Genes & Development
@genesdev.bsky.social
G&D publishes high-quality research in molecular biology, cancer biology, development, neuroscience and related fields. In addition, G&D also publishes comprehensive Review Articles, Perspectives and Outlooks written by leading scientists.
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🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review, and Research articles online now at Genes & Development. Also in this issue, an In Memoriam on the life and work of John B. Gurdon.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/23-24.toc
New Outlook, Review, and Research articles online now at Genes & Development. Also in this issue, an In Memoriam on the life and work of John B. Gurdon.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/23-24.toc
Best wishes and holiday cheer to our amazing G&D community...
December 24, 2025 at 7:00 PM
Best wishes and holiday cheer to our amazing G&D community...
⏪ G&D RECAP ⏪
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
December 24, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
⏪ G&D RECAP ⏪
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
December 23, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
⏪ G&D RECAP ⏪
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
December 22, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
📽 G&D Tapes 📽
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
December 19, 2025 at 6:02 PM
📽 G&D Tapes 📽
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
⏪ G&D RECAP ⏪
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
December 19, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
⏪ G&D RECAP ⏪
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
December 18, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
⏪ G&D RECAP ⏪
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
December 17, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
December 17, 2025 at 4:05 PM
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
December 17, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
⏪ G&D RECAP ⏪
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin
December 16, 2025 at 7:01 PM
⏪ G&D RECAP ⏪
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin
⏪ G&D RECAP ⏪
🗓️ February 2025
RESEARCH PAPER: LINE1 elements at distal junctions of rDNA repeats regulate nucleolar organization in human embryonic stem cells
By Ataei et al. and Miguel Ramalho-Santos
➡️ https://genesdev.cshlp.org/content/39/3-4/280.full
#retrotransposons #genome #chromosome
🗓️ February 2025
RESEARCH PAPER: LINE1 elements at distal junctions of rDNA repeats regulate nucleolar organization in human embryonic stem cells
By Ataei et al. and Miguel Ramalho-Santos
➡️ https://genesdev.cshlp.org/content/39/3-4/280.full
#retrotransposons #genome #chromosome
December 15, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ February 2025
RESEARCH PAPER: LINE1 elements at distal junctions of rDNA repeats regulate nucleolar organization in human embryonic stem cells
By Ataei et al. and Miguel Ramalho-Santos
➡️ https://genesdev.cshlp.org/content/39/3-4/280.full
#retrotransposons #genome #chromosome
🗓️ February 2025
RESEARCH PAPER: LINE1 elements at distal junctions of rDNA repeats regulate nucleolar organization in human embryonic stem cells
By Ataei et al. and Miguel Ramalho-Santos
➡️ https://genesdev.cshlp.org/content/39/3-4/280.full
#retrotransposons #genome #chromosome
⏪ G&D RECAP ⏪
🗓️ January 2025
REVIEW: Genetics and biology of pancreatic ductal adenocarcinoma
By Ying et al. and Ronald DePinho
➡️ https://genesdev.cshlp.org/content/39/1-2/36.full
#pancreaticcancer #PDAC #tumor #genetics #tumormicroenvironment #cancertherapy
🗓️ January 2025
REVIEW: Genetics and biology of pancreatic ductal adenocarcinoma
By Ying et al. and Ronald DePinho
➡️ https://genesdev.cshlp.org/content/39/1-2/36.full
#pancreaticcancer #PDAC #tumor #genetics #tumormicroenvironment #cancertherapy
December 12, 2025 at 6:52 PM
⏪ G&D RECAP ⏪
🗓️ January 2025
REVIEW: Genetics and biology of pancreatic ductal adenocarcinoma
By Ying et al. and Ronald DePinho
➡️ https://genesdev.cshlp.org/content/39/1-2/36.full
#pancreaticcancer #PDAC #tumor #genetics #tumormicroenvironment #cancertherapy
🗓️ January 2025
REVIEW: Genetics and biology of pancreatic ductal adenocarcinoma
By Ying et al. and Ronald DePinho
➡️ https://genesdev.cshlp.org/content/39/1-2/36.full
#pancreaticcancer #PDAC #tumor #genetics #tumormicroenvironment #cancertherapy
OUTLOOK: MEF2C networks in heart tube development
By Hassan Abdulrazzak and Mark Mercola
➡️ https://genesdev.cshlp.org/content/39/23-24/1397.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
#transcriptionfactor #embryonicdevelopment #heartdevelopment #cardiactract
By Hassan Abdulrazzak and Mark Mercola
➡️ https://genesdev.cshlp.org/content/39/23-24/1397.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
#transcriptionfactor #embryonicdevelopment #heartdevelopment #cardiactract
December 11, 2025 at 4:01 PM
OUTLOOK: MEF2C networks in heart tube development
By Hassan Abdulrazzak and Mark Mercola
➡️ https://genesdev.cshlp.org/content/39/23-24/1397.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
#transcriptionfactor #embryonicdevelopment #heartdevelopment #cardiactract
By Hassan Abdulrazzak and Mark Mercola
➡️ https://genesdev.cshlp.org/content/39/23-24/1397.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
#transcriptionfactor #embryonicdevelopment #heartdevelopment #cardiactract
RESEARCH PAPER: Mice carrying homologous human shelterin POT1-L259S mutation linked to lung fibrosis show a telomerase deficiency-like phenotype with telomere shortening with increasing mouse generations
By Sánchez-Vázquez et al & Maria Blasco
➡️ https://genesdev.cshlp.org/content/39/23-24/1490.full
By Sánchez-Vázquez et al & Maria Blasco
➡️ https://genesdev.cshlp.org/content/39/23-24/1490.full
December 10, 2025 at 4:01 PM
RESEARCH PAPER: Mice carrying homologous human shelterin POT1-L259S mutation linked to lung fibrosis show a telomerase deficiency-like phenotype with telomere shortening with increasing mouse generations
By Sánchez-Vázquez et al & Maria Blasco
➡️ https://genesdev.cshlp.org/content/39/23-24/1490.full
By Sánchez-Vázquez et al & Maria Blasco
➡️ https://genesdev.cshlp.org/content/39/23-24/1490.full
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
December 9, 2025 at 4:01 PM
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
RESEARCH PAPER: MEF2C controls segment-specific gene regulatory networks that direct heart tube morphogenesis
By Muncie-Vasic et al. and Benoit Bruneau
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau
#transcriptionfactor #embryodevelopment #cardiactract
By Muncie-Vasic et al. and Benoit Bruneau
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau
#transcriptionfactor #embryodevelopment #cardiactract
December 8, 2025 at 7:00 PM
RESEARCH PAPER: MEF2C controls segment-specific gene regulatory networks that direct heart tube morphogenesis
By Muncie-Vasic et al. and Benoit Bruneau
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau
#transcriptionfactor #embryodevelopment #cardiactract
By Muncie-Vasic et al. and Benoit Bruneau
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau
#transcriptionfactor #embryodevelopment #cardiactract
G&D Executive Editor, Dr. Eric Sawey is at #cellbio2025!
If you’d like to share your work with us or learn about the journal, drop by the CSHL Press booth or reach out at sawey@cshl.edu
#genesdev Cold Spring Harbor Laboratory Press
If you’d like to share your work with us or learn about the journal, drop by the CSHL Press booth or reach out at sawey@cshl.edu
#genesdev Cold Spring Harbor Laboratory Press
December 8, 2025 at 1:55 PM
G&D Executive Editor, Dr. Eric Sawey is at #cellbio2025!
If you’d like to share your work with us or learn about the journal, drop by the CSHL Press booth or reach out at sawey@cshl.edu
#genesdev Cold Spring Harbor Laboratory Press
If you’d like to share your work with us or learn about the journal, drop by the CSHL Press booth or reach out at sawey@cshl.edu
#genesdev Cold Spring Harbor Laboratory Press
REVIEW: Transcription quality control at the promoter-proximal checkpoint
By Daniel Blears and Jesper Svejstrup
➡️ https://genesdev.cshlp.org/content/39/23-24/1399.full
Jesper Svejstrup
Center for Gene Expression (CGEN)
#transcription #promoterproximalpausing #RNApolymerase #elongation #mRNA
By Daniel Blears and Jesper Svejstrup
➡️ https://genesdev.cshlp.org/content/39/23-24/1399.full
Jesper Svejstrup
Center for Gene Expression (CGEN)
#transcription #promoterproximalpausing #RNApolymerase #elongation #mRNA
December 5, 2025 at 4:01 PM
REVIEW: Transcription quality control at the promoter-proximal checkpoint
By Daniel Blears and Jesper Svejstrup
➡️ https://genesdev.cshlp.org/content/39/23-24/1399.full
Jesper Svejstrup
Center for Gene Expression (CGEN)
#transcription #promoterproximalpausing #RNApolymerase #elongation #mRNA
By Daniel Blears and Jesper Svejstrup
➡️ https://genesdev.cshlp.org/content/39/23-24/1399.full
Jesper Svejstrup
Center for Gene Expression (CGEN)
#transcription #promoterproximalpausing #RNApolymerase #elongation #mRNA
RESEARCH COMMUNICATION: A critical affinity window for IgSF proteins DIP-α and Dpr10 is required for proper motor neuron arborization
By Lopez et al. and Richard Mann
➡️ https://genesdev.cshlp.org/content/39/23-24/1426.full
#neuron #motorneuron #neurodevelopment #celladhesion #synapsis #Drosophila
By Lopez et al. and Richard Mann
➡️ https://genesdev.cshlp.org/content/39/23-24/1426.full
#neuron #motorneuron #neurodevelopment #celladhesion #synapsis #Drosophila
December 4, 2025 at 4:01 PM
RESEARCH COMMUNICATION: A critical affinity window for IgSF proteins DIP-α and Dpr10 is required for proper motor neuron arborization
By Lopez et al. and Richard Mann
➡️ https://genesdev.cshlp.org/content/39/23-24/1426.full
#neuron #motorneuron #neurodevelopment #celladhesion #synapsis #Drosophila
By Lopez et al. and Richard Mann
➡️ https://genesdev.cshlp.org/content/39/23-24/1426.full
#neuron #motorneuron #neurodevelopment #celladhesion #synapsis #Drosophila
RESEARCH PAPER: UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast
By Bartolutti et al. and Gloria Brar
➡️ https://genesdev.cshlp.org/content/39/23-24/1434.full
#aneuploidy #unfoldedproteinresponse #UPR #proteinfolding #proteostasis #yeast
By Bartolutti et al. and Gloria Brar
➡️ https://genesdev.cshlp.org/content/39/23-24/1434.full
#aneuploidy #unfoldedproteinresponse #UPR #proteinfolding #proteostasis #yeast
December 3, 2025 at 4:01 PM
RESEARCH PAPER: UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast
By Bartolutti et al. and Gloria Brar
➡️ https://genesdev.cshlp.org/content/39/23-24/1434.full
#aneuploidy #unfoldedproteinresponse #UPR #proteinfolding #proteostasis #yeast
By Bartolutti et al. and Gloria Brar
➡️ https://genesdev.cshlp.org/content/39/23-24/1434.full
#aneuploidy #unfoldedproteinresponse #UPR #proteinfolding #proteostasis #yeast
RESEARCH COMMUNICATION: Igf2 regulates early postnatal DPP4+ preadipocyte pool expansion
By Altun et. al and Siegfried Ussar
➡️ https://genesdev.cshlp.org/content/39/23-24/1414.full
#adipose #stemcells #adipogenesis #insulinsignaling #celldifferentiation #IGF
By Altun et. al and Siegfried Ussar
➡️ https://genesdev.cshlp.org/content/39/23-24/1414.full
#adipose #stemcells #adipogenesis #insulinsignaling #celldifferentiation #IGF
December 2, 2025 at 7:45 PM
RESEARCH COMMUNICATION: Igf2 regulates early postnatal DPP4+ preadipocyte pool expansion
By Altun et. al and Siegfried Ussar
➡️ https://genesdev.cshlp.org/content/39/23-24/1414.full
#adipose #stemcells #adipogenesis #insulinsignaling #celldifferentiation #IGF
By Altun et. al and Siegfried Ussar
➡️ https://genesdev.cshlp.org/content/39/23-24/1414.full
#adipose #stemcells #adipogenesis #insulinsignaling #celldifferentiation #IGF
Reposted by Genes & Development
This month’s cover of @genesdev.bsky.social has @j-muncie-vasic.bsky.social’s embryos all in a row! Paper and commentary in the issue genesdev.cshlp.org/content/39/2...
Cover Photo — November/December 2025, 39 (23-24)
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
December 1, 2025 at 4:05 PM
This month’s cover of @genesdev.bsky.social has @j-muncie-vasic.bsky.social’s embryos all in a row! Paper and commentary in the issue genesdev.cshlp.org/content/39/2...
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review, and Research articles online now at Genes & Development. Also in this issue, an In Memoriam on the life and work of John B. Gurdon.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/23-24.toc
New Outlook, Review, and Research articles online now at Genes & Development. Also in this issue, an In Memoriam on the life and work of John B. Gurdon.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/23-24.toc
December 1, 2025 at 4:02 PM
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review, and Research articles online now at Genes & Development. Also in this issue, an In Memoriam on the life and work of John B. Gurdon.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/23-24.toc
New Outlook, Review, and Research articles online now at Genes & Development. Also in this issue, an In Memoriam on the life and work of John B. Gurdon.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/23-24.toc
🌟G&D SPOTLIGHT 🌟
REVIEW: RNA granules: functional compartments or incidental condensates?
By Andrea Putnam, Laura Thomas and Geraldine Seydoux
➡️ https://genesdev.cshlp.org/content/37/9-10/354.abstract
#RNAmetabolism #RNAgranules #phaseseparation #RiboNucleoProteins #condensates
REVIEW: RNA granules: functional compartments or incidental condensates?
By Andrea Putnam, Laura Thomas and Geraldine Seydoux
➡️ https://genesdev.cshlp.org/content/37/9-10/354.abstract
#RNAmetabolism #RNAgranules #phaseseparation #RiboNucleoProteins #condensates
November 28, 2025 at 7:00 PM
🌟G&D SPOTLIGHT 🌟
REVIEW: RNA granules: functional compartments or incidental condensates?
By Andrea Putnam, Laura Thomas and Geraldine Seydoux
➡️ https://genesdev.cshlp.org/content/37/9-10/354.abstract
#RNAmetabolism #RNAgranules #phaseseparation #RiboNucleoProteins #condensates
REVIEW: RNA granules: functional compartments or incidental condensates?
By Andrea Putnam, Laura Thomas and Geraldine Seydoux
➡️ https://genesdev.cshlp.org/content/37/9-10/354.abstract
#RNAmetabolism #RNAgranules #phaseseparation #RiboNucleoProteins #condensates