Anna (Ania) Bajur 🧬
@annbajur.bsky.social
Loving everything forces, polarity, metabolism/lipids and immune cells related
Postdoc Spillane lab @ ImperialLifeSci (previously KCL Physics)
🧬💗 🔬
Alumna: MPI-CBG, IIMCB Poland
Professional human 🏃♀️⛰️
Postdoc Spillane lab @ ImperialLifeSci (previously KCL Physics)
🧬💗 🔬
Alumna: MPI-CBG, IIMCB Poland
Professional human 🏃♀️⛰️
Reposted by Anna (Ania) Bajur 🧬
www.nature.com/articles/s41...
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy - Nature
Acetyl-coenzyme A functions as a non-canonical signal to trigger mitophagy, and the acetyl-coenzyme A–NLRX1 axis underlies the KRAS-inhibitor-induced mitophagy response and promotes drug resistan...
www.nature.com
November 12, 2025 at 6:02 PM
www.nature.com/articles/s41...
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Reposted by Anna (Ania) Bajur 🧬
A game changer in our hands... www.nature.com/articles/s41...
Universal consensus 3D segmentation of cells from 2D segmented stacks - Nature Methods
u-Segment3D is a universal framework that translates and enhances 2D instance segmentations to a 3D consensus instance segmentation without training data. It performs well across diverse datasets, inc...
www.nature.com
November 11, 2025 at 6:48 PM
A game changer in our hands... www.nature.com/articles/s41...
Reposted by Anna (Ania) Bajur 🧬
Thrilled to announce the launch of my lab
@cri-utsw.bsky.social at UTSW this January!
We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.
@cri-utsw.bsky.social at UTSW this January!
We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.
We're growing! Our newest Investigator @henrydebelly.bsky.social will join the CRI Tissue #Regeneration Program in January 2026. Learn more about Henry ➡️ cri.utsw.edu/faculty/henr... and 📌apply to research in his lab cri.utsw.edu/careers
October 16, 2025 at 10:00 PM
Thrilled to announce the launch of my lab
@cri-utsw.bsky.social at UTSW this January!
We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.
@cri-utsw.bsky.social at UTSW this January!
We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.
Reposted by Anna (Ania) Bajur 🧬
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
October 15, 2025 at 6:33 AM
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
Reposted by Anna (Ania) Bajur 🧬
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
Reposted by Anna (Ania) Bajur 🧬
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 2:06 PM
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Reposted by Anna (Ania) Bajur 🧬
Cell-surface DNA - wowser!
🧬❤️
🧬❤️
We’re excited to report work led by postdoc Jennifer Porat in the lab, finding that DNA accumulates on the surface of living cells and that the secreted extracellular protein DNASE1L3 can modulate its levels on B and T cells. With a new twist for ATAC-seq as well www.biorxiv.org/content/10.1...
DNASE1L3 surveils mitochondrial DNA on the surface of distinct mammalian cells
The extracellular space is a critical environment for discriminating self versus non-self nucleic acids and initiating the appropriate immune responses through signaling cascades to relay information ...
www.biorxiv.org
October 8, 2025 at 1:15 PM
Cell-surface DNA - wowser!
🧬❤️
🧬❤️
Reposted by Anna (Ania) Bajur 🧬
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 6, 2025 at 5:52 PM
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Anna (Ania) Bajur 🧬
#Micorscopy community, does anyone know where I can order this type of bottle from? Or even what the proper name is for them?
October 1, 2025 at 3:07 PM
#Micorscopy community, does anyone know where I can order this type of bottle from? Or even what the proper name is for them?
Reposted by Anna (Ania) Bajur 🧬
Our new paper, in collaboration with Bristol Myers Squibb, on a Natural Killer cell immune therapy, is just published here:
www.pnas.org/doi/10.1073/...
#immunesynapse #nkcells #immunetherapy #microscopy
www.pnas.org/doi/10.1073/...
#immunesynapse #nkcells #immunetherapy #microscopy
Nanoscale restructuring of the immune synapse with an engager enhances NK cell function | PNAS
Engagers are antibody-based therapies which bind immune cell receptors and a target
cell ligand. Next-gen engagers typically bind two activating re...
www.pnas.org
September 19, 2025 at 3:57 PM
Our new paper, in collaboration with Bristol Myers Squibb, on a Natural Killer cell immune therapy, is just published here:
www.pnas.org/doi/10.1073/...
#immunesynapse #nkcells #immunetherapy #microscopy
www.pnas.org/doi/10.1073/...
#immunesynapse #nkcells #immunetherapy #microscopy
Reposted by Anna (Ania) Bajur 🧬
Check out this excellent paper from Khodor Hazime and @dandavis101.bsky.social! It's got NK cells, it's got engagers, plus super-resolution microscopy!
Our new paper is out! Khodor Hazime led the brilliant work at the @dandavis101.bsky.social lab that shows *how* engagers that bring NK cell receptors together at the immune synapse boost activation against tumour cells
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
September 19, 2025 at 4:33 PM
Check out this excellent paper from Khodor Hazime and @dandavis101.bsky.social! It's got NK cells, it's got engagers, plus super-resolution microscopy!
Reposted by Anna (Ania) Bajur 🧬
'Novartis is buying the rights to potential cardiovascular medicines from a Chinese biotech in a deal worth up to $5.2bn, as big pharmaceutical companies become increasingly reliant on Chinese innovation to replenish their drug pipelines.'
Novartis strikes deal worth up to $5.2bn for Chinese cardio drug rights
Argo Biopharma collaboration adds to record total this year spent by big pharma on treatments from Chinese companies
www.ft.com
September 4, 2025 at 11:29 PM
'Novartis is buying the rights to potential cardiovascular medicines from a Chinese biotech in a deal worth up to $5.2bn, as big pharmaceutical companies become increasingly reliant on Chinese innovation to replenish their drug pipelines.'
Reposted by Anna (Ania) Bajur 🧬
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
This is such a great work! Congratulations to everyone 🥳🥳🥳
August 20, 2025 at 4:35 PM
This is such a great work! Congratulations to everyone 🥳🥳🥳
Reposted by Anna (Ania) Bajur 🧬
Durable B-Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
Objectives Ocrelizumab (OCR), a humanized anti-CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR-MS). We assessed early cellular B-cell profiles in patients...
onlinelibrary.wiley.com
August 13, 2025 at 3:02 PM
Durable B-Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Anna (Ania) Bajur 🧬
✨We’ve just launched our new guide to #vaccinations during #pregnancy!
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
August 6, 2025 at 10:16 AM
✨We’ve just launched our new guide to #vaccinations during #pregnancy!
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
Understand how immunity changes, which vaccines the NHS recommends, and how they protect both parent and baby during pregnancy and beyond.
Download a copy for trusted information: bit.ly/4fuRqVw
Reposted by Anna (Ania) Bajur 🧬
Engineering B cells to treat and study human disease
www.nature.com/articles/s41... @natbiotech.nature.com
www.nature.com/articles/s41... @natbiotech.nature.com
August 5, 2025 at 3:18 PM
Engineering B cells to treat and study human disease
www.nature.com/articles/s41... @natbiotech.nature.com
www.nature.com/articles/s41... @natbiotech.nature.com
Reposted by Anna (Ania) Bajur 🧬
How do lipids shape life? I explore this question in my recent talk for the Build-a-Cell 🦠 seminar series. Thanks to @kateadamala.bsky.social for hosting! Watch it here: youtu.be/JnF7hPCiSbI?...
Build-a-Cell seminar James Saenz: Harnessing minimal cells to understand the living membranes
YouTube video by Build-a-Cell
youtu.be
July 8, 2025 at 8:01 AM
How do lipids shape life? I explore this question in my recent talk for the Build-a-Cell 🦠 seminar series. Thanks to @kateadamala.bsky.social for hosting! Watch it here: youtu.be/JnF7hPCiSbI?...
Reposted by Anna (Ania) Bajur 🧬
We’re excited to share a new pre-print from the lab! Led by Carmen Ramirez Moncayo and a fantastic collaboration with several groups from across @mrc-lms.bsky.social & @imperialcollegeldn.bsky.social. Interested in #OvarianCancer, #PARPinhibitors or #DrugDistribution? please read on! bit.ly/45lpekS
June 11, 2025 at 8:11 PM
We’re excited to share a new pre-print from the lab! Led by Carmen Ramirez Moncayo and a fantastic collaboration with several groups from across @mrc-lms.bsky.social & @imperialcollegeldn.bsky.social. Interested in #OvarianCancer, #PARPinhibitors or #DrugDistribution? please read on! bit.ly/45lpekS
Reposted by Anna (Ania) Bajur 🧬
Very glad and honored to contribute to this cool study. Check out the latest story on my favorite protein "NINJ1": www.nature.com/articles/s41...
June 9, 2025 at 3:49 PM
Very glad and honored to contribute to this cool study. Check out the latest story on my favorite protein "NINJ1": www.nature.com/articles/s41...
Reposted by Anna (Ania) Bajur 🧬
This Friday, UK Cell Motility Club symposium in Cambridge, UK: exciting PhD student and Postdoc speaker line up! A few last minute spots available. Follow us on @uk-cmc.bsky.social
cytoskeleton.wixsite.com/londoncellmo...
cytoskeleton.wixsite.com/londoncellmo...
HOME | londoncellmotility
cytoskeleton.wixsite.com
June 10, 2025 at 10:56 AM
This Friday, UK Cell Motility Club symposium in Cambridge, UK: exciting PhD student and Postdoc speaker line up! A few last minute spots available. Follow us on @uk-cmc.bsky.social
cytoskeleton.wixsite.com/londoncellmo...
cytoskeleton.wixsite.com/londoncellmo...
I did my PhD using flies as a model system🩷. FlyBase is amazing, without it my PhD would be much more painful. I can’t imagine it stopping its existence 😥. Sharing for greater reach! Please donate 🙏
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 5:44 PM
I did my PhD using flies as a model system🩷. FlyBase is amazing, without it my PhD would be much more painful. I can’t imagine it stopping its existence 😥. Sharing for greater reach! Please donate 🙏
Reposted by Anna (Ania) Bajur 🧬
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏
youtu.be/8YhJM6zxYDw?...
youtu.be/8YhJM6zxYDw?...
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
youtu.be
May 24, 2025 at 1:13 AM
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏
youtu.be/8YhJM6zxYDw?...
youtu.be/8YhJM6zxYDw?...
Reposted by Anna (Ania) Bajur 🧬
Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse @pnas.org @katelynspillane.bsky.social
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
May 23, 2025 at 3:52 AM
Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse @pnas.org @katelynspillane.bsky.social
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Anna (Ania) Bajur 🧬
Here come our new palette of fluorescent dyes. The BD dyes endeaves to balance glowy brightness, robust photostability, and biocompatibility. Let's boost 4D dynamic super-resolution imaging!!!
www.nature.com/articles/s41...
@spirochrome.com
www.nature.com/articles/s41...
@spirochrome.com
A palette of bridged bicycle-strengthened fluorophores - Nature Methods
A suite of bridged rhodamine dyes (BriDyes) offers excellent brightness, solubility, photostability, and tunable cell permeability along with resistance to photoblueing, making them exceptional all-pu...
www.nature.com
May 20, 2025 at 2:11 PM
Here come our new palette of fluorescent dyes. The BD dyes endeaves to balance glowy brightness, robust photostability, and biocompatibility. Let's boost 4D dynamic super-resolution imaging!!!
www.nature.com/articles/s41...
@spirochrome.com
www.nature.com/articles/s41...
@spirochrome.com