Susan Hafenstein
@suhafenstein.bsky.social
Reposted by Susan Hafenstein
Impressive work!
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
January 18, 2025 at 1:31 PM
Impressive work!
Reposted by Susan Hafenstein
Reposted by Susan Hafenstein
Protein production for cryoEM structure determination just got a lot cheaper - high resolution structure from half a plate of HEK cells with the "MIcro ISolation (MISO)" microfluidics-based approach. Congrats to the Brunner and Efremov labs in Brussels! www.biorxiv.org/content/10.1...
January 16, 2025 at 10:57 PM
Protein production for cryoEM structure determination just got a lot cheaper - high resolution structure from half a plate of HEK cells with the "MIcro ISolation (MISO)" microfluidics-based approach. Congrats to the Brunner and Efremov labs in Brussels! www.biorxiv.org/content/10.1...
Reposted by Susan Hafenstein
David Goodsell's work (and career) are such an inspiration. So many of us have experienced the molecular world through his brush🖌️👨🎨🫶. I'm happy to see @jiwasa.bsky.social picking up the torch for @rcsbpdb.bsky.social's "Molecule of the Month"🧪🧶🧬
At the heart of biology is the mantra: structure dictates function.Biological structures are also beautiful in their intricacy. David Goodsell brought this into public view. As he leaves "Molecule of the Month". here's a huge thank you for helping me see more clearly🧪1/2
cdn.rcsb.org/rcsb-pdb/gen...
cdn.rcsb.org/rcsb-pdb/gen...
January 7, 2025 at 8:46 AM
David Goodsell's work (and career) are such an inspiration. So many of us have experienced the molecular world through his brush🖌️👨🎨🫶. I'm happy to see @jiwasa.bsky.social picking up the torch for @rcsbpdb.bsky.social's "Molecule of the Month"🧪🧶🧬
Reposted by Susan Hafenstein
Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍
Preprint📜: www.biorxiv.org/content/10.1...
A short thread🧵👇
Preprint📜: www.biorxiv.org/content/10.1...
A short thread🧵👇
January 6, 2025 at 11:19 AM
Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍
Preprint📜: www.biorxiv.org/content/10.1...
A short thread🧵👇
Preprint📜: www.biorxiv.org/content/10.1...
A short thread🧵👇
Reposted by Susan Hafenstein
From The Lab Party - happy holidays to all!
December 15, 2024 at 1:44 PM
From The Lab Party - happy holidays to all!
Reposted by Susan Hafenstein
Delighted by this year's return to form for my lab, winning the fancy dress competition at the @cvrinfo.bsky.social Christmas party. The theme was music and we chose to go as "Guns and Roses"
December 11, 2024 at 8:48 AM
Delighted by this year's return to form for my lab, winning the fancy dress competition at the @cvrinfo.bsky.social Christmas party. The theme was music and we chose to go as "Guns and Roses"
Reposted by Susan Hafenstein
David Baker visits all the Rosetta folks after his Nobel lecture. And photo of all three Chemistry laureates - David Baker, Demis Hassabis, and John Jumper. An honor to be here in Stockholm to see this.
December 8, 2024 at 12:47 PM
David Baker visits all the Rosetta folks after his Nobel lecture. And photo of all three Chemistry laureates - David Baker, Demis Hassabis, and John Jumper. An honor to be here in Stockholm to see this.
Reposted by Susan Hafenstein
Hello Bluesky!
We're the Plevka Lab, a structural virology research group at CEITEC. Using techniques like SPA #cryo-EM and #cryo-ET 🔬, we explore the fascinating structures of viruses to uncover their secrets. Follow us for research updates, insights, and a glimpse into the world of #virology! 🧫 🦠
We're the Plevka Lab, a structural virology research group at CEITEC. Using techniques like SPA #cryo-EM and #cryo-ET 🔬, we explore the fascinating structures of viruses to uncover their secrets. Follow us for research updates, insights, and a glimpse into the world of #virology! 🧫 🦠
December 6, 2024 at 1:32 PM
Reposted by Susan Hafenstein
An incredible photo posted today by French President Emmanuel Macron.
The floor of Notre Dame Cathedral is filled with the workers involved in the 5 year project to restore the building following the devastating fire in 2019.
1/2
The floor of Notre Dame Cathedral is filled with the workers involved in the 5 year project to restore the building following the devastating fire in 2019.
1/2
November 29, 2024 at 6:26 PM
An incredible photo posted today by French President Emmanuel Macron.
The floor of Notre Dame Cathedral is filled with the workers involved in the 5 year project to restore the building following the devastating fire in 2019.
1/2
The floor of Notre Dame Cathedral is filled with the workers involved in the 5 year project to restore the building following the devastating fire in 2019.
1/2
Reposted by Susan Hafenstein
I am at that stage of this proposal where I think this is the best thing I’ve ever written and 5 minutes later, I think this is the worst thing I’ve ever written.
Somehow, both feelings are accurate
Somehow, both feelings are accurate
two men are standing in a park and one of them is asking the other " how is that possible "
ALT: two men are standing in a park and one of them is asking the other " how is that possible "
media.tenor.com
November 30, 2024 at 3:20 AM
I am at that stage of this proposal where I think this is the best thing I’ve ever written and 5 minutes later, I think this is the worst thing I’ve ever written.
Somehow, both feelings are accurate
Somehow, both feelings are accurate
Reposted by Susan Hafenstein
Greatly enjoying our ongoing #cryoET adventures. My new favourite way to procrastinate from administrative tasks is to play I spy with @bobcoelingh.bsky.social's recent data set! 👀
Here's an easy one! 👇
Here's an easy one! 👇
November 30, 2024 at 11:09 AM
Greatly enjoying our ongoing #cryoET adventures. My new favourite way to procrastinate from administrative tasks is to play I spy with @bobcoelingh.bsky.social's recent data set! 👀
Here's an easy one! 👇
Here's an easy one! 👇
Reposted by Susan Hafenstein
Reposted by Susan Hafenstein
HPV vaccines linked to drop in cervical cancer deaths www.cidrap.umn.edu/human-papill...
HPV vaccines linked to drop in cervical cancer deaths
From 2013-2015 to 2019-2021, mortality decreased 15% per year.
www.cidrap.umn.edu
November 27, 2024 at 9:28 PM
HPV vaccines linked to drop in cervical cancer deaths www.cidrap.umn.edu/human-papill...
Reposted by Susan Hafenstein
All the world's a phage:
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Hidden players: the bacteria-killing viruses of the gut microbiome
Viruses known as bacteriophages are difficult to study, but they are beginning to give up their secrets.
www.nature.com
November 27, 2024 at 5:08 PM
All the world's a phage:
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Susan Hafenstein
Canine parvovirus NS1 induces host translation shutoff by reducing mTOR phosphorylation journals.asm.org/doi/10.1128/...
Canine parvovirus NS1 induces host translation shutoff by reducing mTOR phosphorylation | Journal of Virology
Autonomous parvoviruses, which possess compact genomes, are obligate intracellular parasites that necessitate host cell division for their replication cycle. Consequently, the modulation of host translation and usurpation of cellular machinery are ...
journals.asm.org
November 27, 2024 at 6:20 PM
Canine parvovirus NS1 induces host translation shutoff by reducing mTOR phosphorylation journals.asm.org/doi/10.1128/...
Reposted by Susan Hafenstein
November 25, 2024 at 6:21 PM
Reposted by Susan Hafenstein
Polio has been detected in wastewater in NY for some time - so it’s out there and probably elsewhere too. For those of us on the older side who were vaccinated against polio decades ago, the CDC recommends a booster. Check with your healthcare provider to see if you should get one.
Polio Vaccine Recommendations
Find routine recommendations, accelerated schedules, other considerations for polio vaccine.
www.cdc.gov
November 17, 2024 at 1:38 PM
Polio has been detected in wastewater in NY for some time - so it’s out there and probably elsewhere too. For those of us on the older side who were vaccinated against polio decades ago, the CDC recommends a booster. Check with your healthcare provider to see if you should get one.