 2025 at 2:14 PM
Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Marcus Böhme
This administration is destroying US science.
"Foreign scientists hired under Title 42 have even more reason to worry... their visas require they leave the country within 60 days unless they obtain a new position. Many have put down roots, bought houses & have children in school."
"Foreign scientists hired under Title 42 have even more reason to worry... their visas require they leave the country within 60 days unless they obtain a new position. Many have put down roots, bought houses & have children in school."
February 27, 2025 at 12:54 PM
This administration is destroying US science.
"Foreign scientists hired under Title 42 have even more reason to worry... their visas require they leave the country within 60 days unless they obtain a new position. Many have put down roots, bought houses & have children in school."
"Foreign scientists hired under Title 42 have even more reason to worry... their visas require they leave the country within 60 days unless they obtain a new position. Many have put down roots, bought houses & have children in school."
Reposted by Marcus Böhme
What is your pace of aging? A new @nature.com feature on molecular clocks by gets into the issues surrounding these tests (can is really can't) nature.com/articles/d41... by @heidiledford.bsky.social
February 25, 2025 at 6:28 PM
What is your pace of aging? A new @nature.com feature on molecular clocks by gets into the issues surrounding these tests (can is really can't) nature.com/articles/d41... by @heidiledford.bsky.social
Reposted by Marcus Böhme
Great minds… within 24 hrs both us at @nature.com and @science.org make similar appeals to the research community. And @holdenthorp.bsky.social and I didn’t even exchange notes about it ;-)
🧪
www.nature.com/articles/d41...
www.science.org/doi/10.1126/...
🧪
www.nature.com/articles/d41...
www.science.org/doi/10.1126/...
Come together, right now
The chaos, conflicting information, firings, and hurtful rhetoric of the Trump administration’s approach to science over the past month are causing anxiety, grief, and concern for the scientific commu...
www.science.org
February 25, 2025 at 7:51 PM
Great minds… within 24 hrs both us at @nature.com and @science.org make similar appeals to the research community. And @holdenthorp.bsky.social and I didn’t even exchange notes about it ;-)
🧪
www.nature.com/articles/d41...
www.science.org/doi/10.1126/...
🧪
www.nature.com/articles/d41...
www.science.org/doi/10.1126/...
Reposted by Marcus Böhme
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.
https://go.nature.com/4gM6oW4
https://go.nature.com/4gM6oW4
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
go.nature.com
February 20, 2025 at 8:04 PM
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.
https://go.nature.com/4gM6oW4
https://go.nature.com/4gM6oW4
Reposted by Marcus Böhme
My brother is a wild-land forest fire fighter.
He wasn’t fired, but he says that the degraded workforce will struggle to function in the next fire season.
These are the heroes who risk everything to save lives and homes.
He wasn’t fired, but he says that the degraded workforce will struggle to function in the next fire season.
These are the heroes who risk everything to save lives and homes.
February 14, 2025 at 3:31 PM
My brother is a wild-land forest fire fighter.
He wasn’t fired, but he says that the degraded workforce will struggle to function in the next fire season.
These are the heroes who risk everything to save lives and homes.
He wasn’t fired, but he says that the degraded workforce will struggle to function in the next fire season.
These are the heroes who risk everything to save lives and homes.
Reposted by Marcus Böhme
Interested in doing a PhD in Austria focused on understanding how to engineer the composition of the gut microbiota?
Want to work with a brilliant computational biologist and microbiome researcher?
See below!
Want to work with a brilliant computational biologist and microbiome researcher?
See below!
Hi, we have an open PhD position in our lab starting winter 2025. Join the great MolMed PhD program at a vibrant research institution and help us understand probiotic engraftment. More info at www.dienerlab.com/posts/phd2025/ . Application through the MedUni portal: phd-recruiting.medunigraz.at
Open PhD position: Designing the niche space of the human gut microbiome
Deadline: March 21st, 2025 - apply here
Virtually every surface of our planet is colonized by microbes and the human body is no exception. The 38 trillion microbes living in our gut metabolize a large...
www.dienerlab.com
February 17, 2025 at 3:21 PM
Interested in doing a PhD in Austria focused on understanding how to engineer the composition of the gut microbiota?
Want to work with a brilliant computational biologist and microbiome researcher?
See below!
Want to work with a brilliant computational biologist and microbiome researcher?
See below!
Reposted by Marcus Böhme
A new way to measure your food intake, from your 💩
www.nature.com/articles/s42...
www.nature.com/articles/s42...
"proof-of-concept for detailed tracking of
individual-specific, health-relevant dietary patterns without the need for questionnaires."
www.nature.com/articles/s42...
www.nature.com/articles/s42...
"proof-of-concept for detailed tracking of
individual-specific, health-relevant dietary patterns without the need for questionnaires."
Querying stool for dietary information - Nature Metabolism
Accurately determining food intake remains a substantial challenge in nutrition research. This issue of Nature Metabolism introduces a methodology for assessing dietary intake, using stool metagenomic...
www.nature.com
February 18, 2025 at 2:06 PM
A new way to measure your food intake, from your 💩
www.nature.com/articles/s42...
www.nature.com/articles/s42...
"proof-of-concept for detailed tracking of
individual-specific, health-relevant dietary patterns without the need for questionnaires."
www.nature.com/articles/s42...
www.nature.com/articles/s42...
"proof-of-concept for detailed tracking of
individual-specific, health-relevant dietary patterns without the need for questionnaires."