Katerina Akassoglou - Akassoglou Lab
@akassogloulab.bsky.social
We study neurovascular mechanisms of inflammation and tissue repair
Akassogloulab.org
Akassogloulab.org
Reposted by Katerina Akassoglou - Akassoglou Lab
Thrilled to share that I received the NoA for my first R01 “Mechanisms of pathogenic microglial populations in CNS inflammation”. Major milestone for the Lab. Extremely grateful for SS/SRO, PO and everyone else at NINDS for their continued support. Photo of my lab, wife and son, celebrating!
August 6, 2025 at 11:17 PM
Thrilled to share that I received the NoA for my first R01 “Mechanisms of pathogenic microglial populations in CNS inflammation”. Major milestone for the Lab. Extremely grateful for SS/SRO, PO and everyone else at NINDS for their continued support. Photo of my lab, wife and son, celebrating!
Reposted by Katerina Akassoglou - Akassoglou Lab
#AAIC25 day 2 in full swing here in Toronto!! Fascinating morning sessions, and a fantastic plenary talk by @akassogloulab.bsky.social on neurovascular interaction mechanisms!!! Now another plenary talk about heterogeneous tauopathy presentation by the eminent Prof Maria Grazia Spillantini!!
July 28, 2025 at 3:49 PM
#AAIC25 day 2 in full swing here in Toronto!! Fascinating morning sessions, and a fantastic plenary talk by @akassogloulab.bsky.social on neurovascular interaction mechanisms!!! Now another plenary talk about heterogeneous tauopathy presentation by the eminent Prof Maria Grazia Spillantini!!
Reposted by Katerina Akassoglou - Akassoglou Lab
#AAIC25 attendees, don’t miss today's plenary session at 11 a.m., featuring
🟣 Maria Grazia Spillantini, Ph.D., Professor, Molecular Neurology in the Clinical School, University of Cambridge.
🟣 @akassogloulab.bsky.social, Professor, Department of Neurology, University of California, San Francisco
🟣 Maria Grazia Spillantini, Ph.D., Professor, Molecular Neurology in the Clinical School, University of Cambridge.
🟣 @akassogloulab.bsky.social, Professor, Department of Neurology, University of California, San Francisco
July 28, 2025 at 2:01 PM
#AAIC25 attendees, don’t miss today's plenary session at 11 a.m., featuring
🟣 Maria Grazia Spillantini, Ph.D., Professor, Molecular Neurology in the Clinical School, University of Cambridge.
🟣 @akassogloulab.bsky.social, Professor, Department of Neurology, University of California, San Francisco
🟣 Maria Grazia Spillantini, Ph.D., Professor, Molecular Neurology in the Clinical School, University of Cambridge.
🟣 @akassogloulab.bsky.social, Professor, Department of Neurology, University of California, San Francisco
Reposted by Katerina Akassoglou - Akassoglou Lab
Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...
July 14, 2025 at 10:09 AM
Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...
Reposted by Katerina Akassoglou - Akassoglou Lab
Gladstone scientist Zhaoqi Yan received an award for postdocs who show exceptional creativity in neuroscience. He will use it to study blood-brain barrier dysfunction and its impact on neurological disease.
@akassogloulab.bsky.social
bit.ly/3EZT4R9
@akassogloulab.bsky.social
bit.ly/3EZT4R9
Zhaoqi Yan Named a 2025 Warren Alpert Distinguished Scholar
Gladstone researcher receives prize to study blood-brain barrier dysfunction and its impact on neurological disease.
bit.ly
May 13, 2025 at 3:34 PM
Gladstone scientist Zhaoqi Yan received an award for postdocs who show exceptional creativity in neuroscience. He will use it to study blood-brain barrier dysfunction and its impact on neurological disease.
@akassogloulab.bsky.social
bit.ly/3EZT4R9
@akassogloulab.bsky.social
bit.ly/3EZT4R9
Insightful Review by Gabriele De Luca at @ox.ac.uk discussing BBB permeability and fibrin deposition driving neuroinflammation, gliosis & neurodegeneration as a shared pathogenic cascade & therapeutic target among neurological diseases.
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
March 22, 2025 at 7:13 PM
Insightful Review by Gabriele De Luca at @ox.ac.uk discussing BBB permeability and fibrin deposition driving neuroinflammation, gliosis & neurodegeneration as a shared pathogenic cascade & therapeutic target among neurological diseases.
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
Great Session today at 2025 Annual Meeting of the American Society for Experimental Neurotherapeutics (ASENT) on "Immunotherapy of Neurodegenerative Diseases". A tour-de-force talk by V. Wee Yong on extracellular matrix & remyelination. Thank you to the organizers & all for joining us!
March 12, 2025 at 8:25 PM
Great Session today at 2025 Annual Meeting of the American Society for Experimental Neurotherapeutics (ASENT) on "Immunotherapy of Neurodegenerative Diseases". A tour-de-force talk by V. Wee Yong on extracellular matrix & remyelination. Thank you to the organizers & all for joining us!
Reposted by Katerina Akassoglou - Akassoglou Lab
Congratulations to winners of The Brain Prize 2025!
Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience.
Learn more: brainprize.org/winners/canc...
Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience.
Learn more: brainprize.org/winners/canc...
March 5, 2025 at 3:37 PM
Congratulations to winners of The Brain Prize 2025!
Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience.
Learn more: brainprize.org/winners/canc...
Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience.
Learn more: brainprize.org/winners/canc...
Reposted by Katerina Akassoglou - Akassoglou Lab
Scientists worry that persistent cognitive issues caused by Covid signal that a surge in dementia cases and other mental conditions is on the horizon.
Gift link to my updated explainer on what we know about Covid’s impact on the brain ⬇️
tinyurl.com/yrpwkf2n
Gift link to my updated explainer on what we know about Covid’s impact on the brain ⬇️
tinyurl.com/yrpwkf2n
What We Know About Covid’s Impact on Your Brain
Scientists worry that persistent cognitive issues caused by Covid signal that a surge in dementia cases and other mental conditions is on the horizon.
tinyurl.com
March 4, 2025 at 3:27 AM
Scientists worry that persistent cognitive issues caused by Covid signal that a surge in dementia cases and other mental conditions is on the horizon.
Gift link to my updated explainer on what we know about Covid’s impact on the brain ⬇️
tinyurl.com/yrpwkf2n
Gift link to my updated explainer on what we know about Covid’s impact on the brain ⬇️
tinyurl.com/yrpwkf2n
Congrats to Zhaoqi Yan postdoc fellow @akassogloulab.bsky.social for his selection for the 2025 Warren Alpert Distinguished Scholar Fellowship! Grateful to Warren Alpert Foundation for supporting Zhaoqi’s exciting research on blood-brain barrier & neurodegeneration! www.warrenalpertfoundation.org
March 4, 2025 at 1:28 AM
Congrats to Zhaoqi Yan postdoc fellow @akassogloulab.bsky.social for his selection for the 2025 Warren Alpert Distinguished Scholar Fellowship! Grateful to Warren Alpert Foundation for supporting Zhaoqi’s exciting research on blood-brain barrier & neurodegeneration! www.warrenalpertfoundation.org
Reposted by Katerina Akassoglou - Akassoglou Lab
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
NIH funding freeze stalls applications on $1.5 billion in medical research funds
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
www.npr.org
February 22, 2025 at 6:39 PM
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
Reposted by Katerina Akassoglou - Akassoglou Lab
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.
https://go.nature.com/4gM6oW4
https://go.nature.com/4gM6oW4
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
go.nature.com
February 20, 2025 at 8:04 PM
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.
https://go.nature.com/4gM6oW4
https://go.nature.com/4gM6oW4
Reposted by Katerina Akassoglou - Akassoglou Lab
The neuroimmune connectome in health and disease
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The neuroimmune connectome in health and disease - Nature
A review of studies on communication between the nervous and immune systems redefines the neuroimmune connectome with a focus on health and disease, and discusses how the latest techniques can advance...
www.nature.com
February 12, 2025 at 5:27 PM
The neuroimmune connectome in health and disease
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Andrew Park & Lauren Le undergraduates @ucberkeleyofficial.bsky.social joined our lab @gladstoneinst.bsky.social for their research training! Grateful to all members of my lab for supporting the training of 21 amazing undergrads todate & their enthusiasm introducing young scientists to research!
February 13, 2025 at 9:05 PM
Andrew Park & Lauren Le undergraduates @ucberkeleyofficial.bsky.social joined our lab @gladstoneinst.bsky.social for their research training! Grateful to all members of my lab for supporting the training of 21 amazing undergrads todate & their enthusiasm introducing young scientists to research!
Congrats to Zhaoqi Yan & Jae Kyu Ryu for receiving the 2024 Gladstone Award for Scientific Excellence, to Zhaoqi for the Dormal Best Paper Prize & Pilar Alzamora for the GIND Award of Excellence! Thank you gladstoneinst.bsky.social for recognizing the scientific achievements of this amazing team!
February 13, 2025 at 8:11 AM
Congrats to Zhaoqi Yan & Jae Kyu Ryu for receiving the 2024 Gladstone Award for Scientific Excellence, to Zhaoqi for the Dormal Best Paper Prize & Pilar Alzamora for the GIND Award of Excellence! Thank you gladstoneinst.bsky.social for recognizing the scientific achievements of this amazing team!
Congratulations to Hisao Miyajima postdoctoral fellow @akassogloulab.bsky.social @gladstoneinst.bsky.social and UCSF for being awarded a NMSS Postdoctoral Fellowship to study mechanisms of progression in Multiple Sclerosis. So proud of his accomplishment!
February 1, 2025 at 3:41 PM
Congratulations to Hisao Miyajima postdoctoral fellow @akassogloulab.bsky.social @gladstoneinst.bsky.social and UCSF for being awarded a NMSS Postdoctoral Fellowship to study mechanisms of progression in Multiple Sclerosis. So proud of his accomplishment!
Reposted by Katerina Akassoglou - Akassoglou Lab
🚨 CNS barriers scientists...come join us for #cshlbbb 2025! Submit your abstracts by January 24th...we pick MANY talks from abstracts - we look forward to seeing you in April!
![adult mouse leptomeninges - VE-cadherin (magenta) labeling junctions between endothelial cells in brain vasculature and between pial cells - blue nuclei [DAPI]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ghkjazitflwyaczzoo6mwmld/bafkreihjnjs7spk2irftwcvjccbvx3ya7bmmqx4ii6itvgtruja6a66s54@jpeg)
January 23, 2025 at 9:24 PM
🚨 CNS barriers scientists...come join us for #cshlbbb 2025! Submit your abstracts by January 24th...we pick MANY talks from abstracts - we look forward to seeing you in April!
Reposted by Katerina Akassoglou - Akassoglou Lab
An elegant study by Katerina Akassoglou and colleagues
has illuminated our understanding of the role of fibrin (component of blood clots), SARS-CoV-2, and brain inflammation in Covid/Long Covid.
A new Ground Truths podcast, w/transcript. Open-access.
erictopol.substack.com/p/katerina-a...
has illuminated our understanding of the role of fibrin (component of blood clots), SARS-CoV-2, and brain inflammation in Covid/Long Covid.
A new Ground Truths podcast, w/transcript. Open-access.
erictopol.substack.com/p/katerina-a...
October 19, 2024 at 5:14 PM
An elegant study by Katerina Akassoglou and colleagues
has illuminated our understanding of the role of fibrin (component of blood clots), SARS-CoV-2, and brain inflammation in Covid/Long Covid.
A new Ground Truths podcast, w/transcript. Open-access.
erictopol.substack.com/p/katerina-a...
has illuminated our understanding of the role of fibrin (component of blood clots), SARS-CoV-2, and brain inflammation in Covid/Long Covid.
A new Ground Truths podcast, w/transcript. Open-access.
erictopol.substack.com/p/katerina-a...
Grateful to the National Multiple Scerosis Society for supporting new ideas for basic research in neuroimmunology leading to new therapies for MS & neurological diseases. www.linkedin.com/posts/nation...
National MS Society on LinkedIn: Breakthroughs in MS research are occurring every year. Dr. Katarina…
Breakthroughs in MS research are occurring every year. Dr. Katarina Akassoglou, winner of the Barancik Prize in 2019, is researching aids against…
www.linkedin.com
January 19, 2025 at 4:24 AM
Grateful to the National Multiple Scerosis Society for supporting new ideas for basic research in neuroimmunology leading to new therapies for MS & neurological diseases. www.linkedin.com/posts/nation...
Reposted by Katerina Akassoglou - Akassoglou Lab
Our lab at Yale U/Wu Tsai Institute has a postdoctoral position on neurodegeneration, neuro-glial-vascular biology using 2photon, calcium/voltage imaging, gene editing,transcriptome/proteome, 3D EM, translational neurosci/chemistry. Email me if interested. Forward to those interested pls
January 8, 2025 at 10:08 PM
Our lab at Yale U/Wu Tsai Institute has a postdoctoral position on neurodegeneration, neuro-glial-vascular biology using 2photon, calcium/voltage imaging, gene editing,transcriptome/proteome, 3D EM, translational neurosci/chemistry. Email me if interested. Forward to those interested pls
Reposted by Katerina Akassoglou - Akassoglou Lab
A really 🔥 topic ! "The pathobiology of neurovascular aging" www.cell.com/neuron/fullt... #cerebrovascular
The pathobiology of neurovascular aging
As the population ages, neurovascular pathologies have become leading causes of death and disability. Santisteban and Iadecola review data showing that neurovascular aging not only reduces cerebral blood flow but also impairs protein clearance, immune function, and neurotrophic homeostasis, thereby increasing the risk of stroke, vascular dementia, and Alzheimer’s disease.
www.cell.com
January 8, 2025 at 4:46 PM
A really 🔥 topic ! "The pathobiology of neurovascular aging" www.cell.com/neuron/fullt... #cerebrovascular
Reposted by Katerina Akassoglou - Akassoglou Lab
🧠 How COVID-19 impacts the brain
Researchers found that blood clots linked to COVID-19 can cause inflammation and brain damage.
A new antibody treatment targeting these clots could help reduce long-term effects seen in long COVID.
🔗 www.nature.com/articles/s41...
#SciComm #COVID19 🧪
Researchers found that blood clots linked to COVID-19 can cause inflammation and brain damage.
A new antibody treatment targeting these clots could help reduce long-term effects seen in long COVID.
🔗 www.nature.com/articles/s41...
#SciComm #COVID19 🧪
Fibrin drives thromboinflammation and neuropathology in COVID-19 - Nature
Fibrin drives inflammation and neuropathology in SARS-CoV-2 infection, and fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with long COVID.
www.nature.com
December 31, 2024 at 11:43 AM
🧠 How COVID-19 impacts the brain
Researchers found that blood clots linked to COVID-19 can cause inflammation and brain damage.
A new antibody treatment targeting these clots could help reduce long-term effects seen in long COVID.
🔗 www.nature.com/articles/s41...
#SciComm #COVID19 🧪
Researchers found that blood clots linked to COVID-19 can cause inflammation and brain damage.
A new antibody treatment targeting these clots could help reduce long-term effects seen in long COVID.
🔗 www.nature.com/articles/s41...
#SciComm #COVID19 🧪
Reposted by Katerina Akassoglou - Akassoglou Lab
Interested in using functional genomics to understand the brain in health and disease?
Check out our Gordon research conference below! Slots for posters and short talks are still available! Deadline March 9th
www.grc.org/functional-g...
Check out our Gordon research conference below! Slots for posters and short talks are still available! Deadline March 9th
www.grc.org/functional-g...
2025 Functional Genomics of Human Brain Development and Disease Conference GRC
The 2025 Gordon Research Conference on Functional Genomics of Human Brain Development and Disease will be held in Ventura, California. Apply today to reserve your spot.
www.grc.org
January 7, 2025 at 10:21 PM
Interested in using functional genomics to understand the brain in health and disease?
Check out our Gordon research conference below! Slots for posters and short talks are still available! Deadline March 9th
www.grc.org/functional-g...
Check out our Gordon research conference below! Slots for posters and short talks are still available! Deadline March 9th
www.grc.org/functional-g...
Reposted by Katerina Akassoglou - Akassoglou Lab
Nice review highlighting the associations between neuropsychiatric conditions and #cerebrovascular deficits doi.org/10.1111/eci.... #BloodBrainBarrier #Psychiatry
Neurovascular dysfunction in psychiatric disorders: Underlying mechanisms and therapeutic approaches
The neurovascular unit (NVU) is present in both brain and retinal barriers and consists of endothelial cells, basement membrane, pericytes, glial cells (astrocytes and microglia) and neurons. Barrier...
doi.org
January 8, 2025 at 12:34 AM
Nice review highlighting the associations between neuropsychiatric conditions and #cerebrovascular deficits doi.org/10.1111/eci.... #BloodBrainBarrier #Psychiatry