Gladstone Institutes
@gladstoneinst.bsky.social
To drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and diverse environment.
Celebrating innovation in regenerative medicine! Congratulations to Rudolf Jaenisch, recipient of the 2025 Ogawa-Yamanaka Stem Cell Prize, for his pioneering work with induced pluripotent stem cells.
@whiteheadinstitute.bsky.social
@cp-cellstemcell.bsky.social
@whiteheadinstitute.bsky.social
@cp-cellstemcell.bsky.social
A sculptor of modern regenerative medicine
Editors’ note: The Ogawa-Yamanaka Stem Cell Prize recognizes groundbreaking work in translational regenerative medicine using reprogrammed cells. The prize is supported by Gladstone Institutes, in partnership with Cell Press. Among his myriad accomplishments, Rudolf Jaenisch—winner of the 2025 O...
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January 20, 2026 at 5:49 PM
Celebrating innovation in regenerative medicine! Congratulations to Rudolf Jaenisch, recipient of the 2025 Ogawa-Yamanaka Stem Cell Prize, for his pioneering work with induced pluripotent stem cells.
@whiteheadinstitute.bsky.social
@cp-cellstemcell.bsky.social
@whiteheadinstitute.bsky.social
@cp-cellstemcell.bsky.social
Reposted by Gladstone Institutes
From co-creating the first transgenic mice to showing the therapeutic potential of iPScs — adult skin or blood cells reprogrammed into an embryonic stem cell-like state — Jaenisch has helped shape modern regenerative medicine.
@cp-cellstemcell.bsky.social covers the journey: shorturl.at/qRxyj
@cp-cellstemcell.bsky.social covers the journey: shorturl.at/qRxyj
January 20, 2026 at 3:24 PM
From co-creating the first transgenic mice to showing the therapeutic potential of iPScs — adult skin or blood cells reprogrammed into an embryonic stem cell-like state — Jaenisch has helped shape modern regenerative medicine.
@cp-cellstemcell.bsky.social covers the journey: shorturl.at/qRxyj
@cp-cellstemcell.bsky.social covers the journey: shorturl.at/qRxyj
Who was a mentor that shaped your scientific journey? 👩🔬 🥼
Tell us your stories in the comments ⤵️ ⤵️
Tell us your stories in the comments ⤵️ ⤵️
January 19, 2026 at 9:17 PM
Who was a mentor that shaped your scientific journey? 👩🔬 🥼
Tell us your stories in the comments ⤵️ ⤵️
Tell us your stories in the comments ⤵️ ⤵️
👏 Applauding the winners of the Gladstone Awards!
Gladstone Celebrates brought our community together to recognize colleagues whose exceptional contributions power our science—both in the lab and behind the scenes.
Gladstone Celebrates brought our community together to recognize colleagues whose exceptional contributions power our science—both in the lab and behind the scenes.
January 16, 2026 at 9:15 PM
👏 Applauding the winners of the Gladstone Awards!
Gladstone Celebrates brought our community together to recognize colleagues whose exceptional contributions power our science—both in the lab and behind the scenes.
Gladstone Celebrates brought our community together to recognize colleagues whose exceptional contributions power our science—both in the lab and behind the scenes.
Reposted by Gladstone Institutes
January issue of @natcardiovascres.nature.com has our image on the cover! Also a research highlight on our paper @irfankathiriya.bsky.social @gladstoneinst.bsky.social @ucsfanesthesia.bsky.social www.nature.com/natcardiovas...
Nature Cardiovascular Research - TBX5 sets boundaries for a healthy heart
Kathiriya et al. identify a Tbx5 + /Mef2cAHF + cardiac progenitor lineage that demarcates the interventricular septum during development, and changes in this...
www.nature.com
January 16, 2026 at 4:31 PM
January issue of @natcardiovascres.nature.com has our image on the cover! Also a research highlight on our paper @irfankathiriya.bsky.social @gladstoneinst.bsky.social @ucsfanesthesia.bsky.social www.nature.com/natcardiovas...
At Gladstone, collaboration fuels discovery. Our partnership with Topos Bio brings together AI-powered protein modeling and Gladstone’s deep expertise in neurodegenerative disease to explore new therapeutic strategies for conditions like Parkinson’s and Alzheimer’s.
Press Release - Topos Bio
Topos Bio Secures $10.5M to Tackle 'Undruggable' Proteins Driving Alzheimer's and Cancer
bit.ly
January 15, 2026 at 9:07 PM
At Gladstone, collaboration fuels discovery. Our partnership with Topos Bio brings together AI-powered protein modeling and Gladstone’s deep expertise in neurodegenerative disease to explore new therapeutic strategies for conditions like Parkinson’s and Alzheimer’s.
January is National Mentoring Month, and we’re celebrating the people who make a lasting impact at every stage of a scientific journey.
Mentorship doesn’t just shape careers—it fuels curiosity, confidence, and a love of discovery.
Mentorship doesn’t just shape careers—it fuels curiosity, confidence, and a love of discovery.
January 14, 2026 at 6:08 PM
January is National Mentoring Month, and we’re celebrating the people who make a lasting impact at every stage of a scientific journey.
Mentorship doesn’t just shape careers—it fuels curiosity, confidence, and a love of discovery.
Mentorship doesn’t just shape careers—it fuels curiosity, confidence, and a love of discovery.
Steve Finkbeiner has been selected as an SLAS2026 Innovation Award finalist!
Steve will be presenting his work on the development and application of AI-powered label-free imaging for assays and screening at the SLAS2026 International Conference & Exhibition.
https://bit.ly/3NgUPgt
Steve will be presenting his work on the development and application of AI-powered label-free imaging for assays and screening at the SLAS2026 International Conference & Exhibition.
https://bit.ly/3NgUPgt
January 13, 2026 at 5:55 PM
Steve Finkbeiner has been selected as an SLAS2026 Innovation Award finalist!
Steve will be presenting his work on the development and application of AI-powered label-free imaging for assays and screening at the SLAS2026 International Conference & Exhibition.
https://bit.ly/3NgUPgt
Steve will be presenting his work on the development and application of AI-powered label-free imaging for assays and screening at the SLAS2026 International Conference & Exhibition.
https://bit.ly/3NgUPgt
An HIV diagnosis upended San Diego resident Jim Dunn’s life. But his willingness to participate in an end-of-life program is helping scientists to better understand the disease and hopefully find a cure.
Documentary sheds light on HIV patient's science-advancing ‘last gift' through UCSD study
‘The Last Gift: Jim's Courage, Our Hope' shares the story of late San Diego resident Jim Dunn and his role in research aiming to find a cure for HIV
bit.ly
January 12, 2026 at 9:19 PM
An HIV diagnosis upended San Diego resident Jim Dunn’s life. But his willingness to participate in an end-of-life program is helping scientists to better understand the disease and hopefully find a cure.
Reposted by Gladstone Institutes
Amazing hike in Marin Headlands with the @gladstoneinst.bsky.social hiking challenge group. 7 miles of gorgeous view. Now everything hurts.
January 10, 2026 at 11:10 PM
Amazing hike in Marin Headlands with the @gladstoneinst.bsky.social hiking challenge group. 7 miles of gorgeous view. Now everything hurts.
Alex Marson and his collaborators at Stanford University developed a genomic mapping technique that helps close the gap in understanding why certain genetic variants are tied to disease.
New study bridges the gap between genes and disease risk
These maps could clarify confusing biology and pinpoint disease-causing genes that are ripe for intervention.
bit.ly
January 11, 2026 at 6:25 PM
Alex Marson and his collaborators at Stanford University developed a genomic mapping technique that helps close the gap in understanding why certain genetic variants are tied to disease.
New year, new job. Check out these open positions at Gladstone 👇 👇
👩💼 Accounting Manager: https://bit.ly/4qOL2gc
🔬 Research Associate I- Conklin Lab: https://bit.ly/3NeeKwu
📝 Administrative Assistant: https://bit.ly/4aRCkcm
#ScienceJobs #BiotechJobs
👩💼 Accounting Manager: https://bit.ly/4qOL2gc
🔬 Research Associate I- Conklin Lab: https://bit.ly/3NeeKwu
📝 Administrative Assistant: https://bit.ly/4aRCkcm
#ScienceJobs #BiotechJobs
January 10, 2026 at 7:17 PM
New year, new job. Check out these open positions at Gladstone 👇 👇
👩💼 Accounting Manager: https://bit.ly/4qOL2gc
🔬 Research Associate I- Conklin Lab: https://bit.ly/3NeeKwu
📝 Administrative Assistant: https://bit.ly/4aRCkcm
#ScienceJobs #BiotechJobs
👩💼 Accounting Manager: https://bit.ly/4qOL2gc
🔬 Research Associate I- Conklin Lab: https://bit.ly/3NeeKwu
📝 Administrative Assistant: https://bit.ly/4aRCkcm
#ScienceJobs #BiotechJobs
Last year, we honored Rudolf Jaenisch, the 2025 recipient of the Ogawa-Yamanaka Stem Cell Prize.
Watch the award ceremony and his scientific lecture.
Watch the award ceremony and his scientific lecture.
Honoring Rudolf Jaenisch: 2025 Ogawa-Yamanaka Stem Cell Prize Ceremony & Lecture
On December 1, 2025, Gladstone Institutes honored Rudolf Jaenisch, MD, the 2025 recipient of the Ogawa-Yamanaka Stem Cell Prize. A pioneer in epigenetics and stem cell biology, Jaenisch’s discoveries have profoundly advanced our understanding of gene r...
bit.ly
January 9, 2026 at 8:45 PM
Last year, we honored Rudolf Jaenisch, the 2025 recipient of the Ogawa-Yamanaka Stem Cell Prize.
Watch the award ceremony and his scientific lecture.
Watch the award ceremony and his scientific lecture.
From fellowship support to global conference experiences, mentorship transforms careers. As we mark #NationalMentoringMonth, we celebrate the mentors whose belief and support ripple through generations of scientists. 🧬💛👩🔬
From Mentorship to Legacy: Creating Opportunity for Early Career Scientists
Robert and Linda Mahley’s commitment to trainee development continues through Gladstone’s annual Career Advancement Awards.
gladstone.org
January 8, 2026 at 8:49 PM
From fellowship support to global conference experiences, mentorship transforms careers. As we mark #NationalMentoringMonth, we celebrate the mentors whose belief and support ripple through generations of scientists. 🧬💛👩🔬
Explore the latest episode of the Stem Cell Podcast featuring Deepak Srivastava as he discusses groundbreaking research on heart defects in Down syndrome, innovative therapeutic strategies, and ways to accelerate cell and gene therapy development!
@stemcellpodcast.com
@stemcellpodcast.com
Ep. 311: "Congenital Heart Disease" Featuring Dr. Deepak Srivastava - The Stem Cell Podcast
Dr. Deepak Srivastava is the President of the Gladstone Institutes and Director of the Roddenberry Stem Cell Center. His lab is focused on the gene networks that guide cardiac development. He talks about their recent work investigating heart defects in Down syndrome and strategies
stemcellpodcast.com
January 6, 2026 at 6:10 PM
Explore the latest episode of the Stem Cell Podcast featuring Deepak Srivastava as he discusses groundbreaking research on heart defects in Down syndrome, innovative therapeutic strategies, and ways to accelerate cell and gene therapy development!
@stemcellpodcast.com
@stemcellpodcast.com
Reposted by Gladstone Institutes
Together with @ronghuizhu.bsky.social, we are thrilled to present our new perturb-seq study of 22M primary CD4+ T cells, across donors and timepoints – the result of a decade-long collaboration between the Marson @marsonlab.bsky.social and Pritchard @jkpritch.bsky.social labs 🧵 tinyurl.com/gwt2025
Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
Gene regulatory networks encode the fundamental logic of cellular functions, but systematic network mapping remains challenging, especially in cell states relevant to human biology and disease. Here, ...
tinyurl.com
January 5, 2026 at 6:42 PM
Together with @ronghuizhu.bsky.social, we are thrilled to present our new perturb-seq study of 22M primary CD4+ T cells, across donors and timepoints – the result of a decade-long collaboration between the Marson @marsonlab.bsky.social and Pritchard @jkpritch.bsky.social labs 🧵 tinyurl.com/gwt2025
Did you know you can listen to our articles on Spotify (or wherever you listen to podcasts?)
Check out this one and learn how scientists at Gladstone found a new method that could treat the majority of patients with Charcot-Marie-Tooth disease.
https://bit.ly/4987sSo
Check out this one and learn how scientists at Gladstone found a new method that could treat the majority of patients with Charcot-Marie-Tooth disease.
https://bit.ly/4987sSo
Spotify – Web Player
bit.ly
January 5, 2026 at 6:07 PM
Did you know you can listen to our articles on Spotify (or wherever you listen to podcasts?)
Check out this one and learn how scientists at Gladstone found a new method that could treat the majority of patients with Charcot-Marie-Tooth disease.
https://bit.ly/4987sSo
Check out this one and learn how scientists at Gladstone found a new method that could treat the majority of patients with Charcot-Marie-Tooth disease.
https://bit.ly/4987sSo
Reposted by Gladstone Institutes
📽 G&D Tapes 📽
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
December 19, 2025 at 6:02 PM
📽 G&D Tapes 📽
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
Reposted by Gladstone Institutes
Accepted ms on modeling human atrial disease posted @dev-journal.bsky.social just now. Congratulations to @irfankathiriya.bsky.social @jsauce7.bsky.social and team! @gladstoneinst.bsky.social @ucsfanesthesia.bsky.social journals.biologists.com/dev/article-...
Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease
While atrial septal defects (ASDs) and atrial fibrillation (AF) present differently, there is evidence that they share some genetic basis. Here, we used directed differentiation of human induced pluri...
journals.biologists.com
December 19, 2025 at 6:32 PM
Accepted ms on modeling human atrial disease posted @dev-journal.bsky.social just now. Congratulations to @irfankathiriya.bsky.social @jsauce7.bsky.social and team! @gladstoneinst.bsky.social @ucsfanesthesia.bsky.social journals.biologists.com/dev/article-...
Reposted by Gladstone Institutes
We're wrapping up 2025 with none other than Dr. Deepak Srivastava from @gladstoneinst.bsky.social!
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
December 19, 2025 at 10:20 PM
We're wrapping up 2025 with none other than Dr. Deepak Srivastava from @gladstoneinst.bsky.social!
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
Reposted by Gladstone Institutes
One gene can have hundreds of disease-causing mutations. Creating a separate gene therapy for each? Impractical. @gladstoneinst.bsky.social @ucsanfrancisco.bsky.social scientists developed "haplotype editing" to remove an entire mutated gene, a more efficient strategy. gladstone.org/news/gene-ed...
Gene Editing Strategy Could Treat Hundreds of Inherited Diseases More Effectively
Scientists at Gladstone show the new method could treat the majority of patients with Charcot-Marie-Tooth disease.
gladstone.org
December 19, 2025 at 11:54 PM
One gene can have hundreds of disease-causing mutations. Creating a separate gene therapy for each? Impractical. @gladstoneinst.bsky.social @ucsanfrancisco.bsky.social scientists developed "haplotype editing" to remove an entire mutated gene, a more efficient strategy. gladstone.org/news/gene-ed...
Reposted by Gladstone Institutes
Tune in to our latest episode!
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
December 23, 2025 at 10:05 PM
Tune in to our latest episode!
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
Reposted by Gladstone Institutes
Congratulations to Dr. Alan Baik on being selected for the American Society for Clinical Investigation 2026 Young Physician-Scientist Award, which honors early career physician-scientists nationwide for notable research achievements. #UCSFCardiology @gladstoneinst.bsky.social
January 2, 2026 at 6:48 PM
Congratulations to Dr. Alan Baik on being selected for the American Society for Clinical Investigation 2026 Young Physician-Scientist Award, which honors early career physician-scientists nationwide for notable research achievements. #UCSFCardiology @gladstoneinst.bsky.social
A discovery about the consequence of neuron overactivity could lead to new methods of treating or preventing Parkinson’s disease.
Overworked Brain Cells May Burn Out in Parkinson’s Disease
A discovery about the consequence of neuron overactivity could lead to new methods of treating or preventing Parkinson’s disease.
gladstone.org
January 3, 2026 at 7:54 PM
A discovery about the consequence of neuron overactivity could lead to new methods of treating or preventing Parkinson’s disease.
This past year was filled with scientific progress, meaningful connections, and moments that reminded us why research matters. Thank you to everyone who followed along, supported our work, and championed science with us.
We can’t wait to see what the new year brings.
We can’t wait to see what the new year brings.
January 1, 2026 at 3:53 PM
This past year was filled with scientific progress, meaningful connections, and moments that reminded us why research matters. Thank you to everyone who followed along, supported our work, and championed science with us.
We can’t wait to see what the new year brings.
We can’t wait to see what the new year brings.