Christian Diener
@cdiener.com
Lifelong relationship with microbes, now studying them for a living. Assistant Professor at MedUni Graz. Opinions are my own. He/him 🦠+💻=❤️
More socials at cdiener.com. Lab website at dienerlab.com.
More socials at cdiener.com. Lab website at dienerlab.com.
Reposted by Christian Diener
📣 Join us for the 2025 @isbscience.org Virtual Microbiome Symposium, focused on "Gut Microbial Metabolites and Their Impact on Host Systems".
co-director - @flash-point.bsky.social 🦠💥
It's free, & we have an amazing line-up of speakers!
Dec. 12th. Please share!
isbscience.org/2025-isb-vir...
co-director - @flash-point.bsky.social 🦠💥
It's free, & we have an amazing line-up of speakers!
Dec. 12th. Please share!
isbscience.org/2025-isb-vir...
2025 ISB Virtual Microbiome Symposium - Institute for Systems Biology (ISB)
Symposium Schedule All presentation times are shown in Pacific Daylight Time (GMT -07:00 / UTC -07:00) Time Talk / Session 9:00 Welcoming remarks by Sid Venkatesh Session One: Neural Effects
isbscience.org
November 13, 2025 at 7:13 AM
📣 Join us for the 2025 @isbscience.org Virtual Microbiome Symposium, focused on "Gut Microbial Metabolites and Their Impact on Host Systems".
co-director - @flash-point.bsky.social 🦠💥
It's free, & we have an amazing line-up of speakers!
Dec. 12th. Please share!
isbscience.org/2025-isb-vir...
co-director - @flash-point.bsky.social 🦠💥
It's free, & we have an amazing line-up of speakers!
Dec. 12th. Please share!
isbscience.org/2025-isb-vir...
Reposted by Christian Diener
Dr. Nick Quinn-Bohmann will present a Keynote Talk at this year's Future of the Microbiome Winter Summit (Nov. 18-20).
He'll talk about his work on using community-scale metabolic modeling to design personalized, microbiome-informed interventions. futureofmicrobiome.com/winter-summi...
He'll talk about his work on using community-scale metabolic modeling to design personalized, microbiome-informed interventions. futureofmicrobiome.com/winter-summi...
Winter Summit 2025 | The Future of Microbiome
Future of the Microbiome2025 Winter Summit Join us November 18-20, 2025! REGISTER NOW The Future of the Microbiome Winter Summit explores what’s next for the microbiome industry, bringing together bri...
futureofmicrobiome.com
November 11, 2025 at 9:55 PM
Dr. Nick Quinn-Bohmann will present a Keynote Talk at this year's Future of the Microbiome Winter Summit (Nov. 18-20).
He'll talk about his work on using community-scale metabolic modeling to design personalized, microbiome-informed interventions. futureofmicrobiome.com/winter-summi...
He'll talk about his work on using community-scale metabolic modeling to design personalized, microbiome-informed interventions. futureofmicrobiome.com/winter-summi...
Reposted by Christian Diener
Less than a week remains to apply to this exciting PhD position and join my team at Osnabrück University 👇
#microsky #mevosky @spp2389.bsky.social
A PhD position is available in my lab to work on:
Emergence and self-organisation of bacterial metabolism in consortia of cross-feeding bacteria.
Please RT
Deadline: 12.11.25
More infos 👇
shorturl.at/rAKAT
A PhD position is available in my lab to work on:
Emergence and self-organisation of bacterial metabolism in consortia of cross-feeding bacteria.
Please RT
Deadline: 12.11.25
More infos 👇
shorturl.at/rAKAT
November 5, 2025 at 7:45 AM
Less than a week remains to apply to this exciting PhD position and join my team at Osnabrück University 👇
Reposted by Christian Diener
🧬 🦠 🏙️
Urban vs rural lifestyles create dramatically different gut microbiomes. But how do these different gut microbiomes affect the host?
Excited to share our new paper: www.biorxiv.org/content/10.1...
Urban vs rural lifestyles create dramatically different gut microbiomes. But how do these different gut microbiomes affect the host?
Excited to share our new paper: www.biorxiv.org/content/10.1...
November 5, 2025 at 2:04 AM
🧬 🦠 🏙️
Urban vs rural lifestyles create dramatically different gut microbiomes. But how do these different gut microbiomes affect the host?
Excited to share our new paper: www.biorxiv.org/content/10.1...
Urban vs rural lifestyles create dramatically different gut microbiomes. But how do these different gut microbiomes affect the host?
Excited to share our new paper: www.biorxiv.org/content/10.1...
Reposted by Christian Diener
LorBin: efficient binning of long-read metagenomes by multiscale adaptive clustering and evaluation. #LongRead #Metagenomics #MAGs #BinningMethods #UnsupervisedBinning @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 3, 2025 at 12:15 PM
LorBin: efficient binning of long-read metagenomes by multiscale adaptive clustering and evaluation. #LongRead #Metagenomics #MAGs #BinningMethods #UnsupervisedBinning @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Christian Diener
Great to see this finally published!
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
Abstract. Metagenomic sequencing enables the in-depth study of microbes and their functions in humans, animals, and the environment. While sequencing data
academic.oup.com
October 31, 2025 at 3:16 PM
Great to see this finally published!
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Reposted by Christian Diener
Can you take a quarter cup of composite sewage, simply ask ‘what’s in there?’, and find out all of the pathogens circulating in that community?
That is the question we asked in our latest pre-print.
Turns out you can.
1/
www.medrxiv.org/content/10.1...
That is the question we asked in our latest pre-print.
Turns out you can.
1/
www.medrxiv.org/content/10.1...
Untargeted longitudinal ultra deep metagenomic sequencing of wastewater provides a comprehensive readout of expected and unexpected viral pathogens
Wastewater surveillance has become a powerful tool to monitor circulating viruses at a community level. Currently, most wastewater surveillance efforts use target-based approaches such as quantitative...
www.medrxiv.org
October 31, 2025 at 12:19 PM
Can you take a quarter cup of composite sewage, simply ask ‘what’s in there?’, and find out all of the pathogens circulating in that community?
That is the question we asked in our latest pre-print.
Turns out you can.
1/
www.medrxiv.org/content/10.1...
That is the question we asked in our latest pre-print.
Turns out you can.
1/
www.medrxiv.org/content/10.1...
Reposted by Christian Diener
Looks interesting 👀: Distinguishing diet- and microbe-derived metabolites in the human gut microbiomejournal.biomedcentral.com/articles/10....
Distinguishing diet- and microbe-derived metabolites in the human gut - Microbiome
Background Human gut microbes metabolize food and host secretions, consuming and producing small molecules that are important to health and homeostasis. Here, we present an atlas of diet- and microbio...
microbiomejournal.biomedcentral.com
October 18, 2025 at 7:07 PM
Looks interesting 👀: Distinguishing diet- and microbe-derived metabolites in the human gut microbiomejournal.biomedcentral.com/articles/10....
Reposted by Christian Diener
Come and do a PhD with me! Are you looking for a PhD project at the intersection of #microbiome and #food science? This project, in collaboration with ADM milling, will explore novel microbiome targeted food ingredients
🎓 #PhDPosition !
🍽️ The impact of innovative food ingredients on the human gut microbiome and health with Dr Fred Warren @starchlab.bsky.social
📅Apply by 2 December
➡️ buff.ly/k1KEcfL
🍽️ The impact of innovative food ingredients on the human gut microbiome and health with Dr Fred Warren @starchlab.bsky.social
📅Apply by 2 December
➡️ buff.ly/k1KEcfL
October 14, 2025 at 4:01 PM
Come and do a PhD with me! Are you looking for a PhD project at the intersection of #microbiome and #food science? This project, in collaboration with ADM milling, will explore novel microbiome targeted food ingredients
Reposted by Christian Diener
Thinking about a postdoc in microbiome science?
Our lab at the MPI for Biology (Tübingen) builds on the culture I established at Cornell: collaborative, creative, and internationally diverse. Postdocs lead their own projects with secure funding. Join us!
#PostdocJobs #HostMicrobe #AcademicJobs
Our lab at the MPI for Biology (Tübingen) builds on the culture I established at Cornell: collaborative, creative, and internationally diverse. Postdocs lead their own projects with secure funding. Join us!
#PostdocJobs #HostMicrobe #AcademicJobs
October 4, 2025 at 5:37 PM
Thinking about a postdoc in microbiome science?
Our lab at the MPI for Biology (Tübingen) builds on the culture I established at Cornell: collaborative, creative, and internationally diverse. Postdocs lead their own projects with secure funding. Join us!
#PostdocJobs #HostMicrobe #AcademicJobs
Our lab at the MPI for Biology (Tübingen) builds on the culture I established at Cornell: collaborative, creative, and internationally diverse. Postdocs lead their own projects with secure funding. Join us!
#PostdocJobs #HostMicrobe #AcademicJobs
Reposted by Christian Diener
On Friday, Episode #110 of #MattersMicrobial became available. The brilliant Dr. Sean Gibbons joined the #QualityQuorum to describe what the microbiome can tell us about numbers, nutrients, and health. I learned so much. Sean is the #MicrobiomeWhisperer. @microbe.tv
youtu.be/wdwTma0gV4k?...
youtu.be/wdwTma0gV4k?...
October 5, 2025 at 7:10 PM
On Friday, Episode #110 of #MattersMicrobial became available. The brilliant Dr. Sean Gibbons joined the #QualityQuorum to describe what the microbiome can tell us about numbers, nutrients, and health. I learned so much. Sean is the #MicrobiomeWhisperer. @microbe.tv
youtu.be/wdwTma0gV4k?...
youtu.be/wdwTma0gV4k?...
Reposted by Christian Diener
This morning, @isbscience.org's Dr. Mary Brunkow was awarded the 2025 Nobel Prize in Physiology or Medicine! Dr. Brunkow shares the award with Fred Ramsdell and Shimon Sakaguchi. Read the press release here: www.nobelprize.org/.../medicine....
What a tremendous honor! Congratulations!
What a tremendous honor! Congratulations!
October 6, 2025 at 4:19 PM
This morning, @isbscience.org's Dr. Mary Brunkow was awarded the 2025 Nobel Prize in Physiology or Medicine! Dr. Brunkow shares the award with Fred Ramsdell and Shimon Sakaguchi. Read the press release here: www.nobelprize.org/.../medicine....
What a tremendous honor! Congratulations!
What a tremendous honor! Congratulations!
Reposted by Christian Diener
Excited to share our @cp-cellhostmicrobe.bsky.social led by Magda showing how Bif has co-evolved with different animal hosts 🐒🐭🐷🐦
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Bifido adaptations across hosts
@halllab.bsky.social survey insects, reptiles, birds & mammals to uncover how Bifidobacterium adapts to hosts. Bifidobacterium & host exhibit strong co-phylogenetic associations, driven by vertical transmission & dietary selection
www.cell.com/cell-host-mi...
@halllab.bsky.social survey insects, reptiles, birds & mammals to uncover how Bifidobacterium adapts to hosts. Bifidobacterium & host exhibit strong co-phylogenetic associations, driven by vertical transmission & dietary selection
www.cell.com/cell-host-mi...
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts
Bifidobacterium are beneficial members of the microbiota across animal hosts. Kujawska
et al. demonstrate that bifidobacteria have likely co-evolved more closely with mammals,
particularly primates, a...
www.cell.com
September 11, 2025 at 2:49 PM
Excited to share our @cp-cellhostmicrobe.bsky.social led by Magda showing how Bif has co-evolved with different animal hosts 🐒🐭🐷🐦
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Reposted by Christian Diener
Fecal filtrate is less effective than donor stool (FMT) for the treatment of C. difficile recurrence. Now shown in a multicentre trial, out today in @lancetgastrohep.bsky.social .
Congratulations to Dina Kao @ualberta.bsky.social & team!
Gift link:
authors.elsevier.com/c/1lphg8nByr...
Congratulations to Dina Kao @ualberta.bsky.social & team!
Gift link:
authors.elsevier.com/c/1lphg8nByr...
authors.elsevier.com
September 23, 2025 at 9:38 AM
Fecal filtrate is less effective than donor stool (FMT) for the treatment of C. difficile recurrence. Now shown in a multicentre trial, out today in @lancetgastrohep.bsky.social .
Congratulations to Dina Kao @ualberta.bsky.social & team!
Gift link:
authors.elsevier.com/c/1lphg8nByr...
Congratulations to Dina Kao @ualberta.bsky.social & team!
Gift link:
authors.elsevier.com/c/1lphg8nByr...
Reposted by Christian Diener
New to @nextflow.io?✨Join us for Nextflow Training all of next week!
Work through instructor-led videos and hands-on exercises at your own pace. Plus, the chance to earn an official completion certificate. 🎓
👉 Register now: hubs.la/Q03Jf_Zp0
Work through instructor-led videos and hands-on exercises at your own pace. Plus, the chance to earn an official completion certificate. 🎓
👉 Register now: hubs.la/Q03Jf_Zp0
September 15, 2025 at 9:00 AM
New to @nextflow.io?✨Join us for Nextflow Training all of next week!
Work through instructor-led videos and hands-on exercises at your own pace. Plus, the chance to earn an official completion certificate. 🎓
👉 Register now: hubs.la/Q03Jf_Zp0
Work through instructor-led videos and hands-on exercises at your own pace. Plus, the chance to earn an official completion certificate. 🎓
👉 Register now: hubs.la/Q03Jf_Zp0
Reposted by Christian Diener
The next @nextflow.io Training Week is coming up - September 2025 📆
Grab the opportunity to book some time in your calendar and pester some of the nice Seqera folks who will be around to help out in the training office hours 😊
Grab the opportunity to book some time in your calendar and pester some of the nice Seqera folks who will be around to help out in the training office hours 😊
🚀 Nextflow Training Week is back on Sep 22-26! 💻 This self-paced online training features on-demand walkthrough videos and support via office hours and the community forum!
🔗 Register now: hubs.la/Q03HWK4L0
🔗 Register now: hubs.la/Q03HWK4L0
September 11, 2025 at 8:38 AM
The next @nextflow.io Training Week is coming up - September 2025 📆
Grab the opportunity to book some time in your calendar and pester some of the nice Seqera folks who will be around to help out in the training office hours 😊
Grab the opportunity to book some time in your calendar and pester some of the nice Seqera folks who will be around to help out in the training office hours 😊
Reposted by Christian Diener
💥Personalized C. difficile colonization risk prediction and probiotic therapy assessment in the human gut💥
I'm very excited about this work, driven by Alex Carr & co-supervised by @cdiener.com
@cp-cellsystems.bsky.social @isbscience.org @nitinbaliga.bsky.social
www.cell.com/cell-systems...
🧵...
I'm very excited about this work, driven by Alex Carr & co-supervised by @cdiener.com
@cp-cellsystems.bsky.social @isbscience.org @nitinbaliga.bsky.social
www.cell.com/cell-systems...
🧵...
Personalized Clostridioides difficile colonization risk prediction and probiotic therapy assessment in the human gut
Carr et al. show how microbial community-scale metabolic models (MCMMs) predict personalized
Clostridioides difficile colonization risk and probiotic efficacy. MCMMs reveal key
metabolic strategies ex...
www.cell.com
August 6, 2025 at 4:51 PM
💥Personalized C. difficile colonization risk prediction and probiotic therapy assessment in the human gut💥
I'm very excited about this work, driven by Alex Carr & co-supervised by @cdiener.com
@cp-cellsystems.bsky.social @isbscience.org @nitinbaliga.bsky.social
www.cell.com/cell-systems...
🧵...
I'm very excited about this work, driven by Alex Carr & co-supervised by @cdiener.com
@cp-cellsystems.bsky.social @isbscience.org @nitinbaliga.bsky.social
www.cell.com/cell-systems...
🧵...
Reposted by Christian Diener
Out in @natbiotech.nature.com: Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. Profiles of 700,000 metagenomes at sandpiper.qut.edu.au. A 🧵
July 16, 2025 at 9:59 PM
Out in @natbiotech.nature.com: Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. Profiles of 700,000 metagenomes at sandpiper.qut.edu.au. A 🧵
Reposted by Christian Diener
New RESOURCE!
Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria
@arzamasovalex.bsky.social @drlarsbode.bsky.social Andrei Osterman, Jeff Gordon & co
#microbiomesky #microsky
www.nature.com/articles/s41...
Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria
@arzamasovalex.bsky.social @drlarsbode.bsky.social Andrei Osterman, Jeff Gordon & co
#microbiomesky #microsky
www.nature.com/articles/s41...
Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria - Nature Microbiology
A comprehensive genomic analysis reveals species- and strain-level heterogeneity in carbohydrate utilization potential across bifidobacteria of human origin.
www.nature.com
July 16, 2025 at 11:31 AM
New RESOURCE!
Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria
@arzamasovalex.bsky.social @drlarsbode.bsky.social Andrei Osterman, Jeff Gordon & co
#microbiomesky #microsky
www.nature.com/articles/s41...
Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria
@arzamasovalex.bsky.social @drlarsbode.bsky.social Andrei Osterman, Jeff Gordon & co
#microbiomesky #microsky
www.nature.com/articles/s41...
@kl-fil.bsky.social will be presenting her work in our lab tomorrow in the @femsmicro.org poster session. Definitely check it out if you're there! 🦠🧬+💻=♥️
Tomorrow, I will be presenting a poster 081.16P about mucin degrading specialists of the ✨Akkermansia✨ genus in patients that underwent 💩 transplants to treat their ulcerative colitis. Come for a chat, and pls give me feedback on my version of designing with microbes but only on paper 🙃
#FEMS2025
#FEMS2025
July 16, 2025 at 5:05 PM
@kl-fil.bsky.social will be presenting her work in our lab tomorrow in the @femsmicro.org poster session. Definitely check it out if you're there! 🦠🧬+💻=♥️
Reposted by Christian Diener
This is my first time attending a big @femsmicro.org congress #FEMS2025 (thank you @cdiener.com 💚). I wanted to experience the FEMS congress since my baby PhD days in 2019 but did not get a chance to until now. It is absolutely exceeding my expectations, and I will tell you exactly why in the 🧵
July 15, 2025 at 4:40 PM
This is my first time attending a big @femsmicro.org congress #FEMS2025 (thank you @cdiener.com 💚). I wanted to experience the FEMS congress since my baby PhD days in 2019 but did not get a chance to until now. It is absolutely exceeding my expectations, and I will tell you exactly why in the 🧵
Reposted by Christian Diener
Just published in @femsjournals.bsky.social🦠:
Akkermansia muciniphila, Ruminococcus torques and Bacteroides thetaiotaomicron differ in their preferences for degradation of porcine gastric mucin O- and N-glycans.
#microsky #microbiomesky #glycotime @mib-wur.bsky.social
doi.org/10.1093/fems...
Akkermansia muciniphila, Ruminococcus torques and Bacteroides thetaiotaomicron differ in their preferences for degradation of porcine gastric mucin O- and N-glycans.
#microsky #microbiomesky #glycotime @mib-wur.bsky.social
doi.org/10.1093/fems...
Distinct in vitro utilization and degradation of porcine gastric mucin glycans by human intestinal bacteria
The degradation and utilization of mucin glycans depend on microbial composition and the interactions between the present bacteria.
doi.org
July 15, 2025 at 12:59 PM
Just published in @femsjournals.bsky.social🦠:
Akkermansia muciniphila, Ruminococcus torques and Bacteroides thetaiotaomicron differ in their preferences for degradation of porcine gastric mucin O- and N-glycans.
#microsky #microbiomesky #glycotime @mib-wur.bsky.social
doi.org/10.1093/fems...
Akkermansia muciniphila, Ruminococcus torques and Bacteroides thetaiotaomicron differ in their preferences for degradation of porcine gastric mucin O- and N-glycans.
#microsky #microbiomesky #glycotime @mib-wur.bsky.social
doi.org/10.1093/fems...
Reposted by Christian Diener
Bluesky is now giving notifications for likes on reposts to the reposter. Excited that this may help folks recognize how high engagement is here.
Just a reminder that reposts are critical here without the algorithm. Late reposts are especially helpful for those who log in infrequently.
Just a reminder that reposts are critical here without the algorithm. Late reposts are especially helpful for those who log in infrequently.
July 10, 2025 at 11:33 AM
Bluesky is now giving notifications for likes on reposts to the reposter. Excited that this may help folks recognize how high engagement is here.
Just a reminder that reposts are critical here without the algorithm. Late reposts are especially helpful for those who log in infrequently.
Just a reminder that reposts are critical here without the algorithm. Late reposts are especially helpful for those who log in infrequently.
Reposted by Christian Diener
CeMESS is hiring!
Join us at the Division of Terrestrial Ecosystem Research (@ter-cemess.bsky.social) as Full Professor of SOIL ECOSYSTEMS AND GLOBAL CHANGE. Collaborate across a leading institution in microbiome science and environmental research.
🔗 Learn more: cemess.univie.ac.at/news/detail-...
Join us at the Division of Terrestrial Ecosystem Research (@ter-cemess.bsky.social) as Full Professor of SOIL ECOSYSTEMS AND GLOBAL CHANGE. Collaborate across a leading institution in microbiome science and environmental research.
🔗 Learn more: cemess.univie.ac.at/news/detail-...
We are hiring: Full Professor of Soil Ecosystems and Global Change
Soil ecosystems form the foundation of planetary health and play a critical role in climate feedback mechanisms. However, they are also vulnerable to the impacts of global change.
cemess.univie.ac.at
July 7, 2025 at 9:37 AM
CeMESS is hiring!
Join us at the Division of Terrestrial Ecosystem Research (@ter-cemess.bsky.social) as Full Professor of SOIL ECOSYSTEMS AND GLOBAL CHANGE. Collaborate across a leading institution in microbiome science and environmental research.
🔗 Learn more: cemess.univie.ac.at/news/detail-...
Join us at the Division of Terrestrial Ecosystem Research (@ter-cemess.bsky.social) as Full Professor of SOIL ECOSYSTEMS AND GLOBAL CHANGE. Collaborate across a leading institution in microbiome science and environmental research.
🔗 Learn more: cemess.univie.ac.at/news/detail-...