Eric (“VJ”) Rubenstein
@vjrubenstein.bsky.social
Lucky me, lucky mud.
Cell biology. Protein quality control. Yeast. PUI.
Survivor and Severance superfan
He/him
Views my own, not my employer's
Cell biology. Protein quality control. Yeast. PUI.
Survivor and Severance superfan
He/him
Views my own, not my employer's
Pinned
Trump's NIH funding cuts halt Indiana's life-saving research | Opinion
If you’ve been to the doctor and received treatment, that treatment was very likely built on NIH-supported research.
www.indystar.com
I wrote about the harmful impacts of NIH funding cuts on the health and economy of Indiana.
www.indystar.com/story/opinio...
www.indystar.com/story/opinio...
Reposted by Eric (“VJ”) Rubenstein
Greetings! I decided to make a YouTube video of my AlphaFold workshop that I've given a few times in the past year. Caveats aside, people seem to find this useful for thinking about how to model protein interactions and how to interpret various AF outputs 1/2
www.youtube.com/watch?v=u63o...
www.youtube.com/watch?v=u63o...
David's AlphaFold WorkShop 2026
YouTube video by David Fay
www.youtube.com
January 2, 2026 at 11:03 PM
Greetings! I decided to make a YouTube video of my AlphaFold workshop that I've given a few times in the past year. Caveats aside, people seem to find this useful for thinking about how to model protein interactions and how to interpret various AF outputs 1/2
www.youtube.com/watch?v=u63o...
www.youtube.com/watch?v=u63o...
Reposted by Eric (“VJ”) Rubenstein
Here is the link for Helene's preferred charity. Family requests donations to the fight against pancreatic cancer in lieu of flowers
letswinpc.kindful.com
letswinpc.kindful.com
Let's Win Pancreatic Cancer | Kindful
letswinpc.kindful.com
December 22, 2025 at 8:40 PM
Here is the link for Helene's preferred charity. Family requests donations to the fight against pancreatic cancer in lieu of flowers
letswinpc.kindful.com
letswinpc.kindful.com
Reposted by Eric (“VJ”) Rubenstein
Helene was so giving to others about her battle, and went through to make it into maybe the top 1% of survivors of pancreatic cancer, before succumbing Dec 19, 2025 all while losing her father to it. She supported @letswinpc.org and the family asks for you to consider supporting them as well.💔
Pancreatic cancer survivor Helene Andrews-Polymenis and Dr. John Chabot discuss strategies for preparing for a Whipple procedure.
Preparing for a Whipple Procedure: A Roadmap for Patients and Caregivers
Pancreatic cancer survivor Helene Andrews-Polymenis and Dr. John Chabot discuss strategies for preparing for a Whipple procedure.
buff.ly
December 22, 2025 at 8:28 PM
Helene was so giving to others about her battle, and went through to make it into maybe the top 1% of survivors of pancreatic cancer, before succumbing Dec 19, 2025 all while losing her father to it. She supported @letswinpc.org and the family asks for you to consider supporting them as well.💔
Reposted by Eric (“VJ”) Rubenstein
Some absolutely beautiful artwork here! Really love to see #yeast #cerevisae representing so well in yet another category: #fineart
🍻🥖🩺🔬🧪🧬🎨
#YeastResearch
🍻🥖🩺🔬🧪🧬🎨
#YeastResearch
The 2025 Agar Art Contest winners have been selected! This year’s theme, “Microbes Make the World Go Round,” inspired 557 global entries—from food fermentation to antibiotic production. See the masterpieces and finalists! asm.org/press-releas... #agarart
December 19, 2025 at 12:41 AM
Some absolutely beautiful artwork here! Really love to see #yeast #cerevisae representing so well in yet another category: #fineart
🍻🥖🩺🔬🧪🧬🎨
#YeastResearch
🍻🥖🩺🔬🧪🧬🎨
#YeastResearch
Reposted by Eric (“VJ”) Rubenstein
Great Bluetorial thread by Yamuna Krishnan @krishnanyamuna.bsky.social on preprint “Organelles harbour pH gradients” recently published by her lab!
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 3:33 AM
Great Bluetorial thread by Yamuna Krishnan @krishnanyamuna.bsky.social on preprint “Organelles harbour pH gradients” recently published by her lab!
@authorbillsullivan.com Unfortunately, we will be traveling Wednesday night and will have to break our tradition of live watching the #Survivor49 finale. BUT, we should still make our winner predictions - you get first pick!
December 17, 2025 at 3:22 AM
@authorbillsullivan.com Unfortunately, we will be traveling Wednesday night and will have to break our tradition of live watching the #Survivor49 finale. BUT, we should still make our winner predictions - you get first pick!
Reposted by Eric (“VJ”) Rubenstein
Old Man vs the SEA
December 14, 2025 at 10:41 PM
Old Man vs the SEA
Reposted by Eric (“VJ”) Rubenstein
Our membership drives ends THIS MONDAY, December 15th! Don’t delay in getting new sign-ups! Winners will be sent discount codes following this date.
December 14, 2025 at 2:40 AM
Our membership drives ends THIS MONDAY, December 15th! Don’t delay in getting new sign-ups! Winners will be sent discount codes following this date.
Reposted by Eric (“VJ”) Rubenstein
Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6...
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
December 12, 2025 at 3:53 PM
Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6...
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
Reposted by Eric (“VJ”) Rubenstein
I rarely ask for things, but I will make an exception for my colleague and friend, Augustine Goba, who dedicated his life to saving others.
Augustine was Director of the hemorrhagic fever lab in Kenema, Salone, and is struggling with PSP.
Please consider donating.
www.gofundme.com/f/augustine-...
Augustine was Director of the hemorrhagic fever lab in Kenema, Salone, and is struggling with PSP.
Please consider donating.
www.gofundme.com/f/augustine-...
Donate to Help Augustine Goba battle Progressive Supranuclear Palsy, organized by Michelle McGraw
Mr. Augustine Goba is the Emeritus Director of the Kenema Gov… Michelle McGraw needs your support for Help Augustine Goba battle Progressive Supranuclear Palsy
www.gofundme.com
December 13, 2025 at 12:29 AM
I rarely ask for things, but I will make an exception for my colleague and friend, Augustine Goba, who dedicated his life to saving others.
Augustine was Director of the hemorrhagic fever lab in Kenema, Salone, and is struggling with PSP.
Please consider donating.
www.gofundme.com/f/augustine-...
Augustine was Director of the hemorrhagic fever lab in Kenema, Salone, and is struggling with PSP.
Please consider donating.
www.gofundme.com/f/augustine-...
Reposted by Eric (“VJ”) Rubenstein
Happy to see our News & Views is out! We highlight two landmark papers demonstrating the potential for therapeutic targeting of FSP1 and #ferroptosis in in vivo cancer models. Beautiful work from @ubellackerlab.bsky.social, Thales Papagiannakopoulos, and colleagues. 🥳
www.nature.com/articles/s41...
www.nature.com/articles/s41...
In vivo models bring FSP1 inhibitors to life - Nature Cell Biology
FSP1 is a key suppressor of lipid peroxidation and ferroptosis, yet it is largely dispensable in standard cell culture models. Two new studies now show that FSP1 becomes essential for tumour growth in...
www.nature.com
December 12, 2025 at 4:15 PM
Happy to see our News & Views is out! We highlight two landmark papers demonstrating the potential for therapeutic targeting of FSP1 and #ferroptosis in in vivo cancer models. Beautiful work from @ubellackerlab.bsky.social, Thales Papagiannakopoulos, and colleagues. 🥳
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The Schuldiner lab’s most impressive (or at least cutest) library yet!
As many of us 🎁 things up for the year, make sure all your ℹ️'s are dotted- and all your #yeast emojis are downloaded! If you haven't yet, make sure to add the emojyeast collection to all your 📱💻🖥️⌚️
mayaschuldiner.wixsite.com/schuldinerla...
Thanks to the amazing Schuldiner lab for these!
mayaschuldiner.wixsite.com/schuldinerla...
Thanks to the amazing Schuldiner lab for these!
December 13, 2025 at 12:49 AM
The Schuldiner lab’s most impressive (or at least cutest) library yet!
Reposted by Eric (“VJ”) Rubenstein
You can do this right now:
Think of a person who wrote a paper you love, whose work influenced or helped you, or has made your professional life better.
Search up their email address. Shoot them a quick email of thanks. It means so, so much. This is a rough time of year, share some joy.
Think of a person who wrote a paper you love, whose work influenced or helped you, or has made your professional life better.
Search up their email address. Shoot them a quick email of thanks. It means so, so much. This is a rough time of year, share some joy.
December 11, 2025 at 10:08 PM
You can do this right now:
Think of a person who wrote a paper you love, whose work influenced or helped you, or has made your professional life better.
Search up their email address. Shoot them a quick email of thanks. It means so, so much. This is a rough time of year, share some joy.
Think of a person who wrote a paper you love, whose work influenced or helped you, or has made your professional life better.
Search up their email address. Shoot them a quick email of thanks. It means so, so much. This is a rough time of year, share some joy.
Reposted by Eric (“VJ”) Rubenstein
How’s the #yeast community closing out 2025? SGD is saying a heartfelt farewell, revealing new Resource links, announcing a simple way to support the #Database you rely on, and more. Read our December newsletter: www.yeastgenome.org/blog/sgd-new... #SGD #science
December 12, 2025 at 1:34 AM
How’s the #yeast community closing out 2025? SGD is saying a heartfelt farewell, revealing new Resource links, announcing a simple way to support the #Database you rely on, and more. Read our December newsletter: www.yeastgenome.org/blog/sgd-new... #SGD #science
If you're at #CellBio2025, please join us tomorrow at 9AM in Room 122 for a fantastic speaker lineup at the #EndoplasmicReticulum Minisymposium!
Immediately following our session will be the keynote presentations by Eva Nogales & Jennifer Lippincott-Schwartz!
@ascbiology.bsky.social
Immediately following our session will be the keynote presentations by Eva Nogales & Jennifer Lippincott-Schwartz!
@ascbiology.bsky.social
December 10, 2025 at 1:51 AM
If you're at #CellBio2025, please join us tomorrow at 9AM in Room 122 for a fantastic speaker lineup at the #EndoplasmicReticulum Minisymposium!
Immediately following our session will be the keynote presentations by Eva Nogales & Jennifer Lippincott-Schwartz!
@ascbiology.bsky.social
Immediately following our session will be the keynote presentations by Eva Nogales & Jennifer Lippincott-Schwartz!
@ascbiology.bsky.social
Congratulations to lab member Katie, whose Ball State Aspire Undergrad Research Grant was funded today!
I'm proud of how Katie persevered through writing - & rewriting - her proposal!
Looking forward to the work she will do to continue unraveling the genetic requirements for ER PQC!
I'm proud of how Katie persevered through writing - & rewriting - her proposal!
Looking forward to the work she will do to continue unraveling the genetic requirements for ER PQC!
December 8, 2025 at 11:05 PM
Congratulations to lab member Katie, whose Ball State Aspire Undergrad Research Grant was funded today!
I'm proud of how Katie persevered through writing - & rewriting - her proposal!
Looking forward to the work she will do to continue unraveling the genetic requirements for ER PQC!
I'm proud of how Katie persevered through writing - & rewriting - her proposal!
Looking forward to the work she will do to continue unraveling the genetic requirements for ER PQC!
Reposted by Eric (“VJ”) Rubenstein
#CellBio2025 Note that the app won’t list you as an attendee unless you manually add yourself to the list using your Profile link (under the little wheelie tool) @peiferlabunc.bsky.social @danstarrucdavis.bsky.social
December 7, 2025 at 4:18 PM
#CellBio2025 Note that the app won’t list you as an attendee unless you manually add yourself to the list using your Profile link (under the little wheelie tool) @peiferlabunc.bsky.social @danstarrucdavis.bsky.social
Reposted by Eric (“VJ”) Rubenstein
Hope to see you all at 10AM today!
If you're at #cellbio2025, @atmolines.bsky.social Hernan Garcia and I invite you to attend our Minisymposium “Physical Cell Biology from Molecules to Organisms” for incredible talks on epigenetic mechanical memory, viscoelasticity, cortical flows, morphogenesis, tissue wetting, size scaling, et al!
December 7, 2025 at 2:19 PM
Hope to see you all at 10AM today!
Reposted by Eric (“VJ”) Rubenstein
Another wonderful undergraduate poster session at the Mentored Undergraduate Research Showcase at #ASCB #CellBio2025. Bravo! And if you are at the meeting in Philly, check out those folks' posters at the main poster sessions!
December 7, 2025 at 2:46 AM
Another wonderful undergraduate poster session at the Mentored Undergraduate Research Showcase at #ASCB #CellBio2025. Bravo! And if you are at the meeting in Philly, check out those folks' posters at the main poster sessions!
Reposted by Eric (“VJ”) Rubenstein
Wonderful panel on what we can do about science denial at ASCB 2025 with Ken Miller and Michael Mann @michaelemann.bsky.social
December 6, 2025 at 9:07 PM
Wonderful panel on what we can do about science denial at ASCB 2025 with Ken Miller and Michael Mann @michaelemann.bsky.social
Reposted by Eric (“VJ”) Rubenstein
Just one week away until #CellBio2025!
Please plan to join us for a sUPeR speakER lineup at the #EndoplasmicReticulum Minisymposium!
Dec 10 at 9 AM
@ascbiology.bsky.social
Please plan to join us for a sUPeR speakER lineup at the #EndoplasmicReticulum Minisymposium!
Dec 10 at 9 AM
@ascbiology.bsky.social
Check out our @ascbiology.bsky.social #CellBio2025 Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself!
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
December 6, 2025 at 12:46 PM
2025 Rubenstein Lab Holiday party! ⛄🎄
I am so fortunate to work with such a hard-working, collaborative, and fun team of student scientists. 🔬
Of course, Basil thought the lab party was all about him (honestly, any party Basil is at *is* all about him). 🐾
I am so fortunate to work with such a hard-working, collaborative, and fun team of student scientists. 🔬
Of course, Basil thought the lab party was all about him (honestly, any party Basil is at *is* all about him). 🐾
December 3, 2025 at 8:28 PM
2025 Rubenstein Lab Holiday party! ⛄🎄
I am so fortunate to work with such a hard-working, collaborative, and fun team of student scientists. 🔬
Of course, Basil thought the lab party was all about him (honestly, any party Basil is at *is* all about him). 🐾
I am so fortunate to work with such a hard-working, collaborative, and fun team of student scientists. 🔬
Of course, Basil thought the lab party was all about him (honestly, any party Basil is at *is* all about him). 🐾
Reposted by Eric (“VJ”) Rubenstein
Today, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published:
journals.biologists.com/jcs/article/...
The result of a fantastic Iwasa-Drubin lab collaboration.
@margotriggi.bsky.social @jiwasa.bsky.social
movie.biologists.com/video/10.124...
journals.biologists.com/jcs/article/...
The result of a fantastic Iwasa-Drubin lab collaboration.
@margotriggi.bsky.social @jiwasa.bsky.social
movie.biologists.com/video/10.124...
December 2, 2025 at 9:02 PM
Today, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published:
journals.biologists.com/jcs/article/...
The result of a fantastic Iwasa-Drubin lab collaboration.
@margotriggi.bsky.social @jiwasa.bsky.social
movie.biologists.com/video/10.124...
journals.biologists.com/jcs/article/...
The result of a fantastic Iwasa-Drubin lab collaboration.
@margotriggi.bsky.social @jiwasa.bsky.social
movie.biologists.com/video/10.124...
Reposted by Eric (“VJ”) Rubenstein
New preprint out! We show that PROTAC-induced ubiquitination can bypass canonical ERAD to degrade ER membrane proteins. Wonderful collaboration w/ @dannomura.bsky.social and huge credit to grad student superstar Sydney Tomlinson!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Induced ubiquitination bypasses canonical ERAD to drive ER protein degradation
Heterobifunctional proteolysis-targeting chimeras (PROTACs) have emerged as a powerful strategy to degrade disease-relevant proteins, enabling targeting of previously "undruggable" proteins. Current d...
www.biorxiv.org
December 1, 2025 at 5:14 PM
New preprint out! We show that PROTAC-induced ubiquitination can bypass canonical ERAD to degrade ER membrane proteins. Wonderful collaboration w/ @dannomura.bsky.social and huge credit to grad student superstar Sydney Tomlinson!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Eric (“VJ”) Rubenstein
On this #GivingTuesday please consider ABRCMS, one of the most significant and effective conferences to propel scientists toward PhD programs and careers in science.
Support the ABRCMS 2026 Student Travel Award Fund! @asm.org
abrcms.activehosted.com/p_v.php?l=3&...
Support the ABRCMS 2026 Student Travel Award Fund! @asm.org
abrcms.activehosted.com/p_v.php?l=3&...
❤️ It's Giving Tuesday: Support ABRCMS 2026 Student Travel Award Fund
Fund the Future of Science...
abrcms.activehosted.com
December 2, 2025 at 4:43 PM
On this #GivingTuesday please consider ABRCMS, one of the most significant and effective conferences to propel scientists toward PhD programs and careers in science.
Support the ABRCMS 2026 Student Travel Award Fund! @asm.org
abrcms.activehosted.com/p_v.php?l=3&...
Support the ABRCMS 2026 Student Travel Award Fund! @asm.org
abrcms.activehosted.com/p_v.php?l=3&...